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List of works by Heinfried H. Radeke

A Comprehensive Assessment of Apigenin as an Antiproliferative, Proapoptotic, Antiangiogenic and Immunomodulatory Phytocompound

scientific article published on 16 April 2019

A rationally engineered anti-HIV peptide fusion inhibitor with greatly reduced immunogenicity

scientific article published on 12 November 2012

A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway

scientific article

Activation of autoreactive T-lymphocytes by cultured syngeneic glomerular mesangial cells.

scientific article published on March 1994

Activation-Induced Cell Death of Dendritic Cells Is Dependent on Sphingosine Kinase 1

scientific article published on 15 April 2016

Additive and synergistic effects of cyclosporine metabolites on glomerular mesangial cells

scientific article published on 01 June 1991

Adjuvant-guided type-1 and type-2 immunity: infectious/noninfectious dichotomy defines the class of response

scientific article published in April 1999

Analysis of immunoreactive and biologically active human parathyroid hormone-peptides by high-performance-liquid-chromatography

scientific article published in September 1984

Behaviour of four different B16 murine melanoma cell sublines: C57BL/6J skin

scientific article

Betulin - a plant-derived cytostatic drug - enhances antitumor immune response

article

Betulin silver nanoparticles qualify as efficient antimelanoma agents in in vitro and in vivo studies

scientific article published on 07 November 2018

Biglycan, a novel trigger of Th1 and Th17 cell recruitment into the kidney

scientific article published on 15 December 2017

Botanical Therapeutics: Phytochemical Screening and Biological Assessment of Chamomile, Parsley and Celery Extracts against A375 Human Melanoma and Dendritic Cells ⬇️

scientific article published on 16 November 2018

CD4+ T cells recognizing specific antigen deposited in glomeruli cause glomerulonephritis-like kidney injury

scientific article published in August 2002

CD40 ligand-triggered human dendritic cells mount interleukin-23 responses that are further enhanced by danger signals

scientific article

CXCL9 causes heterologous desensitization of CXCL12-mediated memory T lymphocyte activation.

scientific article published on 27 February 2013

Cancer-induced inflammation and inflammation-induced cancer in colon: a role for S1P lyase

scientific article published on 28 February 2019

Ceramide synthase 2 deficiency aggravates AOM-DSS-induced colitis in mice: role of colon barrier integrity.

scientific article published on 12 April 2017

Characterization of CXCL16 and ADAM10 in the normal and transplanted kidney

scientific article published on 14 May 2008

Computer-aided analysis of cell interactions under dynamic flow conditions.

scientific article published on 22 October 2008

Defective IL-23/IL-17 Axis Protects p47phox-/- Mice from Colon Cancer

scientific article published on 27 January 2017

Differential Expression of Mcp-1 and Its Receptor CCR2 in Glucose Primed Human Mesangial Cells

scientific article published in 2002

Differential biological activities of human interleukin-1 alpha and interleukin-1 beta

scientific article published on 01 January 1991

Early identification of interferon-beta responders by ex vivo testing in patients with multiple sclerosis

scientific article

Editorial: which iron preparation for patients with IBD? Authors' reply.

scientific article published in July 2017

Effects of cyclosporin and FK-506 on glomerular mesangial cells

scientific article published in January 1993

FTY720 ameliorates Th1-mediated colitis in mice by directly affecting the functional activity of CD4+CD25+ regulatory T cells.

scientific article

FTY720 ameliorates oxazolone colitis in mice by directly affecting T helper type 2 functions

scientific article

Fingolimod targeting protein phosphatase 2A differently affects IL-33 induced IL-2 and IFN-γ production in CD8(+) lymphocytes.

scientific article published on 18 December 2015

Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations

scientific article

High plasma sST2 levels in gastric cancer and their association with metastatic disease.

scientific article published on January 2016

High thioredoxin-1 levels in rheumatoid arthritis patients diminish binding and signalling of the monoclonal antibody Tregalizumab

scientific article published on 23 December 2016

Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-alpha.

