List of works - Michel O Steinmetz

13C, 15N Resonance Assignment of Parts of the HET-s Prion Protein in its Amyloid Form

A Correlative Analysis of Actin Filament Assembly, Structure, and Dynamics ⬇️

scientific article published on August 11, 1997

A Proteome-wide screen for mammalian SxIP motif-containing microtubule plus-end tracking proteins

scientific article

A conserved trimerization motif controls the topology of short coiled coils

scientific article

A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin.

scientific article

A missense mutation in the PISA domain of HsSAS-6 causes autosomal recessive primary microcephaly in a large consanguineous Pakistani family

scientific article

A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs

scientific article

A structural model for microtubule minus-end recognition and protection by CAMSAP proteins

scientific article published on 9 October 2017

Actin-microtubule coordination at growing microtubule ends

scientific article

Actin: Dissecting the Structural Basis of Its Oligomerization, Polymerization, and Polymorphism

scientific article published on 01 June 1998

An EB1-binding motif acts as a microtubule tip localization signal

scientific article

Antivascular and antitumor properties of the tubulin-binding chalcone TUB091

scientific article

Association of the leukocyte plasma membrane with the actin cytoskeleton through coiled coil-mediated trimeric coronin 1 molecules

scientific article

Atomic models of de novo designed cc beta-Met amyloid-like fibrils

scientific article published on 5 December 2007

Author Correction: A structural model for microtubule minus-end recognition and protection by CAMSAP proteins

scientific article published on 30 April 2020

Automated seamless DNA co-transformation cloning with direct expression vectors applying positive or negative insert selection.

scientific article

Automated unrestricted multigene recombineering for multiprotein complex production

scientific article published on 3 May 2009

Biophysical and Structural Characterization of the Centriolar Protein Cep104 Interaction Network

scientific article published on 8 July 2016

COMP-Ang1: a designed angiopoietin-1 variant with nonleaky angiogenic activity

scholarly article

Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry

scientific article

Capturing protein tails by CAP-Gly domains

scientific article published on 04 October 2008

Centriolar CPAP/SAS-4 Imparts Slow Processive Microtubule Growth

scientific article published on May 2016

Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent

scientific article published on October 2017

Configurational entropy elucidates the role of salt-bridge networks in protein thermostability.

scientific article

Conformational Properties of the Chemotherapeutic Drug Analogue Epothilone A: How to Model a Flexible Protein Ligand Using Scarcely Available Experimental Data

scientific article published on 25 March 2019

Control of intrinsically disordered stathmin by multisite phosphorylation.

scientific article

Control of microtubule organization and dynamics: two ends in the limelight

scientific article

Cooperative stabilization of microtubule dynamics by EB1 and CLIP-170 involves displacement of stably bound P(i) at microtubule ends.

scientific article published on 28 March 2012

Corrigendum: SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture

scientific article published in May 2016

Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies

scientific article published on 10 May 2016

Crystallization and Preliminary X-Ray Diffraction Analysis of the 190-Å-Long Coiled-Coil Dimerization Domain of the Actin-Bundling Protein Cortexillin I fromDictyostelium discoideum

Data-collection strategy for challenging native SAD phasing

scientific article

De novo design of a two-stranded coiled-coil switch peptide

scientific article published on 20 May 2006

Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention

scientific article

Drosophila stathmins bind tubulin heterodimers with high and variable stoichiometries

scientific article

EB1 interacts with outwardly curved and straight regions of the microtubule lattice

scientific article published on 12 September 2016

ELM--the database of eukaryotic linear motifs

scientific article

End binding proteins are obligatory dimers

scientific article

End-binding proteins sensitize microtubules to the action of microtubule-targeting agents

scientific article published on 14 May 2013

Erratum: Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex.

scientific article published in June 2017

Exploring amyloid formation by a de novo design

scholarly article

Exploring the Conserved Water Site and Hydration of a Coiled‐Coil Trimerisation Motif: A MD Simulation Study

scientific article published on 01 July 2008

Exploring the trigger sequence of the GCN4 coiled-coil: Biased molecular dynamics resolves apparent inconsistencies in NMR measurements

scientific article

Fast native-SAD phasing for routine macromolecular structure determination

scientific article

High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design.

scientific article published on 9 March 2018

High-level expression and purification of a designed angiopoietin-1 chimeric protein, COMP-Ang1, produced in Chinese hamster ovary cells.

scientific article published in August 2008

Identification of Chlamydomonas Central Core Centriolar Proteins Reveals a Role for Human WDR90 in Ciliogenesis.

