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List of works by Maria Orietta Borghi

8-Cl-cAMP and PKA I-selective cAMP analogs effectively inhibit undifferentiated thyroid cancer cell growth.

scientific article published on 27 July 2016

A non-complement-fixing antibody to β2 glycoprotein I as a novel therapy for antiphospholipid syndrome.

scientific article

AB0830 Role of anti-IFI16 antibodies and NT-PROBNP as candidate biomarkers in systemic sclerosis

AB1013 Systemic Sclerosis and Myositis Extractable Nuclear Antigen (ENA) Analysis: Profile of A Cohort of Subjects with Isolated Raynaud's Phenomenon

AB1085 Empirical Approach to Investigate Raynaud's Phenomenon: The Pearl Study

Alterations in the immune system of children from mothers treated with immunosuppressive agents during pregnancy

scientific article (publication date: April 2004)

Anti-beta(2)-glycoprotein I ELISA assay: the influence of different antigen preparations.

scientific article published in April 2009

Anti-beta-2 glycoprotein I antibodies affect Bcl-2 and Bax trophoblast expression without evidence of apoptosis.

scientific article

Anti-endothelial cell IgG fractions from systemic lupus erythematosus patients bind to human endothelial cells and induce a pro-adhesive and a pro-inflammatory phenotype in vitro

scientific article published on January 1999

Anti-endothelial cell antibodies in patients with Wegener's granulomatosis and micropolyarteritis

scientific article published in January 1990

Anti-phosphatidylserine/prothrombin antibodies: an additional diagnostic marker for APS?

scientific article published in July 2013

Anti-phospholipid antibody mediated fetal loss: still an open question from a pathogenic point of view

scientific article published on 01 April 2010

Anti-phospholipid induced murine fetal loss: novel protective effect of a peptide targeting the β2 glycoprotein I phospholipid-binding site. Implications for human fetal loss.

scientific article published on 22 December 2011

Antibodies and Diagnostic Tests in Antiphospholipid Syndrome

Antibodies to endothelial cells in primary vasculitides mediate in vitro endothelial cytotoxicity in the presence of normal peripheral blood mononuclear cells.

scientific article published on June 1992

Antiendothelial Cell Antibodies

scientific article published in 2014

Antiendothelial cell antibodies in primary vasculitides

scientific article published on 01 January 1991

Antiphospholipid Antibodies and Infertility: A Gene Expression Study in Decidual Stromal Cells

scientific article published on March 2016

Antiphospholipid and antiendothelial antibodies

scientific article

Antiphospholipid antibodies and the antiphospholipid syndrome: pathogenic mechanisms

scientific article published on April 2008

Antiphospholipid antibodies cross-reacting with erythrocyte membranes. A case report

scientific article published on 01 July 1992

Antiphospholipid antibodies detected by line immunoassay differentiate among patients with antiphospholipid syndrome, with infections and asymptomatic carriers.

scientific article published on 21 May 2016

Antitumor activity of interferon-β1a in hormone refractory prostate cancer with neuroendocrine differentiation.

scientific article

Association of pyoderma gangrenosum, acne, and suppurative hidradenitis (PASH) shares genetic and cytokine profiles with other autoinflammatory diseases

scientific article

Association ofSTAT4andBLK, but notBANK1orIRF5, with primary antiphospholipid syndrome

Autoantibodies against beta 2-microglobulin-free HLA antigens in AIDS patients

scientific article published on 01 October 1993

Autoantibodies to fibroblasts induce a proadhesive and proinflammatory fibroblast phenotype in patients with systemic sclerosis

scientific article published on 01 June 2002

Autoantibody profiling in APS

scientific article published on 01 October 2014

Automated interpretation of ANCA patterns - a new approach in the serology of ANCA-associated vasculitis.

scientific article published on 14 December 2012

Automated tests of ANA immunofluorescence as throughput autoantibody detection technology: strengths and limitations

scientific article

Beta-endorphin content in HIV-infected HuT78 cell line and in peripheral lymphocytes from HIV-positive subjects.

