List of works - Paula M Canas

A critical role of the adenosine A2A receptor in extrastriatal neurons in modulating psychomotor activity as revealed by opposite phenotypes of striatum and forebrain A2A receptor knock-outs.

scientific article

Adenosine A1 and A2A receptors differently control synaptic plasticity in the mouse dorsal and ventral hippocampus

scientific article published on 02 August 2019

Adenosine A2A Receptors Control Glutamatergic Synaptic Plasticity in Fast Spiking Interneurons of the Prefrontal Cortex.

scientific article published on 20 March 2018

Adenosine A2A receptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms.

scientific article

Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by beta-amyloid peptides via p38 mitogen-activated protein kinase pathway

scientific article

Adenosine A2A receptors control neuroinflammation and consequent hippocampal neuronal dysfunction.

scientific article

Adenosine A2b receptors control A1 receptor-mediated inhibition of synaptic transmission in the mouse hippocampus

scientific article

Adenosine A₂A receptors in striatal glutamatergic terminals and GABAergic neurons oppositely modulate psychostimulant action and DARPP-32 phosphorylation.

scientific article

Age-Related Changes in the Synaptic Density of Amyloid-β Protein Precursor and Secretases in the Human Cerebral Cortex.

scientific article published on 18 April 2016

Anandamide Effects in a Streptozotocin-Induced Alzheimer's Disease-Like Sporadic Dementia in Rats

scientific article published on 21 September 2018

Blockade of adenosine A(2A) receptors prevents staurosporine-induced apoptosis of rat hippocampal neurons

scientific article published on 26 May 2007

Blockade of adenosine A2A receptors prevents interleukin-1β-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathway

scientific article

Blockade of adenosine A2A receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease

scientific article published on 31 May 2018

Brain Membrane Fractionation: An Ex Vivo Approach to Assess Subsynaptic Protein Localization

scientific article published on 12 May 2017

Caffeine Controls Glutamatergic Synaptic Transmission and Pyramidal Neuron Excitability in Human Neocortex

scientific article

Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress

scientific article

Depression as a Glial-Based Synaptic Dysfunction

scientific article

Different synaptic and subsynaptic localization of adenosine A2A receptors in the hippocampus and striatum of the rat.

scientific article published in January 2005

Enhanced ATP release and CD73-mediated adenosine formation sustain adenosine A2A receptor over-activation in a rat model of Parkinson's disease

scientific article published on 01 August 2019

Enhanced role of adenosine A(2A) receptors in the modulation of LTP in the rat hippocampus upon ageing

scientific article published on 25 May 2011

Erratum: Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory

scientific article published on 24 March 2015

Hyperactivation of D1 and A2A receptors contributes to cognitive dysfunction in Huntington's disease

scientific article

Increased density and synapto-protective effect of adenosine A2A receptors upon sub-chronic restraint stress

scientific article published on 22 June 2006

Key modulatory role of presynaptic adenosine A2A receptors in cortical neurotransmission to the striatal direct pathway.

scientific article

Microglia cytoarchitecture in the brain of adenosine A2A receptor knockout mice: Brain region and sex specificities

scientific article published on 01 November 2019

Mitochondria in Excitatory and Inhibitory Synapses have Similar Susceptibility to Amyloid-β Peptides Modeling Alzheimer's Disease.

scientific article published in September 2017

Modification of adenosine modulation of acetylcholine release in the hippocampus of aged rats

scientific article

Modification upon aging of the density of presynaptic modulation systems in the hippocampus.

scientific article

Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by Convulsions

scientific article published on 01 November 2018

Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory

scientific article

Overexpression of Adenosine A2A Receptors in Rats: Effects on Depression, Locomotion, and Anxiety

scientific article published on 13 June 2014

Predominant loss of glutamatergic terminal markers in a β-amyloid peptide model of Alzheimer's disease.

scientific article published on 9 September 2013

Presymptomatic MPTP Mice Show Neurotrophic S100B/mRAGE Striatal Levels.

scientific article published on 4 February 2016

Spermine improves recognition memory deficit in a rodent model of Huntington's disease

scientific article published on 24 July 2009

Synaptic and memory dysfunction in a β-amyloid model of early Alzheimer's disease depends on increased formation of ATP-derived extracellular adenosine

scientific article published on 05 August 2019

The P2X7 receptor antagonist Brilliant Blue G attenuates contralateral rotations in a rat model of Parkinsonism through a combined control of synaptotoxicity, neurotoxicity and gliosis.

