List of works by Soterios A Kyrtopoulos

A composite framework for the statistical analysis of epidemiological DNA methylation data with the Infinium Human Methylation 450K BeadChip

scientific article

A life course approach to explore the biological embedding of socioeconomic position and social mobility through circulating inflammatory markers

scientific article published on 27 April 2016

A multi-omics approach to investigate the inflammatory response to life course socioeconomic position

scientific article published on 02 September 2020

Aberrant DNA damage response pathways may predict the outcome of platinum chemotherapy in ovarian cancer

scientific article

Adduct levels from benzo[a]pyrenediol epoxide: Relative formation to histidine in serum albumin and to deoxyguanosine in DNA in vitro and in vivo in mice measured by LC/MS-MS methods

scientific article published on 26 September 2014

Alcohol-related cancer risk: a toxicokinetic hypothesis.

scientific article published on March 1995

Association between low-grade inflammation and Breast cancer and B-cell Myeloma and Non-Hodgkin Lymphoma: findings from two prospective cohorts

scientific article published in Scientific Reports

Association between transcriptional activity, local chromatin structure, and the efficiencies of both subpathways of nucleotide excision repair of melphalan adducts.

scientific article published on 5 May 2009

Association of Prenatal Exposure to Persistent Organic Pollutants with Obesity and Cardiometabolic Traits in Early Childhood: The Rhea Mother-Child Cohort (Crete, Greece)

scientific article

Associations Between Genome-wide Gene Expression and Ambient Nitrogen Oxides

scientific article published on 30 January 2017

Benzo[a]pyrene-enhanced mutagenesis by man-made mineral fibres in the lung of lamda-lacI transgenic rats.

scientific article published in March 2006

Benzo[a]pyrene-induced cell cycle arrest in HepG2 cells is associated with delayed induction of mitotic instability.

scientific article published on 19 July 2014

Biological marks of early-life socioeconomic experience is detected in the adult inflammatory transcriptome

scientific article published on 09 December 2016

Biomarkers and molecular epidemiology--present state and future trends: concluding remarks

scientific article published on 27 June 2006

Biomarkers in children and adults—Introduction and overview

scientific article published on 25 May 2007

Biomarkers of genotoxicity of urban air pollution. Overview and descriptive data from a molecular epidemiology study on populations exposed to moderate-to-low levels of polycyclic aromatic hydrocarbons: the AULIS project.

scientific article

Biomonitoring human exposure to environmental carcinogenic chemicals.

scientific article

Birth weight, head circumference, and prenatal exposure to acrylamide from maternal diet: the European prospective mother-child study (NewGeneris).

scientific article published on 23 September 2012

Blood erythrocyte concentrations of cadmium and lead and the risk of B-cell non-Hodgkin's lymphoma and multiple myeloma: a nested case-control study

scientific article

Blood-based omic profiling supports female susceptibility to tobacco smoke-induced cardiovascular diseases ⬇️

scientific article published on 22 February 2017

Bulky dna adducts in cord blood, maternal fruit-and-vegetable consumption, and birth weight in a European mother-child study (NewGeneris).

scientific article published on 23 July 2013

Chromatin structure, transcriptional activity and DNA repair efficiency affect the outcome of chemotherapy in multiple myeloma

scientific article

Coexposure to ethanol with N-nitrosodimethylamine or 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone during lactation of rats: marked increase in O(6)-methylguanine-DNA adducts in maternal mammary gland and in suckling lung and kidney.

scientific article published in December 2000

Comparative dosimetry of O6-methylguanine in humans and rodents treated with procarbazine.

scientific article published in August 1994

Comparative study of mutagenesis by O6-methylguanine in the human Ha-ras oncogene in E. coli and in vitro

scientific article

Comparative study of the formation and repair of O6-methylguanine in humans and rodents treated with dacarbazine

scientific article published on 01 April 1996

Compounds in food

scientific article published on 01 May 2008

DNA adducts in humans after exposure to methylating agents

scientific article published on 01 September 1998

DNA adducts, mutant frequencies and mutation spectra in lambda lacZ transgenic mice treated with N-nitrosodimethylamine.

scientific article published in May 1998

DNA damage and mutagenesis induced by procarbazine in lambda lacZ transgenic mice: evidence that bone marrow mutations do not arise primarily through miscoding by O6-methylguanine.

scientific article published in November 1997

DNA methylation and exposure to ambient air pollution in two prospective cohorts.

scientific article published on 23 August 2017

Detection and quantitation of benzo[a]pyrene-derived DNA adducts in mouse liver by liquid chromatography-tandem mass spectrometry: comparison with 32P-postlabeling

scientific article published on 01 June 2006

Development and Validation of a New, Sensitive Immunochemical Assay for O6-Methylguanine in DNA and Its Application in a Population Study

scientific article published on 16 November 2010

Development and validation of a PCR-based assay for the selection of patients more likely to benefit from therapeutic treatment with alkylating drugs.

