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List of works by Hatem Zayed

A Potential Link Between Oxidative Stress and Endothelial-to-Mesenchymal Transition in Systemic Sclerosis

scientific article published on 19 September 2018

A comparative computational approach toward pharmacological chaperones (NN-DNJ and ambroxol) on N370S and L444P mutations causing Gaucher's disease

scientific article published on 01 December 2018

A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation causing breast cancer

scientific article published on 21 October 2019

A computational method to characterize the missense mutations in the catalytic domain of GAA protein causing Pompe disease

scholarly article by D Thirumal Kumar published in October 2018

A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase

scientific article published on 07 January 2019

A maternally inherited chromosome 18q22.1 deletion in a male with late-presenting diaphragmatic hernia and microphthalmia-evaluation of DSEL as a candidate gene for the diaphragmatic defect

scientific article published in April 2010

A profound computational study to prioritize the disease-causing mutations in PRPS1 gene

scientific article

Accredited genetic testing in the Arab Gulf region: reinventing the wheel

An Arab Registry for Type 1 Diabetes: Global Benefits for Type 1 Diabetes Patients

scientific article published on 5 June 2016

An extensive computational approach to analyze and characterize the functional mutations in the galactose-1-phosphate uridyl transferase (GALT) protein responsible for classical galactosemia

scientific article published on 13 December 2019

An integrative bioinformatics pipeline to demonstrate the alteration of the interaction between the ALDH2*2 allele with NAD+ and Disulfiram

scientific article published on 19 May 2019

Anaphylaxis triggers in a large tertiary care hospital in Qatar: a retrospective study

scientific article published on 04 September 2018

Association between Soft Drink Consumption and Aggressive Behaviour among a Quarter Million Adolescents from 64 Countries Based on the Global School-Based Student Health Survey (GSHS)

scientific article published on 05 March 2020

Association of Genetic Variants with Colorectal Cancer in the Extended MENA Region: A Systematic Review

scientific article published on 01 January 2020

Bioinformatics classification of mutations in patients with Mucopolysaccharidosis IIIA

scientific article published on 05 August 2019

Breast cancer in the GCC countries: A focus on BRCA1/2 and non-BRCA1/2 genes

CD146, a novel target of CD44-signaling, suppresses breast tumor cell invasion

scientific article

CD44 mediates stem cell mobilization to damaged lung via its novel transcriptional targets, Cortactin and Survivin

scientific article published on 01 January 2020

Canavan disease: an Arab scenario

scientific article

Clinical Exome Sequencing unravels new disease-causing mutations in the myeloproliferative neoplasms: A pilot study in patients from the state of Qatar

scientific article published on 13 December 2018

Clinical, biochemical, neuroradiological and molecular characterization of Egyptian patients with glutaric acidemia type 1

scientific article published on 06 May 2019

Comparative computational assessment of the pathogenicity of mutations in the Aspartoacylase enzyme

scientific article

Comprehensive in silico screening and molecular dynamics studies of missense mutations in Sjogren-Larsson syndrome associated with the ALDH3A2 gene

scientific article published on 04 February 2020

Computational and modeling approaches to understand the impact of the Fabry's disease causing mutation (D92Y) on the interaction with pharmacological chaperone 1-deoxygalactonojirimycin (DGJ)

scientific article published on 18 December 2018

Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2

Computational insights of K1444N substitution in GAP-related domain of NF1 gene associated with neurofibromatosis type 1 disease: a molecular modeling and dynamics approach

article

Computational model to analyze and characterize the functional mutations of NOD2 protein causing inflammatory disorder - Blau syndrome

scientific article published on 04 February 2020

Computational modelling approaches as a potential platform to understand the molecular genetics association between Parkinson’s and Gaucher diseases

article

Congenital diaphragmatic hernia and microtia in a newborn with mycophenolate mofetil (MMF) exposure: phenocopy for Fryns syndrome or broad spectrum of teratogenic effects?

