List of works - Cristina Rodríguez

A major role for RCAN1 in atherosclerosis progression

scientific article published on 15 October 2013

Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes

scientific article

Angiotensin II differentially modulates cyclooxygenase-2, microsomal prostaglandin E2 synthase-1 and prostaglandin I2 synthase expression in adventitial fibroblasts exposed to inflammatory stimuli.

scientific article

C-reactive protein exerts angiogenic effects on vascular endothelial cells and modulates associated signalling pathways and gene expression

scientific article

CALU polymorphism A29809G affects calumenin availability involving vascular calcification

scientific article published on 28 March 2015

CCL20 is increased in hypercholesterolemic subjects and is upregulated by LDL in vascular smooth muscle cells: role of NF-κB.

scientific article

Circulating CCL20 as a New Biomarker of Abdominal Aortic Aneurysm.

scientific article published on 11 December 2017

Deficient p27 phosphorylation at serine 10 increases macrophage foam cell formation and aggravates atherosclerosis through a proliferation-independent mechanism.

scientific article

Deletion or Inhibition of NOD1 Favors Plaque Stability and Attenuates Atherothrombosis in Advanced Atherogenesis †

scientific article published on 10 September 2020

Differential induction of stearoyl-CoA desaturase and acyl-CoA oxidase genes by fibrates in HepG2 cells.

scientific article

Down-regulation of Fibulin-5 is associated with aortic dilation: role of inflammation and epigenetics.

scientific article

Effect of eplerenone on hypertension-associated renal damage in rats: potential role of peroxisome proliferator activated receptor gamma (PPAR-γ)

scientific journal article

El receptor nuclear NOR-1 regula la activación de las células vasculares y el remodelado vascular en respuesta a estrés hemodinámico

scientific article published in March 2014

Emerging Roles of Lysyl Oxidases in the Cardiovascular System: New Concepts and Therapeutic Challenges

scientific article published on 14 October 2019

Endothelial Jag1-RBPJ signalling promotes inflammatory leucocyte recruitment and atherosclerosis.

scientific article published on 5 August 2016

Endothelial Krüppel-like factor 4 modulates pulmonary arterial hypertension

scientific article

Endothelial NOD1 directs myeloid cell recruitment in atherosclerosis through VCAM-1

scientific article published on 29 November 2018

Enhanced endoplasmic reticulum and mitochondrial stress in abdominal aortic aneurysm

scientific article published on 05 July 2019

Expression and Cellular Localization of 15-Hydroxy-Prostaglandin-Dehydrogenase in Abdominal Aortic Aneurysm

scientific article published on 19 August 2015

Fatty acid composition in low-density lipoproteins from renal transplant recipients

scientific article published in September 1999

Fibulin-5 is up-regulated by hypoxia in endothelial cells through a hypoxia-inducible factor-1 (HIF-1α)-dependent mechanism. ⬇️

scientific article

HIF-1-mediated up-regulation of cardiotrophin-1 is involved in the survival response of cardiomyocytes to hypoxia.

scientific article

High levels of homocysteine inhibit lysyl oxidase (LOX) and downregulate LOX expression in vascular endothelial cells

scientific article published in November 2004

Hu antigen R is required for NOX-1 but not NOX-4 regulation by inflammatory stimuli in vascular smooth muscle cells.

scientific article

HuR mediates the synergistic effects of angiotensin II and IL-1β on vascular COX-2 expression and cell migration

scientific article published on 27 March 2015

Hypoxia upregulates PGI-synthase and increases PGI₂ release in human vascular cells exposed to inflammatory stimuli

scientific article

Hypoxia-induced ROS signaling is required for LOX up-regulation in endothelial cells

scientific article published in June 2011

Inactivation of nuclear factor-Y inhibits vascular smooth muscle cell proliferation and neointima formation

scientific article

Inflammation inhibits vascular fibulin-5 expression: Involvement of transcription factor SOX9

scientific article published on 27 September 2016

Inhibition of enzymes involved in collagen cross-linking reduces vascular smooth muscle cell calcification

scientific article published in August 2018

LDL downregulates CYP51 in porcine vascular endothelial cells and in the arterial wall through a sterol regulatory element binding protein-2-dependent mechanism.

scientific article

Left and right ventricle late remodeling following myocardial infarction in rats.

scientific article published on 31 May 2013

Low density lipoproteins downregulate lysyl oxidase in vascular endothelial cells and the arterial wall.

scientific article published in September 2002

Lysyl Oxidase Induces Vascular Oxidative Stress and Contributes to Arterial Stiffness and Abnormal Elastin Structure in Hypertension: Role of p38MAPK.

