List of works - Qinwen Mao

A Fiber Chimeric CRAd Vector Ad5/11-D24 Double-Armed with TRAIL and Arresten for Enhanced Glioblastoma Therapy ⬇️

scientific article published on May 14, 2012

A Highly Sensitive Sandwich ELISA to Detect CSF Progranulin: A Potential Biomarker for CNS Disorders

scientific article published on 01 May 2019

A dorsally located giant posterior fossa neurenteric cyst in a Chinese woman

scientific article published on 20 March 2015

A knock-in reporter model of Batten disease

scientific article published on 01 September 2007

A mouse model of classical late-infantile neuronal ceroid lipofuscinosis based on targeted disruption of the CLN2 gene results in a loss of tripeptidyl-peptidase I activity and progressive neurodegeneration

scientific journal article

A novel Ad5/11 chimeric oncolytic adenovirus for improved glioma therapy.

scientific article

A novel adenoviral vector carrying an all-in-one Tet-On system with an autoregulatory loop for tight, inducible transgene expression.

scientific article

A novel conditionally replicating adenoviral vector with dual expression of IL-24 and arresten inserted in E1 and the region between E4 and fiber for improved melanoma therapy.

scientific article

A novel luciferase knock-in reporter system for studying transcriptional regulation of the human Sox2 gene.

scientific article

A novel system for rapid screening of effective siRNA target sites by one step transfection with a single vector.

scientific article published on 25 June 2011

A novel vector for a rapid generation of fiber-mutant adenovirus based on one step ligation and quick screening of positive clones ⬇️

scientific article published on February 12, 2011

A one-step ligation system for rapid generation of armed, conditionally-replicating adenoviruses ⬇️

scientific article published on April 23, 2013

A rapid generation of adenovirus vector with a genetic modification in hexon protein

scientific article published on 29 December 2011

A simple, efficient and economical method for isolating and culturing human umbilical cord blood‑derived mesenchymal stromal cells

scientific article published on 23 October 2019

A targeting peptide improves adenovirus-mediated transduction of a glioblastoma cell line

scientific article

Accreditation Council for Graduate Medical Education Self-Study for Pathology: One Institution's Experience and Lessons Learned

scientific article published on 24 April 2019

Adult polyglucosan body disease with GBE1 haploinsufficiency and concomitant frontotemporal lobar degeneration

scientific article

Aptamer modification improves the adenoviral transduction of malignant glioma cells.

scientific article published on 24 October 2013

Aptazyme-mediated direct modulation of post-transcriptional sgRNA level for conditional genome editing and gene expression

article

Biological function analysis of monoclonal antibodies against human granulins in vitro using U251 cells as a model

scientific article published on 29 September 2016

CAR T-cells for cancer therapy

scientific article published on 12 February 2018

Clinical attributes and surgical outcomes of angiocentric gliomas

scientific article

Cognitive trajectories and spectrum of neuropathology in SuperAgers: The first ten cases

scientific article published on 17 January 2018

Combined Pathologies in FTLD-TDP Types A and C.

scientific article published on 23 March 2018

Defining the pathway for Tat-mediated delivery of beta-glucuronidase in cultured cells and MPS VII mice.

scientific article published on August 2005

Delayed malignant transformation of petroclival meningioma to chondrosarcoma after stereotactic radiosurgery.

scientific article published on 13 December 2013

Detection of CD133 expression in U87 glioblastoma cells using a novel anti-CD133 monoclonal antibody

scientific article

Development of a Sensitive Luciferase-Based Sandwich ELISA System for the Detection of Human Extracellular Matrix 1 Protein.

scientific article published on 6 December 2016

Domain-Specific Monoclonal Antibodies Against Human Rev-erbβ.

scientific article published on 16 December 2016

Domain-specific monoclonal antibodies produced against human PGRN.

scientific article published on June 2011

Erratum to: Predictors of recurrence in the management of chordoid meningioma

scientific article published on 01 January 2016

Establishing a dual knock-out cell line by lentivirus based combined CRISPR/Cas9 and Loxp/Cre system

scientific article published on 01 September 2018

Establishment of a DGKθ Endogenous Promoter Luciferase Reporter HepG2 Cell Line for Studying the Transcriptional Regulation of DGKθ Gene

scientific article published on 19 September 2018

Establishment of a HEK293 cell line by CRISPR/Cas9-mediated luciferase knock-in to study transcriptional regulation of the human SREBP1 gene

scientific article published on 19 September 2018

Establishment of a cell line carrying single copy of an exogenous mutant reporter gene for assaying the biological activity of ZFNs.

scientific article

Establishment of a novel hepatic steatosis cell model by Cas9/sgRNA-mediated DGKθ gene knockout

scientific article published on 22 November 2017

FTLD-TDP With and Without GRN Mutations Cause Different Patterns of CA1 Pathology

scientific article published on 01 September 2019

Generation of Domain-Specific Monoclonal Antibodies Against Human Glutaredoxin3.

