List of works - Sally Freeman

"Chelatable iron pool": inositol 1,2,3-trisphosphate fulfils the conditions required to be a safe cellular iron ligand.

scientific article published on 2 September 2008

AMT (3-(2-aminopropyl)indole) and 5-IT (5-(2-aminopropyl)indole): an analytical challenge and implications for forensic analysis

scientific article

Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.

scientific article published in January 2005

Analytical characterisation of the routes by thermolytic decarboxylation from tryptophan to tryptamine using ketone catalysts, resulting in tetrahydro-beta-carboline formation.

scientific article

Analytical chemistry of synthetic routes to psychoactive tryptamines. Part II. Characterisation of the Speeter and Anthony synthetic route to N,N-dialkylated tryptamines using GC-EI-ITMS, ESI-TQ-MS-MS and NMR.

scientific article

Arylethylamine psychotropic recreational drugs: a chemical perspective.

scientific article

Characterisation of a proposed internet synthesis of N,N-dimethyltryptamine using liquid chromatography/electrospray ionisation tandem mass spectrometry.

scientific article published on 23 June 2009

Characterization of the synthesis of N,N-dimethyltryptamine by reductive amination using gas chromatography ion trap mass spectrometry.

scientific article published on July 2010

Cloning, overexpression and mechanistic studies of carboxyphosphonoenolpyruvate mutase from Streptomyces hygroscopicus ⬇️

scientific article (publication date: 15 October 1992)

Design, Synthesis and Evaluation of Oxazaborine Inhibitors of the NLRP3 Inflammasome

scientific article published on 13 January 2018

Design, synthesis and enzymatic evaluation of 6-bridged imidazolyluracil derivatives as inhibitors of human thymidine phosphorylase.

scientific article

Detection of apoptosis by PET/CT with the diethyl ester of [¹⁸F]ML-10 and fluorescence imaging with a dansyl analogue

scientific article

Difluoro analogue of UCS15A triggers activation of exogenously expressed c-Src in HCT 116 human colorectal carcinoma cells

scientific article published on October 2007

Discovery of potent 4-aminoquinoline hydrazone inhibitors of NRH:quinoneoxidoreductase-2 (NQO2)

scientific article published on 27 August 2019

Effects of 1,1-Dichloroethene and of Some of Its Metabolites on the Functional Viability of Mouse Hepatocytes

scientific article published in August 1993

Exciplex and excimer molecular probes: detection of conformational flip in a myo-inositol chair.

scientific article published on 9 April 2008

Fluorescent probe for detection of bacteria: conformational trigger upon bacterial reduction of an azo bridge

scientific article published in 2012

Fluorescent probe: complexation of Fe3+ with the myo-inositol 1,2,3-trisphosphate motif.

scientific article published on 29 September 2008

Halogenated solvent interactions with N,N-dimethyltryptamine: formation of quaternary ammonium salts and their artificially induced rearrangements during analysis.

scientific article published in May 2008

Identification of a novel class of inhibitor of human and Escherichia coli thymidine phosphorylase by in silico screening.

scientific article published in November 2003

In Vitro Evaluation of Third Generation PAMAM Dendrimer Conjugates.

scientific article published on 4 October 2017

In silico screening and biological evaluation of inhibitors of Src-SH3 domain interaction with a proline-rich ligand

scientific article

In vitro evaluation of dendrimer prodrugs for oral drug delivery

scientific article published in May 2007

Influence of cranberry juice on attachment of Escherichia coli to glass

scientific article published in February 2000

Inhibiting the NLRP3 Inflammasome

scientific article published on 25 November 2020

Inhibition of quorum sensing and biofilm formation in Vibrio harveyi by 4-fluoro-DPD; a novel potent inhibitor of signalling

scientific article published in May 2014

Inositol polyphosphate-mediated iron transport in Pseudomonas aeruginosa

scientific article published in March 1999

Is metabolism an important arbiter of anticancer activity of ether lipids? Metabolism of SRI 62-834 and hexadecylphosphocholine by [31P]-NMR spectroscopy and comparison of their cytotoxicities with those of their metabolites

scientific article published on January 1992

N,N-Dimethyltryptamine and dichloromethane: rearrangement of quaternary ammonium salt product during GC-EI and CI-MS-MS analysis.

scientific article

PAMAM dendrimers for the delivery of the antibacterial Triclosan

scientific article published in January 2008

Phosphonate biosynthesis: isolation of the enzyme responsible for the formation of a carbon-phosphorus bond.

scientific article

Potential tumor-selective nitroimidazolylmethyluracil prodrug derivatives: inhibitors of the angiogenic enzyme thymidine phosphorylase.

scientific article

Stereochemistry at phosphorus of the reaction catalyzed by myo-inositol monophosphatase.

scientific article

Stereochemistry of phospho group transfer catalyzed by a mutant alkaline phosphatase

scientific article published on 28 June 1988

Structure–activity relationship of 2,4,5-trioxoimidazolidines as inhibitors of thymidine phosphorylase

scientific article published in April 2011

Synthesis and antibacterial activities of enamine derivatives of dehydroacetic acid

scientific article published on 13 November 2017

Synthesis and assessment of first-generation polyamidoamine dendrimer prodrugs to enhance the cellular permeability of P-gp substrates.

scientific article published on 14 March 2007

Synthesis and bioluminescence-inducing properties of autoinducer (S)-4,5-dihydroxypentane-2,3-dione and its enantiomer

scientific article published on 19 February 2010

Synthesis and enzymatic evaluation of pyridinium-substituted uracil derivatives as novel inhibitors of thymidine phosphorylase.

scientific article published in March 2002

Synthesis and iron binding studies of myo-inositol 1,2,3-trisphosphate and (±)-myo-inositol 1,2-bisphosphate, and iron binding studies of all myo-inositol tetrakisphosphates

scientific article published in February 1996

The naphyrone story: The alpha or beta-naphthyl isomer?

scientific article

Thymidine phosphorylase from Escherichia coli: Tight-binding inhibitors as enzyme active-site titrants

scientific article published in January 2006

Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors

scientific article published in June 2008

myo-Inositol esters of indomethacin as COX-2 inhibitors

scientific article published in July 2012

List of works by Sally Freeman

"Chelatable iron pool": inositol 1,2,3-trisphosphate fulfils the conditions required to be a safe cellular iron ligand.

