Search filters

List of works by Simon P. Brooks

A Longitudinal Motor Characterisation of the HdhQ111 Mouse Model of Huntington's Disease

scientific article published on 31 May 2016

A Longitudinal Operant Assessment of Cognitive and Behavioural Changes in the HdhQ111 Mouse Model of Huntington's Disease

scientific article published on 04 October 2016

A novel extended sequence learning task (ESLeT) for rodents: validation and the effects of amphetamine, scopolamine and striatal lesions

scientific article published on 20 October 2010

Age-dependent maintenance of motor control and corticostriatal innervation by death receptor 3.

scientific article

Assessment of Motor Coordination and Balance in Mice Using the Rotarod, Elevated Bridge, and Footprint Tests.

scientific article

Behavioural profiles of inbred mouse strains used as transgenic backgrounds. I: motor tests

scientific article published in August 2004

Brain gene expression correlates with changes in behavior in the R6/1 mouse model of Huntington's disease.

scientific article published on 13 August 2007

Cognitive deficits in animal models of basal ganglia disorders.

scientific article

Cognitive training modifies disease symptoms in a mouse model of Huntington's disease

scientific article

Comparison of mHTT Antibodies in Huntington's Disease Mouse Models Reveal Specific Binding Profiles and Steady-State Ubiquitin Levels with Disease Development

scientific article

Corrigendum: Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease.

scientific article published on 28 March 2017

Early onset deficits on the delayed alternation task in the Hdh(Q92) knock-in mouse model of Huntington's disease.

scientific article published on 31 March 2011

Effects of corticosterone on place conditioning to ethanol.

scientific article published in July 2004

Effects of reinforcer sweetness and the D2/D3 antagonist raclopride on progressive ratio operant performance

scientific article published on 01 March 1995

Exercise attenuates neuropathology and has greater benefit on cognitive than motor deficits in the R6/1 Huntington's disease mouse model

scientific article

Gene expression and behaviour in mouse models of HD.

scientific article published on 10 August 2011

Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdhQ111 Model of HD.

scientific article published on 14 December 2015

Identification of novel alternative splicing events in the huntingtin gene and assessment of the functional consequences using structural protein homology modelling.

scientific article

In Vivo MRI Evidence that Neuropathology is Attenuated by Cognitive Enrichment in the Yac128 Huntington's Disease Mouse Model.

scientific article published on July 2015

Light and electron microscopic characterization of the evolution of cellular pathology in HdhQ92 Huntington's disease knock-in mice.

scientific article published on 13 April 2011

Light and electron microscopic characterization of the evolution of cellular pathology in YAC128 Huntington's disease transgenic mice

scientific article

Light and electron microscopic characterization of the evolution of cellular pathology in the Hdh(CAG)150 Huntington's disease knock-in mouse.

scientific article published on 13 April 2011

Light and electron microscopic characterization of the evolution of cellular pathology in the R6/1 Huntington's disease transgenic mice.

scientific article

Longitudinal analyses of operant performance on the serial implicit learning task (SILT) in the YAC128 Huntington's disease mouse line

scientific article

Longitudinal analysis of gene expression and behaviour in the HdhQ150 mouse model of Huntington's disease

scientific article

Longitudinal analysis of the behavioural phenotype in HdhQ92 Huntington's disease knock-in mice

scientific article published on 10 May 2010

Longitudinal analysis of the behavioural phenotype in R6/1 (C57BL/6J) Huntington's disease transgenic mice

scientific article published on 25 January 2011

Longitudinal analysis of the behavioural phenotype in YAC128 (C57BL/6J) Huntington's disease transgenic mice

scientific article published on 10 May 2010

Low alcohol preference among the "high alcohol preference" C57/BL10 mice; factors affecting such preference.

scientific article published in May 2002

Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease

scientific article

Motor actions of eliprodil in the normal and monoamine-depleted mouse: a role in the treatment of Parkinson's disease?

scientific article published on 01 January 1996

Mouse Models of Huntington's Disease

scientific article published on 01 January 2015

Nimodipine prevents the effects of ethanol in tests of memory.

scientific article published in March 2002

Nimodipine prior to alcohol withdrawal prevents memory deficits during the abstinence phase.

scientific article published on 11 September 2008

Operant Analysis of Fronto-striatal Function in Rodents

Optimising Golgi-Cox staining for use with perfusion-fixed brain tissue validated in the zQ175 mouse model of Huntington's disease

scientific article published on 9 October 2015

Practice, progress and future directions for physical therapies in Huntingtons disease

scientific article

Profiles of motor and cognitive impairment in the transgenic rat model of Huntington's disease.

scientific article

Proteomic changes in the brains of Huntington's disease mouse models reflect pathology and implicate mitochondrial changes

scientific article published on 25 January 2011

Rule learning, visuospatial function and motor performance in the Hdh(Q92) knock-in mouse model of Huntington's disease.

scientific article published on 13 May 2009

Selective cognitive impairment in the YAC128 Huntington's disease mouse.

scientific article

Selective extra-dimensional set shifting deficit in a knock-in mouse model of Huntington's disease

scientific journal article

Selective increases in regional brain glucocorticoid: a novel effect of chronic alcohol.

scientific article

Similar striatal gene expression profiles in the striatum of the YAC128 and HdhQ150 mouse models of Huntington's disease are not reflected in mutant Huntingtin inclusion prevalence

scientific article published on 21 December 2015

Social defeat increases alcohol preference of C57BL/10 strain mice; effect prevented by a CCKB antagonist.

scientific article

Striatal lesions in the mouse disrupt acquisition and retention, but not implicit learning, in the SILT procedural motor learning task

scientific article published on 20 September 2007

Subtle but progressive cognitive deficits in the female tgHD hemizygote rat as demonstrated by operant SILT performance.

scientific article

Tests to assess motor phenotype in mice: a user's guide

scientific article

The utilisation of operant delayed matching and non-matching to position for probing cognitive flexibility and working memory in mouse models of Huntington's disease

scientific article published on 27 August 2015

Paulina is supported by:

About Paulina

Help