scientific article published on January 1994

Beyond thrombosis: Anti-β2GPI domain 1 antibodies identify late pregnancy morbidity in anti-phospholipid syndrome

scientific article published on 14 February 2018

Blood Cell-Bound C4d as a Marker of Complement Activation in Patients With the Antiphospholipid Syndrome

scientific article published on 12 April 2019

Combination of mutant EL-4 thymoma cells and EBV-infection in B lymphocyte activation a) EBV-infection of EL-4-activated lymphocytes. b) Use of EL-4 cells as feeders for lymphoblastoid cell lines

scientific article published on September 1990

Complement Activation and Thrombin Generation by MBL Bound to β2-Glycoprotein I

scientific article published on 05 August 2020

Complement activation in antiphospholipid syndrome and its inhibition to prevent rethrombosis after arterial surgery

scientific article published on 07 December 2015

Correction: Simultaneous Automated Screening and Confirmatory Testing for Vasculitis-Specific ANCA.

scientific article published on 13 May 2015

Corrigendum to “Immune parameters identify Italian centenarians with a longer five-year survival independent of their health and functional status” [Exp. Gerontol. 54C (2014) 14–20]

article

Decreased expression of heparin-binding epidermal growth factor-like growth factor as a newly identified pathogenic mechanism of antiphospholipid-mediated defective placentation

scientific article published on 01 May 2010

Detection of anti-adalimumab antibodies in a RA responsive cohort of patients using three different techniques

scientific article published on 22 November 2018

Detection of early endothelial damage in patients with Raynaud's phenomenon

scientific article published on 24 April 2017

Diagnostic laboratory tests for systemic autoimmune rheumatic diseases: unmet needs towards harmonization

scientific article published on 01 September 2018

Effect of subcutaneous thymopentin treatment in drug addicts with persistent generalized lymphadenopathy

scientific article

Effects of human recombinant type I IFNs (IFN-α2b and IFN-β1a) on growth and migration of primary endometrial stromal cells from women with deeply infiltrating endometriosis: A preliminary study

scientific article published on 03 October 2018

Endothelial cell activation by antiphospholipid antibodies

scientific article published in August 2004

Endothelium activation in the anti-phospholipid syndrome

scientific article

Enrichment of IgG anti-DNA-producing lymphoblastoid cell lines by antigen-coated immunomagnetic beads

scientific article published on October 1992

European Forum on Antiphospholipid Antibodies: research in progress

scientific article published on September 2009

Everolimus is an active agent in medullary thyroid cancer: a clinical and in vitro study.

scientific article published on July 2012

FK-506 prevents diabetes in diabetes-prone BB/Wor rats

scientific article published on 01 January 1991

FRI0403 How early starts increased collagen synthesis in systemic sclerosis?

Fibrosis biomarkers in isolated Raynaud's phenomenon: too little, too soon?

scientific article published on 16 December 2013

Gene-specific mitochondria dysfunctions in human TARDBP and C9ORF72 fibroblasts.

scientific article published on 5 May 2016

HIBISCUS: HYDROXYCHLOROQUINE FOR THE SECONDARY PREVENTION OF THROMBOTIC AND OBSTETRICAL EVENTS IN PRIMARY ANTIPHOSPHOLIPID SYNDROME

scientific article published on 12 October 2018

Haemostatic and inflammatory biomarkers in advanced chronic heart failure: role of oral anticoagulants and successful heart transplantation

scientific article published in July 2004

Heterogeneity of immune responsiveness in healthy elderly subjects

scientific article published on 01 May 1988

Human monoclonal anti-endothelial cell IgG-derived from a systemic lupus erythematosus patient binds and activates human endothelium in vitro

scientific article published on 01 March 2001

Humoral autoimmunity against endothelium: theory or reality?

scientific article

IRF5 is associated with primary antiphospholipid syndrome, but is not a major risk factor

Imbalance of osteoclastogenesis-regulating factors in patients with celiac disease.

scientific article

Immune complexes containing scleroderma-specific autoantibodies induce a profibrotic and proinflammatory phenotype in skin fibroblasts

scientific article published on 29 August 2018

Immune function in children born to mothers with autoimmune diseases and exposed in utero to immunosuppressants

scientific article

Immune parameters identify Italian centenarians with a longer five-year survival independent of their health and functional status.

