List of works - Saaid Safieddine

Calcium- and otoferlin-dependent exocytosis by immature outer hair cells

scientific journal article

Choline acetyltransferase, glutamate decarboxylase, tyrosine hydroxylase, calcitonin gene-related peptide and opioid peptides coexist in lateral efferent neurons of rat and guinea-pig.

scientific article

Control of exocytosis by synaptotagmins and otoferlin in auditory hair cells

scientific article

Cysteine-string protein in inner hair cells of the organ of Corti: synaptic expression and upregulation at the onset of hearing.

scientific article published in May 2002

Different CaV1.3 Channel Isoforms Control Distinct Components of the Synaptic Vesicle Cycle in Auditory Inner Hair Cells

scientific article published on 13 February 2017

Dual AAV-mediated gene therapy restores hearing in a DFNB9 mouse model

article

Exocytotic Machineries of Vestibular Type I and Cochlear Ribbon Synapses Display Similar Intrinsic Otoferlin-Dependent Ca2+ Sensitivity But a Different Coupling to Ca2+ Channels

scientific article published on 01 August 2014

Gene therapy for human hearing loss: challenges and promises

scientific article

Hypervulnerability to Sound Exposure through Impaired Adaptive Proliferation of Peroxisomes

scientific article published in November 2015

Identification of a novel SNAP25 interacting protein (SIP30)

scientific journal article

KCNQ4, a K+ channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway.

scientific article published on April 2000

Local gene therapy durably restores vestibular function in a mouse model of Usher syndrome type 1G.

scientific article

Molecular analysis of excitatory amino acid receptor expression in the cochlea

scientific article published on January 1997

Mouse models for human hereditary deafness

scientific article published on January 2008

Myosin VI is required for the proper maturation and function of inner hair cell ribbon synapses

scientific article

Ocsyn, a novel syntaxin-interacting protein enriched in the subapical region of inner hair cells.

scientific article

Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses

scientific article published on 7 November 2017

Otoferlin is critical for a highly sensitive and linear calcium-dependent exocytosis at vestibular hair cell ribbon synapses

scientific article

Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse

scientific article

The auditory hair cell ribbon synapse: from assembly to function ⬇️

scientific article published on January 1, 2012

Triple Immunofluorescence Evidence for the Coexistence of Acetylcholine, Enkephalins and Calcitonin Gene-related Peptide Within Efferent (Olivocochlear) Neurons of Rats and Guinea-pigs.

scientific article published in January 1992

Unconventional myosin VIIA is a novel A-kinase-anchoring protein

scientific article (publication date: 22 September 2000)

Vesicle targeting in hair cells

scientific article published on 01 January 2002

alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells

scientific journal article

List of works by Saaid Safieddine

Calcium- and otoferlin-dependent exocytosis by immature outer hair cells

Choline acetyltransferase, glutamate decarboxylase, tyrosine hydroxylase, calcitonin gene-related peptide and opioid peptides coexist in lateral efferent neurons of rat and guinea-pig.

Control of exocytosis by synaptotagmins and otoferlin in auditory hair cells

Cysteine-string protein in inner hair cells of the organ of Corti: synaptic expression and upregulation at the onset of hearing.

Different CaV1.3 Channel Isoforms Control Distinct Components of the Synaptic Vesicle Cycle in Auditory Inner Hair Cells

Dual AAV-mediated gene therapy restores hearing in a DFNB9 mouse model

Exocytotic Machineries of Vestibular Type I and Cochlear Ribbon Synapses Display Similar Intrinsic Otoferlin-Dependent Ca2+ Sensitivity But a Different Coupling to Ca2+ Channels

Gene therapy for human hearing loss: challenges and promises

Hypervulnerability to Sound Exposure through Impaired Adaptive Proliferation of Peroxisomes

Identification of a novel SNAP25 interacting protein (SIP30)

KCNQ4, a K+ channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway.

Local gene therapy durably restores vestibular function in a mouse model of Usher syndrome type 1G.

Molecular analysis of excitatory amino acid receptor expression in the cochlea

Mouse models for human hereditary deafness

Myosin VI is required for the proper maturation and function of inner hair cell ribbon synapses

Ocsyn, a novel syntaxin-interacting protein enriched in the subapical region of inner hair cells.

Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses

Otoferlin is critical for a highly sensitive and linear calcium-dependent exocytosis at vestibular hair cell ribbon synapses

Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse

The auditory hair cell ribbon synapse: from assembly to function ⬇️

Triple Immunofluorescence Evidence for the Coexistence of Acetylcholine, Enkephalins and Calcitonin Gene-related Peptide Within Efferent (Olivocochlear) Neurons of Rats and Guinea-pigs.

Unconventional myosin VIIA is a novel A-kinase-anchoring protein

Vesicle targeting in hair cells

alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells