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List of works by Jan O Friedrich

"Stop right there...I gotta know right now!" Do steroids really help for CAP?

scientific article published in September 2005

31P nuclear magnetic resonance spectroscopic imaging of regions of remodeled myocardium in the infarcted rat heart

scientific article published on 01 December 1995

A study protocol for an observational cohort investigating COGnitive outcomes and WELLness in survivors of critical illness: the COGWELL study

scientific article

Automated weaning and SBT systems versus non-automated weaning strategies for weaning time in invasively ventilated critically ill adults

scientific article published on 9 September 2014

Automated weaning and spontaneous breathing trial systems versus non-automated weaning strategies for discontinuation time in invasively ventilated postoperative adults

scientific article

Benefits and risks associated with thrombolysis for pulmonary embolism

scientific article published on 01 October 2014

Characteristics, clinical course, and outcomes of homeless and non-homeless patients admitted to ICU: A retrospective cohort study.

scientific article

Clinical practice guideline: management of acute pancreatitis

scientific article

Coenrollment in a randomized trial of high-frequency oscillation: prevalence, patterns, predictors, and outcomes*.

scientific article published on February 2015

Colchicine in cardiac disease: a systematic review and meta-analysis of randomized controlled trials

scientific article (publication date: 2015)

Comparison of coronary artery bypass surgery and percutaneous coronary intervention in patients with diabetes: a meta-analysis of randomised controlled trials

scientific article published on 13 September 2013

Comparison of standard and accelerated initiation of renal replacement therapy in acute kidney injury.

scientific article published on 8 July 2015

Compliance with Evidence-Based Guidelines in Acute Pancreatitis: an Audit of Practices in University of Toronto Hospitals.

scientific article

Coronary Artery Bypass Graft Should Be Considered in Octogenarians With Multivessel Coronary Disease

scientific article published on 04 February 2016

Creatine kinase system in failing and nonfailing human myocardium

scientific article published on 01 October 1996

Critical illness in homeless persons is poorly studied: a systematic review of the literature.

scientific article

Decontamination of the digestive tract in ICU patients

scientific article published on 01 May 2009

Dipeptidyl peptidase-4 inhibitors and the risk of heart failure: a systematic review and meta-analysis

scientific article

Discordance between perception and treatment practices associated with intensive care unit-acquired bacteriuria and funguria: a Canadian physician survey

scientific article published on 01 April 2008

Do we need a pharmacist in the ICU?

scientific article published on 21 May 2015

Does intensive insulin therapy really reduce mortality in critically ill surgical patients? A reanalysis of meta-analytic data.

scientific article

Drotrecogin Alfa (Activated) in Severe Sepsis

scientific article published on 01 January 2006

Drotrecogin alfa (activated) in patients with severe sepsis and a high risk of death.

scientific article published on January 2006

Drotrecogin alfa (activated): down and not out, but not really in either.

scientific article published on January 2006

Effect of High-Flow Nasal Cannula Oxygen Therapy Versus Conventional Oxygen Therapy and Noninvasive Ventilation on Reintubation Rate in Adult Patients After Extubation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

scientific article published on January 2017

Effect of mechanical ventilation in the prone position on clinical outcomes in patients with acute hypoxemic respiratory failure: a systematic review and meta-analysis.

scientific article published on April 2008

Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and meta-analysis.

scientific article

Effect of prone positioning during mechanical ventilation on mortality among patients with acute respiratory distress syndrome: a systematic review and meta-analysis

scientific article

Effect of prone positioning in patients with acute respiratory distress syndrome and high Simplified Acute Physiology Score II.

scientific article

Effort to Breathe with Various Spontaneous Breathing Trial Techniques. A Physiologic Meta-analysis.

scientific article

Enalapril treatment increases cardiac performance and energy reserve via the creatine kinase reaction in myocardium of Syrian myopathic hamsters with advanced heart failure

scientific article published in March 1995

Epidemiology of acute kidney injury in Canadian critical care units: a prospective cohort study.

scientific article published on 28 July 2012

Erratum to: Risk factors for mortality in patients admitted to intensive care units with pneumonia

scientific article published on 7 October 2016

Evaluation of Metabolic and Synaptic Dysfunction Hypotheses of Alzheimer's Disease (AD): A Meta-Analysis of CSF Markers

scientific article published on 21 September 2017

Failure of anticoagulant thromboprophylaxis: risk factors in medical-surgical critically ill patients*.

scientific article published on February 2015

Has mortality from acute respiratory distress syndrome decreased over time?: A systematic review.

scientific article

Hemofiltration compared to hemodialysis for acute kidney injury: systematic review and meta-analysis.

scientific article published on 06 August 2012

Heparin-induced thrombocytopenia in the critically ill: interpreting the 4Ts test in a randomized trial

scientific article

High-dose renal replacement therapy for acute kidney injury: Systematic review and meta-analysis

scientific article published on May 2010

High-dose renal replacement therapy for acute kidney injury: Systematic review and meta-analysis--addendum

scientific article published on 01 December 2010

High-frequency oscillation in adults: A utilization review* ⬇️

scientific article published on December 1, 2011

High-frequency oscillatory ventilation versus conventional ventilation for acute respiratory distress syndrome

scientific article published on 4 April 2016

High-frequency ventilation versus conventional ventilation for treatment of acute lung injury and acute respiratory distress syndrome

scientific article

Improving patient care through the use of evidence based order sets

scientific article published on January 2005

Inclusion of zero total event trials in meta-analyses maintains analytic consistency and incorporates all available data

scientific article

Inhaled nitric oxide does not reduce mortality in patients with acute respiratory distress syndrome regardless of severity: systematic review and meta-analysis.