scientific article published on 31 January 2014

Immunopharmacological activity of cefodizime in young and elderly subjects: in vitro and ex vivo studies

scientific article published on 01 January 1992

Immunosuppressive activity of 15-deoxyspergualin on normal and autoimmune peripheral blood mononuclear cells

scientific article

Impaired serum cholesterol efflux capacity in rheumatoid arthritis and systemic lupus erythematosus

scientific article published on 05 April 2013

In utero exposure to Azathioprine in autoimmune disease. Where do we stand?

scientific article published on 30 March 2020

In vitro and ex vivo effect of tiaprofenic acid on human peripheral blood mononuclear cells

scientific article published on 01 October 1992

In vitro production of type 1 and type 2 cytokines by peripheral blood mononuclear cells from high-risk HIV-negative intravenous drug users

scientific article published on July 1995

In vitro type-1 and type-2 cytokine production in systemic lupus erythematosus: lack of relationship with clinical disease activity

scientific article published on 01 April 1996

In vivo distribution of β2 glycoprotein I under various pathophysiologic conditions.

scientific article published on 26 July 2011

In vivo immunopotentiating activity of thymopentin in aging humans: increase of IL-2 production

scientific article published on 01 February 1987

In vivo immunopotentiating activity of thymopentin in aging humans: modulation of IL-2 receptor expression

scientific article published on 01 August 1988

In vivo treatment with a monoclonal antibody to interferon-gamma neither affects the survival nor the incidence of lupus-nephritis in the MRL/lpr-lpr mouse

scientific article

Inflammatory response and the endothelium.

scientific article published in January 2004

Innate immunity in the antiphospholipid syndrome: role of toll-like receptors in endothelial cell activation by antiphospholipid antibodies

scientific article

Interaction between chronically HIV-infected promonocytic cells and human umbilical vein endothelial cells: role of proinflammatory cytokines and chemokines in viral expression modulation.

scientific article published in April 2000

Interferon-inducible genes, TNF-related apoptosis-inducing ligand (TRAIL) and interferon inducible protein 27 (IFI27) are negatively regulated in leiomyomas: implications for a role of the interferon pathway in leiomyoma development.

scientific article

Interleukin 2 enhancement of anti-T3-induced lymphocyte activation: standardization and use of this model in immunocompromized elderly subjects

scientific article

New insight into antiphospholipid syndrome: antibodies to β2glycoprotein I-domain 5 fail to induce thrombi in rats

scholarly article by Paolo Durigutto et al published April 2019 in Haematologica

Newly Identified Antiatherosclerotic Activity of Methotrexate and Adalimumab: Complementary Effects on Lipoprotein Function and Macrophage Cholesterol Metabolism

scientific article published on 01 May 2015

Obstetric and vascular APS: same autoantibodies but different diseases?

scientific article published on June 2012

Obstetric and vascular antiphospholipid syndrome: same antibodies but different diseases?

scientific article published on 01 July 2018

Only monospecific anti-DFS70 antibodies aid in the exclusion of antinuclear antibody associated rheumatic diseases: an Italian experience

scientific article published on 01 October 2019

Oxidation of β2-glycoprotein I associates with IgG antibodies to domain I in patients with antiphospholipid syndrome

scientific article published on 19 October 2017

Pathogenesis of antiphospholipid syndrome: understanding the antibodies ⬇️

scientific article published on May 10, 2011

Pathogenic Role of Complement in Antiphospholipid Syndrome and Therapeutic Implications.

scientific article

Patients with antiphospholipid syndrome display endothelial perturbation

Persistent generalized lymphadenopathy in drug addicts: immunological studies

scientific article published in January 1986

Pitfalls of antinuclear antibody detection in systemic lupus erythematosus: the positive experience of a national multicentre study

scientific article published on 25 April 2018

Preliminary evaluation of the first international reference preparation for anticitrullinated peptide antibodies

scientific article published on 4 April 2012

Prevalence and clinical significance of anti-cyclic citrullinated peptide antibodies in juvenile idiopathic arthritis.

scientific article published on July 2002

Prevalence of autoantibodies against structure specific recognition protein 1 in systemic lupus erythematosus

scientific article published on 01 January 2004

Prevalence, specificity, and clinical association of anti-phospholipid antibodies in COVID-19 patients: are the antibodies really guilty?