scientific article

Imaging biological matter across dimensions: from cells to molecules and atoms.

scientific article

In vitro reconstitution of dynamic microtubules interacting with actin filament networks

scientific article published on January 2014

In vitro reconstitution of the functional interplay between MCAK and EB3 at microtubule plus ends

scientific article published on 16 September 2010

Influence of 63Ser phosphorylation and dephosphorylation on the structure of the stathmin helical nucleation sequence: a molecular dynamics study.

scientific article published on 10 October 2012

Influence of the effector peptide of MARCKS-related protein on actin polymerization: a kinetic analysis

article

Insights into EB1 structure and the role of its C-terminal domain for discriminating microtubule tips from the lattice

scientific article

Insights into Peroxisome Function from the Structure of PEX3 in Complex with a Soluble Fragment of PEX19

scientific article

Interaction between actin and the effector peptide of MARCKS-related protein. Identification of functional amino acid segments.

scientific article

Interaction of mammalian end binding proteins with CAP-Gly domains of CLIP-170 and p150(glued)

scientific article

Isolation, Electron Microscopic Imaging, and 3-D Visualization of Native Cardiac Thin Myofilaments

scholarly article by Martin Spiess et al published June 1999 in Journal of Structural Biology

Key interaction modes of dynamic +TIP networks

scientific article published in September 2006

Kinesin-4 KIF21B is a potent microtubule pausing factor.

scientific article published on 14 March 2017

Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity.

scientific article published on 2 March 2016

Laminin chain assembly is regulated by specific coiled-coil interactions

scientific article

Localizing Chemical Groups while Imaging Single Native Proteins by High-Resolution Atomic Force Microscopy

scientific article published on 05 May 2014

MARCKS-Related Protein Binds to Actin without Significantly Affecting Actin Polymerization or Network Structure

Mammalian end binding proteins control persistent microtubule growth

scientific article

Methods of NMR structure refinement: molecular dynamics simulations improve the agreement with measured NMR data of a C-terminal peptide of GCN4-p1.

scientific article

Microtubule +TIPs at a glance

scientific article published on October 2010

Microtubule End Binding: EBs Sense the Guanine Nucleotide State

Microtubule minus-end regulation at a glance

scientific article published on 07 June 2019

Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex

scientific article

Molecular basis of Kar9-Bim1 complex function during mating and spindle positioning

scientific article published on 28 September 2016

Molecular basis of coiled-coil formation

scientific article

Molecular basis of coiled-coil oligomerization-state specificity

scientific article

Molecular insights into mammalian end-binding protein heterodimerization

scientific article

Molecular mechanism of action of microtubule-stabilizing anticancer agents

scientific article

Molecular-Dynamics Simulations of C- and N-Terminal Peptide Derivatives of GCN4-p1 in Aqueous Solution

article

Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates.

scientific article published on September 2007

Multivalency ensures persistence of a +TIP body at specialized microtubule ends

Native architecture of the centriole proximal region reveals features underlying its 9-fold radial symmetry

scientific article published on 8 August 2013

Oligomerization and multimerization are critical for angiopoietin-1 to bind and phosphorylate Tie2.

scientific article

Op18/stathmin caps a kinked protofilament-like tubulin tetramer

scientific article

Optochemistry to control the microtubule cytoskeleton

scientific article published on 17 July 2015

Pironetin Binds Covalently to αCys316 and Perturbs a Major Loop and Helix of α-Tubulin to Inhibit Microtubule Formation

scientific article

Polymorphism in an Amyloid‐Like Fibril‐Forming Model Peptide

article

Probing the Structure and Dynamics of Proteins by Combining Molecular Dynamics Simulations and Experimental NMR Data.

scientific article published on 30 July 2012

Production of in vitro amplified DNA pseudolibraries and high-throughput cDNA target amplification

scientific article

Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure.

scientific article

Quinolin-6-Yloxyacetamides Are Microtubule Destabilizing Agents That Bind to the Colchicine Site of Tubulin.

scientific article published on 22 June 2017

Rat GTP cyclohydrolase I is a homodecameric protein complex containing high-affinity calcium-binding sites

scientific journal article

Reconstitution of a hierarchical +TIP interaction network controlling microtubule end tracking of dynein

scientific article published on 6 July 2014

Regulation of microtubule dynamic instability in vitro by differentially phosphorylated stathmin.

scientific article published on 08 April 2009

SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture

scientific article

SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase

scientific article

STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER.

scientific article

Sequence determinants of a microtubule tip localization signal (MtLS).

