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List of works by Andrew P. Feinberg

"Gap hunting" to characterize clustered probe signals in Illumina methylation array data

scientific article

A 2.5-Mb Transcript Map of a Tumor-Suppressing Subchromosomal Transferable Fragment from 11p15.5, and Isolation and Sequence Analysis of Three Novel Genes ⬇️

scientific article published on November 15, 1997

A comparison of non-integrating reprogramming methods

scientific article

A genetic approach to cancer epigenetics

scientific article published on 01 January 2005

A novel general strategy for cloning tumor suppressor genes using radiation-reduced chromosomal superfragments

scientific article published on 01 October 1992

A nucleolar protein, H19 opposite tumor suppressor (HOTS), is a tumor growth inhibitor encoded by a human imprinted H19 antisense transcript.

scientific article

A selective phenelzine analogue inhibitor of histone demethylase LSD1.

scientific article published on 7 April 2014

A species-generalized probabilistic model-based definition of CpG islands

scientific article published on 24 September 2009

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity ⬇️

scientific article published on July 1, 1983

A third-generation method reveals cell lineage ancestry.

scientific article published on February 2013

Accurate genome-scale percentage DNA methylation estimates from microarray data

scientific article

Adaptation of the CHARM DNA methylation platform for the rat genome reveals novel brain region-specific differences ⬇️

scientific article published on November 1, 2011

Addition of H19 'loss of methylation testing' for Beckwith-Wiedemann syndrome (BWS) increases the diagnostic yield.

scientific article

Age and sun exposure-related widespread genomic blocks of hypomethylation in nonmalignant skin

scientific article published on 16 April 2015

An LSC epigenetic signature is largely mutation independent and implicates the HOXA cluster in AML pathogenesis

scientific article

An integrated epigenetic and genetic approach to common human disease

scientific article published on 01 August 2004

Association between Beckwith-Wiedemann syndrome and assisted reproductive technology: a case series of 19 patients.

scientific article

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

scientific article

Association of chromosome arm 16q loss with loss of imprinting of insulin-like growth factor-II in Wilms tumor.

scientific article

Association of in vitro fertilization with Beckwith-Wiedemann syndrome and epigenetic alterations of LIT1 and H19

scientific article

Author Correction: Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship.

scientific article published on 7 March 2018

BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression

scientific article

BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma

scientific article

Bump hunting to identify differentially methylated regions in epigenetic epidemiology studies.

scientific article published in February 2012

Butyrophenone influences on the opiate receptor

scientific article published in March 1976

Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host

scientific article

Cancer epigenetics is no Mickey Mouse

scientific article published on 01 October 2005

Cancer epigenetics takes center stage.

scientific article published in January 2001

Children with idiopathic hemihypertrophy and beckwith-wiedemann syndrome have different constitutional epigenotypes associated with wilms tumor

scientific article

Cloning of candidate genes involved in the Beckwith-Wiedemann syndrome and childhood tumors

scientific article published on 01 November 1996

Common DNA methylation alterations in multiple brain regions in autism.

scientific article

Comprehensive high-throughput arrays for relative methylation (CHARM)

scientific article published on 01 April 2010

Comprehensive high-throughput arrays for relative methylation (CHARM).

scientific article

Comprehensive methylome map of lineage commitment from haematopoietic progenitors

scientific article

Converging genetic and epigenetic drivers of paediatric acute lymphoblastic leukaemia identified by an information-theoretic analysis

scientific article published on 15 April 2021

Cross-tissue integration of genetic and epigenetic data offers insight into autism spectrum disorder

scientific article published on 24 October 2017

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis

scientific article published on 30 March 2016

DNA methylation age of blood predicts all-cause mortality in later life

scientific article

DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis.

scientific article

DNA methylation in cancer: three decades of discovery.

scientific article

DNA methylation is stable during replication and cell cycle arrest

scientific article

DNA methylation mediates genotype and smoking interaction in the development of anti-citrullinated peptide antibody-positive rheumatoid arthritis

scientific article published on 29 March 2017

DNA methylation shows genome-wide association of NFIX, RAPGEF2 and MSRB3 with gestational age at birth

scientific article

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

scientific article published on 12 December 2016

DNA methylation-based measures of biological age: meta-analysis predicting time to death

scientific article

DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation

scientific article

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

scientific article (publication date: 4 April 2002)