Correction of DNA protein kinase deficiency by spliceosome-mediated RNA trans-splicing and sleeping beauty transposon delivery

scientific article published on 24 April 2007

Corrigendum: Genetic Epidemiology of Glucose-6-Phosphate Dehydrogenase Deficiency in the Arab World

scientific article published on 3 January 2017

Deciphering the Role of Filamin B Calponin-Homology Domain in Causing the Larsen Syndrome, Boomerang Dysplasia, and Atelosteogenesis Type I Spectrum Disorders via a Computational Approach

scientific article published on 26 November 2020

Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach

scientific article

Development of hyperactive sleeping beauty transposon vectors by mutational analysis

scientific article

Differences in the neovascular potential of thymus versus subcutaneous adipose-derived stem cells from patients with myocardial ischaemia.

scientific article

Durable immunity to oncogenic human papillomaviruses elicited by adjuvanted recombinant Adeno-associated virus-like particle immunogen displaying L2 17-36 epitopes

scientific article

Elucidating the role of interacting residues of the MSH2-MSH6 complex in DNA repair mechanism: A computational approach

scientific article published on 07 January 2019

Enhanced Identification of Transcriptional Enhancers Provides Mechanistic Insights into Diseases

scientific article

Epidemiology of diabetic ketoacidosis in Arab patients with type 1 diabetes: a systematic review

scientific article published on 4 February 2016

Genetic Epidemiology of Glucose-6-Dehydrogenase Deficiency in the Arab World

scientific article

Genetic Epidemiology of Hearing Loss in the 22 Arab Countries: A Systematic Review

scientific article published on 01 February 2020

Genetic Epidemiology of Type 1 Diabetes in the 22 Arab Countries

scientific article published on May 2016

Genetic epidemiology of beta-thalassemia in the Maldives: 23 years of a beta-thalassemia screening program

scientific article published on 09 March 2020

Genetic epidemiology of ovarian cancer in the 22 Arab countries: A systematic review

article

Genetic polymorphisms associated with type 2 diabetes in the Arab world: A systematic review and meta-analysis

scientific article published on 04 April 2019

Genotype-phenotype correlation in 18 Egyptian patients with glutaric acidemia type I.

scientific article published on 07 April 2017

Genotype-phenotype correlation in patients with isovaleric acidaemia: comparative structural modelling and computational analysis of novel variants

scientific article published on 23 May 2017

Identification of potential inhibitors against pathogenic missense mutations of PMM2 using a structure-based virtual screening approach

scientific article published on 06 January 2020

Immunogenetics of Celiac Disease: A Focus on Arab Countries

scientific article published on 01 January 2020

Impact of missense mutations in survival motor neuron protein (SMN1) leading to Spinal Muscular Atrophy (SMA): A computational approach

Implication of salt stress induces changes in pigment production, antioxidant enzyme activity, and qRT-PCR expression of genes involved in the biosynthetic pathway of Bixa orellana L

scientific article published on 29 January 2019

In silico and in vivo models for Qatari-Specific classical homocystinuria as basis for development of novel therapies

article

In vitro functional correction of the mutation responsible for murine severe combined immune deficiency by small fragment homologous replacement.

scientific article

Inositol 1,4,5-Trisphosphate Receptors in Hypertension

scientific article published on 26 July 2018

Integrative Bioinformatics Approaches to Map Potential Novel Genes and Pathways Involved in Ovarian Cancer

scientific article published on 17 December 2019

Investigating the structural impacts of a novel missense variant identified with whole exome sequencing in an Egyptian patient with propionic acidemia

scientific article published on 17 September 2020

Involvement of Essential Signaling Cascades and Analysis of Gene Networks in Diabesity

scientific article published on 25 October 2020

Krabbe Disease in the Arab World

scientific article published on March 2015

Molecular dynamics simulations to decipher the structural and functional consequences of pathogenic missense mutations in the galactosylceramidase (GALC) protein causing Krabbe's disease

scientific article published on 31 March 2020

Molecular dynamics-based analyses of the structural instability and secondary structure of the fibrinogen gamma chain protein with the D356V mutation

scientific article

Molecular insights of the G2019S substitution in LRRK2 kinase domain associated with Parkinson's disease: A molecular dynamics simulation approach

scientific article published on 04 March 2019

Myocardial Ischemic Subject's Thymus Fat: A Novel Source of Multipotent Stromal Cells

scientific article published on 10 December 2015

Neuropathy of type 1 diabetes in the Arab world: A systematic review and meta-analysis