scientific article published on 6 December 2016

Generation of a novel HEK293 luciferase reporter cell line by CRISPR/Cas9-mediated site-specific integration in the genome to explore the transcriptional regulation of the PGRN gene

scientific article published on 01 December 2019

Generation of apoptosis-resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production.

scientific article

Genetically modified adenoviral vector with the protein transduction domain of Tat improves gene transfer to CAR-deficient cells

scientific article

Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

scientific article published on 15 February 2021

Inclusions in frontotemporal lobar degeneration with TDP-43 proteinopathy (FTLD-TDP) and amyotrophic lateral sclerosis (ALS), but not FTLD with FUS proteinopathy (FTLD-FUS), have properties of amyloid.

scientific article published on 3 February 2013

Intracellular trafficking of CLN3, the protein underlying the childhood neurodegenerative disease, Batten disease.

scientific article published on December 2003

Intracranial delivery of CLN2 reduces brain pathology in a mouse model of classical late infantile neuronal ceroid lipofuscinosis.

scientific article

MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology

scientific article published on 30 October 2019

Membrane topology of CLN3, the protein underlying Batten disease

scientific article

Multiple copies of a linear donor fragment released in situ from a vector improve the efficiency of zinc-finger nuclease-mediated genome editing.

scientific article published on 16 January 2014

Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG).

scientific article published on 7 June 2017

Neuroendocrine carcinoma of the pineal parenchyma. The first reported case

scientific article published on 11 October 2016

Orbital metastasis of pituitary growth hormone secreting carcinoma causing lateral gaze palsy ⬇️

scientific article published on April 18, 2013

Pineal chordoid meningioma complicated by repetitive hemorrhage during pregnancy: case report and literature review.

scientific article

Predictors of recurrence in the management of chordoid meningioma

scientific article

Production and Characterization of Monoclonal Antibodies against Human Nuclear Protein FAM76B.

scientific article

Production and characterization of domain-specific monoclonal antibodies against human ECM1.

scientific article published on 27 January 2016

Prognostic factors for recurrence and complications in the surgical management of primary chordoid gliomas: A systematic review of literature

scientific article

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model

scientific article

RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.

scientific article published on 4 July 2004

Rescue the Failed Half-ZFN by a Sensitive Mammalian Cell-Based Luciferase Reporter System ⬇️

scientific article published on September 18, 2012

Revisiting the utility of TDP-43 immunoreactive (TDP-43-ir) pathology to classify FTLD-TDP subtypes

scientific article published on 07 May 2019

Sleep talking and primary progressive aphasia: case study and autopsy findings in a patient with logopenic primary progressive aphasia and dementia with Lewy bodies

scientific article published on 27 May 2019

Somatostatin Receptor Ligand Therapy-A Potential Therapy for Neurocytoma

scientific article published on 01 June 2019

Suppression of Progranulin Expression Leads to Formation of Intranuclear TDP-43 Inclusions In Vitro: A Cell Model of Frontotemporal Lobar Degeneration

scientific article published on 01 December 2019

Targeted genome correction by a single adenoviral vector simultaneously carrying an inducible zinc finger nuclease and a donor template.

scientific article published on 10 August 2014

The HIV Tat protein transduction domain improves the biodistribution of beta-glucuronidase expressed from recombinant viral vectors.

scientific article published on July 2001

The Role of Macrophages in the Response to TNF Inhibition in Experimental Arthritis

scientific article published on 17 November 2017

siRNA-mediated gene silencing in vitro and in vivo.

scientific article

List of works by Qinwen Mao

A Fiber Chimeric CRAd Vector Ad5/11-D24 Double-Armed with TRAIL and Arresten for Enhanced Glioblastoma Therapy ⬇️

A Highly Sensitive Sandwich ELISA to Detect CSF Progranulin: A Potential Biomarker for CNS Disorders

A dorsally located giant posterior fossa neurenteric cyst in a Chinese woman

A knock-in reporter model of Batten disease

A mouse model of classical late-infantile neuronal ceroid lipofuscinosis based on targeted disruption of the CLN2 gene results in a loss of tripeptidyl-peptidase I activity and progressive neurodegeneration

A novel Ad5/11 chimeric oncolytic adenovirus for improved glioma therapy.

A novel adenoviral vector carrying an all-in-one Tet-On system with an autoregulatory loop for tight, inducible transgene expression.

A novel conditionally replicating adenoviral vector with dual expression of IL-24 and arresten inserted in E1 and the region between E4 and fiber for improved melanoma therapy.

A novel luciferase knock-in reporter system for studying transcriptional regulation of the human Sox2 gene.

A novel system for rapid screening of effective siRNA target sites by one step transfection with a single vector.

A novel vector for a rapid generation of fiber-mutant adenovirus based on one step ligation and quick screening of positive clones ⬇️

A one-step ligation system for rapid generation of armed, conditionally-replicating adenoviruses ⬇️

A rapid generation of adenovirus vector with a genetic modification in hexon protein

A simple, efficient and economical method for isolating and culturing human umbilical cord blood‑derived mesenchymal stromal cells

A targeting peptide improves adenovirus-mediated transduction of a glioblastoma cell line

Accreditation Council for Graduate Medical Education Self-Study for Pathology: One Institution's Experience and Lessons Learned

Adult polyglucosan body disease with GBE1 haploinsufficiency and concomitant frontotemporal lobar degeneration

Aptamer modification improves the adenoviral transduction of malignant glioma cells.

