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List of works by Sara Hägg

A Frailty Index for UK Biobank Participants

scientific article published on 01 March 2019

A Geroscience approach for Parkinson's Disease: conceptual framework and design of PROPAG-AGEING project

scientific article published on 29 December 2020

A decade of epigenetic change in aging twins: Genetic and environmental contributions to longitudinal DNA methylation

scientific article published on 24 July 2020

A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia

scientific article published on 14 March 2018

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study

scientific article

Age, Frailty, and Comorbidity as Prognostic Factors for Short-Term Outcomes in Patients With Coronavirus Disease 2019 in Geriatric Care

scientific article published on 14 August 2020

Age- and sex-specific causal effects of adiposity on cardiovascular risk factors

scientific article published on 23 February 2015

An epigenome-wide association study meta-analysis of educational attainment.

scientific article

Apolipoprotein E DNA methylation and late-life disease

scientific article published on 2 March 2018

Association between genetically predicted telomere length and facial skin aging in the UK Biobank: a Mendelian randomization study

scientific article published on 08 October 2020

Association of telomere length with general cognitive trajectories: a meta-analysis of four prospective cohort studies

scientific article published on 02 June 2018

Author Correction: Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk

scientific article published on 01 March 2020

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

scientific article published on 01 May 2019

Biological Age Predictors.

scientific article

Blood levels of dual-specificity phosphatase-1 independently predict risk for post-operative morbidities causing prolonged hospitalization after coronary artery bypass grafting

scientific article published on 17 March 2011

Can markers of biological age predict dependency in old age?

scientific article published on 21 January 2019

Carotid plaque age is a feature of plaque stability inversely related to levels of plasma insulin

scientific article (publication date: 7 April 2011)

Childhood Adoption and Mental Health in Adulthood: The Role of Gene-Environment Correlations and Interactions in the UK Biobank

scientific article published on 31 October 2019

Circulating antioxidants and Alzheimer disease prevention: a Mendelian randomization study

scientific article published on 01 January 2019

Circulating insulin-like growth factors and Alzheimer disease: A mendelian randomization study.

scientific article published on 27 December 2017

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

scientific article published on 7 June 2021

Comprehensive longitudinal study of epigenetic mutations in aging

scientific article published on 09 December 2019

DNA METHYLATION: CAUSE OR CONSEQUENCE OF AGING?

scholarly article in Innovation in Aging, vol. 3, Suppl 1, November 2019

DNA Methylation and All-Cause Mortality in Middle-Aged and Elderly Danish Twins

scientific article published on 8 February 2018

DNA methylation outlier burden, health, and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936

scientific article published on 26 March 2020

DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

scientific article published in June 2021

DNA mismatch repair gene MSH6 implicated in determining age at natural menopause

scientific article published on 19 December 2013

Dominant Genetic Variation and Missing Heritability for Human Complex Traits: Insights from Twin versus Genome-wide Common SNP Models

scientific article

Drivers of Frailty from Adulthood into Old Age: Results from a 27-year Longitudinal Population-Based Study in Sweden

scientific article published on 29 April 2020

Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

scientific article

Epigenome-wide association study of level and change in cognitive abilities from midlife through late life

scientific article published on 21 April 2021

Evidence of a causal relationship between adiponectin levels and insulin sensitivity: a Mendelian randomization study

scientific article

Exploring the Causal Pathway From Telomere Length to Coronary Heart Disease: A Network Mendelian Randomization Study

scientific article published on 17 May 2017

F8CHILDHOOD ADOPTION AND MENTAL HEALTH IN ADULTHOOD: GENE-ENVIRONMENT INTERPLAY AND CROSS-TRAIT GENETIC OVERLAP WITH AFFECTIVE TRAITS IN UK BIOBANK

scientific article published in 2019

Frailty index as a predictor of all-cause and cause-specific mortality in a Swedish population-based cohort.

scientific article published on 19 December 2017

Frailty trajectories in three longitudinal studies of aging: Is the level or the rate of change more predictive of mortality?

scientific article published on 01 November 2021

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

scientific article published in Nature Communications

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

article

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

scientific article published on 21 June 2013

Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity

scientific article

Genetic and Environmental Contributions to the Covariation Between Cardiometabolic Traits

scientific article published on 18 April 2018

Genetic meta-analysis identifies 9 novel loci and functional pathways for Alzheimers disease risk

Genetic susceptibility to cardiovascular disease and risk of dementia.

scientific article published on 30 May 2017

Genetically-predicted life-long lowering of low-density lipoprotein cholesterol is associated with decreased frailty: A Mendelian randomization study in UK biobank

scientific article published on 09 July 2019

Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length

scientific article published on 27 February 2020

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

article

Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging

scientific article

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk

scholarly article by Iris E Jansen et al published March 2019 in Nature Genetics

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

Habitual coffee consumption and cognitive function: a Mendelian randomization meta-analysis in up to 415,530 participants.

