List of works - Allen M Samarel

A protein kinase Cepsilon-anti-apoptotic kinase signaling complex protects human vascular endothelial cells against apoptosis through induction of Bcl-2.

scientific article published on 4 September 2007

Alterations in protein kinase C isoenzyme expression and autophosphorylation during the progression of pressure overload-induced left ventricular hypertrophy

scientific article published on 01 January 2003

An anticancer C-Kit kinase inhibitor is reengineered to make it more active and less cardiotoxic

scientific article

Beta(1)-integrins modulate beta-adrenergic receptor signaling

scientific article published in June 2004

CapZ dynamics are altered by endothelin-1 and phenylephrine via PIP2- and PKC-dependent mechanisms.

scientific article

Chronic fluoxetine reduces autonomic control of cardiac rhythms in rats with congestive heart failure.

scientific article

Contractile Activity Regulates Inducible Nitric Oxide Synthase Expression and NO(i) Production in Cardiomyocytes via a FAK-Dependent Signaling Pathway

scientific article published on 26 July 2012

Costameres, focal adhesions, and cardiomyocyte mechanotransduction.

scientific article

Deoxycholic acid differentially regulates focal adhesion kinase phosphorylation: role of tyrosine phosphatase ShP2.

scientific article published on 17 August 2006

Detection of differentially methylated gene promoters in failing and nonfailing human left ventricle myocardium using computation analysis.

scientific article published on 21 May 2013

Distinct pathways regulate expression of cardiac electrical and mechanical junction proteins in response to stretch.

scientific article published on 21 July 2005

FRNK inhibition of focal adhesion kinase-dependent signaling and migration in vascular smooth muscle cells.

scientific article published on 12 August 2010

Fibronectin fragment activation of proline-rich tyrosine kinase PYK2 mediates integrin signals regulating collagenase-3 expression by human chondrocytes through a protein kinase C-dependent pathway

scientific article

Focal Adhesion Kinase–Related Nonkinase Inhibits Vascular Smooth Muscle Cell Invasion by Focal Adhesion Targeting, Tyrosine 168 Phosphorylation, and Competition for p130 Cas Binding ⬇️

scientific article published on November 1, 2011

GFP-FRNK disrupts focal adhesions and induces anoikis in neonatal rat ventricular myocytes.

scientific article

IGF-1 Overexpression rescues the failing heart

scientific article published on 01 April 2002

Microdomain heterogeneity in 3D affects the mechanics of neonatal cardiac myocyte contraction.

scientific article

PKCepsilon induces astrocyte stellation by modulating multiple cytoskeletal proteins and interacting with Rho A signalling pathways: implications for neuroinflammation.

scientific article

PYK2 expression and phosphorylation increases in pressure overload-induced left ventricular hypertrophy.

scientific article

Persistent alterations in heart rate variability, baroreflex sensitivity, and anxiety-like behaviors during development of heart failure in the rat.

scientific article

Phorbol ester and endothelin-1 alter functional expression of Na+/Ca2+ exchange, K+, and Ca2+ currents in cultured neonatal rat myocytes

scientific article

Phosphorylation and binding of AUF1 to the 3'-untranslated region of cardiomyocyte SERCA2a mRNA

scientific journal article

Protein kinase C epsilon-dependent activation of proline-rich tyrosine kinase 2 in neonatal rat ventricular myocytes.

scientific article published on September 2003

Protein kinase C-epsilon activation induces mitochondrial dysfunction and fragmentation in renal proximal tubules

scientific article

Protein kinase Cepsilon-dependent MARCKS phosphorylation in neonatal and adult rat ventricular myocytes

scientific article published on 8 December 2006

Protein kinase Cε activity induces anti-inflammatory and anti-apoptotic genes via an ERK1/2- and NF-κB-dependent pathway to enhance vascular protection.

scientific article

Regulation of Connective Tissue Growth Factor Gene Expression and Fibrosis in Human Heart Failure ⬇️

scientific article published on March 19, 2013

Role of FRNK tyrosine phosphorylation in vascular smooth muscle spreading and migration.

scientific article

Serine-910 phosphorylation of focal adhesion kinase is critical for sarcomere reorganization in cardiomyocyte hypertrophy ⬇️

scientific article published on September 21, 2011

Syndecan-4: a component of the mechanosensory apparatus of cardiac fibroblasts.

scientific article published on 21 December 2012

Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.

scientific article

Targeted myocardial transgenic expression of HIV Tat causes cardiomyopathy and mitochondrial damage.

scientific article published in May 2002

Thymidine kinase and mtDNA depletion in human cardiomyopathy: epigenetic and translational evidence for energy starvation

scientific article published on 21 May 2013

Ursodeoxycholic acid suppresses Cox-2 expression in colon cancer: roles of Ras, p38, and CCAAT/enhancer-binding protein.

scientific article published in May 2008

List of works by Allen M Samarel

A protein kinase Cepsilon-anti-apoptotic kinase signaling complex protects human vascular endothelial cells against apoptosis through induction of Bcl-2.