Aptazyme-mediated direct modulation of post-transcriptional sgRNA level for conditional genome editing and gene expression

Biological function analysis of monoclonal antibodies against human granulins in vitro using U251 cells as a model

CAR T-cells for cancer therapy

Clinical attributes and surgical outcomes of angiocentric gliomas

Cognitive trajectories and spectrum of neuropathology in SuperAgers: The first ten cases

Combined Pathologies in FTLD-TDP Types A and C.

Defining the pathway for Tat-mediated delivery of beta-glucuronidase in cultured cells and MPS VII mice.

Delayed malignant transformation of petroclival meningioma to chondrosarcoma after stereotactic radiosurgery.

Detection of CD133 expression in U87 glioblastoma cells using a novel anti-CD133 monoclonal antibody

Development of a Sensitive Luciferase-Based Sandwich ELISA System for the Detection of Human Extracellular Matrix 1 Protein.

Domain-Specific Monoclonal Antibodies Against Human Rev-erbβ.

Domain-specific monoclonal antibodies produced against human PGRN.

Erratum to: Predictors of recurrence in the management of chordoid meningioma

Establishing a dual knock-out cell line by lentivirus based combined CRISPR/Cas9 and Loxp/Cre system

Establishment of a DGKθ Endogenous Promoter Luciferase Reporter HepG2 Cell Line for Studying the Transcriptional Regulation of DGKθ Gene

Establishment of a HEK293 cell line by CRISPR/Cas9-mediated luciferase knock-in to study transcriptional regulation of the human SREBP1 gene

Establishment of a cell line carrying single copy of an exogenous mutant reporter gene for assaying the biological activity of ZFNs.

Establishment of a novel hepatic steatosis cell model by Cas9/sgRNA-mediated DGKθ gene knockout

FTLD-TDP With and Without GRN Mutations Cause Different Patterns of CA1 Pathology

Generation of Domain-Specific Monoclonal Antibodies Against Human Glutaredoxin3.

Generation of a novel HEK293 luciferase reporter cell line by CRISPR/Cas9-mediated site-specific integration in the genome to explore the transcriptional regulation of the PGRN gene

Generation of apoptosis-resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production.

Genetically modified adenoviral vector with the protein transduction domain of Tat improves gene transfer to CAR-deficient cells

Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

Inclusions in frontotemporal lobar degeneration with TDP-43 proteinopathy (FTLD-TDP) and amyotrophic lateral sclerosis (ALS), but not FTLD with FUS proteinopathy (FTLD-FUS), have properties of amyloid.

Intracellular trafficking of CLN3, the protein underlying the childhood neurodegenerative disease, Batten disease.

Intracranial delivery of CLN2 reduces brain pathology in a mouse model of classical late infantile neuronal ceroid lipofuscinosis.

MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology

Membrane topology of CLN3, the protein underlying Batten disease

Multiple copies of a linear donor fragment released in situ from a vector improve the efficiency of zinc-finger nuclease-mediated genome editing.

Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG).

Neuroendocrine carcinoma of the pineal parenchyma. The first reported case

Orbital metastasis of pituitary growth hormone secreting carcinoma causing lateral gaze palsy ⬇️

Pineal chordoid meningioma complicated by repetitive hemorrhage during pregnancy: case report and literature review.

Predictors of recurrence in the management of chordoid meningioma

Production and Characterization of Monoclonal Antibodies against Human Nuclear Protein FAM76B.

Production and characterization of domain-specific monoclonal antibodies against human ECM1.

Prognostic factors for recurrence and complications in the surgical management of primary chordoid gliomas: A systematic review of literature

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model

RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.

Rescue the Failed Half-ZFN by a Sensitive Mammalian Cell-Based Luciferase Reporter System ⬇️

Revisiting the utility of TDP-43 immunoreactive (TDP-43-ir) pathology to classify FTLD-TDP subtypes

Sleep talking and primary progressive aphasia: case study and autopsy findings in a patient with logopenic primary progressive aphasia and dementia with Lewy bodies

Somatostatin Receptor Ligand Therapy-A Potential Therapy for Neurocytoma

Suppression of Progranulin Expression Leads to Formation of Intranuclear TDP-43 Inclusions In Vitro: A Cell Model of Frontotemporal Lobar Degeneration

Targeted genome correction by a single adenoviral vector simultaneously carrying an inducible zinc finger nuclease and a donor template.

The HIV Tat protein transduction domain improves the biodistribution of beta-glucuronidase expressed from recombinant viral vectors.

The Role of Macrophages in the Response to TNF Inhibition in Experimental Arthritis

siRNA-mediated gene silencing in vitro and in vivo.