List of works - Akhteruzzaman Molla

2-Pyridyl P1'-substituted symmetry-based human immunodeficiency virus protease inhibitors (A-792611 and A-790742) with potential for convenient dosing and reduced side effects

scientific article

A replicon-based shuttle vector system for assessing the phenotype of HCV NS5B polymerase genes isolated from patient populations

scientific article published on 29 June 2007

Activity of a Potent Hepatitis C Virus Polymerase Inhibitor in the Chimpanzee Model

scientific article

Antiviral interactions of an HCV polymerase inhibitor with an HCV protease inhibitor or interferon in vitro

scientific article published on 17 August 2006

Aryl uracil inhibitors of hepatitis C virus NS5B polymerase: synthesis and characterization of analogs with a fused 5,6-bicyclic ring motif

scientific article published in May 2013

Characterization of a novel human immunodeficiency virus type 1 protease inhibitor, A-790742.

scientific article published on 22 January 2008

Characterization of resistant HIV variants generated by in vitro passage with lopinavir/ritonavir

scientific article published in August 2003

Complementation in cells cotransfected with a mixture of wild-type and mutant human immunodeficiency virus (HIV) influences the replication capacities and phenotypes of mutant variants in a single-cycle HIV resistance assay

scientific article

Conserved residues in the coiled-coil pocket of human immunodeficiency virus type 1 gp41 are essential for viral replication and interhelical interaction

scientific article

Development of a cell-based assay for high-throughput screening of inhibitors against HCV genotypes 1a and 1b in a single well

scientific article published on 25 January 2009

Discovery of pyrido[2,3-d]pyrimidine-based inhibitors of HCV NS5A.

scientific article published on 10 April 2013

Evolution of Resistant M414T Mutants among Hepatitis C Virus Replicon Cells Treated with Polymerase Inhibitor A-782759

scientific article

Evolving therapeutic paradigms for HIV and HCV.

scientific article published on December 2003

Hepatitis C NS3 protease inhibition by peptidyl-alpha-ketoamide inhibitors: kinetic mechanism and structure

scientific article published on January 2004

Hepatitis C NS5B polymerase inhibitors: 4,4-Dialkyl-1-hydroxy-3-oxo-3,4-dihydronaphthalene-3-yl benzothiadiazine derivatives

scientific article published on 18 June 2008

Hepatitis C NS5B polymerase inhibitors: Functional equivalents for the benzothiadiazine moiety ⬇️

scientific article published on January 13, 2011

Identification and structural characterization of I84C and I84A mutations that are associated with high-level resistance to human immunodeficiency virus protease inhibitors and impair viral replication

scientific article published on 13 November 2006

Identification of aryl dihydrouracil derivatives as palm initiation site inhibitors of HCV NS5B polymerase ⬇️

scientific article published on April 10, 2012

Identification of halosalicylamide derivatives as a novel class of allosteric inhibitors of HCV NS5B polymerase

scientific article published on May 2008

Identification of host genes involved in hepatitis C virus replication by small interfering RNA technology

scientific article

In vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitor

scientific article published on 22 December 2014

In vitro and in vivo antiviral activity and resistance profile of ombitasvir, an inhibitor of hepatitis C virus NS5A.

scientific article

In vitro and in vivo antiviral activity and resistance profile of the hepatitis C virus NS3/4A protease inhibitor ABT-450.

scientific article published on December 2014

In vitro antiviral interaction of lopinavir with other protease inhibitors

scientific article published on July 2002

In vitro characterization of A-315675, a highly potent inhibitor of A and B strain influenza virus neuraminidases and influenza virus replication

scientific article

In vitro selection and characterization of human immunodeficiency virus type 2 with decreased susceptibility to lopinavir

scientific article

In vitro selection and characterization of influenza A (A/N9) virus variants resistant to a novel neuraminidase inhibitor, A-315675.

