Search filters

List of works by McHardy M. Smith

A disubstituted succinamide is a potent sodium channel blocker with efficacy in a rat pain model

scientific article published on August 2004

A high-throughput assay for evaluating state dependence and subtype selectivity of Cav2 calcium channel inhibitors.

scientific article

A novel benzazepinone sodium channel blocker with oral efficacy in a rat model of neuropathic pain

scientific article published on 05 April 2013

A potent and selective indole N-type calcium channel (Ca(v)2.2) blocker for the treatment of pain

scientific article published on 21 November 2010

Aminopiperidine sulfonamide Cav2.2 channel inhibitors for the treatment of chronic pain

scientific article published on 12 November 2012

Assembly intermediates of the mouse muscle nicotinic acetylcholine receptor in stably transfected fibroblasts

scientific article

Benzazepinone Nav1.7 blockers: Potential treatments for neuropathic pain

article

Characterization of the solubilized charybdotoxin receptor from bovine aortic smooth muscle

scientific article published on 01 November 1991

Discovery of a novel class of benzazepinone Nav1.7 blockers: Potential treatments for neuropathic pain

article

Discovery of a novel class of biphenyl pyrazole sodium channel blockers for treatment of neuropathic pain

scientific article published on 14 October 2010

Discovery of a novel class of isoxazoline voltage gated sodium channel blockers

scientific article published on 6 August 2009

Discovery of isoxazole voltage gated sodium channel blockers for treatment of chronic pain

scientific article

Discovery of potent and use-dependent sodium channel blockers for treatment of chronic pain

article

Drug-resistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin.

scientific article published on December 2000

Functional assay of voltage-gated sodium channels using membrane potential-sensitive dyes.

scientific article published on June 2004

Improved Cav2.2 Channel Inhibitors through a gem-Dimethylsulfone Bioisostere Replacement of a Labile Sulfonamide

scientific article

Nodulisporic acids D-F: structure, biological activities, and biogenetic relationships.

scientific article published in September 2004

Novel cyclopentane dicarboxamide sodium channel blockers as a potential treatment for chronic pain

scientific article

Substituted biaryl oxazoles, imidazoles, and thiazoles as sodium channel blockers

article

Substituted biaryl pyrazoles as sodium channel blockers

article

Synthesis and SAR of 1,2-trans-(1-hydroxy-3-phenylprop-1-yl)cyclopentane carboxamide derivatives, a new class of sodium channel blockers

scientific article

The genetics of ivermectin resistance in Caenorhabditis elegans

scientific article

Type III omega-agatoxins: a family of probes for similar binding sites on L- and N-type calcium channels.

scientific article published in May 1994