List of works - Finn Skou Pedersen

A murine leukemia virus with Cre-LoxP excisible coding sequences allowing superinfection, transgene delivery, and generation of host genomic deletions

scientific article

A retroviral mutagenesis screen identifies Cd74 as a common insertion site in murine B-lymphomas and reveals the existence of a novel IFNgamma-inducible Cd74 isoform

scientific article

A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus

scientific article published on 28 July 2005

A unique, thermostable dimer linkage structure of RD114 retroviral RNA.

scientific article published on 14 January 2010

Absence of xenotropic murine leukaemia virus-related virus in Danish patients with multiple sclerosis

scientific article

Activation of alternative Jdp2 promoters and functional protein isoforms in T-cell lymphomas by retroviral insertion mutagenesis

scientific article (publication date: August 2009)

Activation of the brain-specific neurogranin gene in murine T-cell lymphomas by proviral insertional mutagenesis

scientific article published on 17 April 2009

Alternative splicing, expression, and gene structure of the septin-like putative proto-oncogene Sint1.

scientific article published on February 2002

An RNA secondary structure bias for non-homologous reverse transcriptase-mediated deletions in vivo

scientific article published on 6 April 2004

Analysis of wild-type and mutant SL3-3 murine leukemia virus insertions in the c-myc promoter during lymphomagenesis reveals target site hot spots, virus-dependent patterns, and frequent error-prone gap repair

scientific article published on January 2005

Antisense transcription in gammaretroviruses as a mechanism of insertional activation of host genes

scientific article

Antiviral activity of small interfering RNAs: specificity testing using heterologous virus reveals interferon-related effects overlooked by conventional mismatch controls

scientific article published on 15 February 2006

Bestrophin-3 (vitelliform macular dystrophy 2-like 3 protein) is essential for the cGMP-dependent calcium-activated chloride conductance in vascular smooth muscle cells

scientific article

Change of tropism of SL3-2 murine leukemia virus, using random mutational libraries

scientific article

Co-localization of gammaretroviral RNAs at their transcription site favours co-packaging

scientific article published on August 2006

Complementarity between RNA dimerization elements favors formation of functional heterozygous murine leukemia viruses

scientific article

Complementarity-directed RNA dimer-linkage promotes retroviral recombination in vivo

scientific article published on 9 January 2004

Construction of a gammaretrovirus with a novel tropism and wild-type replication kinetics capable of using human APJ as entry receptor

scientific article published on 18 July 2012

Control of pathogenicity and disease specificity of a T-lymphomagenic gammaretrovirus by E-box motifs but not by an overlapping glucocorticoid response element

scientific article published on 22 October 2008

Correction: Restriction Genes for Retroviruses Influence the Risk of Multiple Sclerosis.

scientific article published on 24 October 2013

Coupling of receptor interference and a host-dependent post-binding entry deficiency in a gammaretroviral envelope protein

scientific article published on 5 February 2010

Deregulated Nras expression in knock-in animals harboring a gammaretroviral long terminal repeat at the Nras/Csde1 locus

scientific article

Distinct roles of enhancer nuclear factor 1 (NF1) sites in plasmacytoma and osteopetrosis induction by Akv1-99 murine leukemia virus

scientific article

Efficient replication of full-length murine leukemia viruses modified at the dimer initiation site regions

scientific article published on January 2004

Endogenous retroviruses and multiple sclerosis-new pieces to the puzzle.

scientific article

Enhancer mutations of Akv murine leukemia virus inhibit the induction of mature B-cell lymphomas and shift disease specificity towards the more differentiated plasma cell stage

scientific article published on 29 January 2007

Epigenetic marking and repression of porcine endogenous retroviruses

scientific article published on 16 January 2013

Ethical perspectives on RNA interference therapeutics

scientific article published on 25 June 2008

Expression of Gag and Pol from reconstructed HERV-Fc1, associated with multiple sclerosis.

