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Authors whose works are in public domain in at least one jurisdiction

List of works by Matthew Meyerson

A Candidate Cell-Selective Anticancer Agent

A Functional Landscape of Resistance to MEK1/2 and CDK4/6 Inhibition in NRAS-Mutant Melanoma

scientific article published on 28 February 2019

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1

scientific article

A functional landscape of resistance to ALK inhibition in lung cancer

scientific article

A landscape of driver mutations in melanoma

scientific article

A novel totivirus and piscine reovirus (PRV) in Atlantic salmon (Salmo salar) with cardiomyopathy syndrome (CMS).

scientific article

A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events

scientific article published on 31 January 2014

A rapid and sensitive enzymatic method for epidermal growth factor receptor mutation screening

scientific article

A structure-guided approach to creating covalent FGFR inhibitors

scientific article

Absolute quantification of somatic DNA alterations in human cancer

scientific article

Abstract 2169: New telomeres and chromosomal arm fusions in cancer genomes revealed by long-read genome sequencing

scientific article published in 2022

Abstract 3890: Sequencing of 888 pediatric solid tumors informs precision oncology trial design and data sharing initiatives in pediatric cancer

scientific article published in 2022

Abstract 4036: Frequent downregulation of the transcription factor Foxa2 in lung cancer through epigenetic silencing

article

Acquired resistance to dasatinib in lung cancer cell lines conferred by DDR2 gatekeeper mutation and NF1 loss

scientific article published on 02 December 2013

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

scientific article (publication date: April 2005)

Activating mutations in ALK provide a therapeutic target in neuroblastoma

scientific article

Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia

scientific article

Activation of GATA binding protein 6 (GATA6) sustains oncogenic lineage-survival in esophageal adenocarcinoma

scientific article published on 28 February 2012

Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors

scientific article published on 27 September 2013

Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

scientific article published on 01 January 2019

Adding pathogens by genomic subtraction

scientific article

Advances in understanding cancer genomes through second-generation sequencing ⬇️

scientific article (publication date: October 2010)

Allele-Specific Amplification in Cancer Revealed by SNP Array Analysis

scientific article published on 31 October 2005

Allele-dependent variation in the relative cellular potency of distinct EGFR inhibitors

scientific article published on 13 February 2007

Allele-specific amplification in cancer revealed by SNP array analysis

scientific article

Amplification of CRKL induces transformation and epidermal growth factor receptor inhibitor resistance in human non-small cell lung cancers

scientific article

Amplification of chromosomal segment 4q12 in non-small cell lung cancer

scientific article

Amplification of phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.

scientific article published in June 2012

An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells

scientific article

An alternative inhibitor overcomes resistance caused by a mutation of the epidermal growth factor receptor.

scientific article published on August 2005

An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays

scientific article published on May 2004

Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer.

scientific article

Assessing prognosis in non-small-cell lung cancer: avenues to a more complete picture?

scientific article published on 12 July 2004

Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma

scientific article (publication date: 11 December 2007)

Association of Alterations in Main Driver Genes With Outcomes of Patients With Resected Pancreatic Ductal Adenocarcinoma

scientific article

Author Correction: Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells

correction of a scholarly article

Author Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes

article

Autophosphorylation of the C-terminal domain is not required for oncogenic transformation by lung-cancer derived EGFR mutants

scientific article published on 21 February 2018

BRAF alteration status and the histone H3F3A gene K27M mutation segregate spinal cord astrocytoma histology

scientific article published on 20 October 2015

Bacterial invaders drive CRC progression

scientific article published on 11 August 2020

Bradyrhizobium enterica in cord colitis syndrome

scientific article published in November 2013

BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers

scientific article

Breaking down RET breakpoints in lung adenocarcinoma

scientific article published on May 2014

Broken genes in solid tumours

scientific article published in Nature

Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy

scientific article

C/EBPα mutations in lung cancer

scientific article published on 12 June 2006

CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity

scientific article

Calibrating genomic and allelic coverage bias in single-cell sequencing

scientific article published on 16 April 2015

Cancer genomes evolve by pulverizing single chromosomes

scientific article published on 01 January 2011

Cetuximab response of lung cancer-derived EGF receptor mutants is associated with asymmetric dimerization

scientific article published on 24 September 2013

Characterization of DDR2 Inhibitors for the Treatment of DDR2 Mutated Nonsmall Cell Lung Cancer

scientific article

Characterization of HPV and host genome interactions in primary head and neck cancers

scientific article

Characterizing the cancer genome in lung adenocarcinoma

scientific article

Chromosomal deletions and progression of premalignant lesions: less is more

scientific article published on 01 November 2008

Chromothripsis from DNA damage in micronuclei.

scientific article

Circulating Tumor DNA Provides a Sneak Peek into Treatment Responses in Non-Small Cell Lung Cancer

scientific article published on 01 March 2019

Clinical Implementation of Comprehensive Strategies to Characterize Cancer Genomes: Opportunities and Challenges ⬇️

scientific article published on September 1, 2011

Clinical significance of TTF-1 protein expression and TTF-1 gene amplification in lung adenocarcinoma

scientific article

Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke

scientific article

Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab

scientific article

Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency

scientific article

Combined tumor and immune signals from genomes or transcriptomes predict outcomes of checkpoint inhibition in melanoma

scientific article published in 2022

Commensal Microbiota Promote Lung Cancer Development via γδ T Cells

scientific article published on 31 January 2019

Comment on "The consensus coding sequences of human breast and colorectal cancers".

scientific article

Comparison of Prevalence and Types of Mutations in Lung Cancers Among Black and White Populations

scientific article published on 19 January 2017

Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case

scientific article published on October 2015

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

scientific article

Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

scientific article published on 01 August 2018

Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma

scientific article published on 4 November 2015

Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma

scientific article

Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma

article

Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors

scientific article published on 23 January 2014

Comprehensive metagenomic analysis of blastic plasmacytoid dendritic cell neoplasm

scientific article published on 01 March 2020

Copy number alterations unmasked as enhancer hijackers

scientific article

Correction: Functional Genomic Analysis of <i>CDK4</i> and <i>CDK6</i> Gene Dependency across Human Cancer Cell Lines

scientific article published in 2022

Correction: Inferring Loss-of-Heterozygosity from Unpaired Tumors Using High-Density Oligonucleotide SNP Arrays.

scientific article published on 23 February 2007

Correction: Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12

scientific article published on 01 November 2020

Correction: Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples

Correction: Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples.

scientific article published in September 2010

Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth

scientific article published on 30 June 2017

Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth

scientific article published on 24 June 2016

DNA copy number analysis of metastatic urothelial carcinoma with comparison to primary tumors

scientific article published on 9 April 2015

DNA sequencing of cancer: what have we learned?

scientific article

Detection of Somatic Structural Variants Enables Quantification and Characterization of Circulating Tumor DNA in Children With Solid Tumors

scientific article published on 05 July 2018

Discovering the anti-cancer potential of non-oncology drugs by systematic viability profiling

scientific article published on 20 January 2020

Discovery and saturation analysis of cancer genes across 21 tumour types

scientific article

Dissecting the genomic complexity underlying medulloblastoma

scientific article

Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling

scientific article

Distinct Pathways Affected by Menin versus MLL1/MLL2 in MLL-rearranged Acute Myeloid Leukemia

scientific article published on 10 October 2018

Distinct genomic aberrations associated with ERG rearranged prostate cancer

scientific article published on April 2009

Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells

scientific article published on August 2013

Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

scientific article

Drug-sensitive FGFR2 mutations in endometrial carcinoma

scholarly article

Dynamic epigenetic regulation by menin during pancreatic islet tumor formation

scientific article published on 23 December 2014

EGFR gene mutations: a call for global x global views of cancer

scientific article published on 01 March 2005

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

scientific article

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

scientific article

EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing

scientific article

EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer

scientific article

ERG rearrangement is specific to prostate cancer and does not occur in any other common tumor

scientific article published on 14 May 2010

Emerging Concepts and Technologies for the Discovery of Microorganisms Involved in Human Disease

scientific article published on 5 December 2016

Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain

scientific article

Epidermal growth factor receptor mutation testing in the care of lung cancer patients