scientific article

Inhibition of human immunodeficiency virus type I integrase by naphthamidines and 2-aminobenzimidazoles

scientific article published on October 2004

Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-1-heteroalkyl-4-hydroxyquinolon-3-yl-benzothiadiazines

scientific article published on March 2005

Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of unsymmetrical 1-hydroxy-4,4-dialkyl-3-oxo-3,4-dihydronaphthalene benzothiadiazine derivatives

scientific article published on 27 January 2007

Inhibitors of hepatitis C virus polymerase: synthesis and biological characterization of unsymmetrical dialkyl-hydroxynaphthalenoyl-benzothiadiazines

scientific article published on March 2009

Investigating the origin of the slow-binding inhibition of HCV NS3 serine protease by a novel substrate based inhibitor

scientific article published in July 2003

Mutations conferring resistance to a hepatitis C virus (HCV) RNA-dependent RNA polymerase inhibitor alone or in combination with an HCV serine protease inhibitor in vitro

scientific article

Mutations conferring resistance to a potent hepatitis C virus serine protease inhibitor in vitro

scientific article

Novel Hepatitis C virus replicon inhibitors: Synthesis and structure–activity relationships of fused pyrimidine derivatives ⬇️

scientific article published on February 2, 2012

P1-substituted symmetry-based human immunodeficiency virus protease inhibitors with potent antiviral activity against drug-resistant viruses

scientific article published on September 21, 2011

Relative Replication Capacity and Selective Advantage Profiles of Protease Inhibitor-Resistant Hepatitis C Virus (HCV) NS3 Protease Mutants in the HCV Genotype 1b Replicon System

scientific article

Replication efficiency of chimeric replicon containing NS5A-5B genes derived from HCV-infected patient sera

scientific article published on 28 July 2006

Selection of resistance in protease inhibitor-experienced, human immunodeficiency virus type 1-infected subjects failing lopinavir- and ritonavir-based therapy: mutation patterns and baseline correlates

scientific article published on March 2005

Small-sized human immunodeficiency virus type-1 protease inhibitors containing allophenylnorstatine to explore the S2' pocket

scientific article

Structure-based characterization and optimization of novel hydrophobic binding interactions in a series of pyrrolidine influenza neuraminidase inhibitors

scientific article published in June 2005

Synthesis and biological characterization of B-ring amino analogues of potent benzothiadiazine hepatitis C virus polymerase inhibitors

scientific article published on May 2009

Synthesis of potent pyrrolidine influenza neuraminidase inhibitors

scientific article

Synthesis, antiviral activity, and pharmacokinetic evaluation of P3 pyridylmethyl analogs of oximinoarylsulfonyl HIV-1 protease inhibitors

scientific article published on 28 February 2006

Water-soluble prodrugs of the human immunodeficiency virus protease inhibitors lopinavir and ritonavir

scientific article published in May 2009

List of works by Akhteruzzaman Molla

2-Pyridyl P1'-substituted symmetry-based human immunodeficiency virus protease inhibitors (A-792611 and A-790742) with potential for convenient dosing and reduced side effects

A replicon-based shuttle vector system for assessing the phenotype of HCV NS5B polymerase genes isolated from patient populations

Activity of a Potent Hepatitis C Virus Polymerase Inhibitor in the Chimpanzee Model

Antiviral interactions of an HCV polymerase inhibitor with an HCV protease inhibitor or interferon in vitro

Aryl uracil inhibitors of hepatitis C virus NS5B polymerase: synthesis and characterization of analogs with a fused 5,6-bicyclic ring motif

Characterization of a novel human immunodeficiency virus type 1 protease inhibitor, A-790742.

Characterization of resistant HIV variants generated by in vitro passage with lopinavir/ritonavir

Complementation in cells cotransfected with a mixture of wild-type and mutant human immunodeficiency virus (HIV) influences the replication capacities and phenotypes of mutant variants in a single-cycle HIV resistance assay

Conserved residues in the coiled-coil pocket of human immunodeficiency virus type 1 gp41 are essential for viral replication and interhelical interaction

Development of a cell-based assay for high-throughput screening of inhibitors against HCV genotypes 1a and 1b in a single well

Discovery of pyrido[2,3-d]pyrimidine-based inhibitors of HCV NS5A.

