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List of works by Vítor Seabra

An evaluation of the latest in vitro tools for drug metabolism studies

scientific article

Annealing as a tool for the optimization of lyophilization and ensuring of the stability of protein-loaded PLGA nanoparticles

scientific article published on 10 March 2016

Chitosan cross-linked docetaxel loaded EGF receptor targeted nanoparticles for lung cancer cells

scientific article

Chitosan-Based Nanoparticles as Delivery Systems of Therapeutic Proteins

scientific article published on January 1, 2012

Co-encapsulation of lyoprotectants improves the stability of protein-loaded PLGA nanoparticles upon lyophilization.

scientific article

Current approaches for TYMS polymorphisms and their importance in molecular epidemiology and pharmacogenetics

scientific article published on August 2013

Development and in vivo safety assessment of tenofovir-loaded nanoparticles-in-film as a novel vaginal microbicide delivery system

scientific article published on 17 August 2016

Dietary glycine blunts lung inflammatory cell influx following acute endotoxin

scientific article published on 01 August 2000

Effect of chitosan coating in overcoming the phagocytosis of insulin loaded solid lipid nanoparticles by mononuclear phagocyte system

article

Effect of cryoprotectants on the porosity and stability of insulin-loaded PLGA nanoparticles after freeze-drying

scientific article published on October 2012

Effect of freeze-drying, cryoprotectants and storage conditions on the stability of secondary structure of insulin-loaded solid lipid nanoparticles

scientific article published on 10 September 2013

Effect of the Freezing Step in the Stability and Bioactivity of Protein-Loaded PLGA Nanoparticles Upon Lyophilization

scientific article

Estrogen is involved in early alcohol-induced liver injury in a rat enteral feeding model

scientific article published on 01 January 2000

Gender differences in early alcohol-induced liver injury: role of CD14, NF-kappaB, and TNF-alpha

scientific article published on 01 April 2000

Genetic polymorphisms in low-dose methotrexate transporters: current relevance as methotrexate therapeutic outcome biomarkers

scientific article

Glycine and uridine prevent D-galactosamine hepatotoxicity in the rat: role of Kupffer cells

scientific article published on 01 March 1999

Mannose-functionalized solid lipid nanoparticles are effective in targeting alveolar macrophages

scientific article published on 8 December 2017

Metabolism is required for the expression of ecstasy-induced cardiotoxicity in vitro

scientific article

Modulation of taurine levels in the rat liver alters methylene dianiline hepatotoxicity

scientific article published on October 19, 1997

Moving toward personalized medicine in rheumatoid arthritis: SNPs in methotrexate intracellular pathways are associated with methotrexate therapeutic outcome

scientific article published on 27 September 2016

Nanoparticles-in-film for the combined vaginal delivery of anti-HIV microbicide drugs

scientific article published on 21 September 2016

Pharmacogenomics of Methotrexate Membrane Transport Pathway: Can Clinical Response to Methotrexate in Rheumatoid Arthritis Be Predicted?

scientific article published on 16 June 2015

Prediction of methotrexate clinical response in Portuguese rheumatoid arthritis patients: implication of MTHFR rs1801133 and ATIC rs4673993 polymorphisms

scientific article

Role of endotoxin in the hypermetabolic state after acute ethanol exposure

scientific article published on 01 December 1998

Role of key TYMS polymorphisms on methotrexate therapeutic outcome in portuguese rheumatoid arthritis patients

scientific article published in 2014

SLC19A1 80G allele as a biomarker of methotrexate-related gastrointestinal toxicity in Portuguese rheumatoid arthritis patients

scientific article published on 18 December 2013

SLC19A1, SLC46A1 and SLCO1B1 polymorphisms as predictors of methotrexate-related toxicity in Portuguese rheumatoid arthritis patients

scientific article published on 14 August 2014

Stability study perspective of the effect of freeze-drying using cryoprotectants on the structure of insulin loaded into PLGA nanoparticles

Synthesis and characterization of non-toxic and thermo-sensitive poly(N-isopropylacrylamide)-grafted cashew gum nanoparticles as a potential epirubicin delivery matrix.

scientific article published on 10 August 2016

Targeted Drug Delivery Systems for Lung Macrophages

scientific article

The age factor for mitoxantrone's cardiotoxicity: multiple doses render the adult mouse heart more susceptible to injury

scientific article published on 9 January 2015

The formulation of nanomedicines for treating tuberculosis

scientific article published on 21 April 2016

Thymidylate synthase polymorphisms are associated to therapeutic outcome of advanced non-small cell lung cancer patients treated with platinum-based chemotherapy

scientific article published on 20 February 2014

Toxicity of alpha-naphthylisothiocyanate in isolated hepatocytes: Possible role of taurine

scientific article published on 01 August 1994