scientific article published on July 2006

Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors

scholarly article

Epidermal growth factor-independent transformation of Ba/F3 cells with cancer-derived epidermal growth factor receptor mutants induces gefitinib-sensitive cell cycle progression

scientific article

Erratum to “Pathogen discovery from human tissue by sequence-based computational subtraction”

scholarly article published in Genomics

Erratum: Corrigendum: High-throughput oncogene mutation profiling in human cancer

article

Erratum: Corrigendum: Signatures of mutational processes in human cancer

scientific article published in Nature

Evolution and impact of subclonal mutations in chronic lymphocytic leukemia

scientific article published on February 2013

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

scientific article

Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences

scientific article

Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib

scientific article

Focal gains of VEGFA and molecular classification of hepatocellular carcinoma

scientific article published on August 2008

Frequent HIN-1 promoter methylation and lack of expression in multiple human tumor types

scientific article

Frequent downregulation of the transcription factor Foxa2 in lung cancer through epigenetic silencing

scientific article

Functional Genomic Analysis of <i>CDK4</i> and <i>CDK6</i> Gene Dependency across Human Cancer Cell Lines

scientific article published in 2022

Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2.

scientific article

Functional copy-number alterations in cancer

scientific article

Fusobacterium nucleatum in Colorectal Cancer Relates to Immune Response Differentially by Tumor Microsatellite Instability Status

scientific article published on 18 September 2018

Fusobacterium nucleatum in Colorectal Carcinoma Tissue According to Tumor Location

scientific article

Fusobacterium nucleatum in colorectal carcinoma tissue and patient prognosis

scientific article published on 26 August 2015

Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor-immune microenvironment

scientific article

GATK PathSeq: a customizable computational tool for the discovery and identification of microbial sequences in libraries from eukaryotic hosts

scientific article published in December 2018

GE-17ALTERATION OF THE p53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA.

scientific article published in November 2014

GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

scientific article published on 28 April 2011

Ganetespib (STA-9090), a nongeldanamycin HSP90 inhibitor, has potent antitumor activity in in vitro and in vivo models of non-small cell lung cancer.

scientific article

Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis

scientific article

Gefitinib induces apoptosis in the EGFRL858R non-small-cell lung cancer cell line H3255.

scientific article

Gene expression profiling reveals reproducible human lung adenocarcinoma subtypes in multiple independent patient cohorts

scientific article published on November 2006

Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study

scientific article

Genetic ancestry contributes to somatic mutations in lung cancers from admixed Latin American populations

scientific article published on 02 December 2020

Genetic and transcriptional evolution alters cancer cell line drug response

scientific article published in August 2018

Genetic interrogation of circulating multiple myeloma cells at single-cell resolution

scientific article

Genetic modifiers of EGFR dependence in non-small cell lung cancer

scientific article

Genome coverage and sequence fidelity of phi29 polymerase-based multiple strand displacement whole genome amplification

scientific article

Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer

scientific article published on 28 June 2018

Genome-wide analysis of neuroblastomas using high-density single nucleotide polymorphism arrays

scientific article published on 28 February 2007

Genome-wide association study in esophageal squamous cell carcinoma

scientific article published on 27 September 2009

Genome-wide loss of heterozygosity analysis from laser capture microdissected prostate cancer using single nucleotide polymorphic allele (SNP) arrays and a novel bioinformatics platform dChipSNP.

scientific article

Genomic Activation of PPARG Reveals a Candidate Therapeutic Axis in Bladder Cancer

scientific article published on 18 September 2017

Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets

scientific article published on 26 September 2015

Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting

scientific article published on 3 June 2016

Genomic Profiling of Prostate Cancers from Men with African and European Ancestry

scientific article published on 10 July 2020

Genomic aberrations in cervical adenocarcinomas in Hong Kong Chinese women

scientific article published on 13 February 2015

Genomic analysis identifies association of Fusobacterium with colorectal carcinoma

scientific article

Genomic and Functional Approaches to Understanding Cancer Aneuploidy

scientific article published on 31 March 2018

Genomic and immune profiling of pre-invasive lung adenocarcinoma

scientific article published on 29 November 2019

Genomic and proteomic profiling of lung cancers: lung cancer classification in the age of targeted therapy

