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List of works by Gene S. Tan

A carboxy-terminal trimerization domain stabilizes conformational epitopes on the stalk domain of soluble recombinant hemagglutinin substrates

scientific article

A pan-H1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo

scientific article

A virus-like particle that elicits cross-reactive antibodies to the conserved stem of influenza virus hemagglutinin.

scientific article

Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice

scientific article published on 10 October 2017

Anti-HA Glycoforms Drive B Cell Affinity Selection and Determine Influenza Vaccine Efficacy

scientific article

Antibodies Elicited by an NS1-Based Vaccine Protect Mice against Zika Virus

article

Assessment of influenza virus hemagglutinin stalk-based immunity in ferrets.

scientific article

Attenuation of rabies virulence: takeover by the cytoplasmic domain of its envelope protein.

scientific article published on 19 January 2010

Author Correction: Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection

scientific article published on 16 June 2020

Both Neutralizing and Non-Neutralizing Human H7N9 Influenza Vaccine-Induced Monoclonal Antibodies Confer Protection

scientific article published on June 2016

Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo

scientific article

Broadly protective monoclonal antibodies against H3 influenza viruses following sequential immunization with different hemagglutinins

scientific article published in February 2010

Broadly protective murine monoclonal antibodies against influenza B virus target highly conserved neuraminidase epitopes.

scientific article

Broadly-Reactive Neutralizing and Non-neutralizing Antibodies Directed against the H7 Influenza Virus Hemagglutinin Reveal Divergent Mechanisms of Protection

scientific article

Characterization of a broadly neutralizing monoclonal antibody that targets the fusion domain of group 2 influenza A virus hemagglutinin

scientific article

Cryo-electron Microscopy Structures of Chimeric Hemagglutinin Displayed on a Universal Influenza Vaccine Candidate.

scientific article published on 22 March 2016

Direct administration in the respiratory tract improves efficacy of broadly neutralizing anti-influenza virus monoclonal antibodies.

scientific article

Divergent H7 immunogens offer protection from H7N9 virus challenge.

scientific article

Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus

scientific article published on 03 October 2016

Guanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity

scientific article

Hemagglutinin Stalk- and Neuraminidase-Specific Monoclonal Antibodies Protect against Lethal H10N8 Influenza Virus Infection in Mice

scientific article

Hemagglutinin Stalk-Reactive Antibodies Are Boosted following Sequential Infection with Seasonal and Pandemic H1N1 Influenza Virus in Mice

scientific article

Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses

scientific article

Hemagglutinin stalk-based universal vaccine constructs protect against group 2 influenza A viruses.

scientific article published on 31 July 2013

Human Monoclonal Antibodies Potently Neutralize Zika Virus and Select for Escape Mutations on the Lateral Ridge of the Envelope Protein

scientific article published on 28 June 2019

Human antibodies targeting Zika virus NS1 provide protection against disease in a mouse model

scientific article published in Nature Communications

In vivo bioluminescent imaging of influenza a virus infection and characterization of novel cross-protective monoclonal antibodies

scientific article

Influenza A Viruses Expressing Intra- or Intergroup Chimeric Hemagglutinins

scientific article published on 13 January 2016

Influenza viruses expressing chimeric hemagglutinins: globular head and stalk domains derived from different subtypes

scientific article

Innate Immune Response to Influenza Virus at Single-Cell Resolution in Human Epithelial Cells Revealed Paracrine Induction of Interferon Lambda 1

scientific article published on 30 September 2019

Intravenous inoculation of a bat-associated rabies virus causes lethal encephalopathy in mice through invasion of the brain via neurosecretory hypothalamic fibers

scientific article published on 19 June 2009

Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection

scientific article published on 21 May 2020

Monoclonal Antibodies with Neutralizing Activity and Fc-Effector Functions against the Machupo Virus Glycoprotein

scientific article published on 14 February 2020

Neutralizing Monoclonal Antibodies against the Gn and the Gc of the Andes Virus Glycoprotein Spike Complex Protect from Virus Challenge in a Preclinical Hamster Model

scientific article published on 24 March 2020

Optimal activation of Fc-mediated effector functions by influenza virus hemagglutinin antibodies requires two points of contact

scientific article published on 19 September 2016

PPEY motif within the rabies virus (RV) matrix protein is essential for efficient virion release and RV pathogenicity

scientific article published on 30 July 2008

Preexisting human antibodies neutralize recently emerged H7N9 influenza strains.

scientific article

Rabies virus nucleoprotein as a carrier for foreign antigens.

scholarly article

Replication-deficient rabies virus-based vaccines are safe and immunogenic in mice and nonhuman primates.

scientific article

Strong cellular and humoral anti-HIV Env immune responses induced by a heterologous rhabdoviral prime–boost approach

article

Synthetic Toll-Like Receptor 4 (TLR4) and TLR7 Ligands Work Additively via MyD88 To Induce Protective Antiviral Immunity in Mice

scientific article

The application of reverse genetics technology in the study of rabies virus (RV) pathogenesis and for the development of novel RV vaccines.

scientific article

Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes

scientific article

Vaccination with adjuvanted recombinant neuraminidase induces broad heterologous, but not heterosubtypic, cross-protection against influenza virus infection in mice.

scientific article published on 10 March 2015

Vaccination with soluble headless hemagglutinin protects mice from challenge with divergent influenza viruses

scientific article published on 28 May 2015

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