Detailed DNA methylation profiles of the E-cadherin promoter in the NCI-60 cancer cells.

scientific article

Detection of haplotype-dependent allele-specific DNA methylation in WGBS data

scientific article published on 16 October 2020

Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

scientific article

Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach.

scientific article

Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells

scientific article

Epigenetic alterations of H19 and LIT1 distinguish patients with Beckwith-Wiedemann syndrome with cancer and birth defects

scientific article

Epigenetic effects in eukaryotic gene expression.

scientific article published on January 1994

Epigenetic memory in induced pluripotent stem cells

scientific article (publication date: 16 September 2010)

Epigenetic modulators, modifiers and mediators in cancer aetiology and progression

scientific article

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

scientific article

Epigenetic specificity of loss of imprinting of the IGF2 gene in Wilms tumors.

scientific article published on 8 August 2007

Epigenetic stochasticity, nuclear structure and cancer: the implications for medicine.

scientific article

Epigenetic variability and the evolution of human cancer.

scientific article

Epigenetics at the Crossroads of Genes and the Environment.

scientific article published in September 2015

Epigenetics at the epicenter of modern medicine

scientific article published on 01 March 2008

Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis

scientific article

Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis

scientific article published on 16 January 2017

Epigenomics reveals a functional genome anatomy and a new approach to common disease ⬇️

scientific article published on October 1, 2010

Euchromatin islands in large heterochromatin domains are enriched for CTCF binding and differentially DNA-methylated regions

scientific article

Factors associated with preterm delivery in mothers of children with Beckwith-Wiedemann syndrome: a case cohort study from the BWS registry.

scientific article

GeMes, clusters of DNA methylation under genetic control, can inform genetic and epigenetic analysis of disease

scientific article published on 20 March 2014

Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: association with HMG2L1 and TOM1.

scientific article

Genetics and epigenetics--nature's pen-and-pencil set

scientific article published on 01 February 2007

Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition

scientific article published on 3 July 2011

Genomic imprinting and gene activation in cancer

scientific article published on 01 June 1993

Genomic imprinting, DNA methylation, and cancer.

scientific article published on May 1994

High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis

scientific article

Higher order chromatin organization in cancer ⬇️

scientific article published on December 22, 2012

Hot-stop PCR: a simple and general assay for linear quantitation of allele ratios

scientific article published on 01 August 2000

Human KVLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements

scientific article published in February 1997

Human brain region-specific variably methylated regions are enriched for heritability of distinct neuropsychiatric traits

scientific article published on 22 April 2021

Hypomethylation distinguishes genes of some human cancers from their normal counterparts ⬇️

scientific article (publication date: 6 January 1983)

Hypomethylation of ras oncogenes in primary human cancers

scientific article published on 01 February 1983

Identification and Mapping of Human Histone Acetylation Modifier Gene Homologues ⬇️

scientific article published on July 15, 1998

Increase in Science Research Commitment in a Didactic and Laboratory-Based Program Targeted to Gifted Minority High-School Students.

scientific article published on 10 January 2013

Increased methylation variation in epigenetic domains across cancer types

scientific article published on 26 June 2011

Inheritance pattern of Beckwith-Wiedemann syndrome is heterogeneous in 291 families with an affected proband.

scientific article published in August 2005

Interview: Professor Andrew Feinberg Speaks To Epigenomics ⬇️

scientific article published on October 1, 2009

Intra-individual change over time in DNA methylation with familial clustering

scientific article

Lack of parental origin specificity of altered alleles at 11p15 in testicular germ cell tumors

scientific article published in November 2003

Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells

scientific article published on 18 January 2009

Large hypomethylated blocks as a universal defining epigenetic alteration in human solid tumors

scientific article

Large-scale hypomethylated blocks associated with Epstein-Barr virus-induced B-cell immortalization

scientific article published on 25 September 2013

Limited up-regulation of DNA methyltransferase in human colon cancer reflecting increased cell proliferation.

scientific article published on September 1996

Loss of IGF2 imprinting: a potential marker of colorectal cancer risk

scientific article published on 01 March 2003

Loss of genes on the short arm of chromosome 11 in bladder cancer

scientific article published in Nature

Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability

scientific article published on 01 November 1998

Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour

scientific article published on 01 July 1994

Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice

scientific article published on 24 February 2005

Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition.

scientific article published in April 2004

Low Frequency of p57KIP2 Mutation in Beckwith-Wiedemann Syndrome ⬇️

scientific article published on August 1, 1997

Mendel stayed home. Genomic imprinting and environmental disease susceptibility, National Institute of Environmental Health Sciences and Duke University Medical Center, Durham, NC, USA, 8-10 October 1998

scientific article published on 01 February 1999

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

article

Methylation meets genomics

scientific article published on 01 January 2001

Microallelotyping defines the sequence and tempo of allelic losses at tumour suppressor gene loci during colorectal cancer progression

scientific article

Microdeletion of LIT1 in familial Beckwith-Wiedemann syndrome

scientific article

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

scientific article

Mouse-human experimental epigenetic analysis unmasks dietary targets and genetic liability for diabetic phenotypes

scientific article published in January 2015

Multiple genetic loci within 11p15 defined by Beckwith-Wiedemann syndrome rearrangement breakpoints and subchromosomal transferable fragments

scientific article

Multiple tumor suppressor genes in multistep carcinogenesis.

scientific article published in October 1992

Mutant WT1 is associated with DNA hypermethylation of PRC2 targets in AML and responds to EZH2 inhibition

scientific article

Nanoelectromechanics of methylated DNA in a synthetic nanopore.

scientific article published on February 2009

Neuronal brain-region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability

scientific article published on 14 January 2019

Overlapping euchromatin/heterochromatin- associated marks are enriched in imprinted gene regions and predict allele-specific modification

scientific article published on 10 October 2008

Parent-of-origin effects in autism identified through genome-wide linkage analysis of 16,000 SNPs

scientific article

Paternal sperm DNA methylation associated with early signs of autism risk in an autism-enriched cohort

scientific article

Personalized epigenomic signatures that are stable over time and covary with body mass index

scientific article

Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation.

scientific article

Potential energy landscapes identify the information-theoretic nature of the epigenome

scientific article published on 27 March 2017

Prenatal mercury concentration is associated with changes in DNA methylation at TCEANC2 in newborns

scientific article

Redefining CpG islands using hidden Markov models

scientific article

Regulated Noise in the Epigenetic Landscape of Development and Disease ⬇️

scientific article published on March 16, 2012

Reversible switching between epigenetic states in honeybee behavioral subcastes

scientific article

SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria

scientific article

SNP-specific array-based allele-specific expression analysis

scientific article

Significance analysis and statistical dissection of variably methylated regions

scientific article published on 17 June 2011

Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship

scientific article published on 6 November 2017

Somatic deletion and duplication of genes on chromosome 11 in Wilms' tumours

scientific article published in May 1984

Stem cell differentiation as a renewal-reward process: predictions and validation in the colonic crypt

scientific article published in January 2012

Strain-dependent developmental relaxation of imprinting of an endogenous mouse gene, Kvlqt1.

scientific article published in November 1998

Syntenic organization of the mouse distal chromosome 7 imprinting cluster and the Beckwith-Wiedemann syndrome region in chromosome 11p15.5.

scientific article published in July 1998

TaqI and RsaI polymorphisms in the H19 gene (D11S813E)

scientific article published on 01 June 1993

Targeted regulation of imprinted genes by synthetic zinc-finger transcription factors.

scientific article published in March 2003

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight

scientific article

The commonality of plasticity underlying multipotent tumor cells and embryonic stem cells.

scientific article published on July 2007

The epigenetic progenitor origin of human cancer

scientific article (publication date: 2006)

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

scientific article

The new field of epigenomics: implications for cancer and other common disease research.

scientific article

The nucleolus gets the silent treatment

scientific article published on December 2014

Transcribed dinucleotide repeat polymorphism in the IGF2 gene

scientific article published on 01 February 1994

Whole-genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver

scientific article published on 13 October 2016

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