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List of works by Steven A Stacker

A Simple Bioassay for the Evaluation of Vascular Endothelial Growth Factors

scientific article published on 15 March 2016

A Three-Dimensional Lymphatic Endothelial Cell Tube Formation Assay to Identify Novel Kinases Involved in Lymphatic Vessel Remodeling

scientific article

A fully human inhibitory monoclonal antibody to the Wnt receptor RYK

scientific article

A new breast carcinoma antigen defined by a monoclonal antibody

scientific article published on 01 November 1985

A phase Ib/II translational study of sunitinib with neoadjuvant radiotherapy in soft-tissue sarcoma

scientific article

A role for bone morphogenetic protein-4 in lymph node vascular remodeling and primary tumor growth

scientific article

A study of VEGF and its receptors in two rat models of proteinuria

scientific article published on 01 January 2004

A system for quantifying the patterning of the lymphatic vasculature

scientific article published on 01 December 2007

Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart

scientific article published on 16 February 2004

Adenovirus encoding vascular endothelial growth factor-D induces tissue-specific vascular patterns in vivo.

scientific article published in June 2002

Angiogenic Responses of Vascular Endothelial Growth Factors in Periadventitial Tissue

article

Arap3 is dysregulated in a mouse model of hypotrichosis-lymphedema-telangiectasia and regulates lymphatic vascular development.

scientific article

Association between suicide reporting in the media and suicide: systematic review and meta-analysis

scientific article published on 18 March 2020

Association of Increased Youth Suicides in the United States With the Release of 13 Reasons Why

scientific article published on 29 May 2019

Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers

scientific article (publication date: 5 November 1999)

Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis

scientific article published on 12 February 2014

Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination

scientific article

Counting nuclei released from microcarrier-based cultures using pro-fluorescent nucleic acid stains and volumetric flow cytometry.

scientific article published in July 2017

Current strategies for modulating lymphangiogenesis signalling pathways in human disease.

scientific article

Deletion of vascular endothelial growth factor C (VEGF-C) and VEGF-D is not equivalent to VEGF receptor 3 deletion in mouse embryos

scientific article published on 2 June 2008

Detection of mammary serum antigen in sera from breast cancer patients using monoclonal antibody 3E1.2.

scientific article published on 01 December 1988

Differential Receptor Binding and Regulatory Mechanisms for the Lymphangiogenic Growth Factors Vascular Endothelial Growth Factor (VEGF)-C and -D.

scientific article

Distinct roles of vascular endothelial growth factor-D in lymphangiogenesis and metastasis

scientific article published on April 2007

EGFR blockade with ZD1839 ("Iressa") potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma. Epidermal growth factor receptor

scientific article

Emerging Roles for VEGF-D in Human Disease

scientific article published on 4 January 2018

Evaluation of MSA as a serum marker in breast cancer: A comparison with CEA ⬇️

scientific article published on March 1, 1988

Exploring the role of endothelium in the tumour response to anti-angiogenic therapy.

scientific article

Expression and purification of bioactive, low-endotoxin recombinant human vitronectin

scientific article published on 01 June 2014

Expression of vascular endothelial growth factor receptor-3 by lymphatic endothelial cells is associated with lymph node metastasis in prostate cancer

scientific article published on August 2004

Focus on lymphangiogenesis in tumor metastasis.

scientific article

From anti-angiogenesis to anti-lymphangiogenesis: emerging trends in cancer therapy.

scientific article published on January 2008

Gene transfer using the mature form of VEGF-D reduces neointimal thickening through nitric oxide-dependent mechanism

scientific article

Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo

scientific article

Genome-wide functional analysis reveals central signaling regulators of lymphatic endothelial cell migration and remodeling.

scientific article published on 3 October 2017

Genomic structure and expression of the mouse growth factor receptor related to tyrosine kinases (Ryk).

scientific article published in March 1999

Growth factors regulating lymphatic vessels

scientific article published on 01 January 2000

Growth factors: the journey continues

scientific article published on February 2016

ICAM-1 (CD54): a counter-receptor for Mac-1 (CD11b/CD18)

scientific article

Immunoscintigraphy for detection of lymph node metastases from breast cancer

scientific article published on 01 December 1984

Importance of Wnt signaling in the tumor stroma microenvironment.