scientific article

Human aging DNA methylation signatures are conserved but accelerated in cultured fibroblasts

scientific article published on 12 June 2019

Identification of seven loci affecting mean telomere length and their association with disease

scientific article published on April 2013

Implementing a method for studying longitudinal DNA methylation variability in association with age

scientific article published on 02 October 2018

Inactivation of the budding yeast cohesin loader Scc2 alters gene expression both globally and in response to a single DNA double strand break

scientific article published on January 2014

LONGITUDINAL TRAJECTORIES OF EPIGENETIC CLOCKS IN HUMANS AND EFFECTS OF MEDICATION USE

scholarly article in Innovation in Aging, vol. 3, Suppl 1, November 2019

Large-scale non-targeted metabolomic profiling in three human population-based studies

Leukocyte Telomere Length and All-Cause Mortality: A Between-Within Twin Study With Time-Dependent Effects Using Generalized Survival Models

scientific article published on 01 October 2018

Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers

scientific article

Longitudinal changes in the genetic and environmental influences on the epigenetic clocks across old age: Evidence from two twin cohorts

scientific article published on 28 January 2019

Longitudinal decline of leukocyte telomere length in old age and the association with sex and genetic risk

scientific article published on 07 July 2016

Longitudinal trajectories, correlations and mortality associations of nine biological ages across 20-years follow-up

scientific article published on 11 February 2020

Marital status, telomere length and cardiovascular disease risk in a Swedish prospective cohort

scientific article published on 14 November 2019

Methylation status of VTRNA2-1 / nc886 is stable across populations, monozygotic twin pairs and in majority of tissues

scientific article published in September 2022

Multi-organ expression profiling uncovers a gene module in coronary artery disease involving transendothelial migration of leukocytes and LIM domain binding 2: the Stockholm Atherosclerosis Gene Expression (STAGE) study

scientific article

Neuroticism as a Predictor of Frailty in Old Age: A Genetically Informative Approach

scientific article published on 01 November 2019

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

Plasma cholesterol-induced lesion networks activated before regression of early, mature, and advanced atherosclerosis

scientific article

Polyunsaturated fatty acids and risk of Alzheimer's disease: a Mendelian randomization study

scientific article published on 01 November 2019

Positive bias for European men in applications for faculty position at Karolinska Institutet

article

Profiles of histidine-rich glycoprotein associate with age and risk of all-cause mortality

scientific article published on 31 July 2020

Relative deprivation and mortality--a longitudinal study in a Swedish population of 4.7 million, 1990-2006.

scientific article

Replicating associations between DNA methylation and body mass index in a longitudinal sample of older twins

scientific article published on 04 December 2019

Serum selenium in relation to measures of glucose metabolism and incidence of Type 2 diabetes in an older Swedish population.

scientific article

Short telomere length is associated with impaired cognitive performance in European ancestry cohorts.

scientific article

Short-term and long-term case-fatality rates for myocardial infarction and ischaemic stroke by socioeconomic position and sex: a population-based cohort study in Sweden, 1990-1994 and 2005-2009

scientific article published on 04 July 2019

Should we invest in biological age predictors to treat colorectal cancer in older adults?

scientific article published on 08 November 2019

Smoking does not accelerate leucocyte telomere attrition: a meta-analysis of 18 longitudinal cohorts

scientific article published on 05 June 2019

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

scientific article published on 29 May 2018

Telomere Length Dynamics and Atherosclerotic Disease

scientific article published in February 2018

Telomere Length Shortening and Alzheimer Disease--A Mendelian Randomization Study

scientific article published on October 2015

Telomere Length Shortening in Alzheimer's Disease: Procedures for a Causal Investigation Using Single Nucleotide Polymorphisms in a Mendelian Randomization Study

scientific article published in January 2018

Telomere Length and All-Cause Mortality: A Meta-analysis

scientific article published on 22 September 2018

Telomere length and cardiovascular disease risk

scientific article published on 01 May 2019

Telomere length in circulating leukocytes is associated with lung function and disease.

scientific article published on 5 December 2013

The association of individual changes in stressful life events and telomere length over time in twins aged 50 years and above

scientific article published on 14 May 2020

The frailty index is a predictor of cause-specific mortality independent of familial effects from midlife onwards: a large cohort study

scientific article published on 15 May 2019

The impact of low-frequency and rare variants on lipid levels

scientific article published on 11 May 2015

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

scientific article (publication date: 2013)

Tracking the Epigenetic Clock Across the Human Life Course: A Meta-analysis of Longitudinal Cohort Data

scientific article published on 01 January 2019

Variation in genes in the endothelin pathway and endothelium-dependent and endothelium-independent vasodilation in an elderly population

article

Vitamin D and cognitive function: A Mendelian randomisation study

scientific article published on 16 October 2017

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