scientific article

Genomic approaches to lung cancer

scientific article published on July 2006

Genomic basis for RNA alterations in cancer

scientific article published on 05 February 2020

Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer types

Genomic discovery and clonal tracking in multiple myeloma by cell-free DNA sequencing

scientific article published on 27 March 2018

Genomic representations using concatenates of Type IIB restriction endonuclease digestion fragments

scientific article

Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion

scientific article published on 04 September 2011

Genotype-targeted local therapy of glioma

scientific article published on 06 August 2018

Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas

scientific article published on 9 November 2016

Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer

article

Glioblastoma-derived epidermal growth factor receptor carboxyl-terminal deletion mutants are transforming and are sensitive to EGFR-directed therapies

scientific article published on 14 October 2011

HER-2/neu expression is associated with high tumor cell proliferation and aggressive phenotype in a population based patient series of endometrial carcinomas

scientific article published on 01 February 2008

HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy

scientific article

Haplotype-resolved germline and somatic alterations in renal medullary carcinomas

scientific article published on 14 July 2021

High order chromatin architecture shapes the landscape of chromosomal alterations in cancer

scientific article published on 20 November 2011

High-resolution mapping of copy-number alterations with massively parallel sequencing

scientific article

High-resolution single-nucleotide polymorphism array and clustering analysis of loss of heterozygosity in human lung cancer cell lines

scientific article published on April 2004

High-throughput Phenotyping of Lung Cancer Somatic Mutations

scientific article published on 28 July 2016

High-throughput Phenotyping of Lung Cancer Somatic Mutations

scientific article published in December 2017

High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing

scientific article

High-throughput oncogene mutation profiling in human cancer

article

High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia

scientific article published on 5 February 2008

Highly parallel identification of essential genes in cancer cells

scholarly article

Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis

scientific article published on July 2005

Hopping between differentiation states in lung adenocarcinoma

scientific article published on June 2013

Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance

scientific article

Human genetic variation and disease

scientific article published on July 2003

ICGC PedBrain - dissecting the genomic complexity underlying medulloblastoma using whole-genome sequencing

scientific article

Identification and Characterization of Oncogenic SOS1 Mutations in Lung Adenocarcinoma

scientific article published on 11 January 2019

Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells

scientific article published in Nature Communications

Identification of an "Exceptional Responder" Cell Line to MEK1 Inhibition: Clinical Implications for MEK-Targeted Therapy

scientific article published on 18 November 2015

Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics.

scientific article

Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers

scientific article

Identification of foreign gene sequences by transcript filtering against the human genome

scientific article

Identifying and characterizing a novel activating mutation of the FLT3 tyrosine kinase in AML.

scientific article

In Situ Evidence of KRAS Amplification and Association With Increased p21 Levels in Non–Small Cell Lung Carcinoma

article

In search of a candidate pathogen for giant cell arteritis: sequencing-based characterization of the giant cell arteritis microbiome

scientific article

In search of human proteins and infectious triggers involved in periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome

scientific article published on 28 September 2015

Inferring Loss-of-Heterozygosity from Tumors Without Paired Normals Using High-Density SNP Arrays

scientific article published on 17 March 2006

Inferring loss-of-heterozygosity from unpaired tumors using high-density oligonucleotide SNP arrays

scientific article

Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer

scientific article

Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma

scientific article published on 20 June 2013

Initial genome sequencing and analysis of multiple myeloma

scientific article

Insertions and Deletions Target Lineage-Defining Genes in Human Cancers

scientific article

Institutional implementation of clinical tumor profiling on an unselected cancer population

scientific article published on 17 November 2016

Integrated Molecular Characterization of Testicular Germ Cell Tumors

article by Hui Shen et al published 12 June 2018 in Cell Reports

Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target

scientific article published on 15 January 2013

Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas

scientific article published on 03 February 2009

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

scientific article

Integrative analysis of the melanoma transcriptome

scientific article

Integrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients

scientific article

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

scientific article

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

scientific article (publication date: 7 July 2005)

Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome

scientific article

Integrative genomic approaches identify IKBKE as a breast cancer oncogene

scientific article published in June 2007

Integrative radiogenomic profiling of squamous cell lung cancer

scientific article published on 26 August 2013

Interlaboratory comparability study of cancer gene expression analysis using oligonucleotide microarrays.

scientific article published on January 2005

Kinase domain activation of FGFR2 yields high-grade lung adenocarcinoma sensitive to a Pan-FGFR inhibitor in a mouse model of NSCLC

scientific article

Kmt2a cooperates with menin to suppress tumorigenesis in mouse pancreatic islets

scientific article

Landscape of genomic alterations in cervical carcinomas

scientific article

Landscapes of childhood tumours

scientific article published in Nature

Lin28 promotes transformation and is associated with advanced human malignancies

scientific article published on 31 May 2009

Long-read sequencing reveals complex patterns of wraparound transcription in polyomaviruses

scientific article published on 01 April 2022

Loss of heterozygosity and its correlation with expression profiles in subclasses of invasive breast cancers

scientific article published on January 2004

Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1

scientific article

MET Exon 14 Mutation Encodes an Actionable Therapeutic Target in Lung Adenocarcinoma

scientific article published on 18 May 2017

Major copy proportion analysis of tumor samples using SNP arrays

scientific article

Making sense of cancer genomic data

scientific article

Making sense of cancer genomic data

Malawi polyomavirus is a prevalent human virus that interacts with known tumor suppressors

scientific article

Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing

scientific article

Massively parallel sequencing of formalin-fixed paraffin-embedded tissues

Mechanistic Insights into Transmissible Cancers of Mammals

scientific article published in April 2018

Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12

scientific article published on 31 January 2020

Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

scientific article (publication date: 22 July 2012)

Melanoma genome sequencing reveals frequent PREX2 mutations

scientific article

Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors

scientific article

Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus

scientific article

Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c

scientific journal article

Metagenomic Characterization of Microbial Communities In Situ Within the Deeper Layers of the Ileum in Crohn's Disease

scientific article published on 26 May 2016

Microbes and inflammation in colorectal cancer

scientific article

Missense mutations of the BRAF gene in human lung adenocarcinoma.

scientific article published in December 2002

Modeling genomic diversity and tumor dependency in malignant melanoma

scientific article published on February 2008

Molecular Characterization and Therapeutic Targeting of Colorectal Cancers Harboring Receptor Tyrosine Kinase Fusions

scientific article published on 07 January 2021

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

scientific article published on January 2016

Molecular classification and molecular genetics of human lung cancers

scientific article published on February 2004

Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes

article

Multi-Omics Analysis Identifies MGA as a Negative Regulator of the MYC Pathway in Lung Adenocarcinoma

scientific article published on 20 December 2019

Mutational heterogeneity in cancer and the search for new cancer-associated genes

scientific article

Mutational processes shape the landscape of TP53 mutations in human cancer.

scientific article

Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli

scientific article published on 27 February 2020

Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer

scientific article

NSCLC Driven by DDR2 Mutation Is Sensitive to Dasatinib and JQ1 Combination Therapy

scientific article published on 23 July 2015

Near universal detection of alterations in CTNNB1 and Wnt pathway regulators in desmoid-type fibromatosis by whole-exome sequencing and genomic analysis

scientific article

Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma

scientific article published on 21 March 2013

Non-small-cell lung cancer and Ba/F3 transformed cells harboring the ERBB2 G776insV_G/C mutation are sensitive to the dual-specific epidermal growth factor receptor and ERBB2 inhibitor HKI-272.

scientific article published on July 2006

Noncanonical junctions in subgenomic RNAs of SARS-CoV-2 lead to variant open reading frames

scientific article published on 30 April 2020

Nuclear factor I/B is an oncogene in small cell lung cancer

scientific article

Oncogenic RIT1 mutations in lung adenocarcinoma

scientific article

Oncogenic Signaling Pathways in The Cancer Genome Atlas

scientific article published in April 2018

Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma

scientific article

Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants

scientific article

Oncotator: cancer variant annotation tool

scientific article published on 16 March 2015

Optimization of PDE3A Modulators for SLFN12-Dependent Cancer Cell Killing

scientific article published on 18 October 2019

PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib

scientific article published on December 2007

PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR

scientific article (publication date: 15 April 2009)

Pan-cancer patterns of somatic copy number alteration

scientific article published on October 2013

PathSeq: software to identify or discover microbes by deep sequencing of human tissue

scientific article

Pathogen discovery from human tissue by sequence-based computational subtraction

scientific article published in March 2003

Pathogen discovery in AIDS-related lymphoma by high-throughput sequencing

article

Patient-derived lung cancer organoids as in vitro cancer models for therapeutic screening

scientific article published on 05 September 2019

Patterns of chromosome 18 loss of heterozygosity in multifocal ileal neuroendocrine tumors

scientific article published on 14 April 2020

Patterns of gene expression and copy-number alterations in von-hippel lindau disease-associated and sporadic clear cell carcinoma of the kidney

scientific article published on June 2009

Patterns of structural variation define prostate cancer across disease states

scientific article published in 2022

Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2

scientific article published on 01 December 2020

Phase II clinical trial of chemotherapy-naive patients > or = 70 years of age treated with erlotinib for advanced non-small-cell lung cancer

scientific article published on 16 January 2007

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

scientific article

Phosphorylation of the menin tumor suppressor protein on serine 543 and serine 583

scientific article published on 01 October 2006

Pivotal role of mTOR signaling in hepatocellular carcinoma

scientific article published on 20 August 2008

Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer

scientific article published on 28 August 2019

Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions

scientific article published on 18 May 2009

Predicting relapse in patients with medulloblastoma by integrating evidence from clinical and genomic features

scientific article

Profiling critical cancer gene mutations in clinical tumor samples

scientific article

Prognostic Impact of Novel Molecular Subtypes of Small Intestinal Neuroendocrine Tumor

scientific article published on 13 July 2015

Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small-cell lung cancer

scientific article

Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

scientific article

Prospective derivation of a living organoid biobank of colorectal cancer patients.

scientific article published on May 2015

Publisher Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes

article

Pugh et al. reply

scientific article published in Nature

Punctuated evolution of prostate cancer genomes

scientific article published on April 2013

Quantification of aneuploidy in targeted sequencing data using ASCETS

scientific article published on 28 November 2020

RAS-MAPK reactivation facilitates acquired resistance in FGFR1-amplified lung cancer and underlies a rationale for upfront FGFR-MEK blockade

scientific article published on 13 April 2018

ROS1 rearrangements in lung cancer: a new genomic subset of lung adenocarcinoma

scientific article

Rapid Intraoperative Molecular Characterization of Glioma

scientific article published on 14 May 2015

Recurrent BRAF mutations in Langerhans cell histiocytosis

scientific article

Recurrent and functional regulatory mutations in breast cancer

scientific article published on 28 June 2017

Recurrent hemizygous deletions in cancers may optimize proliferative potential

scientific article

Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth

scientific article published on 10 May 2016

Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence

scientific article published on 10 May 2021

Response to treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing

scientific article published on 01 January 2007

SF3B1 and other novel cancer genes in chronic lymphocytic leukemia

scientific article

SHP2 tyrosine phosphatase converts parafibromin/Cdc73 from a tumor suppressor to an oncogenic driver

scientific article published on July 2011

SOS1 mutations are rare in human malignancies: implications for Noonan Syndrome patients

scientific article published on March 2008

SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas

scientific article published on 03 March 2014

SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer

article

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas ⬇️

scientific article

Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors.

scientific article published on 6 November 2017

Sensitive detection of minimal residual disease in patients treated for early-stage breast cancer

scientific article published on 13 March 2020

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

scientific article

Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing

scientific article published on 25 June 2006

Sequence analysis of mutations and translocations across breast cancer subtypes

scientific article

Sequence-based discovery of Bradyrhizobium enterica in cord colitis syndrome

scientific article

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

scholarly article

Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor

scientific article

Signatures of mutational processes in human cancer

scientific article (publication date: 22 August 2013)

Somatic Superenhancer Duplications and Hotspot Mutations Lead to Oncogenic Activation of the KLF5 Transcription Factor.

