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List of works by Noel F. Lowndes

53BP1: function and mechanisms of focal recruitment

scientific article published on August 2009

A Cell-cycle-regulated trans-Factor, DSC1, Controls Expression of DNA Synthesis Genes in Yeast

article

A novel Rad24 checkpoint protein complex closely related to replication factor C.

scientific article

A role for Saccharomyces cerevisiae histone H2A in DNA repair.

scientific article

A role for the p53 tumour suppressor in regulating the balance between homologous recombination and non-homologous end joining

scientific article published on September 2016

ATR activates the S-M checkpoint during unperturbed growth to ensure sufficient replication prior to mitotic onset

scientific article published on 21 November 2013

ATR-ATRIP kinase complex triggers activation of the Fanconi anemia DNA repair pathway

scientific article

An investigation into 53BP1 complex formation

scientific article published on January 2007

Analysis of Biphenyl-Type Inhibitors Targeting the Eg5 α4/α6 Allosteric Pocket

Analysis of novel missense ATR mutations reveals new splicing defects underlying Seckel syndrome

scientific article published on 24 September 2018

Autofluorescent proteins

scientific article published on January 2008

BRCA1 Is Required for Maintenance of Phospho-Chk1 and G2/M Arrest during DNA Cross-Link Repair in DT40 Cells

scientific article

Binding specificity of the G1/S transcriptional regulators in budding yeast

scientific article

Chaperoning the Cln3 cyclin prevents promiscuous activation of start.

scientific article

Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex

scientific article (publication date: September 2001)

Chromatin assembly and signalling the end of DNA repair requires acetylation of histone H3 on lysine 56.

scientific article published on January 2010

Chromatin modulation and the DNA damage response

scientific article published on 30 June 2006

Co-mutation of histone H2AX S139A with Y142A rescues Y142A-induced ionising radiation sensitivity.

scientific article published on 29 September 2012

Control of DNA synthesis genes in fission yeast by the cell-cycle gene cdclO+ ⬇️

scientific article published on January 30, 1992

Correction for Travesa et al., "Repression of G1/S Transcription Is Mediated via Interaction of the GTB Motifs of Nrm1 and Whi5 with Swi6"

scientific article published on 28 July 2017

DNA repair: From molecular mechanism to human disease

scientific article published on 01 August 2006

DNA repair: the importance of phosphorylating histone H2AX.

scientific article

DUN1 defines one branch downstream of RAD53 for transcription and DNA damage repair in Saccharomyces cerevisiae

scientific article published on 01 November 2000

Differential Response of Mouse Thymic Epithelial Cell Types to Ionizing Radiation-Induced DNA Damage

scientific article

Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain

scientific article published in February 2007

Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation.

scientific article

Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activity

scientific article

Enhanced protein detection using a trapping mode on a hybrid quadrupole linear ion trap (Q-Trap).

scientific article published in August 2009

Eukaryotic DNA damage checkpoint activation in response to double-strand breaks

scientific article

Genetic dissection of vertebrate 53BP1: a major role in non-homologous end joining of DNA double strand breaks

scientific article published on 27 April 2006

Genetic evidence for single-strand lesions initiating Nbs1-dependent homologous recombination in diversification of Ig v in chicken B lymphocytes

scientific article

Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation

scientific article published on 2 May 2006

Human and mouse homologs of Schizosaccharomyces pombe rad1(+) and Saccharomyces cerevisiae RAD17: linkage to checkpoint control and mammalian meiosis

scientific article

Hypoxia enhances the radioresistance of mouse mesenchymal stromal cells.

scientific article published in August 2014

MRN and the race to the break

scientific article published on 28 October 2009

Mesenchymal stromal cells: radio-resistant members of the bone marrow

scientific article

Mobility and distribution of replication protein A in living cells using fluorescence correlation spectroscopy

scientific article

Modification of histones by sugar β-N-acetylglucosamine (GlcNAc) occurs on multiple residues, including histone H3 serine 10, and is cell cycle-regulated

scientific article

Multiple approaches to study S. cerevisiae Rad9, a prototypical checkpoint protein

scientific article published in January 2006

Multiple facets of the DNA damage response contribute to the radioresistance of mouse mesenchymal stromal cell lines

scientific article published on January 2013

Parallel pathways of cell cycle-regulated gene expression

scientific article published on March 1, 1992

Phenotypic and functional heterogeneity of human intermediate monocytes based on HLA-DR expression.

scientific article published on 5 March 2018

RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activation ⬇️

scientific article published on May 1, 1998

Rational design and validation of a Tip60 histone acetyltransferase inhibitor.

scientific article

Recruitment of lysine demethylase 2A to DNA double strand breaks and its interaction with 53BP1 ensures genome stability

scientific article published on 23 March 2018

Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor

scientific article

Repression of G1/S transcription is mediated via interaction of the GTB motifs of Nrm1 and Whi5 with Swi6.

scientific article

Sensing and responding to DNA damage.

scientific article

Site-specific phosphorylation of the DNA damage response mediator rad9 by cyclin-dependent kinases regulates activation of checkpoint kinase 1

scientific article

The MRN complex

scientific article

The MRN complex: coordinating and mediating the response to broken chromosomes

scientific article

The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins

scientific article (publication date: May 2014)

The Transcription Factor Hif-1 Enhances the Radio-Resistance of Mouse MSCs.

scientific article published on 26 April 2018

The budding yeast Rad9 checkpoint complex: chaperone proteins are required for its function

scientific article

The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage ⬇️

scientific article published on October 1, 1998

The interplay between BRCA1 and 53BP1 influences death, aging, senescence and cancer ⬇️

article by Noel F. Lowndes et al published 5 October 2010 in DNA Repair

The switch from survival responses to apoptosis after chromosomal breaks

scientific article published in August 2004

Transcriptional response of Candida parapsilosis following exposure to farnesol

scientific article published in July 2007

Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage

scientific article

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