scientific article

Development and validation of a new assay for O6-alkylguanine-DNA-alkyltransferase based on the use of an oligonucleotide substrate, and its application to the measurement of DNA repair activity in extracts of biopsy samples of human urinary bladder

scientific article

Differential effects of procarbazine and methylnitrosourea on the accumulation of O6-methylguanine and the depletion and recovery of O6-alkylguanine-DNA alkyltransferase in rat tissues

scientific article published on 01 August 1994

Dosimetry of O6-methylguanine in rat DNA after low-dose, chronic exposure to N-nitrosodimethylamine (NDMA). Implications for the mechanism of NDMA hepatocarcinogenesis.

scientific article

Dynamics of smoking-induced genome-wide methylation changes with time since smoking cessation

scientific article

EXPOsOMICS: final policy workshop and stakeholder consultation

scientific article published on 15 February 2018

Elimination of heparin interference during microarray processing of fresh and biobank-archived blood samples.

scientific article published on 17 April 2014

Environmental genotoxins in children and adults: Introduction and overview

scientific article published on 11 July 2006

Environmental genotoxins in children and adults: concluding remarks

scientific article published on 11 July 2006

Environmental, dietary, maternal, and fetal predictors of bulky DNA adducts in cord blood: a European mother-child study (NewGeneris) ⬇️

scientific article

Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study

scientific article

Erratum: "Environmental, Dietary, Maternal, and Fetal Predictors of Bulky DNA Adducts in Cord Blood: A European Mother-Child Study (NewGeneris)".

scientific article published in January 2016

Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis

scientific article published on 13 September 2017

Exploring the nature of prediagnostic blood transcriptome markers of chronic lymphocytic leukemia by assessing their overlap with the transcriptome at the clinical stage

scientific article

Genotoxic effects of asbestos in humans

scientific article published in September 2004

Identification of Sex-Specific Transcriptome Responses to Polychlorinated Biphenyls (PCBs)

scientific article published in Scientific Reports

Immunological monitoring in workers occupationally exposed to asbestos

scientific article published on 01 January 2005

Immunomodulatory effects of mineral fibres in occupationally exposed workers

scientific article published on 01 September 2004

Impact of phase I or phase II enzyme polymorphisms on lymphocyte DNA adducts in subjects exposed to urban air pollution and environmental tobacco smoke.

scientific article published on April 2004

In utero exposure to compounds with dioxin-like activity and birth outcomes.

scientific article published in March 2014

In vivo formation and repair of O6-methylguanine in human leukocyte DNA after intravenous exposure to dacarbazine.

scientific article published in February 1991

Induction of sister chromatid exchanges and chromosome aberrations in cultured mammalian cells by N-nitrosocimetidine

scientific article published on 01 October 1981

Induction of somatic mutations but not methylated DNA adducts in lambdalacZ transgenic mice by dichlorvos.

scientific article published in November 1999

Interactions between CYP1A1 polymorphisms and exposure to environmental tobacco smoke in the modulation of lymphocyte bulky DNA adducts and chromosomal aberrations.

scientific article published on 30 September 2004

Intra- and intercellular variations in the repair efficiency of O6-methylguanine, and their contribution to kinetic complexity.

scientific article

Kinetic studies with phosphotransacetylase.

scientific article

Kinetic studies with phosphotransacetylase. 3. The acylation of phosphate ions by acetyl coenzyme A.

scientific article published in August 1972

Kinetic studies with phosphotransacetylase. II. The acetylation of arsenate by acetyl coenzyme A

scientific article published on 01 May 1972

Kinetic studies with phosphotransacetylase. IV. Inhibition by products.

scientific article published in August 1972

Kinetic studies with phosphotransacetylase. V. The mechanism of activation by univalent cations.

scientific article published in September 1973

Making sense of OMICS data in population-based environmental health studies

scientific article

Maternal diet during pregnancy and micronuclei frequency in peripheral blood T lymphocytes in mothers and newborns (Rhea cohort, Crete).

scientific article published on 21 September 2016

Melphalan-induced DNA damage in vitro as a predictor for clinical outcome in multiple myeloma

scientific article published on 01 November 2007

Methyl bromide causes DNA methylation in rats and mice but fails to induce somatic mutations in lambda lacZ transgenic mice.

scientific article published in January 1999

MicroRNA profile for health risk assessment: Environmental exposure to persistent organic pollutants strongly affects the human blood microRNA machinery.

scientific article published on 23 August 2017

Micronuclei in cord blood lymphocytes and associations with biomarkers of exposure to carcinogens and hormonally active factors, gene polymorphisms, and gene expression: the NewGeneris cohort ⬇️

scientific article

Molecular epidemiological approaches to the study of the genotoxic effects of urban air pollution.

