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List of works by Simon Phipps

A role for eosinophils in airway remodelling in asthma

scientific article

Absence of Toll-IL-1 receptor 8/single immunoglobulin IL-1 receptor-related molecule reduces house dust mite-induced allergic airway inflammation in mice

scientific article

Absence of toll-like receptor 4 (TLR4) extends survival in the hSOD1 G93A mouse model of amyotrophic lateral sclerosis

scientific article published on 13 May 2015

Acute Allergen-Induced Airway Remodeling in Atopic Asthma

scientific article published on 27 August 2004

Aeroallergen-induced IL-33 predisposes to respiratory virus-induced asthma by dampening antiviral immunity

scientific article published on 25 April 2016

Allergen-induced IL-6 trans-signaling activates γδ T cells to promote type 2 and type 17 airway inflammation.

scientific article published on 28 April 2015

Allergic sensitization is enhanced in early life through toll-like receptor 7 activation

scientific article published on 03 September 2009

Anterograde neuronal circuit tracing using a genetically modified herpes simplex virus expressing EGFP.

scientific article

Antigen-specific T-cell responses to a recombinant fowlpox virus are dependent on MyD88 and interleukin-18 and independent of Toll-like receptor 7 (TLR7)- and TLR9-mediated innate immune recognition

scientific article published on 19 January 2011

Asthma is associated with multiple alterations in anti-viral innate signalling pathways

scientific article

Bone Marrow Regulatory T Cells Are a Unique Population, Supported by Niche-Specific Cytokines and Plasmacytoid Dendritic Cells, and Required for Chronic Graft-Versus-Host Disease Control

scientific article published on 22 September 2021

Coinfection with Blood-Stage Plasmodium Promotes Systemic Type I Interferon Production during Pneumovirus Infection but Impairs Inflammation and Viral Control in the Lung

scientific article published on 25 February 2015

Early production of thymic stromal lymphopoietin precedes infiltration of dendritic cells expressing its receptor in allergen-induced late phase cutaneous responses in atopic subjects

article

Elevated expression of the NLRP3 inflammasome in neutrophilic asthma

scientific article

Eosinophil trafficking in allergy and asthma.

scientific article published on 3 May 2007

Eosinophils: biological properties and role in health and disease

scientific article published in April 2008

Evaluating vaccinia virus cytokine co-expression in TLR GKO mice.

scientific article published on 21 December 2010

Evidence that opioids may have toll-like receptor 4 and MD-2 effects

scientific article

Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity

scientific article

IRF-3, IRF-7, and IPS-1 promote host defense against acute human metapneumovirus infection in neonatal mice

scientific article published on 13 April 2014

Immunomodulation of airway epithelium cell activation by mesenchymal stromal cells ameliorates house dust mite-induced airway inflammation in mice

scientific article published on 19 March 2015

Inflammatory mechanisms and treatment of obstructive airway diseases with neutrophilic bronchitis.

scientific article published on 22 June 2009

Intravenous anti-IL-5 monoclonal antibody reduces eosinophils and tenascin deposition in allergen-challenged human atopic skin

scientific article published in June 2004

Mice deficient in heparanase exhibit impaired dendritic cell migration and reduced airway inflammation

scientific article published on 14 February 2014

Microarray Analysis of Eosinophils Reveals a Number of Candidate Survival and Apoptosis Genes ⬇️

scientific article published on October 1, 2001

NK Cell Deficiency Predisposes to Viral-Induced Th2-Type Allergic Inflammation via Epithelial-Derived IL-25

scientific article published on 20 September 2010

PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-λ production.

scientific article

Plasmacytoid dendritic cells promote host defense against acute pneumovirus infection via the TLR7-MyD88-dependent signaling pathway

scientific article

Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion

scientific article published on 22 December 2017

Pulmonary eosinophils and their role in immunopathologic responses to formalin-inactivated pneumonia virus of mice.

scientific article published on July 2009

RAGE and TLRs: relatives, friends or neighbours?

scientific article published on 14 August 2013

RAGE deficiency predisposes mice to virus-induced paucigranulocytic asthma

scientific article published on 18 January 2017

RAGE: a new frontier in chronic airways disease

scientific article

Receptor for advanced glycation end products and its ligand high-mobility group box-1 mediate allergic airway sensitization and airway inflammation

scientific article published on 4 February 2014

Regulation of inducible BALT formation and contribution to immunity and pathology.

scientific article published on September 2010

Regulatory T cells prevent inducible BALT formation by dampening neutrophilic inflammation.

scientific article published on 25 March 2015

Sensorimotor circuitry involved in the higher brain control of coughing

scientific article published on 6 March 2013

Soluble heparan sulfate fragments generated by heparanase trigger the release of pro-inflammatory cytokines through TLR-4.

scientific article

TLR2, but not TLR4, is required for effective host defence against Chlamydia respiratory tract infection in early life.

scientific article

Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication

scientific article published on 24 May 2021

Th2/Th17 reciprocal regulation: twists and turns in the complexity of asthma phenotypes

scientific article

The Influence of the Microbiome on Early-Life Severe Viral Lower Respiratory Infections and Asthma-Food for Thought?

scientific article published on 16 February 2017

The Relationship Between Allergen-Induced Tissue Eosinophilia and Markers of Repair and Remodeling in Human Atopic Skin

scientific article published on 01 October 2002

The contribution of toll-like receptors to the pathogenesis of asthma

scientific article published on 7 August 2007

The effect of hyperpolarization-activated cyclic nucleotide-gated ion channel inhibitors on the vagal control of guinea pig airway smooth muscle tone

scientific article

The plasmacytoid dendritic cell: at the cross-roads in asthma

scientific article published on 21 February 2013

The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization.

scientific article published on 21 May 2013

Toll-like receptor 7 gene deficiency and early-life Pneumovirus infection interact to predispose toward the development of asthma-like pathology in mice

scientific article published on 2 April 2013

Toll-like receptor 7 governs interferon and inflammatory responses to rhinovirus and is suppressed by IL-5-induced lung eosinophilia.

scientific article

Toll/IL-1 signaling is critical for house dust mite-specific helper T cell type 2 and type 17 [corrected] responses.

scientific article published on 26 February 2009

Viral and host factors determine innate immune responses in airway epithelial cells from children with wheeze and atopy

scientific article

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