Alterations in protein kinase C isoenzyme expression and autophosphorylation during the progression of pressure overload-induced left ventricular hypertrophy

An anticancer C-Kit kinase inhibitor is reengineered to make it more active and less cardiotoxic

Beta(1)-integrins modulate beta-adrenergic receptor signaling

CapZ dynamics are altered by endothelin-1 and phenylephrine via PIP2- and PKC-dependent mechanisms.

Chronic fluoxetine reduces autonomic control of cardiac rhythms in rats with congestive heart failure.

Contractile Activity Regulates Inducible Nitric Oxide Synthase Expression and NO(i) Production in Cardiomyocytes via a FAK-Dependent Signaling Pathway

Costameres, focal adhesions, and cardiomyocyte mechanotransduction.

Deoxycholic acid differentially regulates focal adhesion kinase phosphorylation: role of tyrosine phosphatase ShP2.

Detection of differentially methylated gene promoters in failing and nonfailing human left ventricle myocardium using computation analysis.

Distinct pathways regulate expression of cardiac electrical and mechanical junction proteins in response to stretch.

FRNK inhibition of focal adhesion kinase-dependent signaling and migration in vascular smooth muscle cells.

Fibronectin fragment activation of proline-rich tyrosine kinase PYK2 mediates integrin signals regulating collagenase-3 expression by human chondrocytes through a protein kinase C-dependent pathway

Focal Adhesion Kinase–Related Nonkinase Inhibits Vascular Smooth Muscle Cell Invasion by Focal Adhesion Targeting, Tyrosine 168 Phosphorylation, and Competition for p130 Cas Binding ⬇️

GFP-FRNK disrupts focal adhesions and induces anoikis in neonatal rat ventricular myocytes.

IGF-1 Overexpression rescues the failing heart

Microdomain heterogeneity in 3D affects the mechanics of neonatal cardiac myocyte contraction.

PKCepsilon induces astrocyte stellation by modulating multiple cytoskeletal proteins and interacting with Rho A signalling pathways: implications for neuroinflammation.

PYK2 expression and phosphorylation increases in pressure overload-induced left ventricular hypertrophy.

Persistent alterations in heart rate variability, baroreflex sensitivity, and anxiety-like behaviors during development of heart failure in the rat.

Phorbol ester and endothelin-1 alter functional expression of Na+/Ca2+ exchange, K+, and Ca2+ currents in cultured neonatal rat myocytes

Phosphorylation and binding of AUF1 to the 3'-untranslated region of cardiomyocyte SERCA2a mRNA

Protein kinase C epsilon-dependent activation of proline-rich tyrosine kinase 2 in neonatal rat ventricular myocytes.

Protein kinase C-epsilon activation induces mitochondrial dysfunction and fragmentation in renal proximal tubules

Protein kinase Cepsilon-dependent MARCKS phosphorylation in neonatal and adult rat ventricular myocytes

Protein kinase Cε activity induces anti-inflammatory and anti-apoptotic genes via an ERK1/2- and NF-κB-dependent pathway to enhance vascular protection.

Regulation of Connective Tissue Growth Factor Gene Expression and Fibrosis in Human Heart Failure ⬇️

Role of FRNK tyrosine phosphorylation in vascular smooth muscle spreading and migration.

Serine-910 phosphorylation of focal adhesion kinase is critical for sarcomere reorganization in cardiomyocyte hypertrophy ⬇️

Syndecan-4: a component of the mechanosensory apparatus of cardiac fibroblasts.

Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.

Targeted myocardial transgenic expression of HIV Tat causes cardiomyopathy and mitochondrial damage.

Thymidine kinase and mtDNA depletion in human cardiomyopathy: epigenetic and translational evidence for energy starvation

Ursodeoxycholic acid suppresses Cox-2 expression in colon cancer: roles of Ras, p38, and CCAAT/enhancer-binding protein.