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List of works by M Prakash Hande

A Child with Partial Trisomy 4 (q26 - qterminal) Resulting from Paternally Inherited Translocation (4:18) Associated with Multiple Congenital Anomalies and Death

scientific article published on 24 May 2019

A comparative study of protein kinase C activation in gamma-irradiated proliferating and confluent human lung fibroblast cells

scientific article published on 14 July 2009

A positive role for c-Abl in Atm and Atr activation in DNA damage response.

scientific article

A role for Brca1 in chromosome end maintenance

scientific article published on 30 January 2006

A role for Mus81 in the repair of chromium-induced DNA damage

scientific article published in January 2009

Age-independent telomere shortening and ion-channel defects in SCD

scientific article published on 30 April 2013

Analysis of telomere damage by fluorescence in situ hybridisation on micronuclei in lymphocytes of breast carcinoma patients after radiotherapy

scientific article

Annexin-1 protects MCF7 breast cancer cells against heat-induced growth arrest and DNA damage

scientific article published in August 2010

Anti-proliferative activity of silver nanoparticles

scientific article published on 17 September 2009

Assessment of genomic instability and proliferation index in cultured lymphocytes of patients with Down syndrome, congenital anomalies and aplastic anaemia

Assignment of hexokinase types 1,2,3 (Hk1,2,3) and glucokinase (Gck) to rat chromosome band 20q11, 4q34, 17q12 and 14q21 respectively, by in situ hybridization

scientific article published in January 1997

Biochemical response of diverse organs in adult Danio rerio (zebrafish) exposed to sub-lethal concentrations of microcystin-LR and microcystin-RR: a balneation study

scientific article

Biomarkers Specific to Densely-ionising (High LET) Radiations

scientific article published in September 2001

Biomarkers of Ionizing Radiation Exposure: A Multiparametric Approach

scientific article published on 23 January 2017

Book Review: Toxicogenomics in Predictive Carcinogenicity.

scientific article

Characterization of ataxia telangiectasia fibroblasts with extended life-span through telomerase expression.

scientific article published on January 2001

Chromosomal instability--mechanisms and consequences

scientific article published on 28 August 2015

Chromosomal rearrangements involving telomeric DNA sequences in Balb/3T3 cells transfected with the Ha-ras oncogene.

scientific article

Clinico-Pathological Correlation of β-Catenin and Telomere Dysfunction in Head and Neck Squamous Cell Carcinoma Patients

scientific article published on 15 January 2015

Collaboration of Brca1 and Chk2 in tumorigenesis

scientific article

Combined treatment with cisplatin and the tankyrase inhibitor XAV-939 increases cytotoxicity, abrogates cancer-stem-like cell phenotype and increases chemosensitivity of head-and-neck squamous-cell carcinoma cells

scientific article published on 17 August 2019

Complex chromosome aberrations persist in individuals many years after occupational exposure to densely ionizing radiation: an mFISH study

scientific article published in September 2005

Consecutive maintenance of human solitary and hereditary colorectal polyps in SCID mice.

scientific article published in January 1997

Cooperation of Blm and Mus81 in development, fertility, genomic integrity and cancer suppression

scientific article published on 26 May 2014

Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo

scientific article published on 10 September 2010

Correlation of cord blood telomere length with birth weight

scientific article published on 8 September 2017

Curcumin inhibits telomerase and induces telomere shortening and apoptosis in brain tumour cells ⬇️

scientific article published on June 1, 2013

Current cytogenetic methods for detecting exposure and effects of mutagens and carcinogens

scientific article

DNA damage and p53-mediated growth arrest in human cells treated with platinum nanoparticles

article published in 2010

DNA repair factors and telomere-chromosome integrity in mammalian cells.

scientific article published on January 2004

DNA-PKcs is critical for telomere capping

scientific article

DNA-dependent protein kinase modulates the anti-cancer properties of silver nanoparticles in human cancer cells

scientific article published on 13 October 2017

Deciphering the structure and function of FcεRI/mast cell axis in the regulation of allergy and anaphylaxis: a functional genomics paradigm.