scientific article published on 23 December 2016

Lysyl oxidase (LOX) down-regulation by TNFα: A new mechanism underlying TNFα-induced endothelial dysfunction

scientific article published on 01 August 2007

Lysyl oxidase (LOX) in vascular remodelling

scientific article published in 2014

Lysyl oxidase (LOX) limits VSMC proliferation and neointimal thickening through its extracellular enzymatic activity

scientific article published in Scientific Reports

Lysyl oxidase and endothelial dysfunction: mechanisms of lysyl oxidase down-regulation by pro-inflammatory cytokines.

scientific article published on January 2008

Lysyl oxidase overexpression accelerates cardiac remodeling and aggravates angiotensin II-induced hypertrophy

scientific article

MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis.

scientific article published on 2 March 2018

Matrix metalloproteinase-10 is upregulated by thrombin in endothelial cells and increased in patients with enhanced thrombin generation

scientific article published on 17 September 2009

Mechanisms of vascular aging: What can we learn from Hutchinson-Gilford progeria syndrome?

scientific article published on 27 March 2018

Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm.

scientific article published on 16 October 2013

Modulation of ERG25 expression by LDL in vascular cells.

scientific article published in April 2003

NOR-1 modulates the inflammatory response of vascular smooth muscle cells by preventing NFκB activation

scientific article published on 20 December 2014

NOR-1/NR4A3 regulates the cellular inhibitor of apoptosis 2 (cIAP2) in vascular cells: role in the survival response to hypoxic stress

scientific article published on 22 September 2016

NR4A receptors up-regulate the antiproteinase alpha-2 macroglobulin (A2M) and modulate MMP-2 and MMP-9 in vascular smooth muscle cells

scientific article published in November 2015

Nestin(+) cells direct inflammatory cell migration in atherosclerosis.

scientific article

New challenges for a second-generation low-molecular-weight heparin: focus on bemiparin.

scientific article published on May 2010

Oleanolic acid induces prostacyclin release in human vascular smooth muscle cells through a cyclooxygenase-2-dependent mechanism

scientific article published on 01 March 2008

Opposite Effects of Moderate and Extreme Cx43 Deficiency in Conditional Cx43-Deficient Mice on Angiotensin II-Induced Cardiac Fibrosis

scientific article published on 22 October 2019

Over-expression of neuron-derived orphan receptor-1 (NOR-1) exacerbates neointimal hyperplasia after vascular injury.

scientific article

Oxidation of low-density lipoproteins in renal transplant recipients

scientific article published in September 1999

Oxidized Low-Density Lipoprotein Receptor in Lymphocytes Prevents Atherosclerosis and Predicts Subclinical Disease

scientific article published on 01 January 2019

Plasma profiling by a protein array approach identifies IGFBP-1 as a novel biomarker of abdominal aortic aneurysm.

scientific article published on 25 January 2012

Prostacyclin induction by high-density lipoprotein (HDL) in vascular smooth muscle cells depends on sphingosine 1-phosphate receptors: Effect of simvastatin

scientific article published on 01 July 2008

Regulation of lysyl oxidase in vascular cells: lysyl oxidase as a new player in cardiovascular diseases.

scientific article published on 09 May 2008

Retinoic acid induces PGI synthase expression in human endothelial cells.

scientific article

Sphingosine-1-phosphate: A bioactive lipid that confers high-density lipoprotein with vasculoprotection mediated by nitric oxide and prostacyclin

scientific article published in April 2009

Targeting p35/Cdk5 signalling via CIP-peptide promotes angiogenesis in hypoxia

scientific article

The Role of Lysyl Oxidase Enzymes in Cardiac Function and Remodeling

scientific article published on 21 November 2019

The lysyl oxidase inhibitor (β-aminopropionitrile) reduces leptin profibrotic effects and ameliorates cardiovascular remodeling in diet-induced obesity in rats.

scientific article published on 15 January 2016

The lysyl oxidase inhibitor β-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats

scientific article published on 7 April 2015

The nuclear receptor NOR-1 modulates redox homeostasis in human vascular smooth muscle cells

scientific article published on 07 August 2018

The nuclear receptor NOR-1 regulates the small muscle protein, X-linked (SMPX) and myotube differentiation.

scientific article published on 16 May 2016

The nuclear receptor NOR-1/NR4A3 regulates the multifunctional glycoprotein vitronectin in human vascular smooth muscle cells.

