Search filters

List of works by Stephen J. Turner

A correlation between function and selected measures of T cell avidity in influenza virus-specific CD8+ T cell responses

scientific article

A semi-invariant Vα10+ T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen-recognition properties

scientific article

A structural voyage toward an understanding of the MHC‐I‐restricted immune response: lessons learned and much to be learned

scientific article published on November 1, 2012

A virus-specific CD8+ T cell immunodominance hierarchy determined by antigen dose and precursor frequencies

scientific article

Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1

scientific article published on 01 July 2020

Acute emergence and reversion of influenza A virus quasispecies within CD8+ T cell antigenic peptides

scientific article

Addition of a prominent epitope affects influenza A virus-specific CD8+ T cell immunodominance hierarchies when antigen is limiting

scientific article published in September 2006

Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses

scientific article

Age-Related Decline in Primary CD8+ T Cell Responses Is Associated with the Development of Senescence in Virtual Memory CD8+ T Cells

article

An in vivo cytotoxicity threshold for influenza A virus-specific effector and memory CD8(+) T cells

scientific article published in February 2007

Analysis of clonotype distribution and persistence for an influenza virus-specific CD8+ T cell response

scientific article published in April 2003

Anti-SIV cytolytic molecules in pigtail macaques

scientific article published in August 2008

Augmenting Influenza-Specific T Cell Memory Generation with a Natural Killer T Cell-Dependent Glycolipid-Peptide Vaccine

scientific article published on 18 October 2017

Bystander activation of CD8+ T lymphocytes during experimental mycobacterial infection.

scientific article published on December 2004

CD154+ CD4+ T-cell dependence for effective memory influenza virus-specific CD8+ T-cell responses

scientific article published on 29 April 2014

Can T cells be too exhausted to fight back?

scientific article published in December 2016

Cell cycle-related acquisition of cytotoxic mediators defines the progressive differentiation to effector status for virus-specific CD8+ T cells

scientific article published in September 2008

Characterization of CD8+ T cell repertoire diversity and persistence in the influenza A virus model of localized, transient infection

scientific article published on June 2004

Cigarette smoke worsens lung inflammation and impairs resolution of influenza infection in mice

scientific article published on 15 July 2008

Clonally diverse CD38+HLA-DR+CD8+ T cells persist during fatal H7N9 disease.

scientific article published on 26 February 2018

Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity.

scientific article

Competition within the virus-specific CD4 T-cell pool limits the T follicular helper response after influenza infection

scientific article published on 22 April 2016

Complete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchy

scientific article

Conserved T cell receptor usage in primary and recall responses to an immunodominant influenza virus nucleoprotein epitope

scholarly article

Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition

scientific article published on 23 March 2010

Contribution of T cell receptor affinity to overall avidity for virus-specific CD8+ T cell responses

scientific article

Cross-reactive CD8 + T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses

scientific article

Cutting edge: Tissue-resident memory CTL down-regulate cytolytic molecule expression following virus clearance

scientific article published in December 2007

Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis

scientific article published in April 2006

DX5/CD49b-Positive T Cells Are Not Synonymous with CD1d-Dependent NKT Cells

scientific article published on 21 September 2005

Defects in T-cell-mediated immunity to influenza virus in murine Wiskott-Aldrich syndrome are corrected by oncoretroviral vector-mediated gene transfer into repopulating hematopoietic cells

scientific article

Defining the molecular blueprint that drives CD8(+) T cell differentiation in response to infection

scientific article published on 19 December 2012

Development of a KDM6b shRNA conditional knock down mouse model

article

Differential antigen presentation regulates the changing patterns of CD8+ T cell immunodominance in primary and secondary influenza virus infections

scientific article

Differential tumor necrosis factor receptor 2-mediated editing of virus-specific CD8+ effector T cells

scholarly article

Differentiation-dependent functional and epigenetic landscapes for cytokine genes in virus-specific CD8+ T cells

scientific article

Disregulated influenza A virus-specific CD8+ T cell homeostasis in the absence of IFN-gamma signaling

scientific article

Distinct Epigenetic Signatures Delineate Transcriptional Programs during Virus-Specific CD8+ T Cell Differentiation

