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List of works by David Bowtell

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International network of cancer genome projects

scientific article
ARID1A mutations in endometriosis-associated ovarian carcinomas

scientific article
Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome

scientific article
Rethinking ovarian cancer: recommendations for improving outcomes

scientific article
Whole-genome characterization of chemoresistant ovarian cancer

scientific article published in May 2015
BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group

scientific article
Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary

scientific article
Mutation ofFOXL2in Granulosa-Cell Tumors of the Ovary

scientific article published on 10 June 2009
Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors

scientific article
Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice

scientific article
Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer

scientific article
Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling

scientific article
Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

scientific article
The genesis and evolution of high-grade serous ovarian cancer

scientific article published on October 14, 2010
Options available--from start to finish--for obtaining expression data by microarray.

scientific article
The Hippo pathway transcriptional co-activator, YAP, is an ovarian cancer oncogene.

scientific article published on 14 February 2011
Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study

scientific article
Oncogenic pathway combinations predict clinical prognosis in gastric cancer.

scientific article published on 02 October 2009
Primary tumor hypoxia recruits CD11b+/Ly6Cmed/Ly6G+ immune suppressor cells and compromises NK cell cytotoxicity in the premetastatic niche.

scientific article
IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer

scientific article published on 22 February 2011
Siah2-dependent concerted activity of HIF and FoxA2 regulates formation of neuroendocrine phenotype and neuroendocrine prostate tumors

scientific article
Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas

scientific article published on 03 February 2009
Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma

scientific article published on 6 June 2017
Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma

scientific article
Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia

scientific article
Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer

scientific article published on 27 August 2015
A dynamic inflammatory cytokine network in the human ovarian cancer microenvironment

scientific article published on 7 November 2011
Differential expression of selected histone modifier genes in human solid cancers

scientific article published on 25 April 2006
Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion.

scientific article
Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers

scientific article
Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis

scientific article published on 26 August 2016
An expression-based site of origin diagnostic method designed for clinical application to cancer of unknown origin

scientific article
The changing view of high-grade serous ovarian cancer

scientific article
Options available--from start to finish--for obtaining data from DNA microarrays II.

scientific article
UV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell Carcinomas

scientific article published on 15 December 2015
Profiles of genomic instability in high-grade serous ovarian cancer predict treatment outcome

scientific article
High resolution melting for mutation scanning of TP53 exons 5-8

scientific article
Synthetic lethality between CCNE1 amplification and loss of BRCA1.

scientific article
Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population

scientific article published on 10 September 2015
A binding motif for Siah ubiquitin ligase.

scholarly article
The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity

scientific article
Distinctive patterns of gene expression in premalignant gastric mucosa and gastric cancer

article
Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling

scientific article
Molecular characterization of mucinous ovarian tumours supports a stratified treatment approach with HER2 targeting in 19% of carcinomas.

scientific article published in January 2013
SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer

scientific article
Stress-induced decrease in TRAF2 stability is mediated by Siah2

scientific article
Cyclin E1 deregulation occurs early in secretory cell transformation to promote formation of fallopian tube-derived high-grade serous ovarian cancers.

scientific article published on 23 December 2013
An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response.

scientific article
The ubiquitin ligase Siah2 regulates tumorigenesis and metastasis by HIF-dependent and -independent pathways

scholarly article
Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer.

scientific article published on 12 October 2017

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