scientific article published on 3 October 2011

Functional selection of shRNA loops from randomized retroviral libraries

scientific article

Fv1-like restriction of N-tropic replication-competent murine leukaemia viruses in mCAT-1-expressing human cells

scientific article published on February 2002

Gene conversion and purifying selection of a placenta-specific ERV-V envelope gene during simian evolution

scientific article

Gene expression profiling of murine T-cell lymphoblastic lymphoma identifies deregulation of S-phase initiating genes

scientific article

Human endogenous retroviruses sustain complex and cooperative regulation of gene-containing loci and unannotated megabase-sized regions

scientific article published on 17 April 2015

Identification of distinct topographical surface microstructures favoring either undifferentiated expansion or differentiation of murine embryonic stem cells

scientific article

Identification of endogenous retroviral reading frames in the human genome

scientific article

Identification of novel Bach2 transcripts and protein isoforms through tagging analysis of retroviral integrations in B-cell lymphomas

scientific article

Immune suppressive activity of the influenza fusion peptide

scientific article published on 14 October 2015

Impairment of alternative splice sites defining a novel gammaretroviral exon within gag modifies the oncogenic properties of Akv murine leukemia virus

scientific article published on 6 July 2007

In vivo infection of mice by replication-competent MLV-based retroviral vectors

scientific article published on January 2003

Interaction of human mesenchymal stem cells with osteopontin coated hydroxyapatite surfaces

scientific article published on 25 August 2009

Ligand presentation on a synthetic flexible hinge in Moloney murine leukemia virus SU supports entry via a heterologous receptor

scientific article

Loss of MicroRNA targets in the 3' untranslated region as a mechanism of retroviral insertional activation of growth factor independence 1.

scientific article published on 27 May 2009

Modulation of homo- and heterodimerization of Harvey sarcoma virus RNA by GACG tetraloops and point mutations in palindromic sequences

scientific article published in November 2002

Molecular strategies to inhibit HIV-1 replication

scientific article

Mutation of all Runx (AML1/core) sites in the enhancer of T-lymphomagenic SL3-3 murine leukemia virus unmasks a significant potential for myeloid leukemia induction and favors enhancer evolution toward induction of other disease patterns

scientific article published on December 2004

Mutational library analysis of selected amino acids in the receptor binding domain of envelope of Akv murine leukemia virus by conditionally replication competent bicistronic vectors

scientific article published in October 2003

No additional copies of HERV-Fc1 in the germ line of multiple sclerosis patients

scientific article

Non-identical patterns of proviral insertions around host transcription units in lymphomas induced by different strains of murine leukemia virus

scientific article published on 21 June 2006

Novel principles of gamma-retroviral insertional transcription activation in murine leukemia virus-induced end-stage tumors

scientific article

Nras overexpression results in granulocytosis, T-cell expansion and early lethality in mice

scientific article

Proximity ligation assay combined with flow cytometry is a powerful tool for the detection of cytokine receptor dimerization

scientific article

Quantitative evaluation of the murine B16 melanoma tumor model after gene marking with an EGFP/Neo expressing retroviral vector.

scientific article published on May 2002

Reducing mobilization of simian immunodeficiency virus based vectors by primer complementation

scientific article published on February 2004

Restriction genes for retroviruses influence the risk of multiple sclerosis

scientific article

Safety features of retroviral vectors.

scientific article

Silencing of endogenous envelope genes in human choriocarcinoma cells shows that envPb1 is involved in heterotypic cell fusions

scientific article published on 9 May 2012

Strand transfer to the 5' part of a tRNA as a mechanism for retrovirus patch-repair recombination in vivo

scientific article published on July 2004

Target-cell-derived tRNA-like primers for reverse transcription support retroviral infection at low efficiency

scientific article published on May 2002

The Icsbp locus is a common proviral insertion site in mature B-cell lymphomas/plasmacytomas induced by exogenous murine leukemia virus

scientific article published on 15 June 2006

The approximately 30-million-year-old ERVPb1 envelope gene is evolutionarily conserved among hominoids and Old World monkeys

scientific article published on 2 November 2005

The etiology of multiple sclerosis: genetic evidence for the involvement of the human endogenous retrovirus HERV-Fc1

scientific article (publication date: 2 February 2011)