scientific article published on 19 June 2020

Prevention of cyclophosphamide-induced diabetes in the NOD/WEHI mouse with deoxyspergualin

scientific article published on 01 February 1993

Pro-inflammatory genotype as a risk factor for aPL-associated thrombosis: Report of a family with multiple anti-phospholipid positive members

scientific article

Protection from experimental autoimmune thyroiditis in CBA mice with the novel immunosuppressant deoxyspergualin

scientific article published on 01 March 1994

Relationship between anti-phospholipid and anti-endothelial cell antibodies III: beta 2 glycoprotein I mediates the antibody binding to endothelial membranes and induces the expression of adhesion molecules

scientific article published on 01 March 1995

Relationship between anti-phospholipid and anti-endothelial cell antibodies: further characterization of the reactivity on resting and cytokine-activated endothelial cells

scientific article published on 01 January 1992

Role of anti-beta2 glycoprotein I antibodies in antiphospholipid syndrome: in vitro and in vivo studies

scientific article published on February 2007

Role of anti-β2 glycoprotein I antibodies in antiphospholipid syndromeglycoprotein I antibodies in antiphospholipid syndrome

scientific article published in February 2007

Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies

scientific article (publication date: May 2003)

Serum chemerin in systemic sclerosis: a novel marker of early diffuse disease?

scientific article published on 29 September 2017

Silybin inhibition of human T-lymphocyte activation

scientific article published on 01 January 1988

Simultaneous automated screening and confirmatory testing for vasculitis-specific ANCA.

scientific article

Standardization of autoantibody testing: a paradigm for serology in rheumatic diseases

scientific article

Study on the interference of ticlopidine on the immune system

scientific article published on 01 January 1988

Successful sequential therapy with rituximab and belimumab in patients with active systemic lupus erythematosus: a case series

scientific article published on 27 February 2018

Synergisms between different activation pathways in adult and aged human lymphocytes

scientific article published in July 1989

Synergistic activity of everolimus and 5-aza-2'-deoxycytidine in medullary thyroid carcinoma cell lines.

scientific article published on 28 April 2017

TH1 and TH2 cytokine production by peripheral blood mononuclear cells from HIV-infected patients

article

The cAMP analogs have potent anti-proliferative effects on medullary thyroid cancer cell lines.

scientific article

The challenges of lupus anticoagulants

scientific article

The effects of deoxyspergualin on the development of diabetes in diabetes-prone BB rats

scientific article published on 01 September 1992

The story of the murine antiendothelial monoclonal antibody BGM. From patients' bedside to laboratory bench and from animal models to patients

scientific article

Toll-like receptor 4 and β2 glycoprotein I interaction on endothelial cells

scientific article published on 01 October 2014

Toll-like receptor and antiphospholipid mediated thrombosis: in vivo studies

scientific article

Toll-like receptors: another player in the pathogenesis of the anti-phospholipid syndrome

scientific article published on October 2008

Transforming growth factor beta1 in the pathogenesis of autoimmune congenital complete heart block: lesson from twins and triplets discordant for the disease

scientific article published on 01 January 2006

Two Novel Technologies for the Detection of Anti-cardiolipin and Anti β2-Glycoprotein Antibodies in the Real Life: Chemiluminescent in Comparison to the Addressable Laser Bead Immunoassays

scientific article published on 12 August 2019

Understanding and interpreting antinuclear antibody tests in systemic rheumatic diseases

scientific article published on 05 November 2020

Update on the pathogenesis and treatment of the antiphospholipid syndrome.

scientific article published on September 2015

Updating on the pathogenic mechanisms 5 of the antiphospholipid antibodies-associated pregnancy loss

scientific article published on June 2008

[Effect of pidotimod on the function of the human immune system: in vitro and ex vivo study]

scientific article published on 01 January 1993

β2 Glycoprotein I Recognition Drives Th1 Inflammation in Atherosclerotic Plaques of Patients with Primary Antiphospholipid Syndrome

scientific article published on 13 February 2017

β2-glycoprotein I, lipopolysaccharide and endothelial TLR4: three players in the two hit theory for anti-phospholipid-mediated thrombosis.

scientific article published on 27 March 2014

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