scientific article published on 22 March 2017

Novel CD44-downstream signaling pathways mediating breast tumor invasion

scholarly article by Allal Ouhtit published in October 2018

Novel Comprehensive Bioinformatics Approaches to Determine the Molecular Genetic Susceptibility Profile of Moderate and Severe Asthma

scientific article published on 04 June 2020

Novel mutation in an Egyptian patient with infantile Canavan disease

scientific article published on 28 November 2015

Potential routes of spread of Zika virus to the Middle East, North Africa and Asia: action must be taken

article

Prevalence of nephropathy in type 1 diabetes in the Arab world: A systematic review and meta-analysis

scientific article published on 08 June 2018

Propionic acidemia in the Arab World

scientific article published on 09 April 2015

Protective Effect of Cyclically Pressurized Solid–Liquid Extraction Polyphenols from Cagnulari Grape Pomace on Oxidative Endothelial Cell Death

scientific article published on 21 August 2018

RPL13A and EEF1A1 Are Suitable Reference Genes for qPCR during Adipocyte Differentiation of Vascular Stromal Cells from Patients with Different BMI and HOMA-IR.

scientific article

Rapid generation of stable cell lines expressing high levels of erythropoietin, factor VIII, and an antihuman CD20 antibody using lentiviral vectors

scientific article published on August 2013

Retinopathy of Type 1 Diabetes in Arab Countries: Systematic Review and Meta-Analysis

scientific article published on 25 July 2018

Reverse Zoonotic Transmission of SARS-CoV-2 and Monkeypox Virus: A Comprehensive Review

scientific article published in May 2024

Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance

scientific article published on 12 March 2020

Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling

scientific article published on 17 April 2019

Sanguinarine Induces Apoptosis in Papillary Thyroid Cancer Cells via Generation of Reactive Oxygen Species

scientific article published on 09 March 2020

Severe neurological manifestations in an Egyptian patient with a novel frameshift mutation in the Glutaryl-CoA dehydrogenase gene

scientific article published in August 2016

Spectrum of mutations of cystic fibrosis in the 22 Arab countries: A systematic review

scientific article published on 12 November 2018

Spectrum of mutations of familial hypercholesterolemia in the 22 Arab countries

article published in 2018

Structural Analysis of G1691S Variant in the Human Filamin B Gene Responsible for Larsen Syndrome: A Comparative Computational Approach.

scientific article

Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope

scientific article published in December 2017

Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2

scientific article published on 12 June 2018

Structural modeling of p.V31F variant in the aspartoacylase gene

scientific article published on 21 January 2016

Substitution impact of highly conserved arginine residue at position 75 in GJB1 gene in association with X-linked Charcot-Marie-tooth disease: A computational study

scientific article published on 27 October 2017

The Arab genome: Health and wealth

scientific article

The DNA-bending protein HMGB1 is a cellular cofactor of Sleeping Beauty transposition

scientific article

The Qatar genome project: translation of whole-genome sequencing into clinical practice

scientific article

The Role of Extracellular Vesicles as Modulators of the Tumor Microenvironment, Metastasis and Drug Resistance in Colorectal Cancer

scientific article published on 29 May 2019

The transcriptomic profiling of COVID-19 compared to SARS, MERS, Ebola, and H1N1

scientific article published on 09 May 2020

The transcriptomic profiling of SARS-CoV-2 compared to SARS, MERS, EBOV, and H1N1

scientific article published on 10 December 2020

Two patients with Canavan disease and structural modeling of a novel mutation

scientific article

Understanding Gene Expression and Transcriptome Profiling of COVID-19: An Initiative Towards the Mapping of Protective Immunity Genes Against SARS-CoV-2 Infection

scientific article published on 15 December 2021

Understanding the structure-function relationship of HPRT1 missense mutations in association with Lesch-Nyhan disease and HPRT1-related gout by in silico mutational analysis

scientific article published on 23 February 2019

Whole-Genome Sequencing of 100 Genomes Identifies a Distinctive Genetic Susceptibility Profile of Qatari Patients with Hypertension

scientific article published on 29 April 2022

miR-20b, miR-296, and Let-7f Expression in Human Adipose Tissue is Related to Obesity and Type 2 Diabetes

scientific article published on 30 December 2018

miR-21 mimic blocks obesity in mice: A novel therapeutic option

scientific article published on 02 July 2021

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