List of works - Sebastian Springer

A two-hybrid antibody micropattern assay reveals specific interactions of MHC I heavy chains at the cell surface

article

Comparative validation of a microcapsule-based immunoassay for the detection of proteins and nucleic acids

scientific article published on 20 July 2018

Controlled intracellular release of peptides from microcapsules enhances antigen presentation on MHC class I molecules

scientific article published on October 2009

Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity

scientific article

Determining the activity of the transporter associated with antigen processing in the compartments of the secretory pathway

scientific article published on 01 January 2013

Differential tapasin dependence of MHC class I molecules correlates with conformational changes upon peptide dissociation: a molecular dynamics simulation study

scientific article published on 18 July 2008

Dipeptides promote folding and peptide binding of MHC class I molecules

scientific article published on 03 September 2013

Dissociation of β2m from MHC class I triggers formation of noncovalent transient heavy chain dimers

scientific article published in 2022

Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells

scientific article published on 01 July 2019

Endoplasmic reticulum targeting alters regulation of expression and antigen presentation of proinsulin

scientific article published on 28 April 2014

Fast Association Rates Suggest a Conformational Change in the MHC Class I Molecule H-2Dbupon Peptide Binding

article

Flexibility of the MHC class II peptide binding cleft in the bound, partially filled, and empty states: a molecular dynamics simulation study

scientific article published in January 2009

High-throughput peptide-MHC complex generation and kinetic screenings of TCRs with peptide-receptive HLA-A*02:01 molecules

scientific article published on 01 July 2019

Investigating MHC class I folding and trafficking with pulse-chase experiments

scientific article published on 15 February 2013

MHC Class I Stability is Modulated by Cell Surface Sialylation in Human Dendritic Cells

scientific article published on 10 March 2020

Not all empty MHC class I molecules are molten globules: tryptophan fluorescence reveals a two-step mechanism of thermal denaturation

scientific article published on 4 February 2013

Nucleation of COPII Vesicular Coat Complex by Endoplasmic Reticulum to Golgi Vesicle SNAREs ⬇️

scientific article published on July 31, 1998

Opening opportunities for Kd determination and screening of MHC peptide complexes

scientific article published in 2022

Peptide-receptive major histocompatibility complex class I molecules cycle between endoplasmic reticulum and cis-Golgi in wild-type lymphocytes

scientific article published on 26 July 2007

Procathepsin V Is Secreted in a TSH Regulated Manner from Human Thyroid Epithelial Cells and Is Accessible to an Activity-Based Probe

scientific article published on 30 November 2020

Proline substitution independently enhances H-2D(b) complex stabilization and TCR recognition of melanoma-associated peptides

scientific article

Protein micropatterns printed on glass: Novel tools for protein-ligand binding assays in live cells

scientific article published on 15 September 2017

Regulated oligomerization induces uptake of a membrane protein into COPII vesicles independent of its cytosolic tail

scientific article published on 25 February 2014

Retrieval of a Metabolite from Cells with Polyelectrolyte Microcapsules

article

Stoichiometry of HLA class II-invariant chain oligomers

scientific article

Structure of the Sec23p/24p and Sec13p/31p complexes of COPII

scientific article

Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection

scientific article published on 11 March 2020

Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin

scientific article published on 26 February 2019

TAP-Dependent and -Independent Peptide Import into Dendritic Cell Phagosomes

scientific article published on 23 September 2016

Tapasin and other chaperones: models of the MHC class I loading complex.

scientific article published in September 2004

Tapasin dependence of major histocompatibility complex class I molecules correlates with their conformational flexibility.

scientific article

Tapasin edits peptides on MHC class I molecules by accelerating peptide exchange.

scientific article

The mechanism of action of tapasin in the peptide exchange on MHC class I molecules determined from kinetics simulation studies

scientific article (publication date: June 2009)

Trace Amine-Associated Receptor 1 Trafficking to Cilia of Thyroid Epithelial Cells

scientific article published on 16 June 2021

List of works by Sebastian Springer

A two-hybrid antibody micropattern assay reveals specific interactions of MHC I heavy chains at the cell surface

Comparative validation of a microcapsule-based immunoassay for the detection of proteins and nucleic acids

Controlled intracellular release of peptides from microcapsules enhances antigen presentation on MHC class I molecules

Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity

Determining the activity of the transporter associated with antigen processing in the compartments of the secretory pathway

Differential tapasin dependence of MHC class I molecules correlates with conformational changes upon peptide dissociation: a molecular dynamics simulation study

Dipeptides promote folding and peptide binding of MHC class I molecules

Dissociation of β2m from MHC class I triggers formation of noncovalent transient heavy chain dimers

Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells

Endoplasmic reticulum targeting alters regulation of expression and antigen presentation of proinsulin

Fast Association Rates Suggest a Conformational Change in the MHC Class I Molecule H-2Dbupon Peptide Binding

Flexibility of the MHC class II peptide binding cleft in the bound, partially filled, and empty states: a molecular dynamics simulation study

High-throughput peptide-MHC complex generation and kinetic screenings of TCRs with peptide-receptive HLA-A*02:01 molecules

Investigating MHC class I folding and trafficking with pulse-chase experiments

MHC Class I Stability is Modulated by Cell Surface Sialylation in Human Dendritic Cells

Not all empty MHC class I molecules are molten globules: tryptophan fluorescence reveals a two-step mechanism of thermal denaturation

Nucleation of COPII Vesicular Coat Complex by Endoplasmic Reticulum to Golgi Vesicle SNAREs ⬇️

Opening opportunities for Kd determination and screening of MHC peptide complexes

Peptide-receptive major histocompatibility complex class I molecules cycle between endoplasmic reticulum and cis-Golgi in wild-type lymphocytes

Procathepsin V Is Secreted in a TSH Regulated Manner from Human Thyroid Epithelial Cells and Is Accessible to an Activity-Based Probe

Proline substitution independently enhances H-2D(b) complex stabilization and TCR recognition of melanoma-associated peptides

Protein micropatterns printed on glass: Novel tools for protein-ligand binding assays in live cells

Regulated oligomerization induces uptake of a membrane protein into COPII vesicles independent of its cytosolic tail

Retrieval of a Metabolite from Cells with Polyelectrolyte Microcapsules

Stoichiometry of HLA class II-invariant chain oligomers

Structure of the Sec23p/24p and Sec13p/31p complexes of COPII

Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection

Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin

TAP-Dependent and -Independent Peptide Import into Dendritic Cell Phagosomes

Tapasin and other chaperones: models of the MHC class I loading complex.

Tapasin dependence of major histocompatibility complex class I molecules correlates with their conformational flexibility.

Tapasin edits peptides on MHC class I molecules by accelerating peptide exchange.

The mechanism of action of tapasin in the peptide exchange on MHC class I molecules determined from kinetics simulation studies

Trace Amine-Associated Receptor 1 Trafficking to Cilia of Thyroid Epithelial Cells