scientific article published on 07 December 2011

Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality

scientific article published in August 2004

Derivation efficiency, cell proliferation, freeze-thaw survival, stem-cell properties and differentiation of human Wharton's jelly stem cells.

scientific article published on 24 April 2010

Differential regulation of intracellular factors mediating cell cycle, DNA repair and inflammation following exposure to silver nanoparticles in human cells

scientific article published on 10 February 2012

Differential resistance of human embryonic stem cells and somatic cell types to hydrogen peroxide-induced genotoxicity may be dependent on innate basal intracellular ROS levels

scientific article published on 9 July 2015

Distribution pattern of cytoplasmic organelles, spindle integrity, oxidative stress, octamer-binding transcription factor 4 (Oct4) expression and developmental potential of oocytes following multiple superovulation

scientific article

Ectopic mTERT expression in mouse embryonic stem cells does not affect differentiation but confers resistance to differentiation- and stress-induced p53-dependent apoptosis

scientific article published on 25 January 2005

Effect of fetal exposure to ultrasound on the behavior of the adult mouse

scientific article published in March 1995

Effect of in utero exposure to diagnostic ultrasound on the postnatal survival and growth of mouse

scientific article published in November 1993

Effect of prenatal exposure to diagnostic ultrasound on the development of mice

scientific article published in April 1992

Effect of prenatal ultrasound exposure on adult behavior in mice

scientific article published in November 1993

Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells

scientific article published in August 2001

Effects of an integrated yoga program in modulating psychological stress and radiation-induced genotoxic stress in breast cancer patients undergoing radiotherapy

scientific article published in September 2007

Effects of rapamycin on the mechanistic target of rapamycin (mTOR) pathway and telomerase in breast cancer cells

scientific article published on 28 March 2018

Elongated Telomeres inscidMice

scientific article published in March 1999

Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells

scientific article

Enhanced genotoxicity of silver nanoparticles in DNA repair deficient Mammalian cells

scientific article published on 13 June 2012

Environmental toxicogenomics: a post-genomic approach to analysing biological responses to environmental toxins.

scientific article published on 29 October 2009

Evaluation of human embryonic stem cells and their differentiated fibroblastic progenies as cellular models for in vitro genotoxicity screening

scientific article published on 23 May 2014

Extra-chromosomal telomeric DNA in cells from Atm-/- mice and patients with ataxia-telangiectasia

scientific article published in March 2001

Folate deficiency induces dysfunctional long and short telomeres; both states are associated with hypomethylation and DNA damage in human WIL2-NS cells

scientific article published on 19 November 2013

Folate deficiency is associated with the formation of complex nuclear anomalies in the cytokinesis-block micronucleus cytome assay

scientific article published on 19 March 2012

Functional Interplay of p53 and Mus81 in DNA Damage Responses and Cancer

scientific article published on 15 September 2007

Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability

scientific article published in September 1999

Genistein induces growth arrest and suppresses telomerase activity in brain tumor cells

scientific article published on 27 June 2012

Genome Integrity - a new open access journal.

scientific article published on 26 May 2010

Genome-Wide Transcriptome Analysis Reveals Intermittent Fasting-Induced Metabolic Rewiring in the Liver

scientific article published on 01 July 2019

Genomic imbalances in key ion channel genes and telomere shortening in sudden cardiac death victims

scientific article published in January 2008

Genomic instability of gold nanoparticle treated human lung fibroblast cells.

scientific article

Genomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndrome

scientific article

Health impact and safety of engineered nanomaterials

scientific article published on 11 April 2011

Human embryonic stem cells may display higher resistance to genotoxic stress as compared to primary explanted somatic cells.

