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List of works by Ronald P. Hart

5' End Nicotinamide Adenine Dinucleotide Cap in Human Cells Promotes RNA Decay through DXO-Mediated deNADding.

scientific article

A comparison of substance P peptide and preprotachykinin mRNA levels during development of rat medullary raphe and neostriatum

scientific article published in January 1991

A high-resolution molecular-based panel of assays for identification and characterization of human embryonic stem cell lines.

scientific article

A positive feedback mechanism that regulates expression of miR-9 during neurogenesis

scientific article

ATM is activated by ATP depletion and modulates mitochondrial function through NRF1

scientific article published on 14 January 2019

Activated Notch1 maintains the phenotype of radial glial cells and promotes their adhesion to laminin by upregulating nidogen.

scientific article

Activation of acidic sphingomyelinase and protein kinase C zeta is required for IL-1 induction of LIF mRNA in a Schwann cell line

scientific article published on September 1996

Addiction associated N40D mu-opioid receptor variant modulates synaptic function in human neurons

scientific article published on 03 September 2019

Adjuvant chemotherapy in older women with early-stage breast cancer

scientific article

Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors.

scientific article

Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons

Alteration in 5-hydroxymethylcytosine-mediated epigenetic regulation leads to Purkinje cell vulnerability in ATM deficiency

scientific article

Alterations of preprotachykinin (PPT) mRNA in medullary raphe occur following manipulation of serotonin

scientific article published on 01 January 1991

An mRNA homologous to interleukin-1 receptor type I is expressed in cultured rat sympathetic ganglia

scientific article published in April 1993

Analyses of the autism-associated neuroligin-3 R451C mutation in human neurons reveal a gain-of-function synaptic mechanism

Association of aberrant DNA methylation in Apc(min/+) mice with the epithelial-mesenchymal transition and Wnt/β-catenin pathways: genome-wide analysis using MeDIP-seq

scientific article published on 27 May 2015

Bioinformatic Analysis of DNA Methylation in Neural Progenitor Cell Models of Alcohol Abuse.

scientific article

Both zimelidine and clorgyline decrease preprotachykinin mRNA in adult medullary raphe nuclei

scientific article

Characterization of spinal HSP72 induction and development of ischemic tolerance after spinal ischemia in rats

scientific article

Cloning and characterization of an alternatively processed human type II interleukin-1 receptor mRNA.

scientific article

Comparison of microarray and quantitative real-time PCR methods for measuring MicroRNA levels in MSC cultures.

scientific article published on January 2011

Compartmentalized Devices as Tools for Investigation of Human Brain Network Dynamics

scientific article published on 12 September 2018

Concise review: MicroRNA expression in multipotent mesenchymal stromal cells.

scientific article published on 8 November 2007

Cultured sympathetic neurons express functional interleukin-1 receptors

scientific article published on 01 November 1998

Cysteine- and glycine-rich protein 1a is involved in spinal cord regeneration in adult zebrafish

scientific article

Cytokine activity contributes to induction of inflammatory cytokine mRNAs in spinal cord following contusion.

scientific article

DMRfinder: efficiently identifying differentially methylated regions from MethylC-seq data

scientific article published on 29 November 2017

DNA methylome and transcriptome alterations and cancer prevention by curcumin in colitis-accelerated colon cancer in mice.

scientific article published on 14 March 2018

Development of a high-throughput arrayed neural circuitry platform using human induced neurons for drug screening applications

scientific article published on 01 March 2020

Development of substance P (SP)-containing cells in the central nervous system: consequences of neurotransmitter co-localization.