scientific article published in December 2014

Distinct epigenetic signatures delineate transcriptional programs during virus-specific CD8(+) T cell differentiation

scientific article published on 6 November 2014

Division-linked differentiation can account for CD8+ T-cell phenotype in vivo

scientific article published in January 2009

Dynamic regulation of permissive histone modifications and GATA3 binding underpin acquisition of granzyme A expression by virus-specific CD8(+) T cells

scientific article published on 31 October 2015

Early T-BET Expression Ensures an Appropriate CD8+ Lineage-Specific Transcriptional Landscape after Influenza A Virus Infection

scientific article published on 21 June 2019

Early establishment of diverse T cell receptor profiles for influenza-specific CD8(+)CD62L(hi) memory T cells

scholarly article

Early priming minimizes the age-related immune compromise of CD8⁺ T cell diversity and function

scientific article (publication date: February 2012)

Effect of MHC class I diversification on influenza epitope-specific CD8+ T cell precursor frequency and subsequent effector function

scientific article

Effector CD8+ T cells recovered from an influenza pneumonia differentiate to a state of focused gene expression

scientific article

Electrostatic-mediated enhancement of protein antigen immunogenicity using charged TLR2-targeting lipopeptides

scientific article published in 2012

Epigenetic plasticity of Cd8a locus during CD8(+) T-cell development and effector differentiation and reprogramming

scientific article published on 28 March 2014

Epitope-specific CD4+, but not CD8+, T-cell responses induced by recombinant influenza A viruses protect against Mycobacterium tuberculosis infection.

scientific article published on 23 December 2014

Epitope-specific TCR  repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides

scientific article

Establishment and recall of CD8+ T-cell memory in a model of localized transient infection

scientific article published on June 2006

Evaluation of recombinant influenza virus-simian immunodeficiency virus vaccines in macaques

scientific article published on 13 May 2009

Extrinsically derived TNF is primarily responsible for limiting antiviral CD8+ T cell response magnitude

scientific article published on 8 September 2017

Fixed expression of single influenza virus-specific TCR chains demonstrates the capacity for TCR α- and β-chain diversity in the face of peptide-MHC class I specificity

scientific article published on 22 December 2014

Fixing an irrelevant TCR alpha chain reveals the importance of TCR beta diversity for optimal TCR alpha beta pairing and function of virus-specific CD8+ T cells.

scientific article published in September 2010

Forewarned is forearmed

scientific article published in July 2010

Functional implications of T cell receptor diversity

scientific article published on 11 June 2009

Glucocorticoids promote apoptosis of proinflammatory monocytes by inhibiting ERK activity.

scientific article published on 15 February 2018

Glycolipid-peptide vaccination induces liver-resident memory CD8+ T cells that protect against rodent malaria

scientific article published on 01 June 2020

Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation

scientific article published on 15 August 2016

Granzyme A expression reveals distinct cytolytic CTL subsets following influenza A virus infection

scientific article

Granzyme B promotes cytotoxic lymphocyte transmigration via basement membrane remodeling.

scientific article published on 28 November 2014

Granzyme K expressing cytotoxic T lymphocytes protects against influenza virus in granzyme AB-/- mice

scientific article published in September 2008

Helping themselves: optimal virus-specific CD4 T cell responses require help via CD4 T cell licensing of dendritic cells

scientific article published on 22 October 2014

Heterogeneity of effector phenotype for acute phase and memory influenza A virus-specific CTL.

scientific article

Hierarchies in cytokine expression profiles for acute and resolving influenza virus-specific CD8+ T cell responses: correlation of cytokine profile and TCR avidity

scientific article published in May 2004

Homogenization of TCR repertoires within secondary CD62Lhigh and CD62Llow virus-specific CD8+ T cell populations

scientific article published in June 2008

IL-18, but not IL-12, is required for optimal cytokine production by influenza virus-specific CD8+ T cells

scientific article published in February 2007

Identification of conserved T cell receptor CDR3 residues contacting known exposed peptide side chains from a major histocompatibility complex class I-bound determinant

scientific article published in December 1993

Immunoproteasome subunit deficiencies impact differentially on two immunodominant influenza virus-specific CD8+ T cell responses

scientific article published in December 2006

Impact of sex steroid ablation on viral, tumour and vaccine responses in aged mice.

