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List of works by Frédéric Blanchard

BYL719, a new α-specific PI3K inhibitor: single administration and in combination with conventional chemotherapy for the treatment of osteosarcoma

scientific article

Binding of leukemia inhibitory factor (LIF) to mutants of its low affinity receptor, gp190, reveals a LIF binding site outside and interactions between the two cytokine binding domains

scientific article published on 01 May 1999

Calcific tendonitis of the rotator cuff: From formation to resorption

scientific article published on 28 November 2017

Cathepsin-Mediated Alterations in TGFß-Related Signaling Underlie Disrupted Cartilage and Bone Maturation Associated With Impaired Lysosomal Targeting

scientific article published on 25 September 2015

Cellular activity and signaling induced by osteoprotegerin in osteoclasts: involvement of receptor activator of nuclear factor kappaB ligand and MAPK.

scientific article published on February 2004

Cytokine-Induced and Stretch-Induced Sphingosine 1-Phosphate Production by Enthesis Cells Could Favor Abnormal Ossification in Spondyloarthritis

scientific article published on 10 September 2019

DNA methylation controls the responsiveness of hepatoma cells to leukemia inhibitory factor.

scientific article

Direct anti-cancer effect of oncostatin M on chondrosarcoma.

scientific article published on 6 January 2011

Distinct expression of interleukin (IL)-36α, β and γ, their antagonist IL-36Ra and IL-38 in psoriasis, rheumatoid arthritis and Crohn's disease.

scientific article published on 23 December 2015

Epitope-function relationships of human leukemia inhibitory factor receptors using a novel set of anti-gp190 mAB.

scientific article

Histone deacetylase inhibitors: new drugs for the treatment of inflammatory diseases?

scientific article

Human interleukin for DA cells/leukemia inhibitory factor and oncostatin M enhance membrane expression of intercellular adhesion molecule-1 on melanoma cells but not the shedding of its soluble form.

scientific article published on February 1995

Human osteosarcoma cells express functional receptor activator of nuclear factor-kappa B.

scientific article published on April 2007

IL-1β and TNFα promote monocyte viability through the induction of GM-CSF expression by rheumatoid arthritis synovial fibroblasts

scientific article published on 17 November 2014

IL-38 overexpression induces anti-inflammatory effects in mice arthritis models and in human macrophages in vitro

scientific article published on 13 March 2017

IMQ-induced skin inflammation in mice is dependent on IL-1R1 and MyD88 signaling but independent of the NLRP3 inflammasome.

scientific article published on 6 July 2015

IMSYC immunologic synovitis score: A new score for synovial membrane characterization in inflammatory and non-inflammatory arthritis

scientific article published on 27 April 2018

Imatinib mesylate exerts anti-proliferative effects on osteosarcoma cells and inhibits the tumour growth in immunocompetent murine models

scientific article (publication date: 2014)

Immune Modulation by Transplanted Calcium Phosphate Biomaterials and Human Mesenchymal Stromal Cells in Bone Regeneration

scientific article published on 02 April 2019

Induction of osteogenesis in mesenchymal stem cells by activated monocytes/macrophages depends on oncostatin M signaling

scientific article

Interleukin 34 expression is associated with synovitis severity in rheumatoid arthritis patients

scientific article

Involvement of sphingosine kinase/sphingosine 1-phosphate metabolic pathway in spondyloarthritis

scientific article

Leukaemia inhibitory factor (lif) is expressed in hypertrophic chondrocytes and vascular sprouts during osteogenesis

scientific article published on 7 December 2002

Leukemia inhibitory factor (LIF) and oncastsin M (OSM) high affinity binding require additional receptor subunits besides GP130 and GP190.

scientific article published on March 1996

Mesenchymal stem cell transplantation and DMEM administration in a 3NP rat model of Huntington's disease: morphological and behavioral outcomes

scientific article published on 9 November 2010

Micro-RNAs in inflammatory arthritis: From physiopathology to diagnosis, prognosis and therapeutic opportunities

scientific article published on 27 February 2019

Modulation of LIF expression in human melanoma cells by oncostatin M

scientific article published in June 1995

Mutations in the immunoglobulin-like domain of gp190, the leukemia inhibitory factor (LIF) receptor, increase or decrease its affinity for LIF.

scientific article published on 24 February 2003

New chondrosarcoma cell lines and mouse models to study the link between chondrogenesis and chemoresistance.

scientific article published on 19 August 2013

Oncostatin M induces IL-33 expression in liver endothelial cells in mice and expands ST2+CD4+ lymphocytes

scientific article published on 6 August 2015

Oncostatin M is a growth factor for Ewing sarcoma

scientific article

Oncostatin M overexpression induces skin inflammation but is not required in the mouse model of imiquimod-induced psoriasis-like inflammation.

scientific article published on 12 May 2016

Oncostatin M regulates the synthesis and turnover of gp130, leukemia inhibitory factor receptor alpha, and oncostatin M receptor beta by distinct mechanisms.

scientific article published on 15 October 2001

Oncostatin m, an inflammatory cytokine produced by macrophages, supports intramembranous bone healing in a mouse model of tibia injury

scientific article published in March 2015

Origin licensing and programmed cell death: a hypothesis.

scientific article

Production and characterization of monoclonal antibodies against the leukemia inhibitory factor low affinity receptor, gp190 ⬇️

scientific article published on July 14, 1997

Recent advances in the management of osteosarcoma and forthcoming therapeutic strategies.

scientific article published on February 2007

Receptor subunit-specific action of oncostatin M in hepatic cells and its modulation by leukemia inhibitory factor

scientific article published on 01 August 2000

Response to: 'Does IL-38 act on macrophages and/or dendritic cells in arthritis?' by Jiang et al.

scientific article published on 12 June 2017

Rotator Cuff Tenocytes Differentiate into Hypertrophic Chondrocyte-Like Cells to Produce Calcium Deposits in an Alkaline Phosphatase-Dependent Manner

scientific article published on 26 September 2019

Sensitization of osteosarcoma cells to apoptosis by oncostatin M depends on STAT5 and p53.

scientific article published on 30 April 2007

Soluble mannose 6-phosphate/insulin-like growth factor II (IGF-II) receptor inhibits interleukin-6-type cytokine-dependent proliferation by neutralization of IGF-II.

scientific article published on 28 August 2003

Stimulation of leukemia inhibitory factor receptor degradation by extracellular signal-regulated kinase

scientific article (publication date: 15 September 2000)

The Bone Niche of Chondrosarcoma: A Sanctuary for Drug Resistance, Tumour Growth and also a Source of New Therapeutic Targets.

scientific article published on 22 May 2011

The enigmatic role of IL-38 in inflammatory diseases.

scientific article

The mannose 6-phosphate/insulin-like growth factor II receptor is a nanomolar affinity receptor for glycosylated human leukemia inhibitory factor.

scientific article

Therapeutic approach of primary bone tumours by bisphosphonates.

scientific article published on January 2010

Upmodulation of alpha v beta 1 integrin expression on human tumor cells by human interleukin for DA cells/leukemia inhibitory factor and oncostatin M: correlation with increased cell adhesion on fibronectin.

scientific article

Wnt5a is expressed in spondyloarthritis and exerts opposite effects on enthesis and bone in murine organ and cell cultures

article

Zoledronic acid potentiates mTOR inhibition and abolishes the resistance of osteosarcoma cells to RAD001 (Everolimus): pivotal role of the prenylation process.

scientific article published on 22 October 2010

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