scientific article published on January 1991

Differential regulation of microRNA stability

scientific article

Differential sensitivity of human neurons carrying μ opioid receptor (MOR) N40D variants in response to ethanol

scientific article published on 16 June 2020

Differentiating human multipotent mesenchymal stromal cells regulate microRNAs: prediction of microRNA regulation by PDGF during osteogenesis

scientific article published on 26 July 2008

EZH2-mediated H3K27 trimethylation mediates neurodegeneration in ataxia-telangiectasia

scientific article

Effects of DDT on Amyloid Precursor Protein Levels and Amyloid Beta Pathology: Mechanistic Links to Alzheimer's Disease Risk

scientific article published in 2022

Effects of Lymphokines on Substance P in Injured Ganglia of the Peripheral Nervous System

scientific article published on January 1, 1991

Efficient, high-throughput transfection of human embryonic stem cells

scientific article

Elevated Choline Kinase α-Mediated Choline Metabolism Supports the Prolonged Survival of TRAF3-Deficient B Lymphocytes

scientific article published on 11 December 2019

Epigenetic alterations in TRAMP mice: epigenome DNA methylation profiling using MeDIP-seq

scientific article published on 12 January 2018

Epigenome analysis of pluripotent stem cells.

scientific article published on January 2013

Erratum to: The impact of glutamine supplementation on the symptoms of ataxia-telangiectasia: a preclinical assessment.

scientific article published on 12 January 2017

Erratum: Corrigendum: EZH2-mediated H3K27 trimethylation mediates neurodegeneration in ataxia-telangiectasia

correction of a scholarly article

Ethanol-mediated activation of the NLRP3 inflammasome in iPS cells and iPS cells-derived neural progenitor cells

scientific article published on 10 May 2016

Evaluation of sense-strand mRNA amplification by comparative quantitative PCR

scientific article

Expression of NK-1 receptor mRNA in murine T lymphocytes

Expression profiling of synaptic microRNAs from the adult rat brain identifies regional differences and seizure-induced dynamic modulation

scientific article published on 9 December 2011

Flipping the transcriptional switch from myelin inhibition to axon growth in the CNS.

scientific article published on 17 July 2015

Functional differentiation of a clone resembling embryonic cortical interneuron progenitors

scientific article published on December 2008

Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds

scientific article

Genetics of Alcohol Use Disorder: A Role for Induced Pluripotent Stem Cells?

article

Genome-wide admixture mapping of DSM-IV alcohol dependence, criterion count, and the self-rating of the effects of ethanol in African American populations

scientific article published on 11 July 2020

Genome-wide analysis of DNA methylation in UVB- and DMBA/TPA-induced mouse skin cancer models

scientific article published on 2 August 2014

Genome-wide analysis reveals methyl-CpG-binding protein 2-dependent regulation of microRNAs in a mouse model of Rett syndrome

scientific article

Histone acetylation maps in aged mice developmentally exposed to lead: epigenetic drift and Alzheimer-related genes.

scientific article published on 3 May 2018

Human iPSC-derived mature microglia retain their identity and functionally integrate in the chimeric mouse brain

scientific article published on 27 March 2020

Identification of mRNAs regulated by interferon-gamma in cultured rat astrocytes by PCR differential display.

scientific article published in November 1995

Immune cytokine regulation of sympathetic ganglion response to injury

scientific article published on July 1995

In vivo pharmacokinetics and regulation of gene expression profiles by isothiocyanate sulforaphane in the rat.

scientific article published on 26 February 2004

Increased nicotine response in iPSC-derived human neurons carrying the CHRNA5 N398 allele

scientific article

Intellicount: High-Throughput Quantification of Fluorescent Synaptic Protein Puncta by Machine Learning.

scientific article published in November 2017

Interferon-gamma promotes cholinergic differentiation of embryonic septal nuclei and adjacent basal forebrain

scientific article

Interleukin-1 beta increases leukemia inhibitory factor mRNA levels through transient stimulation of transcription rate

scientific article published on October 1996

Interleukin-1 induces substance P in sympathetic ganglia through the induction of leukemia inhibitory factor (LIF)

scientific article published on 01 June 1993

Interleukin-1 involvement in the induction of leukemia inhibitory factor mRNA expression following axotomy of sympathetic ganglia

scientific article published in November 1996

Interleukin-1 specifically increases substance P in injured sympathetic ganglia

scientific article published on 01 January 1990

Intrinsic differences in brain and spinal cord mitochondria: Implication for therapeutic interventions.

