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List of works by José Martínez-González

3-Hydroxy-3-methylglutaryl-coenzyme-A synthase from Blattella germanica. Cloning, expression, developmental pattern and tissue expression

scientific article

A major role for RCAN1 in atherosclerosis progression

scientific article published on 15 October 2013

A sudden increase in plasma epinephrine levels transiently enhances platelet deposition on severely damaged arterial wall--studies in a porcine model

scientific article published on 01 December 1999

Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes

scientific article

Angiotensin II differentially modulates cyclooxygenase-2, microsomal prostaglandin E2 synthase-1 and prostaglandin I2 synthase expression in adventitial fibroblasts exposed to inflammatory stimuli.

scientific article

Atherogenic concentrations of native low-density lipoproteins down-regulate nitric-oxide-synthase mRNA and protein levels in endothelial cells

scientific article published on 01 March 1998

Biología celular y molecular de las lesiones ateroscleróticas

scientific article published on 01 February 2001

Blattella germanica has two HMG-CoA synthase genes. Both are regulated in the ovary during the gonadotrophic cycle.

scientific article published on April 1994

Blood-borne tissue factor activity predicts major cerebrovascular events in patients undergoing carotid endarterectomy: results from a 1-year follow-up study.

scientific article published on 22 November 2007

C-reactive protein exerts angiogenic effects on vascular endothelial cells and modulates associated signalling pathways and gene expression

scientific article

CALU polymorphism A29809G affects calumenin availability involving vascular calcification

scientific article published on 28 March 2015

CCL20 is increased in hypercholesterolemic subjects and is upregulated by LDL in vascular smooth muscle cells: role of NF-κB.

scientific article

Carotid plaque, stroke pathogenesis, and CRP: treatment of ischemic stroke.

scientific article published on February 2008

Carotid plaque, stroke pathogenesis, and CRP: treatment of ischemic stroke.

scientific article published on June 2007

Cells in Cardiovascular Disease: Using Diversity to Confront Adversity

scientific article published on 29 September 2020

Cytochrome c oxidase subunit I from the cockroach Blattella germanica: cloning, developmental pattern and tissue expression

scientific article published in June 1994

Decreased pre-surgical CD34+/CD144+ cell number in patients undergoing coronary artery bypass grafting compared to coronary artery disease-free valvular patients.

scientific article published on 3 January 2012

Deficient p27 phosphorylation at serine 10 increases macrophage foam cell formation and aggravates atherosclerosis through a proliferation-independent mechanism.

scientific article

Deletion or Inhibition of NOD1 Favors Plaque Stability and Attenuates Atherothrombosis in Advanced Atherogenesis †

scientific article published on 10 September 2020

Differential cholesteryl ester accumulation in two human vascular smooth muscle cell subpopulations exposed to aggregated LDL: effect of PDGF-stimulation and HMG-CoA reductase inhibition

scientific article published on 01 June 1999

Differential intracellular trafficking of von Willebrand factor (vWF) and vWF propeptide in porcine endothelial cells lacking Weibel–Palade bodies and in human endothelial cells

scientific article published on 01 March 2003

Down-regulation of Fibulin-5 is associated with aortic dilation: role of inflammation and epigenetics.

scientific article

EPC adhesion to arteries from diabetic and non-diabetic patients: effect of pioglitazone.

scientific article published in January 2009

Efecto temprano de las estatinas después de un infarto de miocardio. ¿Se debe a los efectos pleiotrópicos?

scientific article published on 01 March 2006

Effect of eplerenone on hypertension-associated renal damage in rats: potential role of peroxisome proliferator activated receptor gamma (PPAR-γ)

scientific journal article

El receptor nuclear NOR-1 regula la activación de las células vasculares y el remodelado vascular en respuesta a estrés hemodinámico

scientific article published in March 2014

Emerging therapeutic strategies to enhance HDL function

scientific article published on 10 October 2011

Endogenous Expression of C-Reactive Protein Is Increased in Active (Ulcerated Noncomplicated) Human Carotid Artery Plaques

scientific article published on 06 April 2006

Endothelial Jag1-RBPJ signalling promotes inflammatory leucocyte recruitment and atherosclerosis.

scientific article published on 5 August 2016

Endothelial Krüppel-like factor 4 modulates pulmonary arterial hypertension

scientific article

Endothelium and vascular protection: an update

scientific article published in January 2002

Esterified Cholesterol Accumulation Induced by Aggregated LDL Uptake in Human Vascular Smooth Muscle Cells Is Reduced by HMG-CoA Reductase Inhibitors

scientific article published on 01 May 1998

Experimental and interventional dietary study in humans on the role of HDL fatty acid composition in PGI2 release and Cox-2 expression by VSMC.