scientific article published on 6 February 2014

The exercise sex gap and the impact of the estrous cycle on exercise performance in mice

scientific article published on 16 July 2018

The interplay between redox signalling and proteostasis in neurodegeneration: In vivo effects of a mitochondria-targeted antioxidant in Huntington's disease mice

scientific article published on 18 November 2019

The role of parkinson's disease-associated receptor GPR37 in the hippocampus: functional interplay with the adenosinergic system.

scientific article published on 21 April 2015

List of works by Paula M Canas

A critical role of the adenosine A2A receptor in extrastriatal neurons in modulating psychomotor activity as revealed by opposite phenotypes of striatum and forebrain A2A receptor knock-outs.

Adenosine A1 and A2A receptors differently control synaptic plasticity in the mouse dorsal and ventral hippocampus

Adenosine A2A Receptors Control Glutamatergic Synaptic Plasticity in Fast Spiking Interneurons of the Prefrontal Cortex.

Adenosine A2A receptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms.

Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by beta-amyloid peptides via p38 mitogen-activated protein kinase pathway

Adenosine A2A receptors control neuroinflammation and consequent hippocampal neuronal dysfunction.

Adenosine A2b receptors control A1 receptor-mediated inhibition of synaptic transmission in the mouse hippocampus

Adenosine A₂A receptors in striatal glutamatergic terminals and GABAergic neurons oppositely modulate psychostimulant action and DARPP-32 phosphorylation.

Age-Related Changes in the Synaptic Density of Amyloid-β Protein Precursor and Secretases in the Human Cerebral Cortex.

Anandamide Effects in a Streptozotocin-Induced Alzheimer's Disease-Like Sporadic Dementia in Rats

Blockade of adenosine A(2A) receptors prevents staurosporine-induced apoptosis of rat hippocampal neurons

Blockade of adenosine A2A receptors prevents interleukin-1β-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathway

Blockade of adenosine A2A receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease

Brain Membrane Fractionation: An Ex Vivo Approach to Assess Subsynaptic Protein Localization

Caffeine Controls Glutamatergic Synaptic Transmission and Pyramidal Neuron Excitability in Human Neocortex

Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress

Depression as a Glial-Based Synaptic Dysfunction

Different synaptic and subsynaptic localization of adenosine A2A receptors in the hippocampus and striatum of the rat.

Enhanced ATP release and CD73-mediated adenosine formation sustain adenosine A2A receptor over-activation in a rat model of Parkinson's disease

Enhanced role of adenosine A(2A) receptors in the modulation of LTP in the rat hippocampus upon ageing

Erratum: Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory

Hyperactivation of D1 and A2A receptors contributes to cognitive dysfunction in Huntington's disease

Increased density and synapto-protective effect of adenosine A2A receptors upon sub-chronic restraint stress

Key modulatory role of presynaptic adenosine A2A receptors in cortical neurotransmission to the striatal direct pathway.

Microglia cytoarchitecture in the brain of adenosine A2A receptor knockout mice: Brain region and sex specificities

Mitochondria in Excitatory and Inhibitory Synapses have Similar Susceptibility to Amyloid-β Peptides Modeling Alzheimer's Disease.

Modification of adenosine modulation of acetylcholine release in the hippocampus of aged rats

Modification upon aging of the density of presynaptic modulation systems in the hippocampus.

Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by Convulsions

Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory

Overexpression of Adenosine A2A Receptors in Rats: Effects on Depression, Locomotion, and Anxiety

Predominant loss of glutamatergic terminal markers in a β-amyloid peptide model of Alzheimer's disease.

Presymptomatic MPTP Mice Show Neurotrophic S100B/mRAGE Striatal Levels.

Spermine improves recognition memory deficit in a rodent model of Huntington's disease

Synaptic and memory dysfunction in a β-amyloid model of early Alzheimer's disease depends on increased formation of ATP-derived extracellular adenosine

The P2X7 receptor antagonist Brilliant Blue G attenuates contralateral rotations in a rat model of Parkinsonism through a combined control of synaptotoxicity, neurotoxicity and gliosis.

The exercise sex gap and the impact of the estrous cycle on exercise performance in mice

The interplay between redox signalling and proteostasis in neurodegeneration: In vivo effects of a mitochondria-targeted antioxidant in Huntington's disease mice

The role of parkinson's disease-associated receptor GPR37 in the hippocampus: functional interplay with the adenosinergic system.