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List of works by Jack Hutcheson

Adipokines influence the inflammatory balance in autoimmunity

scientific article published on June 2015

Adverse effects of simulated hyper- and hypo-phosphatemia on endothelial cell function and viability

scientific article

BH3-only proteins in rheumatoid arthritis: potential targets for therapeutic intervention.

scientific article

Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis

scientific article published on 01 October 2006

Bim-Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis

scientific article

Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation

scientific article

Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity

scientific article published on 01 February 2008

Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis

scientific journal article

Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner.

scientific article

Endothelial overexpression of Fas ligand decreases atherosclerosis in apolipoprotein E-deficient mice

scientific article

Heightened cleavage of Axl receptor tyrosine kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE.

scientific article published on 26 May 2016

Immunologic and Metabolic Features of Pancreatic Ductal Adenocarcinoma Define Prognostic Subtypes of Disease.

scientific article published on 8 February 2016

Loss of Bim results in abnormal accumulation of mature CD4-CD8-CD44-CD25- thymocytes

scientific article

Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus ⬇️

scientific article published on November 8, 2012

Murine lupus strains differentially model unique facets of human lupus serology

scientific article published on 01 May 2012

Peritoneal catheter implantation elicits IL-10-producing immune-suppressor macrophages through a MyD88-dependent pathway

scientific article published on 17 January 2012

Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis.

scientific article

RB tumor suppressive function in response to xenobiotic hepatocarcinogens

scientific journal article

Requirement of myeloid cell-specific Fas expression for prevention of systemic autoimmunity in mice

scientific article published on March 2012

Retinoblastoma protein potentiates the innate immune response in hepatocytes: significance for hepatocellular carcinoma.

scientific article published on 28 August 2014

The CDK domain of p21 is a suppressor of IL-1beta-mediated inflammation in activated macrophages

scientific article published on March 2009

p21Cip1 is required for the development of monocytes and their response to serum transfer-induced arthritis

scientific article

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