scientific article published in September 2003

Expression and Cellular Localization of 15-Hydroxy-Prostaglandin-Dehydrogenase in Abdominal Aortic Aneurysm

scientific article published on 19 August 2015

Fibulin-5 is up-regulated by hypoxia in endothelial cells through a hypoxia-inducible factor-1 (HIF-1α)-dependent mechanism. ⬇️

scientific article

HDL-Induced Prostacyclin Release in Smooth Muscle Cells Is Dependent on Cyclooxygenase-2 (Cox-2)

scientific article published on 01 December 1997

HIF-1-mediated up-regulation of cardiotrophin-1 is involved in the survival response of cardiomyocytes to hypoxia.

scientific article

Heterogeneity of smooth muscle cells in advanced human atherosclerotic plaques: intimal smooth muscle cells expressing a fibroblast surface protein are highly activated by platelet-released products.

scientific article published in November 2001

High levels of homocysteine inhibit lysyl oxidase (LOX) and downregulate LOX expression in vascular endothelial cells

scientific article published in November 2004

Hu antigen R is required for NOX-1 but not NOX-4 regulation by inflammatory stimuli in vascular smooth muscle cells.

scientific article

HuR mediates the synergistic effects of angiotensin II and IL-1β on vascular COX-2 expression and cell migration

scientific article published on 27 March 2015

Human and porcine smooth muscle cells share similar proliferation dependence on the mevalonate pathway: implication for in vivo interventions in the porcine model

scientific article published on 01 November 1996

Hypoxia upregulates PGI-synthase and increases PGI₂ release in human vascular cells exposed to inflammatory stimuli

scientific article

Hypoxia-induced ROS signaling is required for LOX up-regulation in endothelial cells

scientific article published in June 2011

Imidazolineoxyl N-oxide induces COX-2 in endothelial cells: role of free radicals

scientific article published on 01 June 2012

Inactivation of nuclear factor-Y inhibits vascular smooth muscle cell proliferation and neointima formation

scientific article

Induction of histone deacetylases (HDACs) in human abdominal aortic aneurysm: therapeutic potential of HDAC inhibitors

scientific article

Inflammation inhibits vascular fibulin-5 expression: Involvement of transcription factor SOX9

scientific article published on 27 September 2016

Influence of statin use on endothelial function: from bench to clinics.

scientific article published on January 2007

Involvement of neuron-derived orphan receptor-1 (NOR-1) in LDL-induced mitogenic stimulus in vascular smooth muscle cells: role of CREB.

scientific article

LDL downregulates CYP51 in porcine vascular endothelial cells and in the arterial wall through a sterol regulatory element binding protein-2-dependent mechanism.

scientific article

LDL receptor-related protein mediates uptake of aggregated LDL in human vascular smooth muscle cells.

scientific article published on June 2000

Left and right ventricle late remodeling following myocardial infarction in rats.

scientific article published on 31 May 2013

Low density lipoproteins downregulate lysyl oxidase in vascular endothelial cells and the arterial wall.

scientific article published in September 2002

Lysyl Oxidase Induces Vascular Oxidative Stress and Contributes to Arterial Stiffness and Abnormal Elastin Structure in Hypertension: Role of p38MAPK.

scientific article published on 23 December 2016

Lysyl oxidase (LOX) down-regulation by TNFα: A new mechanism underlying TNFα-induced endothelial dysfunction

scientific article published on 01 August 2007

Lysyl oxidase (LOX) in vascular remodelling

scientific article published in 2014

Lysyl oxidase and endothelial dysfunction: mechanisms of lysyl oxidase down-regulation by pro-inflammatory cytokines.

scientific article published on January 2008

Lysyl oxidase overexpression accelerates cardiac remodeling and aggravates angiotensin II-induced hypertrophy

scientific article

Matrix metalloproteinase-10 is upregulated by thrombin in endothelial cells and increased in patients with enhanced thrombin generation

scientific article published on 17 September 2009

Mechanisms underlying the cardiovascular effects of COX-inhibition: benefits and risks

scientific article

Metalloproteinases and atherothrombosis: MMP-10 mediates vascular remodeling promoted by inflammatory stimuli.

scientific article published on January 2008

Mevalonate deprivation impairs IGF-I/insulin signaling in human vascular smooth muscle cells

scientific article published on 01 December 1997

Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm.

scientific article published on 16 October 2013

Modulation of ERG25 expression by LDL in vascular cells.

scientific article published in April 2003

Molecular cloning, developmental pattern and tissue expression of 3-hydroxy-3-methylglutaryl coenzyme A reductase of the cockroach Blattella germanica.

scientific article published on April 1993

NOR-1 is involved in VEGF-induced endothelial cell growth.

