List of works - Tatyana Dekhtyar

2-Pyridyl P1'-substituted symmetry-based human immunodeficiency virus protease inhibitors (A-792611 and A-790742) with potential for convenient dosing and reduced side effects

scientific article

A replicon-based shuttle vector system for assessing the phenotype of HCV NS5B polymerase genes isolated from patient populations

scientific article published on 29 June 2007

Antiviral interactions of an HCV polymerase inhibitor with an HCV protease inhibitor or interferon in vitro

scientific article published on 17 August 2006

Characterization of a novel human immunodeficiency virus type 1 protease inhibitor, A-790742.

scientific article published on 22 January 2008

Characterization of resistant HIV variants generated by in vitro passage with lopinavir/ritonavir

scientific article published in August 2003

Conserved residues in the coiled-coil pocket of human immunodeficiency virus type 1 gp41 are essential for viral replication and interhelical interaction

scientific article

Design and synthesis of pseudo-symmetric HIV protease inhibitors containing a novel hydroxymethylcarbonyl (HMC)-hydrazide isostere

scientific article published in January 2003

Discovery of fluorobenzimidazole HCV NS5A inhibitors

scientific article published on 13 October 2016

Hepatitis C virus genotype 4 resistance and subtype demographic characterization of patients treated with ombitasvir plus paritaprevir/ritonavir

scientific article

Identification and characterization of mutations conferring resistance to an HCV RNA-dependent RNA polymerase inhibitor in vitro

scientific article

Identification and structural characterization of I84C and I84A mutations that are associated with high-level resistance to human immunodeficiency virus protease inhibitors and impair viral replication

scientific article published on 13 November 2006

In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS3/4A Protease Inhibitor Glecaprevir

scientific article published on 30 October 2017

In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS5A Inhibitor Pibrentasvir

scientific article published on 13 February 2017

In vitro and in vivo antiviral activity and resistance profile of the hepatitis C virus NS3/4A protease inhibitor ABT-450.

scientific article published on December 2014

In vitro selection and characterization of human immunodeficiency virus type 2 with decreased susceptibility to lopinavir

scientific article

Mutations conferring resistance to a hepatitis C virus (HCV) RNA-dependent RNA polymerase inhibitor alone or in combination with an HCV serine protease inhibitor in vitro

scientific article

Oximinoarylsulfonamides as potent HIV protease inhibitors

scientific article

P1-substituted symmetry-based human immunodeficiency virus protease inhibitors with potent antiviral activity against drug-resistant viruses

scientific article published on September 21, 2011

Synthesis and antiviral activity of P1' arylsulfonamide azacyclic urea HIV protease inhibitors

scientific article

Synthesis, antiviral activity, and pharmacokinetic evaluation of P3 pyridylmethyl analogs of oximinoarylsulfonyl HIV-1 protease inhibitors

scientific article published on 28 February 2006

List of works by Tatyana Dekhtyar

2-Pyridyl P1'-substituted symmetry-based human immunodeficiency virus protease inhibitors (A-792611 and A-790742) with potential for convenient dosing and reduced side effects

A replicon-based shuttle vector system for assessing the phenotype of HCV NS5B polymerase genes isolated from patient populations

Antiviral interactions of an HCV polymerase inhibitor with an HCV protease inhibitor or interferon in vitro

Characterization of a novel human immunodeficiency virus type 1 protease inhibitor, A-790742.

Characterization of resistant HIV variants generated by in vitro passage with lopinavir/ritonavir

Conserved residues in the coiled-coil pocket of human immunodeficiency virus type 1 gp41 are essential for viral replication and interhelical interaction

Design and synthesis of pseudo-symmetric HIV protease inhibitors containing a novel hydroxymethylcarbonyl (HMC)-hydrazide isostere

Discovery of fluorobenzimidazole HCV NS5A inhibitors

Hepatitis C virus genotype 4 resistance and subtype demographic characterization of patients treated with ombitasvir plus paritaprevir/ritonavir

Identification and characterization of mutations conferring resistance to an HCV RNA-dependent RNA polymerase inhibitor in vitro

Identification and structural characterization of I84C and I84A mutations that are associated with high-level resistance to human immunodeficiency virus protease inhibitors and impair viral replication

In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS3/4A Protease Inhibitor Glecaprevir

In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS5A Inhibitor Pibrentasvir

In vitro and in vivo antiviral activity and resistance profile of the hepatitis C virus NS3/4A protease inhibitor ABT-450.

In vitro selection and characterization of human immunodeficiency virus type 2 with decreased susceptibility to lopinavir

Mutations conferring resistance to a hepatitis C virus (HCV) RNA-dependent RNA polymerase inhibitor alone or in combination with an HCV serine protease inhibitor in vitro

Oximinoarylsulfonamides as potent HIV protease inhibitors

P1-substituted symmetry-based human immunodeficiency virus protease inhibitors with potent antiviral activity against drug-resistant viruses

Synthesis and antiviral activity of P1' arylsulfonamide azacyclic urea HIV protease inhibitors

Synthesis, antiviral activity, and pharmacokinetic evaluation of P3 pyridylmethyl analogs of oximinoarylsulfonyl HIV-1 protease inhibitors