The use of combinatorial topographical libraries for the screening of enhanced osteogenic expression and mineralization

scientific article

Transgene stability for three replication-competent murine leukemia virus vectors

scientific article published on March 2004

Triple basepair changes within and adjacent to the conserved YY1 motif upstream of the U3 enhancer repeats of SL3-3 murine leukemia virus cause a small but significant shortening of latency of T-lymphoma induction

scientific article published in September 2003

Two Virus-Induced MicroRNAs Known Only from Teleost Fishes Are Orthologues of MicroRNAs Involved in Cell Cycle Control in Humans

scientific article published on 24 July 2015

Utility of next-generation RNA-sequencing in identifying chimeric transcription involving human endogenous retroviruses

scientific article published on January 2016

List of works by Finn Skou Pedersen

A murine leukemia virus with Cre-LoxP excisible coding sequences allowing superinfection, transgene delivery, and generation of host genomic deletions

A retroviral mutagenesis screen identifies Cd74 as a common insertion site in murine B-lymphomas and reveals the existence of a novel IFNgamma-inducible Cd74 isoform

A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus

A unique, thermostable dimer linkage structure of RD114 retroviral RNA.

Absence of xenotropic murine leukaemia virus-related virus in Danish patients with multiple sclerosis

Activation of alternative Jdp2 promoters and functional protein isoforms in T-cell lymphomas by retroviral insertion mutagenesis

Activation of the brain-specific neurogranin gene in murine T-cell lymphomas by proviral insertional mutagenesis

Alternative splicing, expression, and gene structure of the septin-like putative proto-oncogene Sint1.

An RNA secondary structure bias for non-homologous reverse transcriptase-mediated deletions in vivo

Analysis of wild-type and mutant SL3-3 murine leukemia virus insertions in the c-myc promoter during lymphomagenesis reveals target site hot spots, virus-dependent patterns, and frequent error-prone gap repair

Antisense transcription in gammaretroviruses as a mechanism of insertional activation of host genes

Antiviral activity of small interfering RNAs: specificity testing using heterologous virus reveals interferon-related effects overlooked by conventional mismatch controls

Bestrophin-3 (vitelliform macular dystrophy 2-like 3 protein) is essential for the cGMP-dependent calcium-activated chloride conductance in vascular smooth muscle cells

Change of tropism of SL3-2 murine leukemia virus, using random mutational libraries

Co-localization of gammaretroviral RNAs at their transcription site favours co-packaging

Complementarity between RNA dimerization elements favors formation of functional heterozygous murine leukemia viruses

Complementarity-directed RNA dimer-linkage promotes retroviral recombination in vivo

Construction of a gammaretrovirus with a novel tropism and wild-type replication kinetics capable of using human APJ as entry receptor

Control of pathogenicity and disease specificity of a T-lymphomagenic gammaretrovirus by E-box motifs but not by an overlapping glucocorticoid response element

Correction: Restriction Genes for Retroviruses Influence the Risk of Multiple Sclerosis.

Coupling of receptor interference and a host-dependent post-binding entry deficiency in a gammaretroviral envelope protein

Deregulated Nras expression in knock-in animals harboring a gammaretroviral long terminal repeat at the Nras/Csde1 locus

Distinct roles of enhancer nuclear factor 1 (NF1) sites in plasmacytoma and osteopetrosis induction by Akv1-99 murine leukemia virus

Efficient replication of full-length murine leukemia viruses modified at the dimer initiation site regions

Endogenous retroviruses and multiple sclerosis-new pieces to the puzzle.

Enhancer mutations of Akv murine leukemia virus inhibit the induction of mature B-cell lymphomas and shift disease specificity towards the more differentiated plasma cell stage

Epigenetic marking and repression of porcine endogenous retroviruses

Ethical perspectives on RNA interference therapeutics

Expression of Gag and Pol from reconstructed HERV-Fc1, associated with multiple sclerosis.

