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List of works by Hui Yang

A Cas-embedding strategy for minimizing off-target effects of DNA base editors

scientific article published on 27 November 2020

A dual inhibition: microRNA-552 suppresses both transcription and translation of cytochrome P450 2E1.

scientific article

A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects

scientific article published on 18 May 2020

Base editing-mediated splicing correction therapy for spinal muscular atrophy

scientific article published on 24 March 2020

CRISPR/Cas9 - Mediated Precise Targeted Integration In Vivo Using a Double Cut Donor with Short Homology Arms

scientific article

CRISPR/Cas9-mediated targeted chromosome elimination

scientific article published on 24 November 2017

Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos

scientific article published on 01 March 2019

Defects in Trophoblast Cell Lineage Account for the Impaired In Vivo Development of Cloned Embryos Generated by Somatic Nuclear Transfer ⬇️

scientific article published on April 8, 2011

Different developmental potential of pluripotent stem cells generated by different reprogramming strategies ⬇️

scientific article published on June 1, 2011

GOTI, a method to identify genome-wide off-target effects of genome editing in mouse embryos

scientific article published on 14 August 2020

Gene-edited babies: What went wrong and what could go wrong

article

Generating genetically modified mice using CRISPR/Cas-mediated genome engineering

scientific article published on 24 July 2014

Generation of Genetically Modified Mice by Oocyte Injection of Androgenetic Haploid Embryonic Stem Cells ⬇️

scientific article published on April 27, 2012

Generation of haploid embryonic stem cells from Macaca fascicularis monkey parthenotes

scientific article published on 16 July 2013

Haploid embryonic stem cells: an ideal tool for mammalian genetic analyses ⬇️

scientific article published on September 28, 2012

High-efficiency somatic reprogramming induced by intact MII oocytes

scientific article published on 6 July 2010

Highly efficient base editing in human tripronuclear zygotes

scientific article

Homology-mediated end joining-based targeted integration using CRISPR/Cas9.

scientific article

In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR-dCas9-activator transgenic mice.

scientific article published on 15 January 2018

Mice generated after round spermatid injection into haploid two-cell blastomeres ⬇️

scientific article published on March 22, 2011

Modulation of metabolic functions through Cas13d-mediated gene knockdown in liver

scientific article published on 18 March 2020

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

scientific article published on 27 August 2013

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering ⬇️

scientific article (publication date: 9 May 2013)

One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs

scientific article

One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering

scientific article published on 29 August 2013

Rescue of autosomal dominant hearing loss by in vivo delivery of mini dCas13X-derived RNA base editor

scientific article published in 2022

The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

scientific journal article

Treatment of autosomal recessive hearing loss via in vivo CRISPR/Cas9-mediated optimized homology-directed repair in mice

scientific article published in 2022

Zscan4 promotes genomic stability during reprogramming and dramatically improves the quality of iPS cells as demonstrated by tetraploid complementation ⬇️

scientific article published on November 13, 2012

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