scientific article published on October 1989

Human glomerular mesangial cells inactivate leukotriene B4 by reduction into dihydro-leukotriene B4 metabolites

scientific article published in January 1990

IFN-γ induces the high-affinity Fc receptor I for IgG (CD64) on human glomerular mesangial cells

scientific article published in September 1998

IFNgamma induces functional chemokine receptor expression in human mesangial cells

scientific article published in May 2002

Immune modulatory treatment of trinitrobenzene sulfonic acid colitis with calcitriol is associated with a change of a T helper (Th) 1/Th17 to a Th2 and regulatory T cell profile

scientific article

Immunomodulator FTY720 induces myofibroblast differentiation via the lysophospholipid receptor S1P3 and Smad3 signaling

scientific article published on January 2007

Immunomodulatory effects of 25-hydroxyvitamin D3 on monocytic cell differentiation and influence of vitamin D3 polymorphisms in type 1 diabetes.

scientific article published on 7 November 2014

Immunopharmacological activity of betulin in inflammation-associated carcinogenesis

scientific article published on 12 October 2017

Increased Serum Levels of the IL-33 Neutralizing sST2 in Limited Cutaneous Systemic Sclerosis

scientific article

Interference with MCP-1 gene expression by vector generated triple helix-forming RNA oligonucleotides.

scientific article

Interferon-Beta Increases Plasma Ceramides of Specific Chain Length in Multiple Sclerosis Patients, Unlike Fingolimod or Natalizumab.

scientific article

Interleukin-1 beta and tumor necrosis factor-alpha synergistically stimulate nerve growth factor synthesis in rat mesangial cells

scientific article published in November 1991

Isolation of an immunosuppressive metabolite of FK506 generated by human microsome preparations

scientific article published in June 1991

Isolation of two immunosuppressive metabolites after in vitro metabolism of rapamycin ⬇️

scientific article published on March 1, 1992

Junctional adhesion molecule (JAM)-B supports lymphocyte rolling and adhesion through interaction with alpha4beta1 integrin

scientific article published in October 2009

Junctional adhesion molecules (JAM)-B and -C contribute to leukocyte extravasation to the skin and mediate cutaneous inflammation

scientific article

LC–MS/MS determination of FTY720 and FTY720-phosphate in murine intracellular compartments and human plasma ⬇️

scientific article published on January 30, 2012

Letter: inconsistency in reporting of hypophosphataemia after intravenous iron-authors' reply

scientific article published in September 2017

Letter: the importance of dosing and baseline haemoglobin when establishing the relative efficacy of intravenous iron therapies-authors' reply.

scientific article

Lymphocyte-derived cytokines induce sequential expression of monocyte- and T cell-specific chemokines in human mesangial cells

scientific article published in December 1997

Management of inflammatory bowel disease-related anemia and iron deficiency with specific reference to the role of intravenous iron in current practice.

scientific article published on 11 October 2017

Mechanisms of Inflammation: Symposium of the Sonderforschungsbereich (SFB 244), Hannover, Germany, 4–5 June 1998

scientific article published in November 1998

Modulation of IL-33/ST2-TIR and TLR signalling pathway by fingolimod and analogues in immune cells

scientific article published on December 2014

Modulation of glomerular mesangial cell growth and prostaglandin release by T-lymphocyte products

scientific article published in January 1991

Monokines and platelet-derived growth factor modulate prostanoid production in growth arrested, human mesangial cells

scientific article published on 01 March 1990

Multiple pre- and postreceptor defects in pseudohypoparathyroidism (a multicenter study with twenty four patients).

scientific article published in February 1986

Multivariate analyses of immune reconstitution in children after allo-SCT: risk-estimation based on age-matched leukocyte sub-populations

scientific article published on 24 August 2009

Mycophenolate mofetil inhibits rat and human mesangial cell proliferation by guanosine depletion.

scientific article published in January 1999

Ncf1 provides a reactive oxygen species-independent negative feedback regulation of TLR9-induced IL-12p70 in murine dendritic cells

scientific article published in April 2009

Novel approach to specific growth factor inhibition in vivo: antagonism of platelet-derived growth factor in glomerulonephritis by aptamers.

scientific article published on January 1999

NoxO1 Controls Proliferation of Colon Epithelial Cells.

scientific article

Nuclear Translocation of SGPP-1 and Decrease of SGPL-1 Activity Contribute to Sphingolipid Rheostat Regulation of Inflammatory Dendritic Cells.