Functional selection of shRNA loops from randomized retroviral libraries

Fv1-like restriction of N-tropic replication-competent murine leukaemia viruses in mCAT-1-expressing human cells

Gene conversion and purifying selection of a placenta-specific ERV-V envelope gene during simian evolution

Gene expression profiling of murine T-cell lymphoblastic lymphoma identifies deregulation of S-phase initiating genes

Human endogenous retroviruses sustain complex and cooperative regulation of gene-containing loci and unannotated megabase-sized regions

Identification of distinct topographical surface microstructures favoring either undifferentiated expansion or differentiation of murine embryonic stem cells

Identification of endogenous retroviral reading frames in the human genome

Identification of novel Bach2 transcripts and protein isoforms through tagging analysis of retroviral integrations in B-cell lymphomas

Immune suppressive activity of the influenza fusion peptide

Impairment of alternative splice sites defining a novel gammaretroviral exon within gag modifies the oncogenic properties of Akv murine leukemia virus

In vivo infection of mice by replication-competent MLV-based retroviral vectors

Interaction of human mesenchymal stem cells with osteopontin coated hydroxyapatite surfaces

Ligand presentation on a synthetic flexible hinge in Moloney murine leukemia virus SU supports entry via a heterologous receptor

Loss of MicroRNA targets in the 3' untranslated region as a mechanism of retroviral insertional activation of growth factor independence 1.

Modulation of homo- and heterodimerization of Harvey sarcoma virus RNA by GACG tetraloops and point mutations in palindromic sequences

Molecular strategies to inhibit HIV-1 replication

Mutation of all Runx (AML1/core) sites in the enhancer of T-lymphomagenic SL3-3 murine leukemia virus unmasks a significant potential for myeloid leukemia induction and favors enhancer evolution toward induction of other disease patterns

Mutational library analysis of selected amino acids in the receptor binding domain of envelope of Akv murine leukemia virus by conditionally replication competent bicistronic vectors

No additional copies of HERV-Fc1 in the germ line of multiple sclerosis patients

Non-identical patterns of proviral insertions around host transcription units in lymphomas induced by different strains of murine leukemia virus

Novel principles of gamma-retroviral insertional transcription activation in murine leukemia virus-induced end-stage tumors

Nras overexpression results in granulocytosis, T-cell expansion and early lethality in mice

Proximity ligation assay combined with flow cytometry is a powerful tool for the detection of cytokine receptor dimerization

Quantitative evaluation of the murine B16 melanoma tumor model after gene marking with an EGFP/Neo expressing retroviral vector.

Reducing mobilization of simian immunodeficiency virus based vectors by primer complementation

Restriction genes for retroviruses influence the risk of multiple sclerosis

Safety features of retroviral vectors.

Silencing of endogenous envelope genes in human choriocarcinoma cells shows that envPb1 is involved in heterotypic cell fusions

Strand transfer to the 5' part of a tRNA as a mechanism for retrovirus patch-repair recombination in vivo

Target-cell-derived tRNA-like primers for reverse transcription support retroviral infection at low efficiency

The Icsbp locus is a common proviral insertion site in mature B-cell lymphomas/plasmacytomas induced by exogenous murine leukemia virus

The approximately 30-million-year-old ERVPb1 envelope gene is evolutionarily conserved among hominoids and Old World monkeys

The etiology of multiple sclerosis: genetic evidence for the involvement of the human endogenous retrovirus HERV-Fc1

The use of combinatorial topographical libraries for the screening of enhanced osteogenic expression and mineralization

Transgene stability for three replication-competent murine leukemia virus vectors

Triple basepair changes within and adjacent to the conserved YY1 motif upstream of the U3 enhancer repeats of SL3-3 murine leukemia virus cause a small but significant shortening of latency of T-lymphoma induction

Two Virus-Induced MicroRNAs Known Only from Teleost Fishes Are Orthologues of MicroRNAs Involved in Cell Cycle Control in Humans

Utility of next-generation RNA-sequencing in identifying chimeric transcription involving human endogenous retroviruses