scientific article

Isolation of a novel rat neural progenitor clone that expresses Dlx family transcription factors and gives rise to functional GABAergic neurons in culture

scientific article published on June 2012

Knockdown of Butyrylcholinesterase but Not Inhibition by Chlorpyrifos Alters Early Differentiation Mechanisms in Human Neural Stem Cells

article

Lipopolysaccharide induces substance P in sympathetic ganglia via ganglionic interleukin-1 production.

scientific article

Localisation of mRNA for interleukin-1 receptor and interleukin-1 receptor antagonist in the rat ovary

scientific article published in January 1997

Long noncoding RNAs: Central to nervous system development.

scientific article published on 10 June 2016

Low-Density Lipoprotein Receptor-Related Protein 6 Cell Surface Availability Regulates Fuel Metabolism in Astrocytes

scientific article published on 27 June 2021

Mechanisms of colitis-accelerated colon carcinogenesis and its prevention with the combination of aspirin and curcumin: Transcriptomic analysis using RNA-seq.

scientific article published on 3 March 2017

Mediators of ischemic preconditioning identified by microarray analysis of rat spinal cord

scientific article published on 01 January 2004

Metallothionein-I/II Promotes Axonal Regeneration in the Central Nervous System

scientific article published on 6 May 2015

MicroRNA expression pattern of undifferentiated and differentiated human embryonic stem cells

scientific article published on December 2007

MicroRNA miR-133b is essential for functional recovery after spinal cord injury in adult zebrafish

scientific article

Microtubules are critical for radial glial morphology: possible regulation by MAPs and MARKs.

scientific article published on October 2003

Molecular control of physiological and pathological T-cell recruitment after mouse spinal cord injury

scientific article

Multiple knockout mouse models reveal lincRNAs are required for life and brain development

scientific article (publication date: 31 December 2013)

Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphocytes

scientific article

Neural progenitors derived from Tuberous Sclerosis Complex patients exhibit attenuated PI3K/AKT signaling and delayed neuronal differentiation

scientific article published on 23 August 2018

Neurochemical development of the raphe after continuous prenatal cocaine exposure

scientific article published in January 1993

Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia

scientific article

Nudt3 is an mRNA decapping enzyme that modulates cell migration

scientific article published on March 2016

OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome

scientific article published on 23 May 2019

Optimized splitting of mixed-species RNA sequencing data

scientific article published on 06 January 2022

Optogenetic and transcriptomic interrogation of enhanced muscle function in the paralyzed mouse whisker pad

scientific article published on 20 February 2019

Optogenetic and transcriptomic interrogation of enhanced muscle function in the paralyzed mouse whisker pad

preprint

Pathological CNS autoimmune disease triggered by traumatic spinal cord injury: implications for autoimmune vaccine therapy.

scientific article published on April 2002

Poly(A) site cleavage in a HeLa nuclear extract is dependent on downstream sequences.

scientific article

Post-transcriptional control of tryptophan hydroxylase gene expression in rat brain stem and pineal gland

scientific article published in February 1991

Post-transcriptional regulatory elements and spatiotemporal specification of neocortical stem cells and projection neurons.

scientific article published on 30 May 2013

Protective autoimmunity: interferon-gamma enables microglia to remove glutamate without evoking inflammatory mediators.

scientific article

Randomized Trial of Standard Adjuvant Chemotherapy Regimens Versus Capecitabine in Older Women With Early Breast Cancer: 10-Year Update of the CALGB 49907 Trial

scientific article published on 24 July 2019

Rapid induction of genes associated with tissue protection and neural development in contused adult spinal cord after radial glial cell transplantation

scientific article

Rapid preparation of Thermus flavus DNA polymerase

scientific article published on 01 June 1994

Rational probe optimization and enhanced detection strategy for microRNAs using microarrays

scientific article published on 20 July 2005

SCI-Base: an open-source spinal cord injury animal experimentation database

scientific article published on March 2004

Screening anti-inflammatory compounds in injured spinal cord with microarrays: a comparison of bioinformatics analysis approaches.