scientific article published in June 2008

Hydrogen peroxide induced genomic instability in nucleotide excision repair-deficient lymphoblastoid cells

scientific article published on 22 December 2010

Induction and persistence of cytogenetic damage in mouse splenocytes following whole-body X-irradiation analysed by fluorescence in situ hybridization. II. Micronuclei

scientific article published in October 1996

Induction and persistence of cytogenetic damage in mouse splenocytes following whole-body X-irradiation analysed by fluorescence in situ hybridization. III. Chromosome malsegregation/aneuploidy

scientific article published in 1997

Induction and persistence of cytogenetic damage in mouse splenocytes following whole-body X-irradiation analysed by fluorescence in situ hybridization. IV. Dose response.

scientific article

Induction of cancer, actinic keratosis, and specific p53 mutations by UVB light in human skin maintained in severe combined immunodeficient mice.

scientific article

Induction of telomerase activity and chromosome aberrations in human tumour cell lines following X-irradiation.

scientific article published on June 1998

Induction of telomerase activity by UV-irradiation in Chinese hamster cells

scientific article published in October 1997

Induction of telomerase activity by in vivo X-irradiation of mouse splenocytes and its possible role in chromosome healing

scientific article published in August 1998

Inhibition of poly (ADP-Ribose) polymerase-1 in telomerase deficient mouse embryonic fibroblasts increases arsenite-induced genome instability

scientific article

Inhibition of telomerase activity and human telomerase reverse transcriptase gene expression by histone deacetylase inhibitor in human brain cancer cells

scientific article published on 26 June 2007

Involvement of mammalian Mus81 in genome integrity and tumor suppression

scientific article published in June 2004

Isoform-specific activation of protein kinase c in irradiated human fibroblasts and their bystander cells

scientific article published on 18 July 2007

Lack of poly(ADP-ribose) polymerase-1 gene product enhances cellular sensitivity to arsenite

scientific article published in December 2005

Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity

scientific journal article

Loss of Brca2 and p53 synergistically promotes genomic instability and deregulation of T-cell apoptosis

scientific article published on 01 November 2002

MST-312 Alters Telomere Dynamics, Gene Expression Profiles and Growth in Human Breast Cancer Cells

scientific article published on January 2014

Massively parallel single-molecule telomere length measurement with digital real-time PCR

scientific article published on 21 August 2020

Mechanisms of induction of chromosomal aberrations and their detection by fluorescence in situ hybridization

scientific article published in December 1996

Mimosine is a potent clastogen in primary and transformed hamster fibroblasts but not in primary or transformed human lymphocytes.

scientific article

Morphology and function of human benign tumors and normal thyroid tissues maintained in severe combined immunodeficient mice

scientific article published in October 1998

Oxidative damage induced genotoxic effects in human fibroblasts from Xeroderma Pigmentosum group A patients

scientific article published on 21 May 2008

Past exposure to densely ionizing radiation leaves a unique permanent signature in the genome

scientific article published on 4 April 2003

Physicochemical and toxicological characteristics of urban aerosols during a recent Indonesian biomass burning episode.

scientific article published on 13 September 2012

Plumbagin alters telomere dynamics, induces DNA damage and cell death in human brain tumour cells

scientific article published on 9 June 2015

Plumbagin triggers DNA damage response, telomere dysfunction and genome instability of human breast cancer cells

scientific article published on 14 May 2016

Prediction of the Acute or Late Radiation Toxicity Effects in Radiotherapy Patients Using Ex Vivo Induced Biodosimetric Markers: A Review

scientific article published on 16 December 2020

Predictive Genomics: A Post-genomic Integrated Approach to Analyse Biological Signatures of Radiation Exposure

Progressive loss of epidermal growth factor receptor in a subpopulation of breast cancers: implications in target-directed therapeutics

scientific article published on 7 November 2007

RENEB intercomparisons applying the conventional Dicentric Chromosome Assay (DCA).

scientific article published on 21 October 2016

Rad54 and Mus81 cooperation promotes DNA damage repair and restrains chromosome missegregation

scientific article published on 15 February 2016

Rad54 is dispensable for the ALT pathway

scientific article published in November 2006

Routine screening mammography: how important is the radiation-risk side of the benefit-risk equation?

