List of works - Niels Eijkelkamp

A role for G protein-coupled receptor kinase 2 in mechanical allodynia

scientific article published on 01 March 2007

A role for Piezo2 in EPAC1-dependent mechanical allodynia.

scientific article

Amyloid Proteins and Peripheral Neuropathy

scientific article published on 26 June 2020

Balancing GRK2 and EPAC1 levels prevents and relieves chronic pain.

scientific article

CD8+ T Cells and Endogenous IL-10 Are Required for Resolution of Chemotherapy-Induced Neuropathic Pain.

scientific article published on October 2016

Critical role for Epac1 in inflammatory pain controlled by GRK2-mediated phosphorylation of Epac1.

scientific article published on 29 February 2016

First-trimester placental vascular development in multiparous women differs from that in nulliparous women

scientific article published on 12 January 2017

G protein-coupled receptor kinase 2 positively regulates epithelial cell migration

scientific article

G protein-coupled receptor kinase 6 acts as a critical regulator of cytokine-induced hyperalgesia by promoting phosphatidylinositol 3-kinase and inhibiting p38 signaling.

scientific article

G protein-coupled receptor kinase 6 controls chronicity and severity of dextran sodium sulphate-induced colitis in mice.

scientific article published on 17 January 2007

G protein-coupled receptor kinase 6 controls post-inflammatory visceral hyperalgesia

scientific article

GRK2 in sensory neurons regulates epinephrine-induced signalling and duration of mechanical hyperalgesia

scientific article published on 22 April 2011

Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region

scientific article

IL4-10 Fusion Protein Is a Novel Drug to Treat Persistent Inflammatory Pain.

scientific article published on July 2016

IL4-10 fusion protein: a novel immunoregulatory drug combining activities of interleukin 4 and interleukin 10.

scientific article published on 11 November 2018

Identification of FAM173B as a protein methyltransferase promoting chronic pain.

scientific article published on 14 February 2018

Increased visceral sensitivity to capsaicin after DSS-induced colitis in mice: spinal cord c-Fos expression and behavior

Losing touch with opioids: New insights into a chemokine signaling cascade controlling morphine analgesia

scientific article published on 2 February 2014

Low nociceptor GRK2 prolongs prostaglandin E2 hyperalgesia via biased cAMP signaling to Epac/Rap1, protein kinase Cepsilon, and MEK/ERK.

scientific article published on September 2010

Mechanical allodynia

scientific article

Microglial GRK2: a novel regulator of transition from acute to chronic pain

scientific article published on 05 April 2011

Microglial/macrophage GRK2 determines duration of peripheral IL-1beta-induced hyperalgesia: contribution of spinal cord CX3CR1, p38 and IL-1 signaling.

scientific article

Monocytes/Macrophages control resolution of transient inflammatory pain.

scientific article

Neurological perspectives on voltage-gated sodium channels.

scientific article published on September 2012

Noxious mechanosensation - molecules and circuits.

scientific article

PP035. Genome-wide expression profile of first and second trimester human uterine natural killer cells.

scientific article

Physiological changes in GRK2 regulate CCL2-induced signaling to ERK1/2 and Akt but not to MEK1/2 and calcium.

scientific article published on 30 October 2007

Regulation of Nav1.7: A Conserved SCN9A Natural Antisense Transcript Expressed in Dorsal Root Ganglia.

scientific article published on 2 June 2015

Restraint stress impairs early wound healing in mice via alpha-adrenergic but not beta-adrenergic receptors

scientific article published on 6 March 2007

Significant determinants of mouse pain behaviour.

scientific article

TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells

scientific article

The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes

scientific article published on 09 February 2021

List of works by Niels Eijkelkamp

A role for G protein-coupled receptor kinase 2 in mechanical allodynia

A role for Piezo2 in EPAC1-dependent mechanical allodynia.

Amyloid Proteins and Peripheral Neuropathy

Balancing GRK2 and EPAC1 levels prevents and relieves chronic pain.

CD8+ T Cells and Endogenous IL-10 Are Required for Resolution of Chemotherapy-Induced Neuropathic Pain.

Critical role for Epac1 in inflammatory pain controlled by GRK2-mediated phosphorylation of Epac1.

First-trimester placental vascular development in multiparous women differs from that in nulliparous women

G protein-coupled receptor kinase 2 positively regulates epithelial cell migration

G protein-coupled receptor kinase 6 acts as a critical regulator of cytokine-induced hyperalgesia by promoting phosphatidylinositol 3-kinase and inhibiting p38 signaling.

G protein-coupled receptor kinase 6 controls chronicity and severity of dextran sodium sulphate-induced colitis in mice.

G protein-coupled receptor kinase 6 controls post-inflammatory visceral hyperalgesia

GRK2 in sensory neurons regulates epinephrine-induced signalling and duration of mechanical hyperalgesia

Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region

IL4-10 Fusion Protein Is a Novel Drug to Treat Persistent Inflammatory Pain.

IL4-10 fusion protein: a novel immunoregulatory drug combining activities of interleukin 4 and interleukin 10.

Identification of FAM173B as a protein methyltransferase promoting chronic pain.

Increased visceral sensitivity to capsaicin after DSS-induced colitis in mice: spinal cord c-Fos expression and behavior

Losing touch with opioids: New insights into a chemokine signaling cascade controlling morphine analgesia

Low nociceptor GRK2 prolongs prostaglandin E2 hyperalgesia via biased cAMP signaling to Epac/Rap1, protein kinase Cepsilon, and MEK/ERK.

Mechanical allodynia

Microglial GRK2: a novel regulator of transition from acute to chronic pain

Microglial/macrophage GRK2 determines duration of peripheral IL-1beta-induced hyperalgesia: contribution of spinal cord CX3CR1, p38 and IL-1 signaling.

Monocytes/Macrophages control resolution of transient inflammatory pain.

Neurological perspectives on voltage-gated sodium channels.

Noxious mechanosensation - molecules and circuits.

PP035. Genome-wide expression profile of first and second trimester human uterine natural killer cells.

Physiological changes in GRK2 regulate CCL2-induced signaling to ERK1/2 and Akt but not to MEK1/2 and calcium.

Regulation of Nav1.7: A Conserved SCN9A Natural Antisense Transcript Expressed in Dorsal Root Ganglia.

Restraint stress impairs early wound healing in mice via alpha-adrenergic but not beta-adrenergic receptors

Significant determinants of mouse pain behaviour.

TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells

The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes