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List of works by Mikihito Kajiya

A novel gingival overgrowth mouse model induced by the combination of CsA and ligature-induced inflammation

scientific article published on 5 March 2017

A novel method of sampling gingival crevicular fluid from a mouse model of periodontitis.

scientific article

A role of oral bacteria in bisphosphonate-induced osteonecrosis of the jaw.

scientific article

Additive effects of orexin B and vasoactive intestinal polypeptide on LL-37-mediated antimicrobial activities.

scientific article

Aggregatibacter actinomycetemcomitans Omp29 is associated with bacterial entry to gingival epithelial cells by F-actin rearrangement.

scientific article

Aggregatibacter actinomycetemcomitans outer membrane protein 29 (Omp29) induces TGF-β-regulated apoptosis signal in human gingival epithelial cells via fibronectin/integrinβ1/FAK cascade

scientific article published on 28 April 2016

Aggressive periodontitis and NOD2 variants

scientific article published on 19 May 2020

Amphotericin B down-regulates Aggregatibacter actinomycetemcomitans-induced production of IL-8 and IL-6 in human gingival epithelial cells

scientific article published on 11 July 2014

Antimicrobial peptide LL37 promotes vascular endothelial growth factor‐A expression in human periodontal ligament cells

scientific article published on September 3, 2012

Azithromycin recovers reductions in barrier function in human gingival epithelial cells stimulated with tumor necrosis factor-α.

scientific article published on 24 November 2015

BDNF mimetic compound LM22A-4 regulates cementoblast differentiation via the TrkB-ERK/Akt signaling cascade.

scientific article published on 11 February 2014

BDNF/HMW-HA complex as an adjunct to nonsurgical periodontal treatment of ligature-induced periodontitis in dogs

scientific article published on 30 August 2018

Bacteria-derived hydrogen sulfide promotes IL-8 production from epithelial cells.

scientific article

Brain-Derived Neurotrophic Factor Inhibits Intercellular Adhesion Molecule-1 Expression in Interleukin-1β-Treated Endothelial Cells.

scientific article published on 17 June 2016

Brain-Derived Neurotrophic Factor Inhibits Peptidoglycan-Induced Inflammatory Cytokine Expression in Human Dental Pulp Cells

scientific article published on 16 November 2016

Brain-derived neurotrophic factor induces migration of endothelial cells through a TrkB-ERK-integrin αVβ3-FAK cascade

scientific article published in May 2012

Brain-derived neurotrophic factor prevents the endothelial barrier dysfunction induced by interleukin-1β and tumor necrosis factor-α.

scientific article published on 9 September 2014

Brain-derived neurotrophic factor protects cementoblasts from serum starvation-induced cell death.

scientific article

Brain-derived neurotrophic factor stimulates bone/cementum-related protein gene expression in cementoblasts.

scientific article

Characteristics of high-molecular-weight hyaluronic acid as a brain-derived neurotrophic factor scaffold in periodontal tissue regeneration

scientific article published on 16 January 2011

Clumps of Mesenchymal Stem Cell/Extracellular Matrix Complexes Generated with Xeno-Free Conditions Facilitate Bone Regeneration via Direct and Indirect Osteogenesis

scientific article published on 15 August 2019

Clumps of a mesenchymal stromal cell/extracellular matrix complex can be a novel tissue engineering therapy for bone regeneration

scientific article published on 3 March 2015

Corrigendum to "A novel method of sampling gingival crevicular fluid from a mouse model of periodontitis" [J Immunol Methods 438 (2016) 21-25].

scientific article

Cryopreserved clumps of mesenchymal stem cell/extracellular matrix complexes retain osteogenic capacity and induce bone regeneration

scientific article published on 21 March 2018

DC-STAMP Is an Osteoclast Fusogen Engaged in Periodontal Bone Resorption.

scientific article published on February 2017

Detection of periodontal pathogens in newborns and children with mixed dentition

scientific article published on September 18, 2011

Distinction Between Cell Proliferation and Apoptosis Signals Regulated by Brain-Derived Neurotrophic Factor in Human Periodontal Ligament Cells and Gingival Epithelial Cells

scientific article published on 18 November 2015

Effect of local bone marrow stromal cell administration on ligature-induced periodontitis in mice

scientific article published in January 2017

Effect of neurotrophins on differentiation, calcification and proliferation in cultures of human pulp cells.

scientific article published on 17 July 2007

Expression levels of novel cytokine IL-32 in periodontitis and its role in the suppression of IL-8 production by human gingival fibroblasts stimulated withPorphyromonas gingivalis

scientific article published on March 16, 2012

Fluoxetine inhibits inflammatory response and bone loss in a rat model of ligature-induced periodontitis.