scientific article published on 30 June 2017

The role of mitochondrial oxidative stress in the metabolic alterations in diet-induced obesity in rats

scientific article published on 01 August 2019

Thrombin and protease-activated receptors (PARs) in atherothrombosis.

scientific article published in February 2008

Transcription factor SOX18 is expressed in human coronary atherosclerotic lesions and regulates DNA synthesis and vascular cell growth.

scientific article

Type II interleukin-1 receptor expression is reduced in monocytes/macrophages and atherosclerotic lesions

scientific article published on 12 June 2011

Vascular lysyl oxidase over-expression alters extracellular matrix structure and induces oxidative stress

scientific article published on 14 June 2017

Walnut-enriched diet increases the association of LDL from hypercholesterolemic men with human HepG2 cells.

scientific article published in December 2001

miR-146a targets Fos expression in human cardiac cells

scientific article

miR-17 and -20a Target the Neuron-Derived Orphan Receptor-1 (NOR-1) in Vascular Endothelial Cells

scientific article published on 23 November 2015

List of works by Cristina Rodríguez

A major role for RCAN1 in atherosclerosis progression

Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes

Angiotensin II differentially modulates cyclooxygenase-2, microsomal prostaglandin E2 synthase-1 and prostaglandin I2 synthase expression in adventitial fibroblasts exposed to inflammatory stimuli.

C-reactive protein exerts angiogenic effects on vascular endothelial cells and modulates associated signalling pathways and gene expression

CALU polymorphism A29809G affects calumenin availability involving vascular calcification

CCL20 is increased in hypercholesterolemic subjects and is upregulated by LDL in vascular smooth muscle cells: role of NF-κB.

Circulating CCL20 as a New Biomarker of Abdominal Aortic Aneurysm.

Deficient p27 phosphorylation at serine 10 increases macrophage foam cell formation and aggravates atherosclerosis through a proliferation-independent mechanism.

Deletion or Inhibition of NOD1 Favors Plaque Stability and Attenuates Atherothrombosis in Advanced Atherogenesis †

Differential induction of stearoyl-CoA desaturase and acyl-CoA oxidase genes by fibrates in HepG2 cells.

Down-regulation of Fibulin-5 is associated with aortic dilation: role of inflammation and epigenetics.

Effect of eplerenone on hypertension-associated renal damage in rats: potential role of peroxisome proliferator activated receptor gamma (PPAR-γ)

El receptor nuclear NOR-1 regula la activación de las células vasculares y el remodelado vascular en respuesta a estrés hemodinámico

Emerging Roles of Lysyl Oxidases in the Cardiovascular System: New Concepts and Therapeutic Challenges

Endothelial Jag1-RBPJ signalling promotes inflammatory leucocyte recruitment and atherosclerosis.

Endothelial Krüppel-like factor 4 modulates pulmonary arterial hypertension

Endothelial NOD1 directs myeloid cell recruitment in atherosclerosis through VCAM-1

Enhanced endoplasmic reticulum and mitochondrial stress in abdominal aortic aneurysm

Expression and Cellular Localization of 15-Hydroxy-Prostaglandin-Dehydrogenase in Abdominal Aortic Aneurysm

Fatty acid composition in low-density lipoproteins from renal transplant recipients

Fibulin-5 is up-regulated by hypoxia in endothelial cells through a hypoxia-inducible factor-1 (HIF-1α)-dependent mechanism. ⬇️

HIF-1-mediated up-regulation of cardiotrophin-1 is involved in the survival response of cardiomyocytes to hypoxia.

High levels of homocysteine inhibit lysyl oxidase (LOX) and downregulate LOX expression in vascular endothelial cells

Hu antigen R is required for NOX-1 but not NOX-4 regulation by inflammatory stimuli in vascular smooth muscle cells.

HuR mediates the synergistic effects of angiotensin II and IL-1β on vascular COX-2 expression and cell migration

Hypoxia upregulates PGI-synthase and increases PGI₂ release in human vascular cells exposed to inflammatory stimuli

Hypoxia-induced ROS signaling is required for LOX up-regulation in endothelial cells

Inactivation of nuclear factor-Y inhibits vascular smooth muscle cell proliferation and neointima formation

Inflammation inhibits vascular fibulin-5 expression: Involvement of transcription factor SOX9

Inhibition of enzymes involved in collagen cross-linking reduces vascular smooth muscle cell calcification

LDL downregulates CYP51 in porcine vascular endothelial cells and in the arterial wall through a sterol regulatory element binding protein-2-dependent mechanism.

