List of works by Manon van Engeland

A Four-Gene Promoter Methylation Marker Panel Consisting of GREM1, NEURL, LAD1, and NEFH Predicts Survival of Clear Cell Renal Cell Cancer Patients

scientific article

A combined literature and in silico analysis enlightens the role of the NDRG family in the gut

scientific article published on 07 July 2018

A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer

scientific article

A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer

scientific article published on 12 October 2011

A novel classification of colorectal tumors based on microsatellite instability, the CpG island methylator phenotype and chromosomal instability: implications for prognosis.

scientific article

APC mutations in sporadic colorectal carcinomas from The Netherlands Cohort Study

scientific article published on 19 February 2004

Alcohol and Dietary Folate Intake and Promoter CpG Island Methylation in Clear-Cell Renal Cell Cancer

scientific article published on 24 June 2016

Alcohol consumption and mutations or promoter hypermethylation of the von Hippel-Lindau gene in renal cell carcinoma.

scientific article

Alcohol consumption, alcohol dehydrogenase 1C (ADH1C) genotype, and risk of colorectal cancer in the Netherlands Cohort Study on diet and cancer.

scientific article published on 15 December 2010

An exploration of pathways involved in lung carcinoid progression using gene expression profiling.

scientific article published on 8 August 2013

Analysis of DNA methylation in cancer: location revisited

scientific article published on 01 July 2018

Analysis of RET promoter CpG island methylation using methylation-specific PCR (MSP), pyrosequencing, and methylation-sensitive high-resolution melting (MS-HRM): impact on stage II colon cancer patient outcome

scientific article published on 26 April 2016

Analysis of promoter CpG island hypermethylation in cancer: location, location, location!

scientific article published on 10 May 2011

Analytical sensitivity and stability of DNA methylation testing in stool samples for colorectal cancer detection.

scientific article

Angiostatic activity of DNA methyltransferase inhibitors

scientific article published in February 2006

Assessing opportunities for coordinated R&D in early cancer detection and management in Europe

scientific article published on 10 December 2016

Associations of dietary methyl donor intake with MLH1 promoter hypermethylation and related molecular phenotypes in sporadic colorectal cancer

scientific article published on 13 March 2008

Author Correction: Analysis of DNA methylation in cancer: location revisited

scientific article published on 01 July 2018

Body size and colorectal cancer risk after 16.3 years of follow-up: an analysis from the Netherlands Cohort Study

scientific article published on 7 October 2011

Body size and risk for colorectal cancers showing BRAF mutations or microsatellite instability: a pooled analysis

scientific article published on 24 April 2012

Body size, physical activity and risk of colorectal cancer with or without the CpG island methylator phenotype (CIMP).

scientific article

Body size, physical activity, early-life energy restriction, and associations with methylated insulin-like growth factor-binding protein genes in colorectal cancer

scientific article published on 27 June 2014

Body size, physical activity, genetic variants in the insulin-like growth factor pathway and colorectal cancer risk.

scientific article published on 29 May 2015

CD44 and OTP are strong prognostic markers for pulmonary carcinoids

scientific article published on 26 February 2013

CHFR promoter hypermethylation in colon cancer correlates with the microsatellite instability phenotype.

scientific article

CHFR promoter methylation indicates poor prognosis in stage II microsatellite stable colorectal cancer

scientific article published in June 2014

Can a biomarker triage test reduce colonoscopy burden in fecal immunochemical test screening?

scientific article published on 28 May 2020

Characteristics of triple-negative breast cancer

scientific article

Childhood and adolescent energy restriction and subsequent colorectal cancer risk: results from the Netherlands Cohort Study

scientific article

Chordoma: the entity

scientific article

Chromosome 5q loss in colorectal flat adenomas.

scientific article published on 3 July 2012

Colorectal cancer epigenetics: complex simplicity

scientific article published on 10 January 2011

Comparing the DNA hypermethylome with gene mutations in human colorectal cancer

scientific article

Comprehensive mutation analysis in colorectal flat adenomas ⬇️

scientific article

Cost-effectiveness of High-performance Biomarker Tests vs Fecal Immunochemical Test for Noninvasive Colorectal Cancer Screening

scientific article published on 18 July 2017

DNA methylation of phosphatase and actin regulator 3 detects colorectal cancer in stool and complements FIT.

scientific article published in December 2011

Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer ⬇️

scientific article published on 27 June 2017

Details matter: the role of genomic location and assay standardization in DNA methylation analyses

scientific article published on 15 June 2017

Diagnostic DNA Methylation Biomarkers for Renal Cell Carcinoma: A Systematic Review

scientific article published on 09 August 2019

Dietary acrylamide intake and the risk of colorectal cancer with specific mutations in KRAS and APC.

scientific article published on 7 January 2014

Dietary folate and APC mutations in sporadic colorectal cancer.