scientific article

Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons

scientific article

Short Linear Sequence Motif LxxPTPh Targets Diverse Proteins to Growing Microtubule Ends

scientific article published on 22 May 2017

Solid-state NMR spectroscopy reveals that E. coli inclusion bodies of HET-s(218-289) are amyloids

scientific article

Structural Basis for the Oligomerization-State Switch from a Dimer to a Trimer of an Engineered Cortexillin-1 Coiled-Coil Variant

scientific article

Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics

scientific article

Structural Basis of Microtubule Stabilization by Discodermolide.

scientific article published on 16 February 2017

Structural Basis of the 9-Fold Symmetry of Centrioles

scientific article

Structural basis for misregulation of kinesin KIF21A autoinhibition by CFEOM1 disease mutations

scientific article published on 03 August 2016

Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A

scientific article

Structural basis for the regulation of tubulin by vinblastine

scientific article published in May 2005

Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis

scientific article

Structural basis of katanin p60:p80 complex formation.

scientific article published on 2 November 2017

Structural basis of microtubule stabilization by laulimalide and peloruside A

scientific article

Structural basis of tubulin detyrosination by the vasohibin-SVBP enzyme complex

scientific article published on 24 June 2019

Structural basis of tubulin tyrosination by tubulin tyrosine ligase

scientific article

Structural determinants of microtubule minus end preference in CAMSAP CKK domains

scientific article published on 20 November 2019

Structural insights into the EB1-APC interaction

scientific article

Structural insights into the EB1–APC interaction

scholarly article by Srinivas Honnappa published in February 2005

Structure and thermodynamics of the tubulin-stathmin interaction

scientific article

Structure of a VEGF-VEGF receptor complex determined by electron microscopy

scientific article published on 11 February 2007

Structure of the Extracellular Domain of Tie Receptor Tyrosine Kinases and Localization of the Angiopoietin-binding Epitope

scientific article published in Journal of Biological Chemistry

Structure-function relationship of CAP-Gly domains

scientific article

Suppression of microtubule dynamic instability by the +TIP protein EB1 and its modulation by the CAP-Gly domain of p150glued

scientific article published on 15 December 2007

Surface tensiometry of phase separated protein and polymer droplets by the sessile drop method

scientific article published on 23 December 2020

Sustainable Syntheses of (-)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site.

scientific article published on 13 July 2018

Taxanes convert regions of perturbed microtubule growth into rescue sites

scientific article published on 09 December 2019

Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes

scientific article

The Caenorhabditis elegans septin complex is nonpolar

scientific article published on 28 June 2007

The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding

scientific article

The novel microtubule-destabilizing drug BAL27862 binds to the colchicine site of tubulin with distinct effects on microtubule organization

scientific article

The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity.

scientific article

Thermodynamics of the Op18/stathmin-tubulin interaction

scientific journal article

Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin

scientific article

Tyrosine-dependent capture of CAP-Gly domain-containing proteins in complex mixture by EB1 C-terminal peptidic probes

scientific article published on 21 April 2012

List of works by Michel O Steinmetz

13C, 15N Resonance Assignment of Parts of the HET-s Prion Protein in its Amyloid Form

A Correlative Analysis of Actin Filament Assembly, Structure, and Dynamics ⬇️

A Proteome-wide screen for mammalian SxIP motif-containing microtubule plus-end tracking proteins

A conserved trimerization motif controls the topology of short coiled coils

A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin.

A missense mutation in the PISA domain of HsSAS-6 causes autosomal recessive primary microcephaly in a large consanguineous Pakistani family

A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs

A structural model for microtubule minus-end recognition and protection by CAMSAP proteins

Actin-microtubule coordination at growing microtubule ends

Actin: Dissecting the Structural Basis of Its Oligomerization, Polymerization, and Polymorphism

An EB1-binding motif acts as a microtubule tip localization signal

Antivascular and antitumor properties of the tubulin-binding chalcone TUB091

Association of the leukocyte plasma membrane with the actin cytoskeleton through coiled coil-mediated trimeric coronin 1 molecules

Atomic models of de novo designed cc beta-Met amyloid-like fibrils

Author Correction: A structural model for microtubule minus-end recognition and protection by CAMSAP proteins

Automated seamless DNA co-transformation cloning with direct expression vectors applying positive or negative insert selection.