scientific article

Inactivated Influenza Vaccine That Provides Rapid, Innate-Immune-System-Mediated Protection and Subsequent Long-Term Adaptive Immunity

scientific article published on 27 October 2015

Influenza A virus infection impairs mycobacteria-specific T cell responses and mycobacterial clearance in the lung during pulmonary coinfection.

scientific article published on 22 May 2013

Influenza and the challenge for immunology

scientific article

Influenza epitope-specific CD8+ T cell avidity, but not cytokine polyfunctionality, can be determined by TCRβ clonotype

scientific article

Influenza-induced, helper-independent CD8+ T cell responses use CD40 costimulation at the late phase of the primary response

scientific article published on 29 October 2012

Interplay between chromatin remodeling and epigenetic changes during lineage-specific commitment to granzyme B expression

scientific article published on 13 November 2009

Intranasal lipopeptide primes lung-resident memory CD8+ T cells for long-term pulmonary protection against influenza

scientific article published in March 2006

Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations

scientific article published on 27 February 2005

Limited Phenotypic and Functional Plasticity of Influenza Virus-Specific Memory CD8 T Cells during Activation in an Alternative Cytokine Environment

scientific article published on 26 October 2018

Location rather than CD62L phenotype is critical in the early establishment of influenza-specific CD8+ T cell memory

scholarly article

Measuring the diaspora for virus-specific CD8+ T cells.

scientific article

Memories of virus-specific CD8+ T cells

scientific article published on April 2004

Memory precursor phenotype of CD8+ T cells reflects early antigenic experience rather than memory numbers in a model of localized acute influenza infection.

scientific article published on 25 January 2011

Method for assessing the similarity between subsets of the T cell receptor repertoire

scientific article published on 29 October 2007

Methods for comparing the diversity of samples of the T cell receptor repertoire

scientific article published on 21 February 2007

Mucosal HIV-1 pox virus prime-boost immunization induces high-avidity CD8+ T cells with regime-dependent cytokine/granzyme B profiles

scientific article published on February 2007

Mucosal-Associated Invariant T Cell Effector Function Is an Intrinsic Cell Property That Can Be Augmented by the Metabolic Cofactor α-Ketoglutarate

scientific article published in April 2021

Multiplexed combinatorial tetramer staining in a mouse model of virus infection.

scientific article published on 15 June 2010

Narrowed TCR diversity for immunised mice challenged with recombinant influenza A-HIV Env(311-320) virus

scientific article published on 8 September 2009

Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation

scientific article published on 05 May 2016

Oseltamivir Prophylaxis Reduces Inflammation and Facilitates Establishment of Cross-Strain Protective T Cell Memory to Influenza Viruses

scientific article

P19-24. Evaluation of recombinant influenza-SIV vaccines in macaques.

scientific article published on 22 October 2009

Predisposed αβ T cell antigen receptor recognition of MHC and MHC-I like molecules?

scientific article published on 29 August 2013

Preemptive priming readily overcomes structure-based mechanisms of virus escape

scientific article

Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion

scientific article

Priming of transcriptional memory responses via the chromatin accessibility landscape in T cells

scientific article published on 20 March 2017

Protection and compensation in the influenza virus-specific CD8+ T cell response

scientific article

Protective Efficacy of Cross-Reactive CD8+ T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation Threshold

scientific article

Q&A: What do we know about influenza and what can we do about it?

scientific article published on 26 May 2009

Q&A: What have we found out about the influenza A (H1N1) 2009 pandemic virus?

scientific article

Q&A: H1N1 pandemic influenza - what's new?

