List of works - Valeria Tosello

Absence of biallelic TCRgamma deletion predicts early treatment failure in pediatric T-cell acute lymphoblastic leukemia

scientific article

Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL.

scientific article

Alteration in calcium handling at the subcellular level in mdx myotubes.

scientific article

Beat-to-beat oscillations of mitochondrial [Ca2+] in cardiac cells

scientific article

CD40 activation of B-CLL cells is associated with augmented intracellular levels of CD79b and increased BCR expression in a subset of patients

scientific article published on 01 June 2005

Calcineurin and GSK-3 inhibition sensitizes T-cell acute lymphoblastic leukemia cells to apoptosis through X-linked inhibitor of apoptosis protein degradation.

scientific article published on 9 December 2015

Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with calcineurin inhibition to promote T-ALL cell death.

scientific article published on 10 June 2016

Chemokine receptor expression in EBV-associated lymphoproliferation in hu/SCID mice: implications for CXCL12/CXCR4 axis in lymphoma generation.

scientific article published on 28 September 2004

DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia

scientific article

Differential expression of CCR7 defines two distinct subsets of human memory CD4+CD25+ Tregs

scientific article published on 31 December 2007

Differential expression of constitutive and inducible proteasome subunits in human monocyte-derived DC differentiated in the presence of IFN-alpha or IL-4.

scientific article published on January 2009

Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia

scientific article

Epitope clustering in regions undergoing efficient proteasomal processing defines immunodominant CTL regions of a tumor antigen

scientific article published on 24 October 2006

Expression from cell type-specific enhancer-modified retroviral vectors after transduction: influence of marker gene stability

scientific article published on January 2002

Heterogeneous intracellular expression of B-cell receptor components in B-cell chronic lymphocytic leukaemia (B-CLL) cells and effects of CD79b gene transfer on surface immunoglobulin levels in a B-CLL-derived cell line.

scientific article published on September 2005

Interferon-alpha gene therapy by lentiviral vectors contrasts ovarian cancer growth through angiogenesis inhibition

scientific article

Interruption of tumor dormancy by a transient angiogenic burst within the tumor microenvironment.

scholarly article

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia

scientific article

Mutational and functional genetics mapping of chemotherapy resistance mechanisms in relapsed acute lymphoblastic leukemia

scientific article published on 19 October 2020

Notch3-mediated regulation of MKP-1 levels promotes survival of T acute lymphoblastic leukemia cells

scientific article published on 25 January 2011

Recombinant aequorin and green fluorescent protein as valuable tools in the study of cell signalling

scientific article

Recombinant aequorin as tool for monitoring calcium concentration in subcellular compartments.

scientific article

Recruitment of human umbilical vein endothelial cells and human primary fibroblasts into experimental tumors growing in SCID mice

scientific article published on 01 July 2003

Targeting nonclassical oncogenes for therapy in T-ALL.

scientific article

The TLX1 oncogene drives aneuploidy in T cell transformation

scientific article

The side population of ovarian cancer cells is a primary target of IFN-alpha antitumor effects.

scientific article

Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming.

scholarly article

WT1 mutations in T-ALL

scientific article published on 03 June 2009

List of works by Valeria Tosello

Absence of biallelic TCRgamma deletion predicts early treatment failure in pediatric T-cell acute lymphoblastic leukemia

Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL.

Alteration in calcium handling at the subcellular level in mdx myotubes.

Beat-to-beat oscillations of mitochondrial [Ca2+] in cardiac cells

CD40 activation of B-CLL cells is associated with augmented intracellular levels of CD79b and increased BCR expression in a subset of patients

Calcineurin and GSK-3 inhibition sensitizes T-cell acute lymphoblastic leukemia cells to apoptosis through X-linked inhibitor of apoptosis protein degradation.

Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with calcineurin inhibition to promote T-ALL cell death.

Chemokine receptor expression in EBV-associated lymphoproliferation in hu/SCID mice: implications for CXCL12/CXCR4 axis in lymphoma generation.

DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia

Differential expression of CCR7 defines two distinct subsets of human memory CD4+CD25+ Tregs

Differential expression of constitutive and inducible proteasome subunits in human monocyte-derived DC differentiated in the presence of IFN-alpha or IL-4.

Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia

Epitope clustering in regions undergoing efficient proteasomal processing defines immunodominant CTL regions of a tumor antigen

Expression from cell type-specific enhancer-modified retroviral vectors after transduction: influence of marker gene stability

Heterogeneous intracellular expression of B-cell receptor components in B-cell chronic lymphocytic leukaemia (B-CLL) cells and effects of CD79b gene transfer on surface immunoglobulin levels in a B-CLL-derived cell line.

Interferon-alpha gene therapy by lentiviral vectors contrasts ovarian cancer growth through angiogenesis inhibition

Interruption of tumor dormancy by a transient angiogenic burst within the tumor microenvironment.

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia

Mutational and functional genetics mapping of chemotherapy resistance mechanisms in relapsed acute lymphoblastic leukemia

Notch3-mediated regulation of MKP-1 levels promotes survival of T acute lymphoblastic leukemia cells

Recombinant aequorin and green fluorescent protein as valuable tools in the study of cell signalling

Recombinant aequorin as tool for monitoring calcium concentration in subcellular compartments.

Recruitment of human umbilical vein endothelial cells and human primary fibroblasts into experimental tumors growing in SCID mice

Targeting nonclassical oncogenes for therapy in T-ALL.

The TLX1 oncogene drives aneuploidy in T cell transformation

The side population of ovarian cancer cells is a primary target of IFN-alpha antitumor effects.

Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming.

WT1 mutations in T-ALL