scientific article published on September 2008

Increased renal expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 in experimental diabetes

scientific article published on 01 November 1999

Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence.

scientific article published in January 1996

Intestinal-specific activatable Myb initiates colon tumorigenesis in mice.

scientific article published on 24 August 2015

Leukocyte integrin P150,95 (CD11c/CD18) functions as an adhesion molecule binding to a counter-receptor on stimulated endothelium

scientific article published on 01 January 1991

Localization of vascular endothelial growth factor-D in malignant melanoma suggests a role in tumour angiogenesis

scientific article published on 01 February 2001

Lymphangiogenesis and cancer metastasis

scientific article

Lymphangiogenesis and lymphatic vessel remodelling in cancer

scientific article published on March 2014

Lymphangiogenesis in Health and Disease – An Overview

article

Lymphangiogenic growth factor responsiveness is modulated by postnatal lymphatic vessel maturation

scientific article published on August 2006

Lymphatic endothelium: an important interactive surface for malignant cells.

scientific article

Lymphatic vessel density in primary melanomas predicts sentinel lymph node status and risk of metastasis

scientific article published on 01 October 2012

Lymphatic vessels in cancer metastasis: bridging the gaps

scientific article

Lymphovascular and neural regulation of metastasis: shared tumour signalling pathways and novel therapeutic approaches

scientific article

Mammary serum antigen (MSA) levels as a marker for breast cancer: a survey of blood donors and patients with cancer

scientific article published on 01 January 1987

Molecular control of lymphatic metastasis.

scientific article published on January 2008

Molecular pathways for lymphangiogenesis and their role in human disease.

scientific article published on January 2007

Molecular regulation of the VEGF family -- inducers of angiogenesis and lymphangiogenesis.

scientific article

Molecular targeting of lymphatics for therapy.

scientific article published on January 2004

Monoclonal antibodies reactive with mucin expressed in breast cancer

scientific article published on 01 June 1989

Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease

scientific article published on 01 October 1995

Multiple forms of mouse vascular endothelial growth factor-D are generated by RNA splicing and proteolysis

scientific article

Mutagenesis and selection of PDZ domains that bind new protein targets.

scientific article

Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation.

scientific article

Placenta growth factor and vascular endothelial growth factor are co-expressed during early embryonic development

scientific article published in January 1997

Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D

scientific article

Preparation of human vascular endothelial growth factor-D for structural and preclinical therapeutic studies.

scientific article published on 10 January 2012

Proprotein convertases promote processing of VEGF-D, a critical step for binding the angiogenic receptor VEGFR-2

scientific article published on 22 January 2007

Pseudocowpox virus encodes a homolog of vascular endothelial growth factor

scientific article published in January 2003

Purification and biochemical characterisation of a novel breast carcinoma associated mucin-like glycoprotein defined by antibody 3E1.2.

scientific article

Regenerating lizard tails: a new model for investigating lymphangiogenesis

scientific article published on 02 January 2003

Regulation of Adhesion to ICAM-1 by the Cytoplasmic Domain of LFA-1 Integrin β Subunit ⬇️

scientific article published on March 29, 1991

Remodeling of the lymphatic vasculature during mouse mammary gland morphogenesis is mediated via epithelial-derived lymphangiogenic stimuli

scientific article published on 11 October 2012

Renal ischemia-reperfusion increases endothelial VEGFR-2 without increasing VEGF or VEGFR-1 expression

scientific article published on 01 May 2002

Ryk, a receptor regulating Wnt5a-mediated neurogenesis and axon morphogenesis of ventral midbrain dopaminergic neurons

scientific journal article

Signaling for lymphangiogenesis via VEGFR-3 is required for the early events of metastasis.

scientific article published on 17 April 2013

Sox18 induces development of the lymphatic vasculature in mice

scientific journal article

Systematic high-content genome-wide RNAi screens of endothelial cell migration and morphology

scientific article

Targeting lymphangiogenesis to prevent tumour metastasis

scientific article

Targeting tumor stroma

scientific article published on 01 September 2008

The 3T3-L1 fibroblast to adipocyte conversion is accompanied by increased expression of angiopoietin-1, a ligand for tie2.