scientific article

Opposite Regulation of Type II and III Receptors for Immunoglobulin G in Mouse Glomerular Mesangial Cells and in the Induction of Anti-glomerular Basement Membrane (GBM) Nephritis

scientific article published in Journal of Biological Chemistry

PS3, a semisynthetic beta-1,3-glucan sulfate, diminishes contact hypersensitivity responses through inhibition of L- and P-selectin functions.

scientific article published on 4 December 2008

Platelet, not endothelial, P-selectin expression contributes to generation of immunity in cutaneous contact hypersensitivity

scientific article published on 7 January 2010

Posttranslational modification of the AU-rich element binding protein HuR by protein kinase Cdelta elicits angiotensin II-induced stabilization and nuclear export of cyclooxygenase 2 mRNA

scientific journal article

Prediction of acute renal allograft rejection by urinary monokine induced by IFN-gamma (MIG).

scientific article published on 27 April 2005

Prostaglandin E2 production is synergistically increased in cultured human glomerular mesangial cells by combinations of IL-1 and tumor necrosis factor-alpha 1

scientific article published on 15 September 1989

Protein kinase C alpha-dependent phosphorylation of the mRNA-stabilizing factor HuR: implications for posttranscriptional regulation of cyclooxygenase-2

scientific journal article

Response to comment on "CXCL9 causes heterologous desensitization of CXCL12-mediated memory T lymphocyte activation".

scientific article published in July 2013

S1P Lyase siRNA Dampens Malignancy of DLD-1 Colorectal Cancer Cells

scientific article published on 24 September 2020

Selective inhibition of monocyte chemoattractant protein-1 gene expression in human embryonal kidney cells by specific triple helix-forming oligonucleotides.

scientific article published on February 2000

Sensorineural hearing loss owing to deficient G proteins in patients with pseudohypoparathyroidism: results of a multicentre study

scientific article published in August 1990

Serum miR-122 as a biomarker of necroinflammation in patients with chronic hepatitis C virus infection

scientific article

Serum microRNA-21 as marker for necroinflammation in hepatitis C patients with and without hepatocellular carcinoma

scientific article

Simultaneous and dose dependent melanoma cytotoxic and immune stimulatory activity of betulin

scientific article

Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-beta-induced cell responses

scientific article

Sphingosine 1-phosphate modulates antigen capture by murine Langerhans cells via the S1P2 receptor subtype

scientific article

Sphingosine kinase 2 is a negative regulator of inflammatory macrophage activation

scientific article published on 23 May 2019

Sphingosine-1-Phosphate Receptor 5 Modulates Early-Stage Processes during Fibrogenesis in a Mouse Model of Systemic Sclerosis: A Pilot Study

scientific article published on 29 September 2017

Subcellular distribution of FTY720 and FTY720-phosphate in immune cells - another aspect of Fingolimod action relevant for therapeutic application.

scientific article published on June 2015

Systematic review with network meta-analysis: comparative efficacy and tolerability of different intravenous iron formulations for the treatment of iron deficiency anaemia in patients with inflammatory bowel disease.

scientific article

TLR-ligand stimulated interleukin-23 subunit expression and assembly is regulated differentially in murine plasmacytoid and myeloid dendritic cells.

scientific article published on 18 October 2006

Tetrahydrobiopterin Attenuates DSS-evoked Colitis in Mice by Rebalancing Redox and Lipid Signalling

scientific article published on 29 February 2016

The inflammatory function of renal glomerular mesangial cells and their interaction with the cellular immune system

scientific article published on September 1, 1992

The new low calcemic vitamin D analog 22-ene-25-oxa-vitamin D prominently ameliorates T helper cell type 1-mediated colitis in mice

scientific article

The sphingosine kinase 1 and S1P1 axis specifically counteracts LPS-induced IL-12p70 production in immune cells of the spleen.

scientific article published on 23 March 2011

The synergistic immunosuppressive potential of cyclosporin metabolite combinations

scientific article published on May 1, 1992

Tissue Cytokine IL-33 Modulates the Cytotoxic CD8 T Lymphocyte Activity During Nutrient Deprivation by Regulation of Lineage-Specific Differentiation Programs

scientific article published on 24 July 2019

Upregulation of group IB secreted phospholipase A(2) and its M-type receptor in rat ANTI-THY-1 glomerulonephritis.

scientific article

[Activation-dependent expression of Fc gamma-receptors on glomerular mesangial cells]

scientific article published in April 1995

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