scientific article published on 29 September 2017

Somatic alterations in the human cancer genome

scientific article

Somatic mutation of CDKN1B in small intestine neuroendocrine tumors

scientific article published on 3 November 2013

Somatic mutations affect key pathways in lung adenocarcinoma

scientific article

Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability

scientific article published on 2 November 2012

Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing

scientific article

Splicing modulation sensitizes chronic lymphocytic leukemia cells to venetoclax by remodeling mitochondrial apoptotic dependencies

scientific article published on 04 October 2018

Sporadic hemangioblastomas are characterized by cryptic VHL inactivation

scientific article

Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing

scientific article published on 18 June 2018

Structural, Biochemical, and Clinical Characterization of Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations in Lung Cancer

scientific article

Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6

scientific article published on 17 August 2015

Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase

scientific article published on 16 July 2021

Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity

scientific article

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

scientific article

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy

scientific article

Summary statement: novel agents in the treatment of lung cancer: advances in epidermal growth factor receptor-targeted agents

scientific article

Suppression of Adaptive Responses to Targeted Cancer Therapy by Transcriptional Repression.

scientific article

Suppression of lung adenocarcinoma progression by Nkx2-1

scientific article

SvABA: genome-wide detection of structural variants and indels by local assembly.

scientific article published on 13 March 2018

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

scientific article (publication date: 5 November 2009)

Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

scientific article

THE P53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA.

scientific article published in July 2014

TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer

scientific article published on September 2006

TTF1 expression in non-small cell lung carcinoma: association with TTF1 gene amplification and improved survival

scientific article published in January 2009

Targeted Therapy for Squamous Cell Lung Cancer ⬇️

scientific article published on December 1, 2012

Targeted genomic rearrangements using CRISPR/Cas technology

scientific article published on 24 April 2014

The Amount of Bifidobacterium Genus in Colorectal Carcinoma Tissue in Relation to Tumor Characteristics and Clinical Outcome

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The Somatic Genomic Landscape of Glioblastoma

article

The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP

scientific article

The genetic landscape of high-risk neuroblastoma

scientific article published on 20 January 2013

The genomic complexity of primary human prostate cancer

scientific article

The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor

scientific article published on 11 March 2008

The landscape of somatic copy-number alteration across human cancers

scientific article

The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis

scientific article published on October 2005

The menin tumor suppressor protein is phosphorylated in response to DNA damage

scientific article

The multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3' processing and transcription termination

scientific article

The parafibromin tumor suppressor protein is part of a human Paf1 complex

scientific article

The somatic genomic landscape of chromophobe renal cell carcinoma

scientific article (publication date: 8 September 2014)

The somatic genomic landscape of glioblastoma

scientific article

The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors

scientific article

The tumor virus landscape of AIDS-related lymphomas

scientific article published on 31 March 2015

Therapeutic targeting of oncogenic K-Ras by a covalent catalytic site inhibitor

scientific article published on 20 November 2013

Transcriptional activators enhance polyadenylation of mRNA precursors

scientific article

Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signaling

scientific article published on December 2006

Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia

scientific article published on 28 October 2016

Tumor fraction in cell-free DNA as a biomarker in prostate cancer

scientific article published on 02 November 2018

Unique, dual-indexed sequencing adapters with UMIs effectively eliminate index cross-talk and significantly improve sensitivity of massively parallel sequencing

scientific article published on 8 January 2018

Unusual cases in multiple myeloma and a dramatic response in metastatic lung cancer: case 4. Mutation of the epidermal growth factor receptor in an elderly man with advanced, gefitinib-responsive, non-small-cell lung cancer

scientific article published in January 2005

Updated Frequency of EGFR and KRAS Mutations in NonSmall-Cell Lung Cancer in Latin America: The Latin-American Consortium for the Investigation of Lung Cancer (CLICaP).

scientific article published in May 2015

VariantBam: filtering and profiling of next-generational sequencing data using region-specific rules

scientific article

Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development

scientific article

Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors

scientific article

Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer

scientific article

Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma

scientific article

Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution

scientific article

Whole-genome characterization of lung adenocarcinomas lacking the RTK/RAS/RAF pathway

scientific article published on 2 February 2021

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