Automated unrestricted multigene recombineering for multiprotein complex production

Biophysical and Structural Characterization of the Centriolar Protein Cep104 Interaction Network

COMP-Ang1: a designed angiopoietin-1 variant with nonleaky angiogenic activity

Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry

Capturing protein tails by CAP-Gly domains

Centriolar CPAP/SAS-4 Imparts Slow Processive Microtubule Growth

Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent

Configurational entropy elucidates the role of salt-bridge networks in protein thermostability.

Conformational Properties of the Chemotherapeutic Drug Analogue Epothilone A: How to Model a Flexible Protein Ligand Using Scarcely Available Experimental Data

Control of intrinsically disordered stathmin by multisite phosphorylation.

Control of microtubule organization and dynamics: two ends in the limelight

Cooperative stabilization of microtubule dynamics by EB1 and CLIP-170 involves displacement of stably bound P(i) at microtubule ends.

Corrigendum: SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture

Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies

Crystallization and Preliminary X-Ray Diffraction Analysis of the 190-Å-Long Coiled-Coil Dimerization Domain of the Actin-Bundling Protein Cortexillin I fromDictyostelium discoideum

Data-collection strategy for challenging native SAD phasing

De novo design of a two-stranded coiled-coil switch peptide

Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention

Drosophila stathmins bind tubulin heterodimers with high and variable stoichiometries

EB1 interacts with outwardly curved and straight regions of the microtubule lattice

ELM--the database of eukaryotic linear motifs

End binding proteins are obligatory dimers

End-binding proteins sensitize microtubules to the action of microtubule-targeting agents

Erratum: Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex.

Exploring amyloid formation by a de novo design

Exploring the Conserved Water Site and Hydration of a Coiled‐Coil Trimerisation Motif: A MD Simulation Study

Exploring the trigger sequence of the GCN4 coiled-coil: Biased molecular dynamics resolves apparent inconsistencies in NMR measurements

Fast native-SAD phasing for routine macromolecular structure determination

High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design.

High-level expression and purification of a designed angiopoietin-1 chimeric protein, COMP-Ang1, produced in Chinese hamster ovary cells.

Identification of Chlamydomonas Central Core Centriolar Proteins Reveals a Role for Human WDR90 in Ciliogenesis.

Imaging biological matter across dimensions: from cells to molecules and atoms.

In vitro reconstitution of dynamic microtubules interacting with actin filament networks

In vitro reconstitution of the functional interplay between MCAK and EB3 at microtubule plus ends

Influence of 63Ser phosphorylation and dephosphorylation on the structure of the stathmin helical nucleation sequence: a molecular dynamics study.

Influence of the effector peptide of MARCKS-related protein on actin polymerization: a kinetic analysis

Insights into EB1 structure and the role of its C-terminal domain for discriminating microtubule tips from the lattice

Insights into Peroxisome Function from the Structure of PEX3 in Complex with a Soluble Fragment of PEX19

Interaction between actin and the effector peptide of MARCKS-related protein. Identification of functional amino acid segments.

Interaction of mammalian end binding proteins with CAP-Gly domains of CLIP-170 and p150(glued)

Isolation, Electron Microscopic Imaging, and 3-D Visualization of Native Cardiac Thin Myofilaments

Key interaction modes of dynamic +TIP networks

Kinesin-4 KIF21B is a potent microtubule pausing factor.

Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity.

Laminin chain assembly is regulated by specific coiled-coil interactions

Localizing Chemical Groups while Imaging Single Native Proteins by High-Resolution Atomic Force Microscopy

MARCKS-Related Protein Binds to Actin without Significantly Affecting Actin Polymerization or Network Structure

Mammalian end binding proteins control persistent microtubule growth

Methods of NMR structure refinement: molecular dynamics simulations improve the agreement with measured NMR data of a C-terminal peptide of GCN4-p1.

Microtubule +TIPs at a glance

Microtubule End Binding: EBs Sense the Guanine Nucleotide State

Microtubule minus-end regulation at a glance

Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex

Molecular basis of Kar9-Bim1 complex function during mating and spindle positioning

Molecular basis of coiled-coil formation

Molecular basis of coiled-coil oligomerization-state specificity

Molecular insights into mammalian end-binding protein heterodimerization

Molecular mechanism of action of microtubule-stabilizing anticancer agents

Molecular-Dynamics Simulations of C- and N-Terminal Peptide Derivatives of GCN4-p1 in Aqueous Solution

Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates.

Multivalency ensures persistence of a +TIP body at specialized microtubule ends

Native architecture of the centriole proximal region reveals features underlying its 9-fold radial symmetry

Oligomerization and multimerization are critical for angiopoietin-1 to bind and phosphorylate Tie2.