scientific article published on October 11, 2010

Quantification of repertoire diversity of influenza-specific epitopes with predominant public or private TCR usage

scientific article published on November 2006

Quantitative analysis of long-term virus-specific CD8+-T-cell memory in mice challenged with unrelated pathogens

scientific article

Regulation of H3K4me3 at Transcriptional Enhancers Characterizes Acquisition of Virus-Specific CD8+ T Cell-Lineage-Specific Function

scientific article published in December 2017

Reproducible selection of high avidity CD8+ T-cell clones following secondary acute virus infection

scientific article published on 13 January 2014

Role of CD8(+) T-cell immunity in influenza infection: potential use in future vaccine development

scientific article published in October 2009

Rotavirus replication in intestinal cells differentially regulates integrin expression by a phosphatidylinositol 3-kinase-dependent pathway, resulting in increased cell adhesion and virus yield

scientific article

Running to Stand Still: Naive CD8<sup>+</sup> T Cells Actively Maintain a Program of Quiescence

scientific article published on 21 December 2020

Shaping the T-cell repertoire in the periphery

scientific article published on 16 November 2010

Sharing of T cell receptors in antigen-specific responses is driven by convergent recombination

scholarly article

Sindbis virus vectors elicit hemagglutinin-specific humoral and cellular immune responses and offer a dose-sparing strategy for vaccination

scientific article

Soluble proteins induce strong CD8+ T cell and antibody responses through electrostatic association with simple cationic or anionic lipopeptides that target TLR2.

scientific article published on 8 July 2011

Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses

scientific article

Structural determinants of T-cell receptor bias in immunity

scientific article published on 17 November 2006

T Cell Help Amplifies Innate Signals in CD8(+) DCs for Optimal CD8(+) T Cell Priming.

scientific article published on 6 January 2016

T Cell LEGO: Identifying the Master Builders and What They Do

scientific article published on 01 February 2018

T cell antigen receptor recognition of antigen-presenting molecules

scientific article published on 10 December 2014

T cell immunity as a tool for studying epigenetic regulation of cellular differentiation

scientific article published on 12 November 2013

T cell mediated immunity to influenza: mechanisms of viral control

scientific article published on 16 July 2014

Terminal deoxynucleotidyltransferase is required for the establishment of private virus-specific CD8+ TCR repertoires and facilitates optimal CTL responses

scientific article published on August 2008

The Immune Response to Influenza A Viruses

The Impact of MHC Class I Dose on Development and Maintenance of the Polyclonal Naive CD8+ T Cell Repertoire

scientific article published on 27 April 2020

The challenge of viral immunity

scientific article published on September 2007

The context of epitope presentation can influence functional quality of recalled influenza A virus-specific memory CD8+ T cells

scientific article

The influenza virus-specific CTL immunodominance hierarchy in mice is determined by the relative frequency of high-avidity T cells

scientific article published on 2 April 2014

The linear range for accurately quantifying antigen-specific T-cell frequencies by tetramer staining during natural immune responses

scientific article published on 11 April 2011

The role of epigenetics in the acquisition and maintenance of effector function in virus-specific CD8 T cells

scientific article published on July 2010

The use of a TLR2 agonist-based adjuvant for enhancing effector and memory CD8 T-cell responses

scientific article published on 7 January 2014

Thinking About Broadly Cross-Reactive Vaccines

scientific article published on 29 April 2009

Tracking phenotypically and functionally distinct T cell subsets via T cell repertoire diversity

scientific article published on 24 August 2007

Transience of MHC Class I-restricted antigen presentation after influenza A virus infection

scholarly article

Tuning antiviral CD8 T-cell response via proline-altered peptide ligand vaccination

scientific article published on 04 May 2020

UL34 Deletion Restricts Human Cytomegalovirus Capsid Formation and Maturation

scientific article published on 21 May 2022

Unlike CD4+ T-cell help, CD28 costimulation is necessary for effective primary CD8+ T-cell influenza-specific immunity

scientific article published on 14 June 2012

Variability of inducible expression across the hematopoietic system of tetracycline transactivator transgenic mice.

scientific article

Viral modulation of the host response via crmA/SPI-2 expression.

scientific article

Visualizing CTL activity for different CD8+ effector T cells supports the idea that lower TCR/epitope avidity may be advantageous for target cell killing.

scientific article published on 9 January 2009

WASP- mice exhibit defective immune responses to influenza A virus, Streptococcus pneumoniae, and Mycobacterium bovis BCG.

scientific article published in April 2005

αβ T Cell Receptors Come Out Swinging