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List of works by Michael G Schlossmacher

A First Tetraplex Assay for the Simultaneous Quantification of Total α-Synuclein, Tau, β-Amyloid42 and DJ-1 in Human Cerebrospinal Fluid

scientific article

Acid β-glucosidase mutants linked to Gaucher disease, Parkinson disease, and Lewy body dementia alter α-synuclein processing.

scientific article published on 6 April 2011

Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites

scientific article published on 10 March 2021

Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo.

scientific article published in March 2007

Alpha-synuclein in the appendiceal mucosa of neurologically intact subjects.

scientific article

Association of SNCA with Parkinson: Replication in the Harvard NeuroDiscovery Center Biomarker Study ⬇️

scientific article published on September 23, 2011

Aβ oligomers induce pathophysiological mGluR5 signaling in Alzheimer's disease model mice in a sex-selective manner

scientific article published on 15 December 2020

Biological confounders for the values of cerebrospinal fluid proteins in Parkinson's disease and related disorders

scientific article published on 10 October 2015

Biomarker research in Parkinson's disease: objective measures needed for patient stratification in future cause-directed trials

scientific article published in October 2010

CNS expression of glucocerebrosidase corrects alpha-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy

scientific article

CSF synuclein: adding to the biomarker footprint of dementia with Lewy bodies

scientific article

Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 27-2004. A 79-year-old woman with disturbances in gait, cognition, and autonomic function

scientific article published on 01 August 2004

Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo.

scientific article published on 09 February 2009

Considerations regarding the etiology and future treatment of autosomal recessive versus idiopathic Parkinson disease.

scientific article published on June 2012

Conversations With Dr. Oleh Hornykiewicz, Founding Father of the Dopamine Era in Parkinson's: How Do You Wish to Be Remembered?

scientific article published on 14 October 2020

Deciphering the role of heterozygous mutations in genes associated with parkinsonism

scientific article published on July 2007

Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease

scientific article published on 14 August 2006

Detection of oligomeric forms of alpha-synuclein protein in human plasma as a potential biomarker for Parkinson's disease

scientific article published on 01 March 2006

Detection of soluble forms of the beta-amyloid precursor protein in human plasma

scientific article published in March 1990

Development of electrochemiluminescence-based singleplex and multiplex assays for the quantification of α-synuclein and other proteins in cerebrospinal fluid ⬇️

scientific article published on March 23, 2012

Differential mobility spectrometry as an orthogonal separation to LC-ESI-MS/MS for quantification of isomeric cerebrosides in plasma and cerebrospinal fluid

article

Dimerization of Parkinson's disease-causing DJ-1 and formation of high molecular weight complexes in human brain

scientific article published in November 2004

Direct quantification of CSF alpha-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration

scientific article

Dopamine covalently modifies and functionally inactivates parkin

scientific article

Expansion of the Parkinson disease-associated SNCA-Rep1 allele upregulates human alpha-synuclein in transgenic mouse brain.

scientific article published on 04 June 2009

Fluid biomarkers in multiple system atrophy: A review of the MSA Biomarker Initiative.

scientific article published on 15 May 2015

GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein

scholarly article

Hashimoto's encephalopathy mimicking Creutzfeldt-Jakob disease: brain biopsy findings.

scientific article published in November 2002

Holocranohistochemistry enables the visualization of α-synuclein expression in the murine olfactory system and discovery of its systemic anti-microbial effects

scientific article

Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains

scientific article published on 25 February 2009

K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo.

scientific article published on 3 June 2016

LRRK2 and Nod2 promote lysozyme sorting in Paneth cells

scientific article published in August 2015

Lrrk2 alleles modulate inflammation during microbial infection of mice in a sex-dependent manner

scientific article published on 01 September 2019

Modelling idiopathic Parkinson disease as a complex illness can inform incidence rate in healthy adults: the PREDIGT score

scientific article (publication date: 27 December 2016)

Molecular markers of early Parkinson's disease based on gene expression in blood

scientific article

Multiple system atrophy: a primary oligodendrogliopathy.

scientific article published on September 2008

Mutant GBA1 expression and synucleinopathy risk: first insights from cellular and mouse models.

scientific article published on 09 February 2012

Nonmotor and diagnostic findings in subjects with de novo Parkinson disease of the DeNoPa cohort

scientific article

Novel one-step immunoassays to quantify α-synuclein: applications for biomarker development and high-throughput screening ⬇️

scientific article published on July 27, 2012

Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies

scientific article published on May 2002

Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1

scientific article

Parkinson disease, 10 years after its genetic revolution: multiple clues to a complex disorder

scientific article

Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures

scientific article

Parkinson's disease: assays for the ubiquitin ligase activity of neural Parkin

scientific article

Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease ⬇️

scientific article published on September 10, 2012

Protective effect of vagotomy suggests source organ for Parkinson disease

scientific article published on 22 September 2015

Quantification of α-synuclein in cerebrospinal fluid as a biomarker candidate: review of the literature and considerations for future studies

scientific article published on October 2010

RING finger 1 mutations in Parkin produce altered localization of the protein

scientific article published on 30 September 2003

Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting.

scientific article published on 13 December 2017

Respiratory infection of mice with mammalian reoviruses causes systemic infection with age and strain dependent pneumonia and encephalitis.

scientific article published on March 2013

Seizures after epidural blood patch

scientific article published on 01 January 2003

Serum heart-type fatty acid-binding protein and cerebrospinal fluid tau: marker candidates for dementia with Lewy bodies

scientific article

Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition

scientific article

The life of Eugene Braunwald: a remarkable journey that began in Vienna

scientific article published on January 16, 1998

Total CSF α-synuclein is lower in de novo Parkinson patients than in healthy subjects

scientific article published on 10 November 2012

Towards translational therapies for multiple system atrophy

scientific article

Unrecognized vitamin D3 deficiency is common in Parkinson disease: Harvard Biomarker Study

scientific article published on 25 September 2013

Vertebral artery dissection with a normal-appearing lumen at multisection CT angiography: the importance of identifying wall hematoma.

scientific article published on 22 January 2009

beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.

scientific article published on February 1993

α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study

scientific article published on March 2011

α-Synuclein in human cerebrospinal fluid is principally derived from neurons of the central nervous system

scientific article

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