AMT (3-(2-aminopropyl)indole) and 5-IT (5-(2-aminopropyl)indole): an analytical challenge and implications for forensic analysis

Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.

Analytical characterisation of the routes by thermolytic decarboxylation from tryptophan to tryptamine using ketone catalysts, resulting in tetrahydro-beta-carboline formation.

Analytical chemistry of synthetic routes to psychoactive tryptamines. Part II. Characterisation of the Speeter and Anthony synthetic route to N,N-dialkylated tryptamines using GC-EI-ITMS, ESI-TQ-MS-MS and NMR.

Arylethylamine psychotropic recreational drugs: a chemical perspective.

Characterisation of a proposed internet synthesis of N,N-dimethyltryptamine using liquid chromatography/electrospray ionisation tandem mass spectrometry.

Characterization of the synthesis of N,N-dimethyltryptamine by reductive amination using gas chromatography ion trap mass spectrometry.

Cloning, overexpression and mechanistic studies of carboxyphosphonoenolpyruvate mutase from Streptomyces hygroscopicus ⬇️

Design, Synthesis and Evaluation of Oxazaborine Inhibitors of the NLRP3 Inflammasome

Design, synthesis and enzymatic evaluation of 6-bridged imidazolyluracil derivatives as inhibitors of human thymidine phosphorylase.

Detection of apoptosis by PET/CT with the diethyl ester of [¹⁸F]ML-10 and fluorescence imaging with a dansyl analogue

Difluoro analogue of UCS15A triggers activation of exogenously expressed c-Src in HCT 116 human colorectal carcinoma cells

Discovery of potent 4-aminoquinoline hydrazone inhibitors of NRH:quinoneoxidoreductase-2 (NQO2)

Effects of 1,1-Dichloroethene and of Some of Its Metabolites on the Functional Viability of Mouse Hepatocytes

Exciplex and excimer molecular probes: detection of conformational flip in a myo-inositol chair.

Fluorescent probe for detection of bacteria: conformational trigger upon bacterial reduction of an azo bridge

Fluorescent probe: complexation of Fe3+ with the myo-inositol 1,2,3-trisphosphate motif.

Halogenated solvent interactions with N,N-dimethyltryptamine: formation of quaternary ammonium salts and their artificially induced rearrangements during analysis.

Identification of a novel class of inhibitor of human and Escherichia coli thymidine phosphorylase by in silico screening.

In Vitro Evaluation of Third Generation PAMAM Dendrimer Conjugates.

In silico screening and biological evaluation of inhibitors of Src-SH3 domain interaction with a proline-rich ligand

In vitro evaluation of dendrimer prodrugs for oral drug delivery

Influence of cranberry juice on attachment of Escherichia coli to glass

Inhibiting the NLRP3 Inflammasome

Inhibition of quorum sensing and biofilm formation in Vibrio harveyi by 4-fluoro-DPD; a novel potent inhibitor of signalling

Inositol polyphosphate-mediated iron transport in Pseudomonas aeruginosa

Is metabolism an important arbiter of anticancer activity of ether lipids? Metabolism of SRI 62-834 and hexadecylphosphocholine by [31P]-NMR spectroscopy and comparison of their cytotoxicities with those of their metabolites

N,N-Dimethyltryptamine and dichloromethane: rearrangement of quaternary ammonium salt product during GC-EI and CI-MS-MS analysis.

PAMAM dendrimers for the delivery of the antibacterial Triclosan

Phosphonate biosynthesis: isolation of the enzyme responsible for the formation of a carbon-phosphorus bond.

Potential tumor-selective nitroimidazolylmethyluracil prodrug derivatives: inhibitors of the angiogenic enzyme thymidine phosphorylase.

Stereochemistry at phosphorus of the reaction catalyzed by myo-inositol monophosphatase.

Stereochemistry of phospho group transfer catalyzed by a mutant alkaline phosphatase

Structure–activity relationship of 2,4,5-trioxoimidazolidines as inhibitors of thymidine phosphorylase

Synthesis and antibacterial activities of enamine derivatives of dehydroacetic acid

Synthesis and assessment of first-generation polyamidoamine dendrimer prodrugs to enhance the cellular permeability of P-gp substrates.

Synthesis and bioluminescence-inducing properties of autoinducer (S)-4,5-dihydroxypentane-2,3-dione and its enantiomer

Synthesis and enzymatic evaluation of pyridinium-substituted uracil derivatives as novel inhibitors of thymidine phosphorylase.

Synthesis and iron binding studies of myo-inositol 1,2,3-trisphosphate and (±)-myo-inositol 1,2-bisphosphate, and iron binding studies of all myo-inositol tetrakisphosphates

The naphyrone story: The alpha or beta-naphthyl isomer?

Thymidine phosphorylase from Escherichia coli: Tight-binding inhibitors as enzyme active-site titrants

Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors

myo-Inositol esters of indomethacin as COX-2 inhibitors