scientific article published on 13 April 2004

Secretory leukocyte protease inhibitor reverses inhibition by CNS myelin, promotes regeneration in the optic nerve, and suppresses expression of the transforming growth factor-β signaling protein Smad2.

scientific article published on March 2013

Sequences capable of restoring poly(A) site function define two distinct downstream elements.

scientific article published on November 1986

Serotonin innervation affects SP biosynthesis in rat neostriatum

scientific article published in January 1991

Serotonin modulates the levels of mRNAS coding for thyrotropin-releasing hormone and preprotachykinin by different mechanisms in medullary raphe neurons

scientific article published in March 1993

Serotonin regulation of neostriatal tachykinins following neonatal 6-hydroxydopamine lesions

scientific article published in August 1991

Serotonin regulation of tachykinin biosynthesis in the rat neostriatum

scientific article

Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury

scientific article

Species-specific activity of rat recombinant interleukin-1 beta

scientific journal article

Spontaneous ATM Gene Reversion in A-T iPSC to Produce an Isogenic Cell Line.

scientific article

Structural and mechanistic basis of mammalian Nudt12 RNA deNADding

scientific article published on 17 May 2019

Structure and organization of a mammalian 5 S gene cluster

scientific article published in October 1982

Substance P gene expression is regulated by interleukin-1 in cultured sympathetic ganglia

scientific article published on 01 July 1991

Synaptic mechanism of A118G OPRM1 Gene Variants In Human Neurons

Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R.

scientific article published on 25 August 2014

Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes.

scientific article published in August 2015

The Amyloid Precursor Protein Modulates the Position and Length of the Axon Initial Segment

The RNA binding protein HuR determines the differential translation of autism-associated FoxP subfamily members in the developing neocortex

scientific article published on 07 July 2016

The cytokine interleukin-6 is sufficient but not necessary to mimic the peripheral conditioning lesion effect on axonal growth.

scientific article published in May 2006

The impact of glutamine supplementation on the symptoms of ataxia-telangiectasia: a preclinical assessment

scientific article published on 18 August 2016

The interleukin-1-induced increase of substance P in sympathetic ganglia is not mediated by ciliary neurotrophic factor

scientific article published on 01 August 1994

Tissue inhibitor of metalloproteinases-1 stimulates gene expression in MDA-MB-435 human breast cancer cells by means of its ability to inhibit metalloproteinases

scientific article published on November 2005

Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury

scientific article published on 30 March 2007

Top2b is involved in the formation of outer segment and synapse during late-stage photoreceptor differentiation by controlling key genes of photoreceptor transcriptional regulatory network

scientific article

Transcription factor Sox11b is involved in spinal cord regeneration in adult zebrafish.

scientific article published on 15 October 2010

Transcriptomic profiling of splenic B lymphomas spontaneously developed in B cell-specific TRAF3-deficient mice

scientific article

Translational derepression of Elavl4 isoforms at their alternative 5' UTRs determines neuronal development

scientific article published on 03 April 2020

Tryptophan hydroxylase inhibition increases preprotachykinin mRNA in developing and adult medullary raphe nuclei

scientific article published on July 1990

Tumor necrosis factor-alpha induces substance P in sympathetic ganglia through sequential induction of interleukin-1 and leukemia inhibitory factor

scientific article published on 01 December 1995

Vasoactive intestinal peptide and pituitary adenylyl cyclase-activating polypeptide inhibit tumor necrosis factor-alpha production in injured spinal cord and in activated microglia via a cAMP-dependent pathway

scientific article published on 01 May 2000

hsa-let-7c miRNA Regulates Synaptic and Neuronal Function in Human Neurons

scientific article published on 17 July 2018

mRNA-Decapping Associated DcpS Enzyme Controls Critical Steps of Neuronal Development

miR-886-3p levels are elevated in Friedreich ataxia.

scientific article

miRNA in pluripotent stem cells

scientific article published on July 2010

μNeurocircuitry: Establishing in vitro models of neurocircuits with human neurons.

scientific article published in June 2017