List of works - Imran Shah

A comparison of machine learning algorithms for chemical toxicity classification using a simulated multi-scale data model

scientific article

Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

scientific article

Bisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor-negative inflammatory breast cancer cells

scientific article

Building shared experience to advance practical application of pathway-based toxicology: liver toxicity mode-of-action

scientific article published on 28 January 2014

Computational toxicology--a state of the science mini review

scientific article published on 07 December 2007

Corrigendum: The BioPAX community standard for pathway data sharing

correction; published 7 December 2010

Current approaches and future role of high content imaging in safety sciences and drug discovery

scientific article published on 14 July 2014

Development of a quantitative model of pregnane X receptor (PXR) mediated xenobiotic metabolizing enzyme induction

scientific article

Development of an adverse outcome pathway from drug-mediated bile salt export pump inhibition to cholestatic liver injury

scientific article published on 14 August 2013

Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

scientific article

Exposure science and the U.S. EPA National Center for Computational Toxicology

scientific article

Generalized Read-Across prediction using genra-py

scientific article published in 2021

Genes Induced by Reovirus Infection Have a Distinct Modular Cis-Regulatory Architecture

scientific article published on January 2005

Heurstic search for metabolic engineering: de novo synthesis of vanillin

In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme

scientific article published on 22 April 2014

In vitro perturbations of targets in cancer hallmark processes predict rodent chemical carcinogenesis

scientific article

In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project

scientific article

Incorporating Biological, Chemical, and Toxicological Knowledge Into Predictive Models of Toxicity

article

Investigation of DUSP8 and CALCA in alcohol dependence

scientific article published in September 2003

PathMiner: predicting metabolic pathways by heuristic search

scientific article published on September 2003

Pathway-Based Approaches for Environmental Monitoring and Risk Assessment.

scientific article published in November 2016

Predicting hepatotoxicity using ToxCast in vitro bioactivity and chemical structure

scientific article published on 9 March 2015

Predicting organ toxicity using in vitro bioactivity data and chemical structure

scientific article

Quantitative prediction of repeat dose toxicity values using GenRA

scientific article published on 21 September 2019

Reproducibility and robustness of high-throughput S1500+ transcriptomics on primary rat hepatocytes for chemical-induced hepatotoxicity assessment

scientific article published on 05 August 2021

Simulating microdosimetry in a virtual hepatic lobule

scientific article

Simulating quantitative cellular responses using asynchronous threshold Boolean network ensembles

scientific article

Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information.

scientific article

Systems Toxicology: Real World Applications and Opportunities.

scientific article

Systems toxicology from genes to organs

scientific article published on January 2013

The BioPAX community standard for pathway data sharing

scientific article (publication date: September 2010)

The CompTox Chemistry Dashboard: a community data resource for environmental chemistry

scientific article

ToxCast: Predicting Toxicity Potential Through High-Throughput Bioactivity Profiling

article

Toxicokinetic Triage for Environmental Chemicals

scientific article

Using ToxCast™ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure

scientific article

Using nuclear receptor activity to stratify hepatocarcinogens

scientific article

Using pathway modules as targets for assay development in xenobiotic screening

scientific article

Virtual tissues in toxicology

scientific article published in February 2010

Visualization based on the Enzyme Commission nomenclature

scientific article

List of works by Imran Shah

A comparison of machine learning algorithms for chemical toxicity classification using a simulated multi-scale data model

Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

Bisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor-negative inflammatory breast cancer cells

Building shared experience to advance practical application of pathway-based toxicology: liver toxicity mode-of-action

Computational toxicology--a state of the science mini review

Corrigendum: The BioPAX community standard for pathway data sharing

Current approaches and future role of high content imaging in safety sciences and drug discovery

Development of a quantitative model of pregnane X receptor (PXR) mediated xenobiotic metabolizing enzyme induction

Development of an adverse outcome pathway from drug-mediated bile salt export pump inhibition to cholestatic liver injury

Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

Exposure science and the U.S. EPA National Center for Computational Toxicology

Generalized Read-Across prediction using genra-py

Genes Induced by Reovirus Infection Have a Distinct Modular Cis-Regulatory Architecture

Heurstic search for metabolic engineering: de novo synthesis of vanillin

In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme

In vitro perturbations of targets in cancer hallmark processes predict rodent chemical carcinogenesis

In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project

Incorporating Biological, Chemical, and Toxicological Knowledge Into Predictive Models of Toxicity

Investigation of DUSP8 and CALCA in alcohol dependence

PathMiner: predicting metabolic pathways by heuristic search

Pathway-Based Approaches for Environmental Monitoring and Risk Assessment.

Predicting hepatotoxicity using ToxCast in vitro bioactivity and chemical structure

Predicting organ toxicity using in vitro bioactivity data and chemical structure

Quantitative prediction of repeat dose toxicity values using GenRA

Reproducibility and robustness of high-throughput S1500+ transcriptomics on primary rat hepatocytes for chemical-induced hepatotoxicity assessment

Simulating microdosimetry in a virtual hepatic lobule

Simulating quantitative cellular responses using asynchronous threshold Boolean network ensembles

Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information.

Systems Toxicology: Real World Applications and Opportunities.

Systems toxicology from genes to organs

The BioPAX community standard for pathway data sharing

The CompTox Chemistry Dashboard: a community data resource for environmental chemistry

ToxCast: Predicting Toxicity Potential Through High-Throughput Bioactivity Profiling

Toxicokinetic Triage for Environmental Chemicals

Using ToxCast™ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure

Using nuclear receptor activity to stratify hepatocarcinogens

Using pathway modules as targets for assay development in xenobiotic screening

Virtual tissues in toxicology

Visualization based on the Enzyme Commission nomenclature