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List of works by Maria João Gama

Association of A313 G polymorphism (GSTP1*B) in the glutathione-S-transferase P1 gene with sporadic Parkinson's disease

scientific article

Cholesterol 24S-Hydroxylase Overexpression Inhibits the Liver X Receptor (LXR) Pathway by Activating Small Guanosine Triphosphate-Binding Proteins (sGTPases) in Neuronal Cells.

scientific article published on 2 August 2014

Chromatin-modifying agents increase transcription of CYP46A1, a key player in brain cholesterol elimination

scientific article published on January 2010

Erratum to: Tauroursodeoxycholic Acid Protects Against Mitochondrial Dysfunction and Cell Death via Mitophagy in Human Neuroblastoma Cells

scientific article published on 01 October 2017

GSTpi expression in MPTP-induced dopaminergic neurodegeneration of C57BL/6 mouse midbrain and striatum

scientific article

Glutathione S-transferase pi mediates MPTP-induced c-Jun N-terminal kinase activation in the nigrostriatal pathway

scientific article

Glutathione S-transferase pi regulates UV-induced JNK signaling in SH-SY5Y neuroblastoma cells

scientific article published on 13 January 2009

Histone deacetylase inhibition decreases cholesterol levels in neuronal cells by modulating key genes in cholesterol synthesis, uptake and efflux

scientific article

Inflammatory signalling pathways involved in astroglial activation by unconjugated bilirubin

scientific article published on 10 February 2006

Marked change in the balance between CYP27A1 and CYP46A1 mediated elimination of cholesterol during differentiation of human neuronal cells.

scientific article

Neuronal cholesterol metabolism increases dendritic outgrowth and synaptic markers via a concerted action of GGTase-I and Trk.

scientific article published on 05 August 2016

Neuronal differentiation alters the ratio of Sp transcription factors recruited to the CYP46A1 promoter ⬇️

scientific article published on November 28, 2011

Novel insights into the antioxidant role of tauroursodeoxycholic acid in experimental models of Parkinson's disease

scientific article published on 2 June 2017

Nrf2 activation by tauroursodeoxycholic acid in experimental models of Parkinson's disease

scientific article

Okadaic acid inhibits the trichostatin A-mediated increase of human CYP46A1 neuronal expression in a ERK1/2-Sp3-dependent pathway.

scientific article

Oxidative Stress and Antioxidants in Neurological Diseases: Is There Still Hope?

scientific article published on April 2016

S-Glutathionylation of Keap1: a new role for glutathione S-transferase pi in neuronal protection.

scientific article

Sp proteins play a critical role in histone deacetylase inhibitor-mediated derepression of CYP46A1 gene transcription.

scientific article

Tauroursodeoxycholic Acid Improves Motor Symptoms in a Mouse Model of Parkinson's Disease

article

Tauroursodeoxycholic Acid Protects Against Mitochondrial Dysfunction and Cell Death via Mitophagy in Human Neuroblastoma Cells

scientific article published on 3 October 2016

Tauroursodeoxycholic acid prevents MPTP-induced dopaminergic cell death in a mouse model of Parkinson's disease.

scientific article

Transcriptional regulation of the human CYP46A1 brain-specific expression by Sp transcription factors.

scientific article published on 28 April 2008

Ubiquitin-proteasome system impairment and MPTP-induced oxidative stress in the brain of C57BL/6 wild-type and GSTP knockout mice

scientific article

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