scientific article published on December 2002

Short dysfunctional telomeres impair the repair of arsenite-induced oxidative damage in mouse cells.

scientific article published in March 2008

Specific role of Chk1 phosphorylations in cell survival and checkpoint activation

scientific article published on 22 January 2007

Stable expression of promyelocytic leukaemia (PML) protein in telomerase positive MCF7 cells results in alternative lengthening of telomeres phenotype

scientific article published on 27 August 2012

Stable intrachromosomal biomarkers of past exposure to densely ionizing radiation in several chromosomes of exposed individuals

scientific article

Strengthening Biological Dosimetry in Member States of the International Atomic Energy Agency.

scientific article published on 30 December 2016

Synergistic interaction of Rnf8 and p53 in the protection against genomic instability and tumorigenesis.

scientific article

TAp73 Is a Downstream Target of p53 in Controlling the Cellular Defense against Stress

scientific article published in Journal of Biological Chemistry

Targeting DNA-PKcs and telomerase in brain tumour cells

scientific article

Telomerase-associated protein TEP1 is not essential for telomerase activity or telomere length maintenance in vivo

scientific article (publication date: November 2000)

Telomere Biology-Insights into an Intriguing Phenomenon.

scientific article

Telomere and Telomerase Modulation by the Mammalian Rad9/Rad1/Hus1 DNA-Damage-Checkpoint Complex

scientific article published in August 2006

Telomere attrition and genomic instability in xeroderma pigmentosum type-b deficient fibroblasts under oxidative stress

scientific article published on 16 October 2009

Telomere length regulation in mice is linked to a novel chromosome locus.

scientific article

Telomere length, chromatin structure and chromosome fusigenic potential ⬇️

scientific article published on December 1, 1997

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

scientific article (publication date: 3 October 1997)

Telomere-mediated chromosomal instability triggers TLR4 induced inflammation and death in mice

scientific article

Telomere-mediated genomic instability and the clinico-pathological parameters in breast cancer

scientific article

Teratogenic effect of hyperthermia during early organogenesis period in mice

scientific article published in January 1993

Teratogenic effects of repeated exposures to X-rays and/or ultrasound in mice

scientific article published in March 1995

The difference in LET and ion species dependence for induction of initially measured and non-rejoined chromatin breaks in normal human fibroblasts

scientific article published in August 2008

The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo.

scientific article published on November 2000

Thymoquinone induces telomere shortening, DNA damage and apoptosis in human glioblastoma cells

scientific article

Toxicological profile of small airway epithelial cells exposed to gold nanoparticles.

scientific article published on 24 October 2013

Trans-dichlorooxovandium (IV) complex as a novel photoinducible DNA interstrand crosslinker for cancer therapy.

scientific article published on 17 December 2015

Tumor cell redox state and mitochondria at the center of the non-canonical activity of telomerase reverse transcriptase.

scientific article published on 06 December 2009

UHRF1 is a genome caretaker that facilitates the DNA damage response to gamma-irradiation

scientific article

Yeast Nhp6A/B and mammalian Hmgb1 facilitate the maintenance of genome stability

scientific article published in January 2005

Zika virus alters DNA methylation status of genes involved in Hippo signaling pathway in human neural progenitor cells

scientific article published on 25 June 2019

Zinc oxide nanoparticles exhibit cytotoxicity and genotoxicity through oxidative stress responses in human lung fibroblasts and Drosophila melanogaster

scientific article (publication date: 28 February 2017)

c-Jun N-terminal kinase mediates hydrogen peroxide-induced cell death via sustained poly(ADP-ribose) polymerase-1 activation

scientific article published on 12 January 2007

hTERT Overexpression Alleviates Intracellular ROS Production, Improves Mitochondrial Function, and Inhibits ROS-Mediated Apoptosis in Cancer Cells ⬇️

scientific article published on November 11, 2010

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