List of works by Heike Irmgard Grabsch

A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets ⬇️

scientific article published on 7 February 2012

A multidisciplinary approach to management of autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED).

scientific article published on 30 January 2013

Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A. ⬇️

scientific article published on 29 December 2015

Biopsy proportion of tumour predicts pathological tumour response and benefit from chemotherapy in resectable oesophageal carcinoma: results from the UK MRC OE02 trial ⬇️

scientific article published on 18 October 2016

CRITICS-II: a multicentre randomised phase II trial of neo-adjuvant chemotherapy followed by surgery versus neo-adjuvant chemotherapy and subsequent chemoradiotherapy followed by surgery versus neo-adjuvant chemoradiotherapy followed by surgery in re ⬇️

Candidate driver genes in focal chromosomal aberrations of stage II colon cancer

scientific article published in August 2010

Chromosome 5q loss in colorectal flat adenomas.

scientific article published on 3 July 2012

Clinicopathological and molecular factors related to chromosomal instability and its underlying genetic mechanisms in gastric cancer

doctoral thesis

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

scientific article

Comprehensive genomic meta-analysis identifies intra-tumoural stroma as a predictor of survival in patients with gastric cancer

scientific article published on 26 June 2012

Comprehensive mutation analysis in colorectal flat adenomas ⬇️

scientific article

Consensus statements for management of Barrett's dysplasia and early-stage esophageal adenocarcinoma, based on a Delphi process

scientific article published on 24 April 2012

Correction to: KRAS status is related to histological phenotype in gastric cancer: results from a large multicentre study

scientific article published on 01 November 2019

DNA quality assessment for array CGH by isothermal whole genome amplification.

scientific article

Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer

scientific article published on 03 June 2019

Effect of Pathologic Tumor Response and Nodal Status on Survival in the Medical Research Council Adjuvant Gastric Infusional Chemotherapy Trial ⬇️

scientific article

EphB2 is a prognostic factor in colorectal cancer

scientific article published in July 2005

Erratum to: Histopathological, Molecular, and Genetic Profile of Hereditary Diffuse Gastric Cancer: Current Knowledge and Challenges for the Future

scientific article published on January 2016

Expression of BUB1 protein in gastric cancer correlates with the histological subtype, but not with DNA ploidy or microsatellite instability

scientific article published in February 2004

Expression of DNA double-strand break repair proteins ATM and BRCA1 predicts survival in colorectal cancer

scientific article published in March 2006

Five biopsy specimens from the proximal part of the tumor reliably determine HER2 protein expression status in gastric cancer ⬇️

scientific article published on 19 May 2015

Gastric cancer pathology and underlying molecular mechanisms

scientific article published on 18 July 2013

Gastric cancers of Western European and African patients show different patterns of genomic instability

scientific article

Genetic and structural variation in the gastric cancer kinome revealed through targeted deep sequencing

scientific article

Guidelines and considerations for conducting experiments using tissue microarrays

scientific article published on 12 April 2013

HER2 expression in gastric cancer: Rare, heterogeneous and of no prognostic value - conclusions from 924 cases of two independent series.

scientific article published in January 2010

High resolution analysis of DNA copy-number aberrations of chromosomes 8, 13, and 20 in gastric cancers

scientific article published on 21 August 2009

High-level copy number gains of established and potential drug target genes in gastric cancer as a lead for treatment development and selection.

scientific article published on 31 December 2013

Histopathological, Molecular, and Genetic Profile of Hereditary Diffuse Gastric Cancer: Current Knowledge and Challenges for the Future ⬇️

scientific article published on January 2016

Hypothesis-free deep survival learning applied to the tumour microenvironment in gastric cancer

scientific article published on 27 June 2020

Identification of a high-risk subtype of intestinal-type Japanese gastric cancer by quantitative measurement of the luminal tumor proportion

scientific article published on 29 August 2018

Immunodetection of alpha1E voltage-gated Ca(2+) channel in chromogranin-positive muscle cells of rat heart, and in distal tubules of human kidney

scientific article

Immunohistochemical detection of alpha1E voltage-gated Ca(2+) channel isoforms in cerebellum, INS-1 cells, and neuroendocrine cells of the digestive system

scientific article

Immunotherapy in gastrointestinal cancer: Recent results, current studies and future perspectives ⬇️

scientific article published on 31 March 2016

Inhibition of gastric cancer invasion and metastasis by PLA2G2A, a novel beta-catenin/TCF target gene

scientific article

Integrative genomics identifies RAB23 as an invasion mediator gene in diffuse-type gastric cancer

scientific article

Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapy

scientific article

KRAS and BRAF mutations in Nigerian colorectal cancers

scientific article published on July 2012

KRAS status is related to histological phenotype in gastric cancer: results from a large multicentre study

scientific article published on 20 May 2019

Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 up-regulation in intestinal gastric cancer

