List of works - Craig McFarlane

Body fat partitioning does not explain the interethnic variation in insulin sensitivity among Asian ethnicity: the Singapore adults metabolism study.

scientific article

G protein-coupled receptor kinase 2 regulates mitochondrial bioenergetics and impairs myostatin-mediated autophagy in muscle cells

scientific article published on 03 July 2019

Human myostatin negatively regulates human myoblast growth and differentiation

scientific article

Identification of atrogin-1-targeted proteins during the myostatin-induced skeletal muscle wasting

scientific article published on 06 June 2012

Inactivation of PPARβ/δ adversely affects satellite cells and reduces postnatal myogenesis.

scientific article published on 28 April 2015

Inhibition of myostatin protects against diet-induced obesity by enhancing fatty acid oxidation and promoting a brown adipose phenotype in mice

scientific article published on 17 September 2011

Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy.

scientific article

Irisin treatment improves healing of dystrophic skeletal muscle.

scientific article published on 6 October 2017

Lack of Smad3 signaling leads to impaired skeletal muscle regeneration

scientific article published on 24 April 2012

Lack of myostatin reduces MyoD induced myogenic potential of primary muscle fibroblasts

scientific article published on 01 November 2014

Loss of Parkin impairs mitochondrial function and leads to muscle atrophy

scientific article published on 21 March 2018

Mechanism of myostatin action during satellite cell activation and muscle wasting. ⬇️

2007 doctoral thesis by Craig Desmond McFarlane at University of Waikato

Mega roles of microRNAs in regulation of skeletal muscle health and disease

scientific article

Mitochondrial oxidative capacity and NAD+ biosynthesis are reduced in human sarcopenia across ethnicities

scientific article published on 20 December 2019

Modulation of reactive oxygen species in skeletal muscle by myostatin is mediated through NF‐κB ⬇️

scientific article published on August 16, 2011

Muscle-specific microRNA1 (miR1) targets heat shock protein 70 (HSP70) during dexamethasone-mediated atrophy.

scientific article published on 6 January 2013

Myostatin augments muscle-specific ring finger protein-1 expression through an NF-kB independent mechanism in SMAD3 null muscle

scientific article

Myostatin induces cachexia by activating the ubiquitin proteolytic system through an NF-kappaB-independent, FoxO1-dependent mechanism

scientific article published in November 2006

Myostatin inhibits rhabdomyosarcoma cell proliferation through an Rb-independent pathway.

scientific article published on January 2004

Myostatin promotes the wasting of human myoblast cultures through promoting ubiquitin-proteasome pathway-mediated loss of sarcomeric proteins

scientific article published on 7 September 2011

Myostatin signals through Pax7 to regulate satellite cell self-renewal

scientific article published on 22 September 2007

Myostatin signals through miR-34a to regulate Fndc5 expression and browning of white adipocytes.

scientific article published on 14 June 2016

Myostatin-deficient mice exhibit reduced insulin resistance through activating the AMP-activated protein kinase signalling pathway.

scientific article

Myostatin-null mice exhibit delayed skin wound healing through the blockade of transforming growth factor-β signaling by decorin

scientific article published on 25 January 2012

Myostatin: expanding horizons

scientific article (publication date: August 2015)

Narciclasine attenuates diet-induced obesity by promoting oxidative metabolism in skeletal muscle.

scientific article

Negative auto-regulation of myostatin expression is mediated by Smad3 and microRNA-27.

scientific article published on 31 January 2014

Proteolytic processing of myostatin is auto-regulated during myogenesis

scientific article published in July 2005

Smad3 signaling is required for satellite cell function and myogenic differentiation of myoblasts ⬇️

scientific article published on April 19, 2011

The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis

scientific article

List of works by Craig McFarlane

Body fat partitioning does not explain the interethnic variation in insulin sensitivity among Asian ethnicity: the Singapore adults metabolism study.

G protein-coupled receptor kinase 2 regulates mitochondrial bioenergetics and impairs myostatin-mediated autophagy in muscle cells

Human myostatin negatively regulates human myoblast growth and differentiation

Identification of atrogin-1-targeted proteins during the myostatin-induced skeletal muscle wasting

Inactivation of PPARβ/δ adversely affects satellite cells and reduces postnatal myogenesis.

Inhibition of myostatin protects against diet-induced obesity by enhancing fatty acid oxidation and promoting a brown adipose phenotype in mice

Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy.

Irisin treatment improves healing of dystrophic skeletal muscle.

Lack of Smad3 signaling leads to impaired skeletal muscle regeneration

Lack of myostatin reduces MyoD induced myogenic potential of primary muscle fibroblasts

Loss of Parkin impairs mitochondrial function and leads to muscle atrophy

Mechanism of myostatin action during satellite cell activation and muscle wasting. ⬇️

Mega roles of microRNAs in regulation of skeletal muscle health and disease

Mitochondrial oxidative capacity and NAD+ biosynthesis are reduced in human sarcopenia across ethnicities

Modulation of reactive oxygen species in skeletal muscle by myostatin is mediated through NF‐κB ⬇️

Muscle-specific microRNA1 (miR1) targets heat shock protein 70 (HSP70) during dexamethasone-mediated atrophy.

Myostatin augments muscle-specific ring finger protein-1 expression through an NF-kB independent mechanism in SMAD3 null muscle

Myostatin induces cachexia by activating the ubiquitin proteolytic system through an NF-kappaB-independent, FoxO1-dependent mechanism

Myostatin inhibits rhabdomyosarcoma cell proliferation through an Rb-independent pathway.

Myostatin promotes the wasting of human myoblast cultures through promoting ubiquitin-proteasome pathway-mediated loss of sarcomeric proteins

Myostatin signals through Pax7 to regulate satellite cell self-renewal

Myostatin signals through miR-34a to regulate Fndc5 expression and browning of white adipocytes.

Myostatin-deficient mice exhibit reduced insulin resistance through activating the AMP-activated protein kinase signalling pathway.

Myostatin-null mice exhibit delayed skin wound healing through the blockade of transforming growth factor-β signaling by decorin

Myostatin: expanding horizons

Narciclasine attenuates diet-induced obesity by promoting oxidative metabolism in skeletal muscle.

Negative auto-regulation of myostatin expression is mediated by Smad3 and microRNA-27.

Proteolytic processing of myostatin is auto-regulated during myogenesis

Smad3 signaling is required for satellite cell function and myogenic differentiation of myoblasts ⬇️

The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis