List of works - Pedro José Barbosa Pereira

A simple linearization method unveils hidden enzymatic assay interferences

scientific article published on 29 May 2019

Accelerated Protein Synthesis via One-Pot Ligation-Deselenization Chemistry

Aprotinin binding to amyloid fibrils.

scientific article

Biochemical characterization of biliverdins IXβ/δ generated by a selective heme oxygenase

scientific article published on 01 February 2020

Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1--methyltransferase specific for 3--methylated mannosides

article published in the Proceedings of the National Academy of Sciences of the United States of America

Caspase-1 and IL-1β processing in a teleost fish

scientific article

Characterization of binding epitopes of CA125 monoclonal antibodies.

scientific article published on 4 June 2014

Cloning, purification and preliminary crystallographic studies of the 2AB protein from hepatitis A virus

scientific article published on 29 September 2011

Crystallization and preliminary crystallographic analysis of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus

scientific article published on 31 July 2008

Crystallization and preliminary crystallographic characterization of glutamine synthetase from Medicago truncatula

scientific article published on 27 November 2009

Crystallization and preliminary crystallographic characterization of the N-terminal Kunitz domain of boophilin

scientific article published on 27 March 2012

Crystallization and preliminary crystallographic characterization of three peptidic inhibitors in complex with α-thrombin

scientific article published on 21 December 2010

Data publication with the structural biology data grid supports live analysis

scientific article

Expression and functional characterization of boophilin, a thrombin inhibitor from Rhipicephalus (Boophilus) microplus midgut

scientific article published on 28 January 2012

Functional analyses yield detailed insight into the mechanism of thrombin inhibition by the antihemostatic salivary protein cE5 from Anopheles gambiae.

scientific article published on 7 June 2017

Functional and structural characterization of a novel mannosyl‐3‐phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity ⬇️

scientific article published on November 2, 2010

Functional and structural characterization of synthetic cardosin B-derived rennet

scientific article published on 2 August 2017

Genetic code ambiguity modulates the activity of a C. albicans MAP kinase linked to cell wall remodeling

scientific article published on 20 February 2019

Genome sequence of Mycobacterium hassiacum DSM 44199, a rare source of heat-stable mycobacterial proteins.

scientific article published on December 2012

High-resolution structure of a Kazal-type serine protease inhibitor from the dengue vector Aedes aegypti

scientific article published on 26 July 2017

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore

scientific article

Human procarboxypeptidase B: three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (TAFI)

scientific article

In silico and crystallographic studies identify key structural features of biliverdin IXβ reductase inhibitors having nanomolar potency.

scientific article published on 27 February 2018

In-house UV radiation-damage-induced phasing of selenomethionine-labeled protein structures

scientific article

Isolation, Cloning and Structural Characterisation of Boophilin, a Multifunctional Kunitz-Type Proteinase Inhibitor from the Cattle Tick

scientific article

Leech-derived thrombin inhibitors: from structures to mechanisms to clinical applications

scientific article published on May 2010

Molecular Fingerprints for a Novel Enzyme Family in with Glucosamine Kinase Activity

scientific article published on 14 May 2019

Molecular cloning and characterization of sea bass (Dicentrarchus labrax, L.) Tapasin

scientific article published on 18 November 2011

Molecular cloning and characterization of sea bass (Dicentrarchus labrax, L.) calreticulin

scientific article published on 22 March 2013

Molecular cloning and expression analysis of sea bass (Dicentrarchus labrax L.) tumor necrosis factor-alpha (TNF-alpha).

scientific article published on 24 February 2007

Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2.

scientific article published on 12 October 2017

Mosquito-Derived Anophelin Sulfoproteins Are Potent Antithrombotics

scientific article

Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis

scientific article

Octanoylation of early intermediates of mycobacterial methylglucose lipopolysaccharides

scientific journal article

Production, crystallization and structure determination of a mycobacterial glucosylglycerate hydrolase

scientific article

Protein crystals as a key for deciphering macromolecular crowding effects on biological reactions

scientific article published on 08 July 2020

Purification, crystallization and preliminary X-ray diffraction analysis of the seryl-tRNA synthetase from Candida albicans

scientific article published on 24 December 2010

Rapid assembly and profiling of an anticoagulant sulfoprotein library

scientific article published on 20 June 2019

SUMOylation of the brain-predominant Ataxin-3 isoform modulates its interaction with p97.

scientific article published on 11 June 2015

Selective albumin-binding surfaces modified with a thrombin-inhibiting peptide.

scientific article published on 5 December 2013

Ser or Leu: structural snapshots of mistranslation in Candida albicans.

scientific article published on 19 December 2014

Specific inhibition of insect alpha-amylases: yellow meal worm alpha-amylase in complex with the amaranth alpha-amylase inhibitor at 2.0 A resolution

scientific article

Structural basis for host membrane remodeling induced by protein 2B of hepatitis A virus

scientific article

Structure and Function of Human Chymase

Structure of human biliverdin IXbeta reductase, an early fetal bilirubin IXbeta producing enzyme

scientific article

Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway

scientific article (publication date: 26 January 2015)

The 2.2 A Crystal Structure of Human Chymase in Complex with Succinyl-Ala-Ala-Pro-Phe-chloromethylketone: Structural Explanation for its Dipeptidyl Carboxypeptidase Specificity

scientific article

The 2.2 A crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phe-chloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity

scientific article

The Tick-Derived Anticoagulant Madanin Is Processed by Thrombin and Factor Xa

scientific article

The binding of 2,4-dinitrophenol to wild-type and amyloidogenic transthyretin

scientific article published on 19 April 2006

The crystal and solution structures of glyceraldehyde-3-phosphate dehydrogenase reveal different quaternary structures

scientific article

The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors.

scientific article published on 6 October 2004

The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation

scientific article published on 08 May 2019

The structures of cytosolic and plastid-located glutamine synthetases fromMedicago truncatulareveal a common and dynamic architecture

scientific article

The unique regulation of iron-sulfur cluster biogenesis in a Gram-positive bacterium

scientific article

Tick-derived Kunitz-type inhibitors as antihemostatic factors

scientific article published on 24 July 2009

Transporters associated with antigen processing (TAP) in sea bass (Dicentrarchus labrax, L.): molecular cloning and characterization of TAP1 and TAP2.

scientific article published on 19 April 2011

Trifluoroethanethiol: an additive for efficient one-pot peptide ligation-desulfurization chemistry

scientific article published on 29 May 2014

Trypanosoma cruzi macrophage infectivity potentiator has a rotamase core and a highly exposed alpha-helix

scientific article

Two thioredoxin-superfamily members from sea bass (Dicentrarchus labrax, L.): characterization of PDI (PDIA1) and ERp57 (PDIA3).

scientific article published on 21 July 2013

Tyrosine sulfation modulates activity of tick-derived thrombin inhibitors

scientific article published on 20 March 2017

Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector

scientific article

Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen

scientific article

What a difference a cluster makes: The multifaceted roles of IscR in gene regulation and DNA recognition

scientific article

List of works by Pedro José Barbosa Pereira

A simple linearization method unveils hidden enzymatic assay interferences

Accelerated Protein Synthesis via One-Pot Ligation-Deselenization Chemistry

Aprotinin binding to amyloid fibrils.

Biochemical characterization of biliverdins IXβ/δ generated by a selective heme oxygenase

Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1--methyltransferase specific for 3--methylated mannosides

Caspase-1 and IL-1β processing in a teleost fish

Characterization of binding epitopes of CA125 monoclonal antibodies.

Cloning, purification and preliminary crystallographic studies of the 2AB protein from hepatitis A virus

Crystallization and preliminary crystallographic analysis of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus

Crystallization and preliminary crystallographic characterization of glutamine synthetase from Medicago truncatula

Crystallization and preliminary crystallographic characterization of the N-terminal Kunitz domain of boophilin

Crystallization and preliminary crystallographic characterization of three peptidic inhibitors in complex with α-thrombin

Data publication with the structural biology data grid supports live analysis

Expression and functional characterization of boophilin, a thrombin inhibitor from Rhipicephalus (Boophilus) microplus midgut

Functional analyses yield detailed insight into the mechanism of thrombin inhibition by the antihemostatic salivary protein cE5 from Anopheles gambiae.

Functional and structural characterization of a novel mannosyl‐3‐phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity ⬇️

Functional and structural characterization of synthetic cardosin B-derived rennet

Genetic code ambiguity modulates the activity of a C. albicans MAP kinase linked to cell wall remodeling

Genome sequence of Mycobacterium hassiacum DSM 44199, a rare source of heat-stable mycobacterial proteins.

High-resolution structure of a Kazal-type serine protease inhibitor from the dengue vector Aedes aegypti

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore

Human procarboxypeptidase B: three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (TAFI)

In silico and crystallographic studies identify key structural features of biliverdin IXβ reductase inhibitors having nanomolar potency.

In-house UV radiation-damage-induced phasing of selenomethionine-labeled protein structures

Isolation, Cloning and Structural Characterisation of Boophilin, a Multifunctional Kunitz-Type Proteinase Inhibitor from the Cattle Tick

Leech-derived thrombin inhibitors: from structures to mechanisms to clinical applications

Molecular Fingerprints for a Novel Enzyme Family in with Glucosamine Kinase Activity

Molecular cloning and characterization of sea bass (Dicentrarchus labrax, L.) Tapasin

Molecular cloning and characterization of sea bass (Dicentrarchus labrax, L.) calreticulin

Molecular cloning and expression analysis of sea bass (Dicentrarchus labrax L.) tumor necrosis factor-alpha (TNF-alpha).

Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2.

Mosquito-Derived Anophelin Sulfoproteins Are Potent Antithrombotics

Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis

Octanoylation of early intermediates of mycobacterial methylglucose lipopolysaccharides

Production, crystallization and structure determination of a mycobacterial glucosylglycerate hydrolase

Protein crystals as a key for deciphering macromolecular crowding effects on biological reactions

Purification, crystallization and preliminary X-ray diffraction analysis of the seryl-tRNA synthetase from Candida albicans

Rapid assembly and profiling of an anticoagulant sulfoprotein library

SUMOylation of the brain-predominant Ataxin-3 isoform modulates its interaction with p97.

Selective albumin-binding surfaces modified with a thrombin-inhibiting peptide.

Ser or Leu: structural snapshots of mistranslation in Candida albicans.

Specific inhibition of insect alpha-amylases: yellow meal worm alpha-amylase in complex with the amaranth alpha-amylase inhibitor at 2.0 A resolution

Structural basis for host membrane remodeling induced by protein 2B of hepatitis A virus

Structure and Function of Human Chymase

Structure of human biliverdin IXbeta reductase, an early fetal bilirubin IXbeta producing enzyme

Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway

The 2.2 A Crystal Structure of Human Chymase in Complex with Succinyl-Ala-Ala-Pro-Phe-chloromethylketone: Structural Explanation for its Dipeptidyl Carboxypeptidase Specificity

The 2.2 A crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phe-chloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity

The Tick-Derived Anticoagulant Madanin Is Processed by Thrombin and Factor Xa

The binding of 2,4-dinitrophenol to wild-type and amyloidogenic transthyretin

The crystal and solution structures of glyceraldehyde-3-phosphate dehydrogenase reveal different quaternary structures

The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors.

The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation

The structures of cytosolic and plastid-located glutamine synthetases fromMedicago truncatulareveal a common and dynamic architecture

The unique regulation of iron-sulfur cluster biogenesis in a Gram-positive bacterium

Tick-derived Kunitz-type inhibitors as antihemostatic factors

Transporters associated with antigen processing (TAP) in sea bass (Dicentrarchus labrax, L.): molecular cloning and characterization of TAP1 and TAP2.

Trifluoroethanethiol: an additive for efficient one-pot peptide ligation-desulfurization chemistry

Trypanosoma cruzi macrophage infectivity potentiator has a rotamase core and a highly exposed alpha-helix

Two thioredoxin-superfamily members from sea bass (Dicentrarchus labrax, L.): characterization of PDI (PDIA1) and ERp57 (PDIA3).

Tyrosine sulfation modulates activity of tick-derived thrombin inhibitors

Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector

Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen

What a difference a cluster makes: The multifaceted roles of IscR in gene regulation and DNA recognition

X-ray crystallographic studies of two transthyretin variants: further insights into amyloidogenesis