scientific article

Losses of chromosome 5q and 14q are associated with favorable clinical outcome of patients with gastric cancer

scientific article

Low levels of IgM antibodies recognizing oxidation-specific epitopes are associated with human non-alcoholic fatty liver disease ⬇️

scientific article

Low molecular weight heat shock protein HSP27 is a prognostic indicator in rectal cancer but not colon cancer

scientific article published in November 2010

Lymph node response to chemoradiotherapy in oesophageal cancer patients: relationship with radiotherapy fields

scientific article published on 05 September 2020

MRI for Local Staging of Colon Cancer: Can MRI Become the Optimal Staging Modality for Patients With Colon Cancer? ⬇️

scientific article published on April 2017

Mixed gastric carcinomas show similar chromosomal aberrations in both their diffuse and glandular components

article published in 2006

Mucin expression in gastric- and gastro-oesophageal signet-ring cell cancer: results from a comprehensive literature review and a large cohort study of Caucasian and Asian gastric cancer

scientific article published on 02 June 2020

NEOSCOPE: A randomised Phase II study of induction chemotherapy followed by either oxaliplatin/capecitabine (OXCAP) or carboplatin/paclitaxel (CarPac) based chemoradiation (CRT) as pre-operative regimen for resectable oesophageal adenocarcinoma

scientific article published in February 2016

NEOSCOPE: A randomised phase II study of induction chemotherapy followed by oxaliplatin/capecitabine or carboplatin/paclitaxel based pre-operative chemoradiation for resectable oesophageal adenocarcinoma ⬇️

scientific article published on 08 February 2017

NEOSCOPE: a randomised Phase II study of induction chemotherapy followed by either oxaliplatin/capecitabine or paclitaxel/carboplatin based chemoradiation as pre-operative regimen for resectable oesophageal adenocarcinoma ⬇️

scientific article

Neoadjuvant cisplatin and fluorouracil versus epirubicin, cisplatin, and capecitabine followed by resection in patients with oesophageal adenocarcinoma (UK MRC OE05): an open-label, randomised phase 3 trial ⬇️

scientific article published on 04 August 2017

New isoform of the neuronal Ca2+ channel alpha1E subunit in islets of Langerhans and kidney--distribution of voltage-gated Ca2+ channel alpha1 subunits in cell lines and tissues

scientific article published on October 1998

Oncogenic pathway combinations predict clinical prognosis in gastric cancer.

scientific article published on 02 October 2009

Overexpression of the mitotic checkpoint genes BUB1, BUBR1, and BUB3 in gastric cancer--association with tumour cell proliferation.

scientific article

Prognostic DNA methylation markers for sporadic colorectal cancer: a systematic review. ⬇️

scientific article published on 14 March 2018

Prognostic significance of cancer within 1 mm of the circumferential resection margin in oesophageal cancer patients following neo-adjuvant chemotherapy

scientific article

Prognostic value of cyclin B1 protein expression in colorectal cancer.

scientific article published in October 2004

Prognostic value of pathological lymph node status and primary tumour regression grading following neoadjuvant chemotherapy - results from the MRC OE02 oesophageal cancer trial. ⬇️

scientific article published on 21 February 2018

Promoter methylation of Wnt-antagonists in polypoid and nonpolypoid colorectal adenomas ⬇️

scientific article

Q-FISH analysis of telomere and chromosome instability in the oesophagus with and without squamous cell carcinoma in situ

scientific article published on June 2010

RandomSpot: A web-based tool for systematic random sampling of virtual slides

scientific article published on 24 February 2015

Reduced genomic tumor heterogeneity after neoadjuvant chemotherapy is related to favorable outcome in patients with esophageal adenocarcinoma ⬇️

scientific article published on 06 June 2016

Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer ⬇️

scientific article published on 22 October 2015

Significant variation of resected meso-esophageal tissue volume in two-stage subtotal esophagectomy specimens: a retrospective morphometric study

scientific article published on 15 September 2012

Spatial profiling of gastric cancer patient-matched primary and locoregional metastases reveals principles of tumour dissemination

scientific article published on 23 November 2020

Technical reproducibility of single-nucleotide and size-based DNA biomarker assessment using DNA extracted from formalin-fixed, paraffin-embedded tissues

scientific article published on 4 March 2015

The proportion of tumour cells is an independent predictor for survival in colorectal cancer patients

scientific article

The septin-binding protein anillin is overexpressed in diverse human tumors

scientific article

The superiority of the seventh edition of the TNM classification depends on the overall survival of the patient cohort: comparative analysis of the sixth and seventh TNM editions in patients with gastric cancer from Japan and the United Kingdom.

scientific article published on 21 December 2012

The survival difference between gastric cancer patients from the UK and Japan remains after weighted propensity score analysis considering all background factors

scientific article

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