scientific article published in December 2006

Dietary folate intake and k-ras mutations in sporadic colon and rectal cancer in The Netherlands Cohort Study

scientific article published on May 2005

Dietary folate intake in combination with MTHFR C677T genotype and promoter methylation of tumor suppressor and DNA repair genes in sporadic colorectal adenomas

scientific article published on 01 February 2007

Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer

scientific article published in December 2008

Dietary heme iron and the risk of colorectal cancer with specific mutations in KRAS and APC.

scientific article published on 27 August 2013

Dietary methyl donors, methyl metabolizing enzymes, and epigenetic regulators: diet-gene interactions and promoter CpG island hypermethylation in colorectal cancer

scientific article

Different angiogenic potential in low and high grade sporadic clear cell renal cell carcinoma is not related to alterations in the von Hippel-Lindau gene.

scientific article published in January 2009

Differential gene expression in ovarian tumors reveals Dusp 4 and Serpina 5 as key regulators for benign behavior of serous borderline tumors

scientific article published on 8 August 2005

Dual targeting of epigenetic therapy in cancer

scientific article published on 21 July 2006

Early life exposure to famine and colorectal cancer risk: a role for epigenetic mechanisms

scientific article

Early onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition?

scientific article

Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: the Netherlands cohort study on diet and cancer

scientific article

Emerging evidence for CHFR as a cancer biomarker: from tumor biology to precision medicine

scientific article published on March 2014

Energy restriction at young age, genetic variants in the insulin-like growth factor pathway and colorectal cancer risk in the Netherlands Cohort Study

scientific article

Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone Modifications

scientific article published on 01 November 2006

Epigenetic changes in Basal Cell Carcinoma affect SHH and WNT signaling components

scientific article

Epigenetics in radiotherapy: where are we heading?

scientific article published on 23 May 2014

Epigenetics in renal cell cancer: mechanisms and clinical applications

scientific article published on 01 July 2018

Folic acid and vitamin B-12 supplementation does not favorably influence uracil incorporation and promoter methylation in rectal mucosa DNA of subjects with previous colorectal adenomas.

scientific article published in September 2007

Formalin-fixed, paraffin-embedded (FFPE) tissue epigenomics using Infinium HumanMethylation450 BeadChip assays

scientific article published on 13 April 2015

GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer

scientific article

GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer

scientific article

Gene Promoter Methylation in Endometrial Carcinogenesis

scientific article published on 14 November 2018

Genetic Variants in the Insulin-like Growth Factor Pathway and Colorectal Cancer Risk in the Netherlands Cohort Study

scientific article

Genetic and epigenetic alterations in the von hippel-lindau gene: the influence on renal cancer prognosis.

scientific article published in February 2008

Genetic variants of methyl metabolizing enzymes and epigenetic regulators: associations with promoter CpG island hypermethylation in colorectal cancer

scientific article published on 20 October 2009

Genetics and epigenetics of cutaneous malignant melanoma: a concert out of tune.

scientific article published on 31 March 2012

Genetics and epigenetics of renal cell cancer

scientific article published on 15 December 2007

Genomic and epigenomic integration identifies a prognostic signature in colon cancer

scientific article

Germline polymorphisms in the Von Hippel-Lindau and Hypoxia-inducible factor 1-alpha genes, gene-environment and gene-gene interactions and renal cell cancer

scientific article published on 10 January 2020

Identification of Epigenetically Silenced Genes in Tumor Endothelial Cells

article

Integrated analysis of chromosomal, microsatellite and epigenetic instability in colorectal cancer identifies specific associations between promoter methylation of pivotal tumour suppressor and DNA repair genes and specific chromosomal alterations.

scientific article published on 28 November 2007

Investigation of sirtuin 1 polymorphisms in relation to the risk of colorectal cancer by molecular subtype

scientific article published on 25 February 2020

K-ras mutations and RASSF1A promoter methylation in colorectal cancer

scientific article published in May 2002

Lamin A/C is a risk biomarker in colorectal cancer

scientific article

Lifestyle, Diet, and Colorectal Cancer Risk According to (Epi)genetic Instability: Current Evidence and Future Directions of Molecular Pathological Epidemiology

scientific article published on 2 December 2017

Long-term dietary sodium, potassium and fluid intake; exploring potential novel risk factors for renal cell cancer in the Netherlands Cohort Study on diet and cancer

scientific article published on 10 December 2013

Loss of SerpinA5 protein expression is associated with advanced-stage serous ovarian tumors ⬇️

scientific article published on November 19, 2010

MEN1 gene mutation and reduced expression are associated with poor prognosis in pulmonary carcinoids.

scientific article published on 25 November 2013

MEXPRESS update 2019

scientific article published on 01 July 2019

Methylation of RASSF10 promotes cell proliferation and serves as a docetaxel resistant marker in human breast cancer

scientific article published in November 2015

Methylation-associated dysregulation of the suppressor of cytokine signaling-3 gene in multiple myeloma

scientific article published on August 2011

Methylation-specific PCR unraveled.

