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List of works by Federica Cossu

A NMR and computational study of Smac mimics targeting both the BIR2 and BIR3 domains in XIAP protein.

scientific article

Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2

scientific article

Dimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part II: Structural and biological characterization

scientific article

Kinetic and structural evidences on human prolidase pathological mutants suggest strategies for enzyme functional rescue

scientific article

NF023 binding to XIAP-BIR1: searching drugs for regulation of the NF-κB pathway

scientific article

Novel neurofibromatosis type 2 mutation presenting with status epilepticus

scientific article published on 01 March 2014

Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy.

scientific article

Recognition of Smac-mimetic compounds by the BIR domain of cIAP1

scientific article

Structural Insight into Inhibitor of Apoptosis Proteins Recognition by a Potent Divalent Smac-Mimetic

scientific article

Structural bases of the altered catalytic properties of a pathogenic variant of apoptosis inducing factor

scientific article

Structural basis for bivalent Smac-mimetics recognition in the IAP protein family

scientific article

Structure-based design and molecular profiling of Smac-mimetics selective for cellular IAPs

scientific article published on 16 August 2018

TREX1 C-terminal frameshift mutations in the systemic variant of retinal vasculopathy with cerebral leukodystrophy

scientific article published on 12 September 2014

Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo[5.3.0]alkane smac mimetics. Structure, activity, and recognition principles

scientific article

The activator of apoptosis Smac-DIABLO acts as a tetramer in solution

scientific article published on February 2015

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