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List of works by Nancy M. Bonini

A drosophila model for amyotrophic lateral sclerosis reveals motor neuron damage by human SOD1.

scientific article published on 2 July 2008

A new role for microRNA pathways: modulation of degeneration induced by pathogenic human disease proteins.

scientific article published on 15 December 2006

A novel Drosophila model of nerve injury reveals an essential role of Nmnat in maintaining axonal integrity

scientific article

A tribute to Seymour Benzer, 1921--2007.

scientific article

A yeast functional screen predicts new candidate ALS disease genes

scientific article published on 7 November 2011

ATXN2 trinucleotide repeat length correlates with risk of ALS.

scientific article

Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity

scientific article published in Nature Communications

Age-dependent patterns of microRNA RISC loading

scientific article

Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

scientific article

An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis

scientific article

An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease

scientific article published on 28 September 2020

Applications of the Drosophila retina to human disease modeling

scientific article

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS

scientific article

Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients

scientific article

Ataxin-3 suppresses polyglutamine neurodegeneration in Drosophila by a ubiquitin-associated mechanism

scientific article published in April 2005

Author Correction: Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity

scientific article published in Nature Communications

Author Correction: An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease

scientific article published on 08 October 2020

Axon degeneration and regeneration: insights from Drosophila models of nerve injury.

scientific article published on 23 July 2012

Axon injury and regeneration in the adult Drosophila

scientific article

Biochemical and pathological characterization of Lrrk2.

scientific article published on February 2006

Changes in the Transcriptome of Human Astrocytes Accompanying Oxidative Stress-Induced Senescence

scientific article published on 31 August 2016

Chaperoning brain degeneration

scientific article

Convergence of heat shock protein 90 with ubiquitin in filamentous alpha-synuclein inclusions of alpha-synucleinopathies

scientific article

DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function

scientific article

Defining Genetic Factors That Modulate Intergenerational CAG Repeat Instability in Drosophila melanogaster ⬇️

scientific article published on November 1, 2010

Design and implementation of in vivo imaging of neural injury responses in the adult Drosophila wing

scientific article

Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease

scientific article published in September 2005

Drosophila Ref1/ALYREF regulates transcription and toxicity associated with ALS/FTD disease etiologies

scientific article published on 29 April 2019

Drosophila as a genetic tool to define vertebrate pathway players

scientific article

Drosophila as a model for human neurodegenerative disease

scientific article

Drosophila as an In Vivo Model for Human Neurodegenerative Disease

scientific article

Dual functions of the Drosophila eyes absent gene in the eye and embryo.

scientific article

Dynamic neural and glial responses of a head-specific model for traumatic brain injury in Drosophila

scientific article published on 01 July 2020

Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease.

scientific article published on 5 March 2018

Early decisions in Drosophila eye morphogenesis.

scientific article

Editorial overview: Molecular & genetic basis of disease

scientific article published in May 2017

En Masse Analysis of Genetic Modifiers Informs Players and Processes in ALS

scientific article published on 23 November 2018

Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis

scientific article

Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila

scientific article published in June 1998

Fruit flies on the front line: the translational impact of Drosophila

scientific article published on March 2016

Functional analysis of an eye enhancer of the Drosophila eyes absent gene: differential regulation by eye specification genes

scientific article published in May 2000

GGGGCC microsatellite RNA is neuritically localized, induces branching defects, and perturbs transport granule function

scientific article published on 9 December 2015

Genes and pathways affected by CAG-repeat RNA-based toxicity in Drosophila

scientific article published on 20 September 2011

Genome-wide screen for modifiers of ataxin-3 neurodegeneration in Drosophila

scientific article (publication date: October 2007)

Glial AP1 is activated with aging and accelerated by traumatic brain injury

scientific article published on 08 July 2021

Hope on the (fruit) fly: the Drosophila wing paradigm of axon injury

scientific article

Hosting neurotoxicity in polyglutamine disease

scientific article published in December 2006

Hsp104 suppresses polyglutamine-induced degeneration post onset in a drosophila MJD/SCA3 model.

scientific article

Human neurodegenerative disease modeling using Drosophila

scientific article published on 10 April 2003

Impact of age-associated increase in 2'-O-methylation of miRNAs on aging and neurodegeneration in Drosophila

scientific article (publication date: 2014)

