List of works - Gianluca Bossi

Abscopal effect of radiation therapy: Interplay between radiation dose and p53 status

scientific article published on 6 February 2014

Approaching the challenges of MKK3/p38delta MAPK targeting for therapeutic purpose in colorectal cancer

scientific article published on 27 December 2019

Che-1 promotes tumor cell survival by sustaining mutant p53 transcription and inhibiting DNA damage response activation.

scientific article published on August 2010

Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy

scientific article published on 14 March 2015

Corrigendum

correction published 2015-02-04

Cytokine Modulation in Breast Cancer Patients Undergoing Radiotherapy: A Revision of the Most Recent Studies

scientific article published on 17 January 2019

Degradation of mutant p53H175 protein by Zn(II) through autophagy.

scientific article

Evidences that leptin up-regulates E-cadherin expression in breast cancer: effects on tumor growth and progression.

scientific article published in April 2007

HER3 targeting of adenovirus by fiber modification increases infection of breast cancer cells in vitro, but not following intratumoral injection in mice.

scientific article published on 26 October 2012

In vivo and in vitro evidence that PPARγ ligands are antagonists of leptin signaling in breast cancer

scientific article

Inhibition of Leydig tumor growth by farnesoid X receptor activation: the in vitro and in vivo basis for a novel therapeutic strategy.

scientific article

Inhibition of p85, the non-catalytic subunit of phosphatidylinositol 3-kinase, exerts potent antitumor activity in human breast cancer cells.

scientific article published on 6 December 2012

Insights of Crosstalk between p53 Protein and the MKK3/MKK6/p38 MAPK Signaling Pathway in Cancer.

scientific article

Leptin mediates tumor-stromal interactions that promote the invasive growth of breast cancer cells

scientific article

MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma.

scientific article

MKK3 sustains cell proliferation and survival through p38DELTA MAPK activation in colorectal cancer

scientific article published on 06 November 2019

Molecular imaging of nuclear factor-Y transcriptional activity maps proliferation sites in live animals.

scientific article published on 29 February 2012

Mutant p53 gains new function in promoting inflammatory signals by repression of the secreted interleukin-1 receptor antagonist.

scientific article

Mutant p53 inhibits miRNA biogenesis by interfering with the microprocessor complex.

scientific article

Mutant p53-induced up-regulation of mitogen-activated protein kinase kinase 3 contributes to gain of function

scientific article

PKC theta ablation improves healing in a mouse model of muscular dystrophy

scientific article

Restoration of wild-type p53 function in human cancer: relevance for tumor therapy.

scientific article published on March 2007

Restoring wtp53 activity in HIPK2 depleted MCF7 cells by modulating metallothionein and zinc.

scientific article

Retinoic acid and cAMP differentially regulate human chromogranin A promoter activity during differentiation of neuroblastoma cells.

scientific article published on January 1995

SEMA6A/RhoA/YAP axis mediates tumor-stroma interactions and prevents response to dual BRAF/MEK inhibition in BRAF-mutant melanoma

scientific article published on 19 April 2022

Ser58 of mouse p53 is the homologue of human Ser46 and is phosphorylated by HIPK2 in apoptosis

scientific article published on 26 May 2006

Slug (SNAI2) down-regulation by RNA interference facilitates apoptosis and inhibits invasive growth in neuroblastoma preclinical models

scientific article

Targeting MKK3 as a novel anticancer strategy: molecular mechanisms and therapeutical implications.

scientific article

The beneficial effect of Zinc(II) on low-dose chemotherapeutic sensitivity involves p53 activation in wild-type p53-carrying colorectal cancer cells

scientific article

The p38 MAPK Signaling Activation in Colorectal Cancer upon Therapeutic Treatments

scientific article published on 16 April 2020

Wild-type p53 gene transfer is not detrimental to normal cells in vivo: implications for tumor gene therapy

scientific article published in January 2004

List of works by Gianluca Bossi

Abscopal effect of radiation therapy: Interplay between radiation dose and p53 status

Approaching the challenges of MKK3/p38delta MAPK targeting for therapeutic purpose in colorectal cancer

Che-1 promotes tumor cell survival by sustaining mutant p53 transcription and inhibiting DNA damage response activation.

Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy

Corrigendum

Cytokine Modulation in Breast Cancer Patients Undergoing Radiotherapy: A Revision of the Most Recent Studies

Degradation of mutant p53H175 protein by Zn(II) through autophagy.

Evidences that leptin up-regulates E-cadherin expression in breast cancer: effects on tumor growth and progression.

HER3 targeting of adenovirus by fiber modification increases infection of breast cancer cells in vitro, but not following intratumoral injection in mice.

In vivo and in vitro evidence that PPARγ ligands are antagonists of leptin signaling in breast cancer

Inhibition of Leydig tumor growth by farnesoid X receptor activation: the in vitro and in vivo basis for a novel therapeutic strategy.

Inhibition of p85, the non-catalytic subunit of phosphatidylinositol 3-kinase, exerts potent antitumor activity in human breast cancer cells.

Insights of Crosstalk between p53 Protein and the MKK3/MKK6/p38 MAPK Signaling Pathway in Cancer.

Leptin mediates tumor-stromal interactions that promote the invasive growth of breast cancer cells

MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma.

MKK3 sustains cell proliferation and survival through p38DELTA MAPK activation in colorectal cancer

Molecular imaging of nuclear factor-Y transcriptional activity maps proliferation sites in live animals.

Mutant p53 gains new function in promoting inflammatory signals by repression of the secreted interleukin-1 receptor antagonist.

Mutant p53 inhibits miRNA biogenesis by interfering with the microprocessor complex.

Mutant p53-induced up-regulation of mitogen-activated protein kinase kinase 3 contributes to gain of function

PKC theta ablation improves healing in a mouse model of muscular dystrophy

Restoration of wild-type p53 function in human cancer: relevance for tumor therapy.

Restoring wtp53 activity in HIPK2 depleted MCF7 cells by modulating metallothionein and zinc.

Retinoic acid and cAMP differentially regulate human chromogranin A promoter activity during differentiation of neuroblastoma cells.

SEMA6A/RhoA/YAP axis mediates tumor-stroma interactions and prevents response to dual BRAF/MEK inhibition in BRAF-mutant melanoma

Ser58 of mouse p53 is the homologue of human Ser46 and is phosphorylated by HIPK2 in apoptosis

Slug (SNAI2) down-regulation by RNA interference facilitates apoptosis and inhibits invasive growth in neuroblastoma preclinical models

Targeting MKK3 as a novel anticancer strategy: molecular mechanisms and therapeutical implications.

The beneficial effect of Zinc(II) on low-dose chemotherapeutic sensitivity involves p53 activation in wild-type p53-carrying colorectal cancer cells

The p38 MAPK Signaling Activation in Colorectal Cancer upon Therapeutic Treatments

Wild-type p53 gene transfer is not detrimental to normal cells in vivo: implications for tumor gene therapy