scientific article

GlmS and NagB regulate amino sugar metabolism in opposing directions and affect Streptococcus mutans virulence

scientific journal article

Glycyrrhizic acid suppresses inflammation and reduces the increased glucose levels induced by the combination of Porphyromonas gulae and ligature placement in diabetic model mice

scientific article published on 30 December 2018

Humoral factors released from human periodontal ligament cells influence calcification and proliferation in human bone marrow mesenchymal stem cells

Hydrogen from intestinal bacteria is protective for Concanavalin A-induced hepatitis.

scientific article

Hydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate

scientific article

IL-6 Induced by Periodontal Inflammation Causes Neuroinflammation and Disrupts the Blood-Brain Barrier

scientific article published on 27 September 2020

Inhibition of matrix metalloproteinase-9 activity by doxycycline ameliorates RANK ligand-induced osteoclast differentiation in vitro and in vivo.

scientific article published on 21 March 2011

Interleukin-8 induces DNA synthesis, migration and down-regulation of cleaved caspase-3 in cultured human gingival epithelial cells

scientific article published on 20 September 2014

Intravital endoscopic technology for real-time monitoring of inflammation caused in experimental periodontitis

scientific article published on 19 March 2018

Involvement of smad2 and Erk/Akt cascade in TGF-β1-induced apoptosis in human gingival epithelial cells.

scientific article

Irsogladine maleate counters the interleukin-1 beta-induced suppression in gap-junctional intercellular communication but does not affect the interleukin-1 beta-induced zonula occludens protein-1 levels in human gingival epithelial cells.

scientific article published in February 2008

Irsogladine maleate inhibits Porphyromonas gingivalis-mediated expression of toll-like receptor 2 and interleukin-8 in human gingival epithelial cells.

scientific article published on 20 September 2014

Irsogladine maleate regulates neutrophil migration and E-cadherin expression in gingival epithelium stimulated by Aggregatibacter actinomycetemcomitans.

scientific article published on 22 January 2010

Irsogladine maleate regulates the inflammatory related genes in human gingival epithelial cells stimulated by Aggregatibacter actinomycetemcomitans.

scientific article published on 8 January 2013

LL37 induces VEGF expression in dental pulp cells through ERK signalling

scientific article published on 12 September 2014

MSC/ECM Cellular Complexes Induce Periodontal Tissue Regeneration

scientific article published in May 2017

Mobilization of TLR4 Into Lipid Rafts by Aggregatibacter Actinomycetemcomitans in Gingival Epithelial Cells

scientific article published on 17 October 2016

Muscarinic type 3 receptor induces cytoprotective signaling in salivary gland cells through epidermal growth factor receptor transactivation

scientific article

Neodymium-doped yttrium-aluminium-garnet laser irradiation abolishes the increase in interleukin-6 levels caused by peptidoglycan through the p38 mitogen-activated protein kinase pathway in human pulp cells

scientific article

Nuclear Nrf2 induction by protein transduction attenuates osteoclastogenesis

scientific article published on 16 September 2014

Porphyromonas gingivalis infection exacerbates the onset of rheumatoid arthritis in SKG mice.

scientific article published on 27 July 2016

Regulation of defensive function on gingival epithelial cells can prevent periodontal disease

scientific article

Reparative bone-like tissue formation in the tooth of a systemic sclerosis patient

scientific article published on 14 March 2018

Role of periodontal pathogenic bacteria in RANKL-mediated bone destruction in periodontal disease

scientific article published on November 8, 2010

Selective serotonin reuptake inhibitors attenuate the antigen presentation from dendritic cells to effector T lymphocytes.

scientific article

Sequential process in brain-derived neurotrophic factor-induced functional periodontal tissue regeneration

scientific article published on 12 February 2016

Smad2 is involved in Aggregatibacter actinomycetemcomitans-induced apoptosis

scientific article

The Keap1/Nrf2 protein axis plays a role in osteoclast differentiation by regulating intracellular reactive oxygen species signaling

scientific article published on 25 June 2013

The antimicrobial activity of the appetite peptide hormone ghrelin

scientific article

The antimicrobial peptide LL37 promotes bone regeneration in a rat calvarial bone defect.

scientific article

The differential expression of mgl mRNA by Porphyromonas gingivalis affects the production of methyl mercaptan

scientific article published on 24 April 2015

The induced RNA-binding protein, HuR targets 3'-UTR region of IL-6 mRNA and enhances its stabilization in periodontitis

scientific article

The involvement of C5a in the progression of experimental arthritis with Porphyromonas gingivalis infection in SKG mice

scientific article published on 03 November 2018

Type I collagen deposition via osteoinduction ameliorates YAP/TAZ activity in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes

article

Xenotransplantation of interferon-gamma-pretreated clumps of a human mesenchymal stem cell/extracellular matrix complex induces mouse calvarial bone regeneration

scientific article

miR-584 expressed in human gingival epithelial cells is induced by Porphyromonas gingivalis stimulation and regulates interleukin-8 production via lactoferrin receptor

scientific article published on 14 November 2013