Inducing different severities of traumatic brain injury in Drosophila using a piezoelectric actuator

scientific article published on 04 December 2020

Loss of miR-34 in Drosophila dysregulates protein translation and protein turnover in the aging brain

scientific article published on 15 February 2022

Maintaining the brain: insight into human neurodegeneration from Drosophila melanogaster mutants

scientific article

Mechanisms of Suppression of {alpha}-Synuclein Neurotoxicity by Geldanamycin in Drosophila.

scientific article published on 18 November 2004

Methods to detect patterns of cell death in Drosophila

scientific article

MiR-34 inhibits polycomb repressive complex 2 to modulate chaperone expression and promote healthy brain aging

scientific article published in Nature Communications

MicroRNA pathways modulate polyglutamine-induced neurodegeneration

scientific article published in October 2006

MicroRNAs and neurodegeneration: role and impact

scientific article published on 28 September 2012

Model organisms reveal insight into human neurodegenerative disease: ataxin-2 intermediate-length polyglutamine expansions are a risk factor for ALS.

scientific article published on 10 June 2011

Modeling Human Trinucleotide Repeat Diseases in Drosophila

scientific article published on January 1, 2011

Modeling human neurodegenerative diseases in Drosophila: on a wing and a prayer.

scientific article

Multiple roles of the eyes absent gene in Drosophila

scientific article published in April 1998

Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging

scholarly article

Pharmacological prevention of Parkinson disease in Drosophila.

scientific article published in November 2002

Poly(ADP-ribose) Engages the TDP-43 Nuclear-Localization Sequence to Regulate Granulo-Filamentous Aggregation

scientific article published on 17 December 2018

Poly-A binding protein-1 localization to a subset of TDP-43 inclusions in amyotrophic lateral sclerosis occurs more frequently in patients harboring an expansion in C9orf72

scientific article

PolyQ repeat expansions in ATXN2 associated with ALS are CAA interrupted repeats

scientific article (publication date: 29 March 2011)

Polyglutamine genes interact to modulate the severity and progression of neurodegeneration in Drosophila

scientific article

Preventing Ataxin-3 protein cleavage mitigates degeneration in a Drosophila model of SCA3.

scientific article published on 25 September 2009

Protein interacting with C kinase (PICK1) is a suppressor of spinocerebellar ataxia 3-associated neurodegeneration in Drosophila

scientific article published on 23 September 2011

Publisher Correction: Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease.

scientific article published on 19 March 2018

RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways

scientific article

RNA toxicity is a component of ataxin-3 degeneration in Drosophila

scientific article

Regulation of ciliary motility by membrane potential inParamecium: A role for cyclic AMP

scientific article published on 01 January 1986

Roles of trinucleotide-repeat RNA in neurological disease and degeneration.

scientific article published on 14 April 2010

Silencing polyglutamine degeneration with RNAi

scientific article

Snaring the function of alpha-synuclein

scientific article

Stores to Die For

scientific article published on 01 October 2001

Suppression of polyglutamine toxicity by the yeast Sup35 prion domain in Drosophila

scientific article published on 23 October 2007

Surviving Drosophila eye development

scientific article published in January 1997

TDP-43 Promotes Neurodegeneration by Impairing Chromatin Remodeling.

scientific article published on 9 November 2017

TDP-43 a protein central to amyotrophic lateral sclerosis is destabilized by Tankyrase-1/2

scientific article published on 14 May 2020

The Sustained Impact of Model Organisms-in Genetics and Epigenetics

scientific article published on January 2017

The exonuclease Nibbler regulates age-associated traits and modulates piRNA length in Drosophila

scientific article published on 6 March 2015

The exoribonuclease Nibbler controls 3' end processing of microRNAs in Drosophila.

scientific article published on 3 November 2011

The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye.

scientific article

The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila

scientific article published on 15 February 2012

Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models

scientific article

Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD

scientific article published on 20 May 2019

Toxicity of pathogenic ataxin-2 in Drosophila shows dependence on a pure CAG repeat sequence

scientific article published on 01 September 2021

Transcription factor YY1 functions as a PcG protein in vivo

scientific article

Triplet repeat-derived siRNAs enhance RNA-mediated toxicity in a Drosophila model for myotonic dystrophy

scientific article

eIF4B and eIF4H mediate GR production from expanded G4C2 in a Drosophila model for C9orf72-associated ALS

scientific article published on 25 April 2019

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