Left and right ventricle late remodeling following myocardial infarction in rats.

Low density lipoproteins downregulate lysyl oxidase in vascular endothelial cells and the arterial wall.

Lysyl Oxidase Induces Vascular Oxidative Stress and Contributes to Arterial Stiffness and Abnormal Elastin Structure in Hypertension: Role of p38MAPK.

Lysyl oxidase (LOX) down-regulation by TNFα: A new mechanism underlying TNFα-induced endothelial dysfunction

Lysyl oxidase (LOX) in vascular remodelling

Lysyl oxidase (LOX) limits VSMC proliferation and neointimal thickening through its extracellular enzymatic activity

Lysyl oxidase and endothelial dysfunction: mechanisms of lysyl oxidase down-regulation by pro-inflammatory cytokines.

Lysyl oxidase overexpression accelerates cardiac remodeling and aggravates angiotensin II-induced hypertrophy

MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis.

Matrix metalloproteinase-10 is upregulated by thrombin in endothelial cells and increased in patients with enhanced thrombin generation

Mechanisms of vascular aging: What can we learn from Hutchinson-Gilford progeria syndrome?

Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm.

Modulation of ERG25 expression by LDL in vascular cells.

NOR-1 modulates the inflammatory response of vascular smooth muscle cells by preventing NFκB activation

NOR-1/NR4A3 regulates the cellular inhibitor of apoptosis 2 (cIAP2) in vascular cells: role in the survival response to hypoxic stress

NR4A receptors up-regulate the antiproteinase alpha-2 macroglobulin (A2M) and modulate MMP-2 and MMP-9 in vascular smooth muscle cells

Nestin(+) cells direct inflammatory cell migration in atherosclerosis.

New challenges for a second-generation low-molecular-weight heparin: focus on bemiparin.

Oleanolic acid induces prostacyclin release in human vascular smooth muscle cells through a cyclooxygenase-2-dependent mechanism

Opposite Effects of Moderate and Extreme Cx43 Deficiency in Conditional Cx43-Deficient Mice on Angiotensin II-Induced Cardiac Fibrosis

Over-expression of neuron-derived orphan receptor-1 (NOR-1) exacerbates neointimal hyperplasia after vascular injury.

Oxidation of low-density lipoproteins in renal transplant recipients

Oxidized Low-Density Lipoprotein Receptor in Lymphocytes Prevents Atherosclerosis and Predicts Subclinical Disease

Plasma profiling by a protein array approach identifies IGFBP-1 as a novel biomarker of abdominal aortic aneurysm.

Prostacyclin induction by high-density lipoprotein (HDL) in vascular smooth muscle cells depends on sphingosine 1-phosphate receptors: Effect of simvastatin

Regulation of lysyl oxidase in vascular cells: lysyl oxidase as a new player in cardiovascular diseases.

Retinoic acid induces PGI synthase expression in human endothelial cells.

Sphingosine-1-phosphate: A bioactive lipid that confers high-density lipoprotein with vasculoprotection mediated by nitric oxide and prostacyclin

Targeting p35/Cdk5 signalling via CIP-peptide promotes angiogenesis in hypoxia

The Role of Lysyl Oxidase Enzymes in Cardiac Function and Remodeling

The lysyl oxidase inhibitor (β-aminopropionitrile) reduces leptin profibrotic effects and ameliorates cardiovascular remodeling in diet-induced obesity in rats.

The lysyl oxidase inhibitor β-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats

The nuclear receptor NOR-1 modulates redox homeostasis in human vascular smooth muscle cells

The nuclear receptor NOR-1 regulates the small muscle protein, X-linked (SMPX) and myotube differentiation.

The nuclear receptor NOR-1/NR4A3 regulates the multifunctional glycoprotein vitronectin in human vascular smooth muscle cells.

The role of mitochondrial oxidative stress in the metabolic alterations in diet-induced obesity in rats

Thrombin and protease-activated receptors (PARs) in atherothrombosis.

Transcription factor SOX18 is expressed in human coronary atherosclerotic lesions and regulates DNA synthesis and vascular cell growth.

Type II interleukin-1 receptor expression is reduced in monocytes/macrophages and atherosclerotic lesions

Vascular lysyl oxidase over-expression alters extracellular matrix structure and induces oxidative stress

Walnut-enriched diet increases the association of LDL from hypercholesterolemic men with human HepG2 cells.

miR-146a targets Fos expression in human cardiac cells

miR-17 and -20a Target the Neuron-Derived Orphan Receptor-1 (NOR-1) in Vascular Endothelial Cells