scientific article

Inter-hospital transfers and outcomes of critically ill patients with severe acute kidney injury: a multicenter cohort study.

scientific article

Is nosocomial infection really the major cause of death in sepsis?

scientific article published on October 2014

Long-term outcomes and clinical predictors of hospital mortality in very long stay intensive care unit patients: a cohort study.

scientific article

Low-molecular-weight heparin venous thromboprophylaxis in critically ill patients with renal dysfunction: A subgroup analysis of the PROTECT trial.

scientific article published in June 2018

Management of Acute Respiratory Distress Syndrome and Refractory Hypoxemia. A Multicenter Observational Study

scientific article published on 14 September 2017

Medical admission order sets: effective, practical, generalizable--but not perfect

scientific article published on 01 September 2009

Meta-analysis: low-dose dopamine increases urine output but does not prevent renal dysfunction or death.

scientific article

Nurse- vs nomogram-directed glucose control in a cardiovascular intensive care unit.

scientific article published on July 2012

One-Year Outcomes in Caregivers of Critically Ill Patients

scientific article

Optimal dose of renal replacement therapy in acute kidney injury: a meta-analysis.

scientific article published on 13 March 2009

Optimal dosing of antibiotics in critically ill patients by using continuous/extended infusions: a systematic review and meta-analysis

scientific article

Optimizing the approach to pain, agitation, and delirium in critical care

scientific article published on 06 May 2014

Patient safety, resident well-being and continuity of care with different resident duty schedules in the intensive care unit: a randomized trial.

scientific article

Patients' preferences for enrolment into critical-care trials

scientific article published on 24 June 2009

Phosphocreatine T1 measurements with and without exchange in the heart

scientific article published on 01 July 1993

Post Arrest Consult Team: a knowledge translation strategy for post-cardiac arrest care.

scientific article published on 17 March 2014

Pressure-Controlled vs Volume-Controlled Ventilation in Acute Respiratory Failure: A Physiology-Based Narrative and Systematic Review.

scientific article published on August 2015

Previous cultures are not clinically useful for guiding empiric antibiotics in suspected ventilator-associated pneumonia: secondary analysis from a randomized trial

scientific article published in March 2008

Prolonged time to alarm in infusion devices operated at low flow rates

scientific article published in October 2008

Prone position ventilation for community-acquired pneumonia

scientific article published on 01 February 2008

Prone ventilation reduces mortality in patients with acute respiratory failure and severe hypoxemia: systematic review and meta-analysis

scientific article published on 04 February 2010

Ratio of geometric means to analyze continuous outcomes in meta-analysis: comparison to mean differences and ratio of arithmetic means using empiric data and simulation

scientific article

Ratio of means for analyzing continuous outcomes in meta-analysis performed as well as mean difference methods ⬇️

scientific article published on May 1, 2011

Recombinant activated factor VII for acute intracerebral hemorrhage

scientific article published on 01 May 2005

Relationship of catheter-associated urinary tract infection to mortality and length of stay in critically ill patients: a systematic review and meta-analysis of observational studies.

scientific article published on May 2011

Risk of chronic dialysis and death following acute kidney injury

scientific article published on 18 April 2012

Rosiglitazone: can meta-analysis accurately estimate excess cardiovascular risk given the available data? Re-analysis of randomized trials using various methodologic approaches

scientific article

Should dual antiplatelet therapy be used in patients following coronary artery bypass surgery? A meta-analysis of randomized controlled trials

scientific article

Surrogate decision makers' attitudes towards research decision making for critically ill patients

scientific article published on 24 July 2012

Systematic review and meta-analysis of chordal replacement versus leaflet resection for posterior mitral leaflet prolapse

scientific article published on 24 August 2017

The Association Between Renal Replacement Therapy Modality and Long-Term Outcomes Among Critically Ill Adults With Acute Kidney Injury

scientific article published on 01 April 2014

The Postcardiac Arrest Consult Team: Impact on Hospital Care Processes for Out-of-Hospital Cardiac Arrest Patients.

scientific article

The RECOVER Program: Disability Risk Groups & One Year Outcome after ≥ 7 Days of Mechanical Ventilation.

scientific article published on 14 March 2016

The authors reply

The hemodynamic tolerability and feasibility of sustained low efficiency dialysis in the management of critically ill patients with acute kidney injury.

scientific article

The ratio of means method as an alternative to mean differences for analyzing continuous outcome variables in meta-analysis: a simulation study

scientific article

The use of wireless e-mail to improve healthcare team communication.

scientific article published on 30 June 2009

Thrombocytopenia in critically ill patients receiving thromboprophylaxis: frequency, risk factors, and outcomes

scientific article

Timing the initiation of renal replacement therapy for acute kidney injury in Canadian intensive care units: a multicentre observational study.

scientific article published on 30 June 2012

Transcatheter vs Surgical Aortic Valve Replacement for Aortic Stenosis in Low-Intermediate Risk Patients: A Meta-analysis.

scientific article published on 15 June 2017

Transfusion triggers for guiding RBC transfusion for cardiovascular surgery: a systematic review and meta-analysis*.

scientific article

Trials directly comparing alternative spontaneous breathing trial techniques: a systematic review and meta-analysis

scientific article

Utility of Gram stain in the clinical management of suspected ventilator-associated pneumonia. Secondary analysis of a multicenter randomized trial

scientific article published on 01 March 2008

Venous thromboembolism and bleeding in critically ill patients with severe renal insufficiency receiving dalteparin thromboprophylaxis: prevalence, incidence and risk factors

scientific article published on 3 March 2008

Vital signs after cardiac arrest following withdrawal of life-sustaining therapy: a multicenter prospective observational study

scientific article published on November 2014

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