scientific article

Mitochondrial DNA copy number in colorectal cancer: between tissue comparisons, clinicopathological characteristics and survival

scientific article published on 17 October 2015

Molecular stool testing as an alternative for surveillance colonoscopy: a cross-sectional cohort study

scientific article

Molecular tests for colorectal cancer screening

scientific article published on March 2011

N-Myc downstream-regulated gene 4 (NDRG4): a candidate tumor suppressor gene and potential biomarker for colorectal cancer

scientific article

Past, Present and Future of Epigenetics in Adrenocortical Carcinoma

scientific article published on 13 May 2020

Pharmacoepigenomics in colorectal cancer: a step forward in predicting prognosis and treatment response

scientific article published on December 2008

Physical activity, occupational sitting time, and colorectal cancer risk in the Netherlands cohort study

scientific article published on 17 February 2013

Polymorphisms in genes of the renin-angiotensin-aldosterone system and renal cell cancer risk: interplay with hypertension and intakes of sodium, potassium and fluid.

scientific article published on 10 July 2014

Potential role of gene-environment interactions in ion transport mechanisms in the etiology of renal cell cancer

scientific article published on 30 September 2016

Prognostic DNA methylation markers for hormone receptor breast cancer: a systematic review

scientific article published on 31 January 2020

Prognostic DNA methylation markers for renal cell carcinoma: a systematic review

scientific article published on 14 August 2017

Prognostic DNA methylation markers for sporadic colorectal cancer: a systematic review. ⬇️

scientific article published on 14 March 2018

Prognostic Significance of Promoter Hypermethylation and Diminished Gene Expression of SYNPO2 in Melanoma ⬇️

scientific article

Prognostic significance of Gremlin1 (GREM1) promoter CpG island hypermethylation in clear cell renal cell carcinoma

scientific article

Promoter CpG island hypermethylation in dysplastic nevus and melanoma: CLDN11 as an epigenetic biomarker for malignancy

scientific article published on 7 July 2014

Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21.

scientific article published on 27 March 2009

Promoter CpG island methylation in ion transport mechanisms and associated dietary intakes jointly influence the risk of clear-cell renal cell cancer

scientific article

Promoter CpG island methylation markers in colorectal cancer: the road ahead

scientific article published on April 2012

Promoter CpG island methylation of RET predicts poor prognosis in stage II colorectal cancer patients

scientific article published on 2 February 2014

Promoter Methylation of CDO1 Identifies Clear-Cell Renal Cell Cancer Patients with Poor Survival Outcome

scientific article

Promoter methylation of Wnt-antagonists in polypoid and nonpolypoid colorectal adenomas ⬇️

scientific article

Promoter methylation precedes chromosomal alterations in colorectal cancer development.

scientific article

SOX17 expression and its down-regulation by promoter methylation in cervical adenocarcinoma in situ and adenocarcinoma

scientific article published on 01 December 2019

Spectrin repeat containing nuclear envelope 1 and forkhead box protein E1 are promising markers for the detection of colorectal cancer in blood

scientific article

Stromal expression of hypoxia regulated proteins is an adverse prognostic factor in colorectal carcinomas.

scientific article

Switches of SOX17 and SOX2 expression in the development of squamous metaplasia and squamous intraepithelial lesions of the uterine cervix

scientific article published on 09 July 2020

TP53 overexpression in recurrent endometrial carcinoma.

scientific article

Taxane resistance in breast cancer: a closed HER2 circuit?

scientific article published on 18 January 2012

Test performance of immunologic fecal occult blood testing and sigmoidoscopy compared with primary colonoscopy screening for colorectal advanced adenomas

scientific article published on 12 July 2011

The CpG island methylator phenotype in colorectal cancer: progress and problems

scientific article

The CpG island methylator phenotype: what's in a name?

scientific article

The N-myc downstream regulated gene (NDRG) family: diverse functions, multiple applications

scientific article published on 28 July 2010

The adenoma hunt in colorectal cancer screening: defining the target

scientific article

The emerging role of GATA transcription factors in development and disease

scientific article

The mTOR Pathway and the Role of Energy Balance Throughout Life in Colorectal Cancer Etiology and Prognosis: Unravelling Mechanisms Through a Multidimensional Molecular Epidemiologic Approach

scientific article published on 8 January 2013

The trans-DATA study: aims and design of a translational breast cancer prognostic marker identification study

scientific article published on 17 October 2019

Tracking the molecular features of nonpolypoid colorectal neoplasms: a systematic review and meta-analysis

scientific article published on 07 May 2013

VHL and HIF signalling in renal cell carcinogenesis

scientific article published on June 2010

Viewing the epigenetics of colorectal cancer through the window of folic acid effects

scientific article published on December 2010

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