Search filters

List of works by Bissan Al-Lazikani

A HIF-regulated VHL-PTP1B-Src signaling axis identifies a therapeutic target in renal cell carcinoma

scientific article published on June 2011

A novel serum protein signature associated with resistance to epidermal growth factor receptor tyrosine kinase inhibitors in head and neck squamous cell carcinoma

scientific article published on 10 April 2013

Blocking the survival of the nastiest by HSP90 inhibition

scientific article

ChEMBL: a large-scale bioactivity database for drug discovery

scientific article (publication date: 2012)

Collation and data-mining of literature bioactivity data for drug discovery

scientific article

Combinatorial drug therapy for cancer in the post-genomic era.

scientific article

Combining multiple structure and sequence alignments to improve sequence detection and alignment: application to the SH2 domains of Janus kinases

scientific article

Defective acute inflammation in Crohn's disease: a clinical investigation

scientific article

Differences in Signaling Patterns on PI3K Inhibition Reveal Context Specificity in KRAS-Mutant Cancers

scientific article published on 01 July 2019

Distinctive Behaviors of Druggable Proteins in Cellular Networks

scientific article (publication date: December 2015)

Drugging cancer genomes

scientific article published in December 2013

Effective function annotation through catalytic residue conservation

scientific article

Genome-based cancer therapeutics: targets, kinase drug resistance and future strategies for precision oncology

scientific article published on 28 June 2013

Genomic-scale prioritization of drug targets: the TDR Targets database

scientific article

How many drug targets are there?

scientific article

JARID2 is a direct target of the PAX3-FOXO1 fusion protein and inhibits myogenic differentiation of rhabdomyosarcoma cells.

scientific article

JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer

scientific article published on 01 February 2021

Ligand efficiency indices for an effective mapping of chemico-biological space: the concept of an atlas-like representation.

scientific article published on 19 August 2010

Minimum information about a bioactive entity (MIABE).

scientific article

New open drug activity data at EBI

Objective assessment of cancer genes for drug discovery

article

Personalized cancer medicine: molecular diagnostics, predictive biomarkers, and drug resistance

scientific article

Personalized medicine: patient-predictive panel power

scientific article

Protein Structure Prediction

Public resources for chemical probes: the journey so far and the road ahead

scientific article published on 28 November 2019

SCOPEC: a database of protein catalytic domains.

scientific article

Sequence, structure and energetic determinants of phosphopeptide selectivity of SH2 domains

scientific article published in December 2003

Standard conformations for the canonical structures of immunoglobulins

scientific article

The Molecular Basis of Predicting Druggability

The complement of enzymatic sets in different species

scientific article

The genome of the blood fluke Schistosoma mansoni

scientific article

The kinase polypharmacology landscape of clinical PARP inhibitors

scientific article published on 17 February 2020

Therapeutic opportunities within the DNA damage response

scientific article

Transforming cancer drug discovery with Big Data and AI

scientific article published on 08 July 2019

Unpicking the combination lock for mutant BRAF and RAS melanomas.

scientific article

canSAR: an integrated cancer public translational research and drug discovery resource

scientific article

canSAR: an updated cancer research and drug discovery knowledgebase

scientific article published on 15 December 2015

canSAR: updated cancer research and drug discovery knowledgebase

scientific article published on 03 December 2013

Paulina is supported by:

About Paulina

Help