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List of works by Simona Coppola

A mutation in PAK3 with a dual molecular effect deregulates the RAS/MAPK pathway and drives an X-linked syndromic phenotype.

scientific article published on 19 February 2014

A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function

scientific article published on 10 October 2019

Activating MRAS mutations cause Noonan syndrome associated with hypertrophic cardiomyopathy

article

Anti-apoptotic effect of HIV protease inhibitors via direct inhibition of calpain.

scientific article published in October 2003

Autocrine role of angiopoietins during megakaryocytic differentiation

scientific article

Colocalization of the VEGF-R2 and the common IL-3/GM-CSF receptor beta chain to lipid rafts leads to enhanced p38 activation.

scientific article

Different basal NAD levels determine opposite effects of poly(ADP-ribosyl)polymerase inhibitors on H2O2-induced apoptosis.

scientific article published on December 1995

Dominant Noonan syndrome-causing LZTR1 mutations specifically affect the kelch domain substrate-recognition surface and enhance RAS-MAPK signaling

scientific article published on 01 March 2019

Enforced expression of KDR receptor promotes proliferation, survival and megakaryocytic differentiation of TF1 progenitor cell line.

scientific article published on January 2006

Functional Dysregulation of CDC42 Causes Diverse Developmental Phenotypes

scientific article published on 17 January 2018

GSH depletion enhances adenoviral bax-induced apoptosis in lung cancer cells.

scientific article published on April 2004

Glutathione depletion causes cytochrome c release even in the absence of cell commitment to apoptosis

scientific article published in November 1999

H2O2-induced block of glycolysis as an active ADP-ribosylation reaction protecting cells from apoptosis

scientific article published on 01 November 2000

Identification of the hemangioblast in postnatal life

scientific article published on 01 November 2002

Magnetic fields increase cell survival by inhibiting apoptosis via modulation of Ca2+ influx.

scientific article published on January 1999

Multiple mechanisms for hydrogen peroxide-induced apoptosis.

scientific article published in August 2009

Non-oxidative loss of glutathione in apoptosis via GSH extrusion.

scientific article published on November 1995

Oxidative Bax dimerization promotes its translocation to mitochondria independently of apoptosis.

scientific article published on 21 June 2005

Possible involvement of poly(ADP-ribosyl) polymerase in triggering stress-induced apoptosis.

scientific article published on June 1994

Protease Involvement in Fodrin Cleavage and Phosphatidylserine Exposure in Apoptosis

scientific article published in Journal of Biological Chemistry

Redox Modulation of the Apoptogenic Activity of Thapsigargin

scientific article published on 01 March 2007

Rescue of cells from apoptosis by inhibition of active GSH extrusion.

scientific article

SHOC2 subcellular shuttling requires the KEKE motif-rich region and N-terminal leucine-rich repeat domain and impacts on ERK signalling

scientific article published on 27 July 2016

Sequential phases of Ca2+ alterations in pre-apoptotic cells.

scientific article published in December 2007

The Italian National Centre for Rare Diseases: where research and public health translate into action

scientific article

The cleavage mode of apoptotic nuclear vesiculation is related to plasma membrane blebbing and depends on actin reorganization.

scientific article published on December 2006

The increase in H2O2-induced apoptosis by ADP-ribosylation inhibitors is related to cell blebbing.

scientific article published on December 1995

White cell apoptosis in packed red cells

scientific article published on 01 November 1998

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