Evolution of Resistant M414T Mutants among Hepatitis C Virus Replicon Cells Treated with Polymerase Inhibitor A-782759

Evolving therapeutic paradigms for HIV and HCV.

Hepatitis C NS3 protease inhibition by peptidyl-alpha-ketoamide inhibitors: kinetic mechanism and structure

Hepatitis C NS5B polymerase inhibitors: 4,4-Dialkyl-1-hydroxy-3-oxo-3,4-dihydronaphthalene-3-yl benzothiadiazine derivatives

Hepatitis C NS5B polymerase inhibitors: Functional equivalents for the benzothiadiazine moiety ⬇️

Identification and structural characterization of I84C and I84A mutations that are associated with high-level resistance to human immunodeficiency virus protease inhibitors and impair viral replication

Identification of aryl dihydrouracil derivatives as palm initiation site inhibitors of HCV NS5B polymerase ⬇️

Identification of halosalicylamide derivatives as a novel class of allosteric inhibitors of HCV NS5B polymerase

Identification of host genes involved in hepatitis C virus replication by small interfering RNA technology

In vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitor

In vitro and in vivo antiviral activity and resistance profile of ombitasvir, an inhibitor of hepatitis C virus NS5A.

In vitro and in vivo antiviral activity and resistance profile of the hepatitis C virus NS3/4A protease inhibitor ABT-450.

In vitro antiviral interaction of lopinavir with other protease inhibitors

In vitro characterization of A-315675, a highly potent inhibitor of A and B strain influenza virus neuraminidases and influenza virus replication

In vitro selection and characterization of human immunodeficiency virus type 2 with decreased susceptibility to lopinavir

In vitro selection and characterization of influenza A (A/N9) virus variants resistant to a novel neuraminidase inhibitor, A-315675.

Inhibition of human immunodeficiency virus type I integrase by naphthamidines and 2-aminobenzimidazoles

Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-1-heteroalkyl-4-hydroxyquinolon-3-yl-benzothiadiazines

Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of unsymmetrical 1-hydroxy-4,4-dialkyl-3-oxo-3,4-dihydronaphthalene benzothiadiazine derivatives

Inhibitors of hepatitis C virus polymerase: synthesis and biological characterization of unsymmetrical dialkyl-hydroxynaphthalenoyl-benzothiadiazines

Investigating the origin of the slow-binding inhibition of HCV NS3 serine protease by a novel substrate based inhibitor

Mutations conferring resistance to a hepatitis C virus (HCV) RNA-dependent RNA polymerase inhibitor alone or in combination with an HCV serine protease inhibitor in vitro

Mutations conferring resistance to a potent hepatitis C virus serine protease inhibitor in vitro

Novel Hepatitis C virus replicon inhibitors: Synthesis and structure–activity relationships of fused pyrimidine derivatives ⬇️

P1-substituted symmetry-based human immunodeficiency virus protease inhibitors with potent antiviral activity against drug-resistant viruses

Relative Replication Capacity and Selective Advantage Profiles of Protease Inhibitor-Resistant Hepatitis C Virus (HCV) NS3 Protease Mutants in the HCV Genotype 1b Replicon System

Replication efficiency of chimeric replicon containing NS5A-5B genes derived from HCV-infected patient sera

Selection of resistance in protease inhibitor-experienced, human immunodeficiency virus type 1-infected subjects failing lopinavir- and ritonavir-based therapy: mutation patterns and baseline correlates

Small-sized human immunodeficiency virus type-1 protease inhibitors containing allophenylnorstatine to explore the S2' pocket

Structure-based characterization and optimization of novel hydrophobic binding interactions in a series of pyrrolidine influenza neuraminidase inhibitors

Synthesis and biological characterization of B-ring amino analogues of potent benzothiadiazine hepatitis C virus polymerase inhibitors

Synthesis of potent pyrrolidine influenza neuraminidase inhibitors

Synthesis, antiviral activity, and pharmacokinetic evaluation of P3 pyridylmethyl analogs of oximinoarylsulfonyl HIV-1 protease inhibitors

Water-soluble prodrugs of the human immunodeficiency virus protease inhibitors lopinavir and ritonavir