scientific article

Multinucleate cells (MNC) as sensitive semiquantitative biomarkers of the toxic effect after experimental fibrous dust and cigarette smoke inhalation by rats

scientific article published on 01 August 2005

Mutagenesis by O6 meG residues within codon 12 of the human Ha-ras proto-oncogene in monkey cells.

scientific article published in September 1992

Mutagenesis by asbestos in the lung of lambda-lacI transgenic rats.

scientific article

Mutagenesis by man-made mineral fibres in the lung of rats.

scientific article published in March 2006

Mutagenic and clastogenic effects of organic extracts from the Athenian drinking water

scientific article published in April 1983

NewGeneris: a European study on maternal diet during pregnancy and child health

scientific article published on 01 January 2009

O6-Alkylguanine-DNA alkyltransferase: influence on susceptibility to the genetic effects of alkylating agents

scientific article published on 01 December 1998

O6-Methylguanine-DNA transmethylase activity in extracts of human gastric mucosa.

scientific article

Omics for prediction of environmental health effects: Blood leukocyte-based cross-omic profiling reliably predicts diseases associated with tobacco smoking ⬇️

scientific article published on 3 February 2016

Performance in omics analyses of blood samples in long-term storage: opportunities for the exploitation of existing biobanks in environmental health research

scientific article published on 5 February 2013

Persistent organic pollutants in early pregnancy and risk of gestational diabetes mellitus

scientific article published on 12 October 2016

Personal exposures to PM(2.5) and polycyclic aromatic hydrocarbons and their relationship to environmental tobacco smoke at two locations in Greece.

scientific article published on May 2001

Polar, functionalized guanine-O6 derivatives resistant to repair by O6-alkylguanine-DNA alkyltransferase: implications for the design of DNA-modifying drugs.

scientific article published on 3 February 2006

Policy recommendations and cost implications for a more sustainable framework for European human biomonitoring surveys

scientific article published on 16 December 2014

Prediagnostic transcriptomic markers of Chronic lymphocytic leukemia reveal perturbations 10 years before diagnosis

scientific article

Preferential in vivo DNA repair of melphalan-induced damage in human genes is greatly affected by the local chromatin structure.

scientific article

Progress in high-throughput assays of MGMT and APE1 activities in cell extracts

scientific article published on 17 May 2012

Progressive changes in chromatin structure and DNA damage response signals in bone marrow and peripheral blood during myelomagenesis

scientific article published on 3 October 2013

Rapid formation of carcinogenic N-nitrosamines in aqueous alkaline solutions ⬇️

scientific article published on May 1, 1977

Studies in gastric carcinogenesis. II. Absence of elevated concentrations of N-nitroso compounds in the gastric juice of Greek hypochlorhydric individuals.

scientific article published in August 1985

Studies in gastric carcinogenesis. III. The kinetics of nitrosation of gastric-juice components in vitro and their implications for the in vivo formation of N-nitroso compounds in normal and in hypochlorhydric populations.

scientific article published in August 1985

Studies in gastric carcinogenesis. IV. O6-methylguanine and its repair in normal and atrophic biopsy specimens of human gastric mucosa. Correlation of O6-alkylguanine-DNA alkyltransferase activities in gastric mucosa and circulating lymphocytes.

scientific article published in March 1990

Studies in gastric carcinogenesis. V. The effects of ascorbic acid on N-nitroso compound formation in human gastric juice in vivo and in vitro.

scientific article published in August 1991

Survey of air pollution in Cotonou, Benin--air monitoring and biomarkers.

scientific article published on April 2006

Tea and coffee consumption in relation to DNA methylation in four European cohorts.

scientific article published in August 2017

The effect of dietary estimates calculated using food frequency questionnaires on micronuclei formation in European pregnant women: a NewGeneris study

scientific article published on 8 October 2014

The exposome in practice: Design of the EXPOsOMICS project.

scientific article published on 19 August 2016

The formation and repair of O6-methylguanine in rat liver nucleolar DNA after dimethylnitrosamine administration studied by radioimmunoassay

scientific article published on 01 October 1981

The repair of melphalan-induced DNA adducts in the transcribed strand of active genes is subject to a strong polarity effect

scientific article

The use of radioimmunoassay to study the formation and disappearance of O6-methylguanine in mouse liver satellite and main-band DNA following dimethylnitrosamine administration

scientific article published on 01 January 1980

Time-series analysis of gene expression profiles induced by nitrosamides and nitrosamines elucidates modes of action underlying their genotoxicity in human colon cells.

scientific article published on 19 September 2011

Toxicity, mutation frequency and mutation spectrum induced by dacarbazine in CHO cells expressing different levels of O(6)-methylguanine-DNA methyltransferase

scientific article

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

scientific article

Transplacental exposure to carcinogens and risks to children: evidence from biomarker studies and the utility of omic profiling

scientific article published on 11 March 2019

Validation of biomarkers for the study of environmental carcinogens: a review

scientific article published on August 2008

Workshop on processing of DNA damage

scientific article published on 01 December 1996

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