List of works - Oleg Tolmachov

A heterologous system for assembly of retroviral gene vectors: intracellular budding in yeast?

scientific article published on 8 June 2006

Accurate size gauging of ExoIII/S1-generated deletions by PCR analysis of ligation mixtures

scientific article published in April 2005

An araC-controlled bacterial cre expression system to produce DNA minicircle vectors for nuclear and mitochondrial gene therapy.

scientific article published on 13 April 2001

Building mosaics of therapeutic plasmid gene vectors.

scientific article published on December 2011

CHM/REP1 cDNA delivery by lentiviral vectors provides functional expression of the transgene in the retinal pigment epithelium of choroideremia mice

scientific article published on 01 March 2012

Coupled analysis of bacterial transformants and ligation mixture by duplex PCR enables detection of fatal instability of a nascent recombinant plasmid.

scientific article

Covalent attachment of multifunctional chimeric terminal proteins to 5' DNA ends: A potential new strategy for assembly of synthetic therapeutic gene vectors.

scientific article

Designing plasmid vectors.

scientific article published on January 2009

Development of a self-assembling nuclear targeting vector system based on the tetracycline repressor protein.

scientific article published on 7 November 2003

Functional expression of Rab escort protein 1 following AAV2-mediated gene delivery in the retina of choroideremia mice and human cells ex vivo

scientific article published on 12 June 2013

Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells

scientific article

Nuclear-targeted minicircle to enhance gene transfer with non-viral vectors in vitro and in vivo.

scientific article published on June 2006

Overexpression of connexin 43 using a retroviral vector improves electrical coupling of skeletal myoblasts with cardiac myocytes in vitro

scientific article published on 6 June 2006

RecET driven chromosomal gene targeting to generate a RecA deficient Escherichia coli strain for Cre mediated production of minicircle DNA.

scientific article

Remarkable stability of an instability-prone lentiviral vector plasmid in Escherichia coli Stbl3.

scientific article published on 27 July 2012

Self-entanglement of long linear DNA vectors using transient non-B-DNA attachment points: A new concept for improvement of non-viral therapeutic gene delivery ⬇️

scientific article published on February 20, 2012

Self-focusing therapeutic gene delivery with intelligent gene vector swarms: intra-swarm signalling through receptor transgene expression in targeted cells

scientific article published on 17 December 2014

Shielding of non-target cells using RNA vectors conferring gene transfer resistance: A strategy to enhance targeting accuracy and reduce side-effects in therapeutic gene delivery

scientific article published on 25 July 2019

Split vector systems for ultra-targeted gene delivery: a contrivance to achieve ethical assurance of somatic gene therapy in vivo

scientific article published on 2 May 2014

Tightly-wound miniknot vectors for gene therapy: a potential improvement over supercoiled minicircle DNA.

scientific article published on 13 November 2009

Transgenic DNA modules with pre-programmed self-destruction: Universal molecular devices to escape 'genetic litter' in gene and cell therapy.

scientific article

List of works by Oleg Tolmachov

A heterologous system for assembly of retroviral gene vectors: intracellular budding in yeast?

Accurate size gauging of ExoIII/S1-generated deletions by PCR analysis of ligation mixtures

An araC-controlled bacterial cre expression system to produce DNA minicircle vectors for nuclear and mitochondrial gene therapy.

Building mosaics of therapeutic plasmid gene vectors.

CHM/REP1 cDNA delivery by lentiviral vectors provides functional expression of the transgene in the retinal pigment epithelium of choroideremia mice

Coupled analysis of bacterial transformants and ligation mixture by duplex PCR enables detection of fatal instability of a nascent recombinant plasmid.

Covalent attachment of multifunctional chimeric terminal proteins to 5' DNA ends: A potential new strategy for assembly of synthetic therapeutic gene vectors.

Designing plasmid vectors.

Development of a self-assembling nuclear targeting vector system based on the tetracycline repressor protein.

Functional expression of Rab escort protein 1 following AAV2-mediated gene delivery in the retina of choroideremia mice and human cells ex vivo

Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells

Nuclear-targeted minicircle to enhance gene transfer with non-viral vectors in vitro and in vivo.

Overexpression of connexin 43 using a retroviral vector improves electrical coupling of skeletal myoblasts with cardiac myocytes in vitro

RecET driven chromosomal gene targeting to generate a RecA deficient Escherichia coli strain for Cre mediated production of minicircle DNA.

Remarkable stability of an instability-prone lentiviral vector plasmid in Escherichia coli Stbl3.

Self-entanglement of long linear DNA vectors using transient non-B-DNA attachment points: A new concept for improvement of non-viral therapeutic gene delivery ⬇️

Self-focusing therapeutic gene delivery with intelligent gene vector swarms: intra-swarm signalling through receptor transgene expression in targeted cells

Shielding of non-target cells using RNA vectors conferring gene transfer resistance: A strategy to enhance targeting accuracy and reduce side-effects in therapeutic gene delivery

Split vector systems for ultra-targeted gene delivery: a contrivance to achieve ethical assurance of somatic gene therapy in vivo

Tightly-wound miniknot vectors for gene therapy: a potential improvement over supercoiled minicircle DNA.

Transgenic DNA modules with pre-programmed self-destruction: Universal molecular devices to escape 'genetic litter' in gene and cell therapy.