scientific article

NOR-1 modulates the inflammatory response of vascular smooth muscle cells by preventing NFκB activation

scientific article published on 20 December 2014

NOR-1/NR4A3 regulates the cellular inhibitor of apoptosis 2 (cIAP2) in vascular cells: role in the survival response to hypoxic stress

scientific article published on 22 September 2016

NR4A receptors up-regulate the antiproteinase alpha-2 macroglobulin (A2M) and modulate MMP-2 and MMP-9 in vascular smooth muscle cells

scientific article published in November 2015

Neovascularización en arterias coronarias humanas con distintos grados de lesión

scientific article published on 01 October 2003

Nestin(+) cells direct inflammatory cell migration in atherosclerosis.

scientific article

New challenges for a second-generation low-molecular-weight heparin: focus on bemiparin.

scientific article published on May 2010

New genetic association for the kinin system: the L-arginine connection. Insight: association of L-arginine levels and two loci in genes of the kallikrein-kinin system

scientific article published on 10 November 2016

Oleanolic acid induces prostacyclin release in human vascular smooth muscle cells through a cyclooxygenase-2-dependent mechanism

scientific article published on 01 March 2008

Over-expression of neuron-derived orphan receptor-1 (NOR-1) exacerbates neointimal hyperplasia after vascular injury.

scientific article

Plasma profiling by a protein array approach identifies IGFBP-1 as a novel biomarker of abdominal aortic aneurysm.

scientific article published on 25 January 2012

Prostacyclin induction by high-density lipoprotein (HDL) in vascular smooth muscle cells depends on sphingosine 1-phosphate receptors: Effect of simvastatin

scientific article published on 01 July 2008

Reendotelización, engrosamiento intimal y remodelado vascular. ¿Un denominador común?

scientific article published on 01 November 2000

Regulation of lysyl oxidase in vascular cells: lysyl oxidase as a new player in cardiovascular diseases.

scientific article published on 09 May 2008

Regulatory Effects of HDL on Smooth Muscle Cell Prostacyclin Release

scientific article published on 01 October 1999

Retinoic acid induces PGI synthase expression in human endothelial cells.

scientific article

Small oxidative changes in atherogenic LDL concentrations irreversibly regulate adhesiveness of human endothelial cells: effect of the lazaroid U74500A

scientific article published on 01 April 2000

Sphingosine-1-phosphate: A bioactive lipid that confers high-density lipoprotein with vasculoprotection mediated by nitric oxide and prostacyclin

scientific article published in April 2009

Sustained long-term improvement of arterial endothelial function in heterozygous familial hypercholesterolemia patients treated with simvastatin.

scientific article published in August 2001

Synergistic effect of thrombin and CD40 ligand on endothelial matrix metalloproteinase-10 expression and microparticle generation in vitro and in vivo.

scientific article published on 5 April 2012

Targeting p35/Cdk5 signalling via CIP-peptide promotes angiogenesis in hypoxia

scientific article

The NR4A subfamily of nuclear receptors: new early genes regulated by growth factors in vascular cells.

scientific article

The Role of Lysyl Oxidase Enzymes in Cardiac Function and Remodeling

scientific article published on 21 November 2019

The lysyl oxidase inhibitor (β-aminopropionitrile) reduces leptin profibrotic effects and ameliorates cardiovascular remodeling in diet-induced obesity in rats.

scientific article published on 15 January 2016

The lysyl oxidase inhibitor β-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats

scientific article published on 7 April 2015

The nuclear receptor NOR-1 regulates the small muscle protein, X-linked (SMPX) and myotube differentiation.

scientific article published on 16 May 2016

The nuclear receptor NOR-1/NR4A3 regulates the multifunctional glycoprotein vitronectin in human vascular smooth muscle cells.

scientific article published on 30 June 2017

The response of smooth muscle cells to alpha-thrombin depends on its arterial origin: comparison among different species

scientific article published in April 1998

The unsaponifiable fraction of virgin olive oil in chylomicrons from men improves the balance between vasoprotective and prothrombotic factors released by endothelial cells

scientific article published on 01 December 2004

Thrombin and protease-activated receptors (PARs) in atherothrombosis.

scientific article published in February 2008

Transcription factor SOX18 is expressed in human coronary atherosclerotic lesions and regulates DNA synthesis and vascular cell growth.

scientific article

Type II interleukin-1 receptor expression is reduced in monocytes/macrophages and atherosclerotic lesions

scientific article published on 12 June 2011

Vascular lysyl oxidase over-expression alters extracellular matrix structure and induces oxidative stress

scientific article published on 14 June 2017

[Development of coronary arteriosclerosis and its clinical complications]

scientific article published on 01 January 1995

miR-146a targets Fos expression in human cardiac cells

scientific article

miR-17 and -20a Target the Neuron-Derived Orphan Receptor-1 (NOR-1) in Vascular Endothelial Cells

scientific article published on 23 November 2015

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