scientific article published on January 2000

The Angiogenic and Lymphangiogenic Factor Vascular Endothelial Growth Factor-D Exhibits a Paracrine Mode of Action in Cancer

scientific article published on 01 June 2002

The Role of the Tumor Vasculature in the Host Immune Response: Implications for Therapeutic Strategies Targeting the Tumor Microenvironment

scientific article published on 20 December 2016

The VD1 neutralizing antibody to vascular endothelial growth factor-D: binding epitope and relationship to receptor binding

scientific article published on 18 February 2011

The Wnt coreceptor Ryk regulates Wnt/planar cell polarity by modulating the degradation of the core planar cell polarity component Vangl2.

scientific article

The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum

scientific journal article

The Wnt receptor Ryk plays a role in mammalian planar cell polarity signaling

scientific article

The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity

scientific article

The connection between lymphangiogenic signalling and prostaglandin biology: a missing link in the metastatic pathway.

scientific article

The fibrinolysis inhibitor α2-antiplasmin restricts lymphatic remodelling and metastasis in a mouse model of cancer

scientific article published on 11 July 2017

The prognostic value of immunoperoxidase staining with monoclonal antibodies NCRC-11 and 3E1.2 in breast cancer.

scientific article

The propeptides of VEGF-D determine heparin binding, receptor heterodimerization, and effects on tumor biology.

scientific article published on 12 February 2013

The role of tumor lymphangiogenesis in metastatic spread.

scientific article

The specificity of receptor binding by vascular endothelial growth factor-d is different in mouse and man

scientific article (publication date: June 2001)

The vascular endothelial growth factor family: signalling for vascular development.

scientific article

Three-dimensional CRISPR screening reveals epigenetic interaction with anti-angiogenic therapy

scientific article published on 15 July 2021

Tie2 receptor expression and phosphorylation in cultured cells and mouse tissues

scientific article published in March 1997

Tissues in different anatomical sites can sculpt and vary the tumor microenvironment to affect responses to therapy

scientific article published on 19 September 2013

Transfection of cells from patients with leukocyte adhesion deficiency with an integrin beta subunit (CD18) restores lymphocyte function-associated antigen-1 expression and function

scientific article

Tumor location and nature of lymphatic vessels are key determinants of cancer metastasis ⬇️

scientific article published on November 3, 2012

Tumor lymphangiogenesis and metastatic spread-new players begin to emerge.

scientific article

VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues

scientific article published on 01 October 2000

VEGF-D is an X-linked/AP-1 Regulated Putative Onco-angiogen in Human Glioblastoma Multiforme ⬇️

scientific article published on September 1, 2001

VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses

scientific article (publication date: 30 May 2003)

VEGF-D promotes pulmonary oedema in hyperoxic acute lung injury

scientific article published on 29 February 2016

VEGF-D promotes the metastatic spread of tumor cells via the lymphatics

scientific article (publication date: February 2001)

VEGFD regulates blood vascular development by modulating SOX18 activity.

scientific article published on 22 November 2013

Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1

scientific article

Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)

scientific article

Vascular endothelial growth factor D is dispensable for development of the lymphatic system

scientific article

Vascular endothelial growth factor and its receptors in control and diabetic rat eyes

scientific article published on 01 August 1998

Vascular endothelial growth factor-D expression in human atherosclerotic lesions

scientific article published on 01 October 2003

Vascular endothelial growth factor-D over-expressing tumor cells induce differential effects on uterine vasculature in a mouse model of endometrial cancer

scientific article

Vascular endothelial growth factor-D: signaling mechanisms, biology, and clinical relevance ⬇️

scientific article published on July 20, 2012

Vascular endothelial growth factor-d modulates caliber and function of initial lymphatics in the dermis

scientific article published on 25 February 2013

Vascular remodeling in cancer.

scientific article published on 05 August 2013

Vegfd modulates both angiogenesis and lymphangiogenesis during zebrafish embryonic development

scientific article published on 13 January 2017

Viral Vascular Endothelial Growth Factors Vary Extensively in Amino Acid Sequence, Receptor-binding Specificities, and the Ability to Induce Vascular Permeability yet Are Uniformly Active Mitogens

scientific article published in Journal of Biological Chemistry

Viral vascular endothelial growth factor plays a critical role in orf virus infection.

scientific article published on November 2000

Wnt5a induces Ryk-dependent and -independent effects on callosal axon and dendrite growth.

scientific article

Wnt5a regulates midbrain dopaminergic axon growth and guidance

scientific journal article

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